Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 (scientific article (publication date: 17 January 2003))

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Q33907311	IL-23/IL-27 Ratio in Peripheral Blood of Patients with Breast Cancer
Q28282812	IL-23: changing the verdict on IL-12 function in inflammation and autoimmunity
Q38040747	IL-23: one cytokine in control of autoimmunity
Q40063804	IL-23R-activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity
Q38729193	IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice.
Q34003280	IL-6 as a druggable target in psoriasis: focus on pustular variants
Q84593093	IL-6 blockade preferentially inhibits Th17 differentiation in collagen-induced arthritis
Q29614839	IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Q37132980	IL-6 promotes NK cell production of IL-17 during toxoplasmosis
Q44162764	IL-6 regulates neutrophil microabscess formation in IL-17A-driven psoriasiform lesions
Q48275402	IL17A and IL23R gene polymorphisms affect the clinical features and prognosis of patients with multiple myeloma.
Q42280446	IL17A gene polymorphisms, serum IL-17A and IgE levels, and hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection
Q31036486	IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection
Q36882237	IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
Q38468925	Identification of Acvr2a as a Th17 cell-specific gene induced during Th17 differentiation
Q42170048	Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells
Q24296262	Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F
Q51757389	Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: the serum cytokine profile and peripheral cell population.
Q37267375	Immune defence mechanisms and immunoenhancement strategies in oropharyngeal candidiasis
Q38137189	Immune regulation of bone loss by Th17 cells in oestrogen-deficient osteoporosis
Q45174642	Immunization with Bivalent Flagellin Protects Mice against Fatal Pseudomonas aeruginosa Pneumonia.
Q33911650	Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen
Q35140973	Immunodeficiency lentiviral infections in natural and non-natural hosts
Q37315226	Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow
Q37802002	Immunological aspect of cardiac remodeling: T lymphocyte subsets in inflammation-mediated cardiac fibrosis
Q36993451	Immunological decision-making: how does the immune system decide to mount a helper T-cell response?
Q37224656	Immunology and oxidative stress in multiple sclerosis: clinical and basic approach.
Q34022013	Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant
Q80505165	Immunopathogenesis of inflammatory bowel disease
Q37982064	Immunopathological roles of cytokines, chemokines, signaling molecules, and pattern-recognition receptors in systemic lupus erythematosus
Q38959155	Immunopathology alters Th17 cell glucocorticoid sensitivity
Q34932088	Immunoregulatory cytokines are associated with protection from immunopathology following Mycobacterium avium subspecies paratuberculosis infection in red deer
Q37328591	In vitro assays of allosensitization
Q35783661	In vivo priming of IL-17(+) uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation
Q51040346	Increased IL-17 production by peripheral T helper cells after tumour necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression.
Q79782031	Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women
Q36481651	Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10
Q33644230	Increased expression of CD25, CD83, and CD86, and secretion of IL-12, IL-23, and IL-10 by human dendritic cells incubated in the presence of Toll-like receptor 2 ligands and Giardia duodenalis
Q24676186	Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
Q82663765	Increased plasma levels of IL-21 and IL-23 in spondyloarthritis are not associated with clinical and MRI findings
Q34484151	Increased pulmonary tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-17A responses compensate for decreased gamma interferon production in anti-IL-12 autovaccine-treated, Mycobacterium bovis BCG-vaccinated mice
Q37318879	Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells
Q37179608	Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis
Q28585931	Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
Q37311131	Induction, function and regulation of IL-17-producing T cells
Q48055540	Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC, thymus, and lung lymphocytes of young pigs
Q37883443	Inflamed gut mucosa: downstream of interleukin-10.
