The IL-17 cytokine family.

scientific article published on January 2006

The IL-17 cytokine family. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0083-6729(06)74010-9
P698PubMed publication ID17027518

P50authorJill M KramerQ57545487
P2093author name stringSarah L Gaffen
Fang Shen
Jeffrey J Yu
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IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesisQ24563235
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosisQ24605366
Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transductionQ24676400
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokinesQ24678115
IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-kappaB- and PI3-kinase/Akt-dependent pathwaysQ24793443
IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathwaysQ46156771
IL-17A augments TNF-alpha-induced IL-6 expression in airway smooth muscle by enhancing mRNA stabilityQ47913203
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A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF-alpha.Q50495241
Severe CD4 T cell-mediated immunopathology in murine schistosomiasis is dependent on IL-12p40 and correlates with high levels of IL-17.Q51989028
Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism.Q52014124
Regulation of immune and autoimmune responses by ICOS.Q53912899
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis.Q54638927
Expression and activity of IL-17 in cutaneous T-cell lymphomas (mycosis fungoides and Sezary syndrome).Q54706258
Interleukin-17 stimulates inducible nitric oxide synthase activation in rodent astrocytes.Q55473999
IL-17 enhances the susceptibility of U-2 OS osteosarcoma cells to NK cell lysisQ57003139
A fork in the pathway to inflammation and arthritisQ57232046
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balanceQ64378013
Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosusQ73086966
Mitogen-activated protein kinase and nuclear factor kappaB together regulate interleukin-17-induced nitric oxide production in human osteoarthritic chondrocytes: possible role of transactivating factor mitogen-activated protein kinase-activated protQ73165868
T-cell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-activated protein kinase cascade: role of distal sequences in the 3'-untranslated region of COX-2 mRNAQ73392461
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanismQ73458527
Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritisQ73806783
Expression of IL-17 mRNA in ovarian cancerQ74008184
CCAAT/enhancer-binding protein delta gene expression is mediated by autoregulation through downstream binding sitesQ74079283
Don't count your interleukins before they've hatchedQ74424915
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Interleukin-17 promotes angiogenesis and tumor growthQ78460523
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient miceQ79317500
T(H)-17: a giant step from T(H)1 and T(H)2Q81381452
The potential role of interleukin-17 in the immunopathology of periodontal diseaseQ81614905
A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signalingQ46107500
Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytesQ24817080
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsQ27860460
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Interleukin-17 family and IL-17 receptorsQ28185677
Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody productionQ28202510
Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in miceQ28206221
Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesisQ28208761
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivoQ28213431
Transforming growth factor-beta induces development of the T(H)17 lineageQ28237370
Interleukin-17 family members and inflammationQ28287876
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
Promotion and attenuation of FGF signaling through the Ras-MAPK pathwayQ28312210
Identification of Sef, a novel modulator of FGF signallingQ28312228
New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25Q28592257
Subnuclear localization of C/EBP beta is regulated by growth hormone and dependent on MAPKQ28594401
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptorQ28609151
IL-23 drives a pathogenic T cell population that induces autoimmune inflammationQ29547525
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Q29547855
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineagesQ29547871
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating ironQ29619561
Increased expression of interleukin 17 in inflammatory bowel diseaseQ29622829
Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient miceQ30308288
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.Q30436326
Inoculation of human interleukin-17 gene-transfected Meth-A fibrosarcoma cells induces T cell-dependent tumor-specific immunity in miceQ30693390
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infectionQ33556845
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.Q33740453
Expression of IL-17 in human memory CD45RO+ T lymphocytes and its regulation by protein kinase A pathwayQ33862141
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosisQ33862720
Sequential phosphorylation of CCAAT enhancer-binding protein beta by MAPK and glycogen synthase kinase 3beta is required for adipogenesisQ33896013
A domain in TNF receptors that mediates ligand-independent receptor assembly and signalingQ33907802
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritisQ33908167
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungsQ34033850
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defenseQ34087551
Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer.Q34101525
IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblastsQ34143188
Interleukin-17 induces src/MAPK cascades activation in human renal epithelial cellsQ34151371
Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate.Q34200792
Evidence for ligand-independent multimerization of the IL-17 receptorQ34279731
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is availableQ34432140
Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.Q34474419
Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB.Q34474493
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6Q34521302
Cytokine and cytokine receptor pleiotropy and redundancyQ34693494
Chemokines, cytokines and their receptors in Hodgkin's lymphoma cell lines and tissuesQ34700754
Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severityQ34945351
IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonistQ35022575
IL-17-induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen-activated protein (MAP) kinasesQ35043470
Neutrophil-mediated tissue injury in periodontal disease pathogenesis: findings from localized aggressive periodontitisQ35068805
Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergyQ35083970
The STIR-domain superfamily in signal transduction, development and immunityQ35135588
Interleukin 17 synergises with tumour necrosis factor alpha to induce cartilage destruction in vitroQ35551055
Inducible nitric oxide synthase activation by interleukin-17.Q35640431
The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signalingQ35947710
Neutrophils, interleukin-17A and lung diseaseQ36003968
Prototypic T cell receptor and CD4-like coreceptor are expressed by lymphocytes in the agnathan sea lampreyQ37513290
Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-alpha-induced genes in bone cellsQ38333262
The interleukin-17 gene of herpesvirus saimiri.Q39582413
Interleukin-17 stimulates inducible nitric oxide synthase-dependent toxicity in mouse beta cells.Q40356004
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesisQ40360012
Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitmentQ40563240
Interleukin (IL)-17 enhances tumor necrosis factor-alpha-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblastsQ40575542
Functional Cooperation between Interleukin-17 and Tumor Necrosis Factor-α Is Mediated by CCAAT/Enhancer-binding Protein Family MembersQ40619563
hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling.Q40637291
IL-17 expression in human herpetic stromal keratitis: modulatory effects on chemokine production by corneal fibroblasts.Q40691425
STAT1 is required for iNOS activation, but not IL-6 production in murine fibroblastsQ40830150
Induction of NF-kappaB by the Akt/PKB kinaseQ40950127
CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFsQ40955336
Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokinesQ41866942
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways.Q42264569
Interleukin-17: A new bone acting cytokine in vitroQ42476956
Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisciQ42511137
Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient miceQ42620442
IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock togetherQ42972111
IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediatorsQ43845883
IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblastsQ43997188
Down-regulation of proinflammatory capacity during apoptosis in human polymorphonuclear leukocytesQ44355424
Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts: role of interleukin-17.Q44490498
Crucial role for nuclear factor of activated T cells in T cell receptor-mediated regulation of human interleukin-17.Q45086536
Triptolide suppresses proinflammatory cytokine-induced matrix metalloproteinase and aggrecanase-1 gene expression in chondrocytesQ45209550
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in miceQ45876568
Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitisQ45886163
P304page(s)255-282
P577publication date2006-01-01
P1433published inVitamins and HormonesQ15753296
P1476titleThe IL-17 cytokine family
P478volume74

Reverse relations

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