The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models

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The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1006495203
P356DOI10.1186/AR1478
P932PMC publication ID1064899
P698PubMed publication ID15642151
P5875ResearchGate publication ID8089482

P50authorMarije KoendersQ38318056
P2093author name stringWim B van den Berg
Erik Lubberts
P2860cites workCloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine familyQ22011116
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CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri geneQ24315956
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesisQ24563235
RANK is essential for osteoclast and lymph node developmentQ24598872
Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transductionQ24676400
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokinesQ24678115
Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritisQ24681298
IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritisQ24796707
Anti-cytokine therapy in chronic destructive arthritisQ24805245
A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activityQ28119212
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Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in miceQ28206221
Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesisQ28208761
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17Q28213628
IL-17: prototype member of an emerging cytokine familyQ28214946
Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activityQ28272534
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25Q28592257
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptorQ28609151
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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainQ29614225
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitisQ29620481
Increased expression of interleukin 17 in inflammatory bowel diseaseQ29622829
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.Q33740453
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritisQ33908167
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defenseQ34087551
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Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB.Q34474493
Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airwaysQ34492076
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonistQ35022575
IL-17-induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen-activated protein (MAP) kinasesQ35043470
Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergyQ35083970
The role of IL-17 and family members in the pathogenesis of arthritisQ35165972
Effect of interleukin 17 on proteoglycan degradation in murine knee jointsQ35549425
Interleukin 17 synergises with tumour necrosis factor alpha to induce cartilage destruction in vitroQ35551055
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosionQ37202023
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosionQ40590532
IL-17 regulates gene expression and protein synthesis of the complement system, C3 and factor B, in skin fibroblastsQ40887975
NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cellsQ40956645
Elastase secreted by activated polymorphonuclear leucocytes causes chondrocyte damage and matrix degradation in intact articular cartilage: escape from inactivation by alpha-1-proteinase inhibitor.Q41557458
Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokinesQ41866942
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Reduction of interleukin-17-induced inhibition of chondrocyte proteoglycan synthesis in intact murine articular cartilage by interleukin-4.Q42489307
Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisciQ42511137
Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1betaQ42522382
Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient miceQ42620442
IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokinesQ42824130
Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destructionQ43945860
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responsesQ44158655
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines.Q47909675
Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesionsQ50232370
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.Q51687384
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.Q52032586
Microbial lipopeptides induce the production of IL-17 in Th cells.Q52968185
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balanceQ64378013
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritisQ64379692
Mitogen-activated protein kinase and nuclear factor kappaB together regulate interleukin-17-induced nitric oxide production in human osteoarthritic chondrocytes: possible role of transactivating factor mitogen-activated protein kinase-activated protQ73165868
Increased interleukin-17 production in patients with systemic sclerosisQ73202422
Interleukin-17 up-regulation of nitric oxide production in human osteoarthritis cartilageQ73414178
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanismQ73458527
Cell-cell contact of human T cells with fibroblasts changes lymphocytic mRNA expression: increased mRNA expression of interleukin-17 and interleukin-17 receptorQ73516728
Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytesQ73969172
Expression of IL-17 mRNA in ovarian cancerQ74008184
The combination of tumor necrosis factor alpha blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo modelQ74024097
IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophagesQ74412124
Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processesQ74602889
Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivoQ74829119
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synoviumQ77738643
Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitorsQ77787649
Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion proteinQ77838768
IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cellsQ78109562
Interleukin-17 promotes angiogenesis and tumor growthQ78460523
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient miceQ79317500
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcellQ7868
peptideQ172847
rheumatoid arthritisQ187255
interleukinsQ194908
biomedical investigative techniqueQ66648976
hemic and immune systemsQ70202933
P304page(s)29-37
P577publication date2004-11-30
P1433published inArthritis Research and TherapyQ15757229
P1476titleThe role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models
P478volume7

Reverse relations

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