Q42104777	Inflammatory Th17 Cells Express Integrin αvβ3 for Pathogenic Function
Q37354747	Inflammatory cytokines in pediatric obstructive sleep apnea
Q27005445	Inflammatory pathways of importance for management of inflammatory bowel disease
Q33911969	Inflammatory skin disease in K5.hTGF-beta1 transgenic mice is not dependent on the IL-23/Th17 inflammatory pathway
Q84942990	Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis
Q34349990	Influence of IL17A polymorphisms on the aberrant methylation of DAPK and CDH1 in non-cancerous gastric mucosa
Q27304398	Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel
Q45980367	Inhibition of connective tissue growth factor ameliorates disease in a murine model of rheumatoid arthritis.
Q33608575	Innate IL-17-producing cells: the sentinels of the immune system
Q39902875	Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease
Q38916194	Innate lymphoid cells: models of plasticity for immune homeostasis and rapid responsiveness in protection.
Q42747718	Innate-like function of memory Th17 cells for enhancing endotoxin-induced acute lung inflammation through IL-22
Q36367126	Integrating longitudinal serum IL-17 and IL-23 follow-up, along with autoantibodies variation, contributes to predict bullous pemphigoid outcome
Q37029422	Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock
Q38477579	Interaction network analysis revealed biomarkers in myocardial infarction
Q37623410	Interactions between neutrophils, Th17 cells, and chemokines during the initiation of experimental model of multiple sclerosis
Q30251957	Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review.
Q39297697	Interferon-alpha and viral triggers promote functional maturation of human monocyte-derived dendritic cells
Q38674886	Interleukin (IL)-12 and IL-23 and Their Conflicting Roles in Cancer
Q24303817	Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
Q33590409	Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.
Q28395500	Interleukin 12 a key immunoregulatory cytokine in infection applications
Q37319920	Interleukin 17 production among patients with American cutaneous leishmaniasis
Q29547871	Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Q80102514	Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation
Q34556912	Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
Q80102518	Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Q37204671	Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control
Q34248780	Interleukin-12: an update on its immunological activities, signaling and regulation of gene expression
Q58411438	Interleukin-17 and interleukin-23: importance in the pathogenesis of lung impairment in patients with systemic sclerosis
Q37728837	Interleukin-17 and its expanding biological functions.
Q37552021	Interleukin-17 and systemic lupus erythematosus: current concepts
Q37350011	Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice
Q38430722	Interleukin-17 in systemic lupus erythematosus: A comprehensive review
Q35072565	Interleukin-17 in various ocular surface inflammatory diseases
Q50929994	Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity.
Q47689166	Interleukin-17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis.
Q36835789	Interleukin-17: a new paradigm in inflammation, autoimmunity, and therapy
Q35675887	Interleukin-17: the missing link between T-cell accumulation and effector cell actions in rheumatoid arthritis?
Q37512884	Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance
Q89762380	Interleukin-17A and Keratinocytes in Psoriasis
Q36524875	Interleukin-17A and interleukin-23 in morphea.
Q35913387	Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection
Q37883457	Interleukin-23 and T helper 17-type responses in intestinal inflammation: from cytokines to T-cell plasticity
Q37947514	Interleukin-23 as a potential therapeutic target for rheumatoid arthritis
Q24677051	Interleukin-23 drives innate and T cell-mediated intestinal inflammation
Q89519257	Interleukin-23 engineering improves CAR T cell function in solid tumors
Q41960791	Interleukin-23 is required for development of arthritis in mice vaccinated and challenged with Borrelia species
Q43276051	Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients
Q54361986	Interleukin-23 receptor polymorphism as a risk factor for oral cancer susceptibility.
Q40313360	Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection.
Q37404716	Interleukin-23/Th17 pathways and inflammatory bowel disease
Q28080986	Interleukin-23R rs7517847 T/G Polymorphism Contributes to the Risk of Crohn's Disease in Caucasians: A Meta-Analysis
Q38848936	Interleukin-27 as a Novel Therapy for Inflammatory Bowel Disease: A Critical Review of the Literature
Q26829619	Interleukin-35: Expanding Its Job Profile
Q37073886	Interleukin-35: odd one out or part of the family?
Q37273910	Interleukins 17 and 23 influence the host response to Histoplasma capsulatum
Q29618163	Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
Q37773302	Interleukins and cancer immunotherapy.
