Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance

scientific article

Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0966-3274(03)00047-9
P698PubMed publication ID12967781

P50authorMilica Vukmanovic-StejicQ46152514
Leonie S. TaamsQ55277361
P2093author name stringMike Salmon
Milica Vukmanovic-Stejic
Arne Akbar
P2860cites workCytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetesQ28143530
Multiple immuno-regulatory defects in type-1 diabetesQ28344695
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 productionQ29619536
Regulatory T cells in autoimmmunity*.Q33904108
Regulatory T cells: key controllers of immunologic self-toleranceQ33941140
Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitroQ33942128
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Regulatory T cells in the control of immune pathology.Q34348983
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance.Q34516841
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor betaQ34517421
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.Q34518941
CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host diseaseQ34525987
Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.Q34529123
Inhibition of human CD4(+)CD25(+high) regulatory T cell functionQ34529239
Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cellsQ77584357
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient miceQ78022304
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethalityQ78033315
Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapyQ78488897
CD25+ immunoregulatory CD4 T cells mediate acquired central transplantation toleranceQ78701766
CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in miceQ78701808
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunityQ34529549
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharideQ34531452
Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of actionQ36350238
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cellsQ36369536
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.Q36370315
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsivenessQ36370807
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responsesQ36376333
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigenQ40701079
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.Q40801370
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecificQ40910998
Anergic T cells as suppressor cells in vitroQ41461549
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].Q41907086
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cellsQ41908906
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human bloodQ41973912
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral bloodQ41988688
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
TRANCE-RANK, a new signal pathway involved in lymphocyte development and T cell activationQ42944002
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsQ42944333
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cellsQ42947524
A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral bloodQ46284741
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependencyQ47992795
Tracking the immunoregulatory mechanisms active during allograft toleranceQ49022949
Peptide specificity of thymic selection of CD4+CD25+ T cells.Q51058071
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.Q52011695
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation toleranceQ56904417
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferationQ56904469
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponsesQ56904642
CD4(+)CD25(+) T cells facilitate the induction of T cell anergyQ56904876
Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administrationQ56904883
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
CD4 CD25 regulatory T cells are not functionally impaired in adult patients with IgE-mediated cow's milk allergyQ61651905
‘Anergic’ T cells Modulate the T-cell Activating Capacity of Antigen-presenting CellsQ61651911
Anergic T cells actively suppress T cell responses via the antigen-presenting cellQ61651916
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic miceQ71641038
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10Q73509865
CD4(+), CD25(+) T cells as regulators of alloimmune responsesQ73667423
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptideQ73688337
Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone populationQ73740429
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cellsQ74012969
Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulationQ74080415
Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cellsQ74244102
Natural CD4 CD25(+) regulatory T cells control the burst of superantigen-induced cytokine production: the role of IL-10Q77542537
P433issue3-4
P304page(s)277-285
P577publication date2003-07-01
P1433published inTransplant ImmunologyQ15758510
P1476titleImmune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance
P478volume11

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cites work (P2860)
Q90704712Accumulation of High Levels of Monocytic Myeloid-Derived Suppressor Cells Enhances Graft Survival in Almost-Tolerant Kidney Transplant Recipients
Q54363666Antigen-specific T-regulatory cells can extend skin graft survival time in mice.
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Q54419413Differentially modulated dendritic cells induce regulatory T cells with different characteristics.
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Q34349909Role of CD4CD25FOXP3 Regulatory T Cells in Psoriasis
Q46894286The influence of immuosuppressive therapy on the development of CD4+CD25+ T cells after renal transplantation.

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