Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis

scientific article published on April 25, 2012

Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.1200109
P953full work available online athttps://doi.org/10.4049/jimmunol.1200109
https://europepmc.org/articles/PMC3358586
https://europepmc.org/articles/PMC3358586?pdf=render
https://journals.aai.org/jimmunol/article-pdf/188/11/5785/1351870/1200109.pdf
https://www.jimmunol.org/content/jimmunol/188/11/5785.full.pdf
P932PMC publication ID3358586
P698PubMed publication ID22539790
P5875ResearchGate publication ID224856105

P2093author name stringDongchun Liang
Deming Sun
Hui Shao
Aijun Zuo
Henry J. Kaplan
Rebecca L. O'Brien
Willi K. Born
P2860cites workCD28 co-stimulation down regulates Th17 developmentQ21143804
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17Q28213628
Immunobiology of dendritic cellsQ29547465
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Q29547855
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineagesQ29547871
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cellsQ29618163
Phenotypic and functional features of human Th17 cellsQ29619323
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionQ29619536
Major role of gamma delta T cells in the generation of IL-17+ uveitogenic T cellsQ33829024
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitisQ79755041
The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cellsQ80582218
Understanding the IL-23-IL-17 immune pathwayQ81485100
Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cellsQ82732264
Regulatory T cells in autoimmmunity*.Q33904108
Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune diseaseQ34132578
Regulatory effect of gammadelta T cells on IL-17+ uveitogenic T cellsQ34135581
Expression of functional interleukin 2 receptors by peripheral blood monocytes from patients with active pulmonary tuberculosisQ34252586
A shared epitope of the interphotoreceptor retinoid-binding protein recognized by the CD4+ and CD8+ autoreactive T cellsQ34448277
CD4+ CD25+ suppressor T cells: more questions than answersQ34716304
Activated gammadelta T cells promote the activation of uveitogenic T cells and exacerbate EAU developmentQ35684372
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T LymphocytesQ36401622
T(H)-17 cells in the circle of immunity and autoimmunityQ36765453
CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cellsQ37070645
Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitisQ37593413
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cellsQ38336314
T cell receptors in murine autoimmune diseasesQ38624475
Low-strength T-cell activation promotes Th17 responses.Q39338146
The interleukin 2 receptorQ39602358
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecificQ40910998
Regulatory T cells in experimental allergic encephalomyelitis. I. Frequency and specificity analysis in normal and immune rats of a T cell subset that inhibits diseaseQ40957951
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
Structures on the I-A molecule predisposing for susceptibility to type II collagen-induced autoimmune arthritisQ42633703
A CD4 cell is capable of transferring suppression of collagen-induced arthritis.Q44359227
Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes.Q44677540
Immune responses to retinal self-antigens in CD25(+)CD4(+) regulatory T-cell-depleted miceQ44909641
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune interventionQ46499427
Severe chronic experimental autoimmune uveitis (EAU) of the C57BL/6 mouse induced by adoptive transfer of IRBP1-20-specific T cellsQ46672057
Short-term anti-CD25 monoclonal antibody treatment and neogenetic CD4(+)CD25(high) regulatory T cells in kidney transplantationQ46696973
Cutting edge: ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitisQ47810532
Does the IL-2 receptor alpha chain induced on dendritic cells have a biological function?Q52529943
Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animalsQ57281022
T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the ratQ57281273
Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic proteinQ59053168
CD4 T cell activation by myelin oligodendrocyte glycoprotein is suppressed by adult but not cord blood CD25+ T cellsQ59526699
Cell surface marker analysis of mouse thymic dendritic cellsQ67514688
The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymusQ69936089
Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigensQ70537823
Administration of anti-interleukin-2 receptor alpha antibody in vivo induces localized autoimmune diseaseQ71425950
Heterogeneity of rat encephalitogenic T cells elicited by variants of the myelin basic protein (68-86) peptideQ71701871
Interleukin 2 enhancement of lymphokine secretion by T lymphocytes: analysis of established clones and primary limiting dilution microculturesQ72815601
Expression of functional IL-2 receptors on mature splenic dendritic cellsQ73812511
The role of regulatory T cells in Lewis rats resistant to EAEQ74377608
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
uveitisQ280027
P304page(s)5785-5791
P577publication date2012-04-25
P1433published inJournal of ImmunologyQ3521441
P1476titleRole of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis
Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis
P478volume188

Reverse relations

cites work (P2860)
Q36410586A2B adenosine receptor activation switches differentiation of bone marrow cells to a CD11c(+)Gr-1(+) dendritic cell subset that promotes the Th17 response
Q34988261Anti-inflammatory or proinflammatory effect of an adenosine receptor agonist on the Th17 autoimmune response is inflammatory environment-dependent
Q35937473CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis
Q90132484CD83 orchestrates immunity toward self and non-self in dendritic cells
Q28591068EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells
Q51016364Forkhead box protein 3 demethylation is associated with tolerance induction in peanut-induced intestinal allergy
Q46132169Functional Conversion and Dominance of γδ T Subset in Mouse Experimental Autoimmune Uveitis
Q55432885High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of γδ T cells in the autoimmune responses of EAU.
Q37038620IL-23 receptor expression on γδ T cells correlates with their enhancing or suppressive effects on autoreactive T cells in experimental autoimmune uveitis
Q35572220Increased CD1c+ mDC1 with mature phenotype regulated by TNFα-p38 MAPK in autoimmune ocular inflammatory disease
Q24625664Interleukin-17 production and T helper 17 cells in peripheral blood mononuclear cells in response to ocular lysate in patients with birdshot chorioretinopathy
Q34956173Levels of blood CD1c+ mDC1 and CD1chi mDC1 subpopulation reflect disease activity in noninfectious uveitis
Q38839628Manipulating Memory CD8 T Cell Numbers by Timed Enhancement of IL-2 Signals
Q36655815Regulation of Adenosine Deaminase on Induced Mouse Experimental Autoimmune Uveitis
Q37254342Regulatory T cells control strain specific resistance to Experimental Autoimmune Prostatitis
Q36880106Retinoic acid inhibits CD25+ dendritic cell expansion and γδ T-cell activation in experimental autoimmune uveitis
Q26852793Role of dendritic cell subsets in immunity and their contribution to noninfectious uveitis
Q55488025Streptococcus suis Serotype 2 Infection Impairs Interleukin-12 Production and the MHC-II-Restricted Antigen Presentation Capacity of Dendritic Cells.
Q45972858TLR7 Engagement on Dendritic Cells Enhances Autoreactive Th17 Responses via Activation of ERK.
Q92999338The Purinergic System as a Pharmacological Target for the Treatment of Immune-Mediated Inflammatory Diseases

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