Q37276852	Interplay between effector Th17 and regulatory T cells
Q35714248	Interrelatedness between dysbiosis in the gut microbiota due to immunodeficiency and disease penetrance of colitis
Q36572940	Intersection of population variation and autoimmunity genetics in human T cell activation
Q55259683	Intraperitoneal administration of the anti-IL-23 antibody prevents the establishment of intestinal nematodes in mice.
Q37159061	Invariant NKT cells inhibit development of the Th17 lineage
Q37421251	Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis
Q33455780	Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients
Q61649471	JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis
Q35046775	Jagged-1 signaling suppresses the IL-6 and TGF-β treatment-induced Th17 cell differentiation via the reduction of RORγt/IL-17A/IL-17F/IL-23a/IL-12rb1
Q37346779	Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.
Q47692110	Kynurenic acid downregulates IL-17/1L-23 axis in vitro
Q53523235	Lack of association between interleukin 23 receptor gene polymorphisms and rheumatoid arthritis susceptibility.
Q39265291	Late developmental plasticity in the T helper 17 lineage
Q35976768	Leprosy Reactions Show Increased Th17 Cell Activity and Reduced FOXP3+ Tregs with Concomitant Decrease in TGF-β and Increase in IL-6
Q34489206	Lineage-specific Effects of 1,25-Dihydroxyvitamin D3 on the Development of Effector CD4 T Cells
Q34490941	Lipocalin 2 regulates inflammation during pulmonary mycobacterial infections.
Q47349998	Live Attenuated Leishmania donovani Centrin Gene-Deleted Parasites Induce IL-23-Dependent IL-17-Protective Immune Response against Visceral Leishmaniasis in a Murine Model
Q37785522	Liver ischemia/reperfusion injury: Processes in inflammatory networks-A review
Q34350569	Loss and dysregulation of Th17 cells during HIV infection
Q59090565	Macrophage migration inhibitory factor stimulates interleukin-17 expression and production in lymph node cells
Q33613852	Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses
Q36468059	Mammalian gut immunity.
Q53828883	Management of Moderate to Severe Plaque Psoriasis: The Emerging Role of IL-17 Inhibition.
Q46262713	Marked diversity of IL23R gene haplotype variants in rheumatoid arthritis comparing with Crohn's disease and ankylosing spondylitis
Q41891115	Marked induction of c-Maf protein during Th17 cell differentiation and its implication in memory Th cell development
Q37372628	Massive but selective cytokine dysregulation in the colon of IL-10-/- mice revealed by multiplex analysis
Q34678846	Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferation
Q91894657	Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs)
Q51704302	Mesenchymal stem cells improve the outcomes of liver recipients via regulating CD4+ T helper cytokines in rats.
Q86530888	Mesenchymal stem cells inhibit Th17 cells differentiation via IFN-γ-mediated SOCS3 activation
Q46774147	Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.
Q37172065	MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expression
Q36839871	Microbial-induced Th17: superhero or supervillain?
Q59795977	Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
Q92440328	Midkine level may be used as a noninvasive biomarker in Crohn’s disease
Q37331068	Modulation of cytokines and transcription factors (T-Bet and GATA3) in CD4 enriched cervical cells of Chlamydia trachomatis infected fertile and infertile women upon stimulation with chlamydial inclusion membrane proteins B and C.
Q34169114	Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).
Q37873404	Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily
Q42589687	Molecular mechanisms of mouse skin tumor promotion
Q34409404	Monoclonal antibodies in multiple sclerosis treatment: current and future steps
Q33728334	More stories on Th17 cells
Q27011014	Multiple sclerosis: the role of cytokines in pathogenesis and in therapies
Q35880106	Mutated major histocompatibility complex class II transactivator up-regulates interleukin-33-dependent differentiation of Th2 subset through Nod2 binding for NLR (NOD-like receptor) signaling initiation
Q36598193	MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling
Q37256545	Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein activates dendritic cells and induces a Th1 polarization
Q43106558	Mycophenolic acid suppresses granulopoiesis by inhibition of interleukin-17 production
Q64075903	NCR group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development
Q24316237	Negative regulation of IL-17 production by OX40/OX40L interaction
Q37067780	Negative regulation of Th17 responses
Q41484934	Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine-Nanobody Complex
Q79236402	Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis
Q35166622	Neutralization of mouse interleukin-17 bioactivity inhibits corneal allograft rejection
Q35217462	Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection
Q41389903	Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model.
Q36184396	New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
Q89621631	New and Emerging Topical Therapies for Psoriasis and Atopic Dermatitis
Q37001149	New complexities in helper T cell fate determination and the implications for autoimmune diseases
Q34175958	New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression
Q37361936	New insights into the roles of dendritic cells in intestinal immunity and tolerance
Q37846678	New interleukin-23 pathway inhibitors in dermatology: ustekinumab, briakinumab, and secukinumab
Q34666072	New players in the cytokine orchestra of inflammatory bowel disease
Q35557349	No evidence for activation of T(H)1 or T(H)17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D.
Q41175731	Nocardia farcinica activates human dendritic cells and induces secretion of interleukin-23 (IL-23) rather than IL-12p70.
Q27660136	Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088
Q35107889	Novel IL-12 family members shed light on the orchestration of Th1 responses
Q37755334	Novel gene therapeutic strategies for the induction of tolerance in cornea transplantation
Q53295620	Novel interactions of a microbial superantigen with TLR2 and TLR4 differentially regulate IL-17 and Th17-associated cytokines.
Q35368022	Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions.
Q96950815	One road to the TH17 pathway: how TH1 led to TH17 (and vice versa), and first came last
Q45899456	Optimization of human Th17 cell differentiation in vitro: evaluating different polarizing factors.
Q33681689	Overexpression of interleukin-23 and interleukin-17 in the lesion of pemphigus vulgaris: a preliminary study
Q37135491	P2 purinergic receptor modulation of cytokine production
Q36043641	PGE2 Elevates IL-23 Production in Human Dendritic Cells via a cAMP Dependent Pathway
Q33591700	PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model
Q52597639	PKCδ-Mediated Nox2 Activation Promotes Fluid-Phase Pinocytosis of Antigens by Immature Dendritic Cells.
Q37231755	PPAR Regulation of Inflammatory Signaling in CNS Diseases
Q46744291	Paediatric-onset psoriasis is associated with ERAP1 and IL23R loci, LCE3C_LCE3B deletion and HLA-C*06.
Q37360652	Pathogenesis of myocarditis and dilated cardiomyopathy
Q96134668	Pathogenesis of psoriasis in the "omic" era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances
Q34998903	Pathological role of interleukin-17 in poly I:C-induced hepatitis
Q33552805	Periplocoside A prevents experimental autoimmune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells
Q42378984	Phage-assisted continuous evolution of proteases with altered substrate specificity
Q29619323	Phenotypic and functional features of human Th17 cells
Q38129871	Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases
Q37984817	Pivotal roles of the interleukin-23/T helper 17 cell axis in hepatitis B.
Q34300986	Plasmid interleukin-23 (IL-23), but not plasmid IL-27, enhances the protective efficacy of a DNA vaccine against Mycobacterium tuberculosis infection.
Q38729774	Platelet-activating factor induces Th17 cell differentiation
Q54404825	Polymorphisms of the IL23R gene are associated with psoriasis but not with immunoglobulin A nephropathy in a Hungarian population.
Q34376236	Positive and Negative Regulation of Th17 Cell Differentiation: Evaluating The Impact of RORC2.
Q33942532	Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization
Q49043582	Potential role of Th17 cells in the pathogenesis of adult-onset Still's disease
Q26863295	Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity
Q37630095	Precarious balance: Th17 cells in host defense.
Q42000043	Preparation, crystallization and preliminary X-ray diffraction studies of the glycosylated form of human interleukin-23.
Q34488588	Preventative role of interleukin-17 producing regulatory T helper type 17 (Treg 17) cells in type 1 diabetes in non-obese diabetic mice.
Q54390436	Primary biliary cholangitis: new treatments for an old disease.
Q36580442	Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.
Q48119915	Proinflammatory Cytokine IL-17 Shows a Significant Association with Helicobacter pylori Infection and Disease Severity
Q34181228	Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases
Q43162277	Prolonged ovalbumin challenge facilitates Th17 polarization in sensitized mice
Q37002699	Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor
Q37207581	Prospects for use of interleukin-12 as a mucosal adjuvant for vaccination of humans to protect against respiratory pneumococcal infection.
Q36948594	Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion
Q38906013	Protease-activated Receptor 1 Plays a Proinflammatory Role in Colitis by Promoting Th17-related Immunity.
Q36247264	Protection against Th17 cells differentiation by an interleukin-23 receptor cytokine-binding homology region
Q36481763	Protective immune mechanisms in helminth infection
Q34306734	Protective role of 5-lipoxigenase during Leishmania infantum infection is associated with Th17 subset
Q40387405	Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice
Q36921661	Psoriasis and psoriatic arthritis: separate or one and the same?
Q36917184	Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research
Q47724381	Psoriasis: from Pathogenesis to Targeted Therapies.
Q36648696	Psoriasis: genetic associations and immune system changes.
Q34033850	Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs
Q27026785	Putting together the psoriasis puzzle: an update on developing targeted therapies
Q34660473	RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.
Q37042876	Rapid αβ T-cell responses orchestrate innate immunity in response to Staphylococcal enterotoxin A.
Q24626339	Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells
Q34327203	Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
Q27860460	Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Q37373067	Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
Q39770778	Reduced TCR-dependent activation through citrullination of a T-cell epitope enhances Th17 development by disruption of the STAT3/5 balance
Q37348457	Regulation and function of proinflammatory TH17 cells
Q37128687	Regulation of FoxP3 regulatory T cells and Th17 cells by retinoids
Q26799975	Regulation of IL-17 in autoimmune diseases by transcriptional factors and microRNAs
Q42214713	Regulation of IL-17A expression in mice following subacute ozone exposure
Q33755232	Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis
Q34645439	Regulation of Th1/Th17 cytokines and IDO gene expression by inhibition of calpain in PBMCs from MS patients
Q37262374	Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.
Q37795583	Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27.
Q42129243	Regulation of defense responses against protozoan infection by interleukin-27 and related cytokines
Q54346247	Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production.
Q46226178	Regulatory T cells control VEGF-dependent skin inflammation
Q37550813	Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia
Q41157946	Regulatory T cells prevent inducible BALT formation by dampening neutrophilic inflammation.
Q37021703	Regulatory T cells vs Th17: differentiation of Th17 versus Treg, are the mutually exclusive?
Q36518989	Regulatory effects of C5a on IL-17A, IL-17F, and IL-23
Q37086693	Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines
Q39419911	Relevance of nuclear receptor expression in a Tchreg cell line, HOZOT: RXRα and PPARγ negatively regulate IFN-γ production.
Q85101810	Replication of association between interleukin-23 receptor (IL-23R) and its ligand (IL-12B) polymorphisms and psoriasis in the Chinese Han population
Q26991709	Review: The interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyond
Q37736941	Review: Toll-like receptors and NOD-like receptors in pulmonary antibacterial immunity
Q37998396	Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells
Q35981635	Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis
Q38572497	Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets
Q52956094	Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis
Q38270824	Role of IL-17 in Glioma Progression
Q37987880	Role of IL-17 in psoriasis and psoriatic arthritis
Q24605366	Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis
Q38190986	Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?
Q36795816	Role of TH-17 cells in rheumatic and other autoimmune diseases
Q37172965	Role of Th1 and Th17 cells in organ-specific autoimmunity.
Q38237647	Role of Th17 Cells in the Pathogenesis of Human IBD.
Q37622866	Role of Th17 cells and IL-17 in lung transplant rejection
Q36943381	Role of cytokine p40 family in multiple sclerosis
Q37735773	Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS.
Q37035188	Role of cytomegalovirus on the maturation and function of monocyte derived dendritic cells of liver transplant patients
Q34345547	Role of heat-stable enterotoxins in the induction of early immune responses in piglets after infection with enterotoxigenic Escherichia coli.
Q36379352	Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease
Q35671653	Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease
Q33814452	Role of interleukin-23 circulating levels increase in resected colorectal cancer before and after chemotherapy: preliminary data and future perspectives
Q38283980	Role of interleukin-23-dependent antifungal immune responses in dendritic cell-vaccinated mice
Q49956370	Role of the T and B lymphocytes in pathogenesis of autoimmune thyroid diseases
Q80598361	Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes
Q34975829	Role of transcription factor T-bet expression by CD4+ cells in gastritis due to Helicobacter pylori in mice
Q38579179	STAT3: a critical component in the response to Helicobacter pylori infection.
Q37001334	STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease
Q90744992	STAT4: an immunoregulator contributing to diverse human diseases
Q48148751	Safety and efficacy of guselkumab in Japanese patients with moderate-to-severe plaque psoriasis: a randomized, placebo-controlled, ascending-dose study
Q24547568	Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
Q36212815	Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody
Q37411201	Sequential evolution of IL-17 responses in the early period of allograft rejection.
Q36891896	Serum Levels of IL-17 and IL-23 in Patients With Rheumatic Mitral Stenosis
Q44736570	Serum concentration of IL-17, IL-23 and TNF-α among patients with chronic spontaneous urticaria: association with disease activity and autologous serum skin test
Q34235396	Severe malarial anemia: innate immunity and pathogenesis
Q42079929	ShiA abrogates the innate T-cell response to Shigella flexneri infection
Q50041283	Shifting the Focus: The Primary Role of IL-23 in Psoriasis and other Inflammatory Disorders.
Q37367853	Signal transduction and Th17 cell differentiation
Q35238480	Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
Q36571580	Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation
Q35951819	Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.
Q34901468	Silencing IL-23 expression by a small hairpin RNA protects against asthma in mice
Q28066288	Smad-dependent mechanisms of inflammatory bone destruction
Q37696996	Smad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse.
Q42690764	Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response
Q36207257	Stepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors.
Q24296669	Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
Q52729761	Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.
Q28068106	Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation
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Q24648045	Structure and signalling in the IL-17 receptor family
Q37051768	Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy
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Q33732092	Th17 cells: effector T cells with inflammatory properties
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Q89762937	Transcriptional profiling of human macrophages during infection with Bordetella pertussis
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Q37462596	Tristetraprolin down-regulates IL-23 expression in colon cancer cells
Q35749669	Tubular cross talk in acute kidney injury: a story of sense and sensibility
Q38050307	Tumor necrosis factor-alpha and the cytokine network in psoriasis
Q43169966	Unmasking of a protective tumor necrosis factor receptor I-mediated signal in the collagen-induced arthritis model
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Q33916253	Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis
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P356	DOI	10.1074/JBC.M207577200
P8608	Fatcat ID	release_l6u5sw7wrjdjjnazh2alp6td54
P3181	OpenCitations bibliographic resource ID	601267
P698	PubMed publication ID	12417590

P50	author	Nico Ghilardi	Q47160885
P2093	author name string	Frederic J de Sauvage
		Austin L Gurney
		Ming-Hong Xie
		Sudeepta Aggarwal
P433	issue	3
P407	language of work or name	English	Q1860
P921	main subject	T cell activation	Q14863969
		interleukins	Q194908
P304	page(s)	1910-4
P577	publication date	2003-01-17
P1433	published in	Journal of Biological Chemistry	Q867727
P1476	title	Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
P478	volume	278

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

scientific article (publication date: 17 January 2003)

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