Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

scientific article published on 21 December 2012

Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/CVR/CVS422
P932PMC publication ID3583258
P698PubMed publication ID23263331
P5875ResearchGate publication ID233976433

P2093author name stringBrett M Mitchell
Kristina J Young
Piyali Chatterjee
Valorie L Chiasson
Hoanglan Nguyen
Shelley E Kopriva
P2860cites workCutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine productionQ24291773
ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytesQ33549651
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunctionQ33642021
TLR signals promote IL-6/IL-17-dependent transplant rejection.Q33711191
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.Q33950554
Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?Q34443514
IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patientsQ73698956
Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitorsQ77787649
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activitiesQ79182194
Effect of fasudil on macrovascular disorder-induced endothelial dysfunctionQ79366253
Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunctionQ80264403
Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery diseaseQ80483198
Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertensionQ80552078
IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammationQ83187595
Myeloperoxidase (MPO) and interleukin-17 (IL-17) plasma levels are increased in patients with acute coronary syndromesQ84201343
New insights into the role of IL-17 in inflammatory bowel diseaseQ85043290
Inflammation, immunity, and hypertensionQ34528283
Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions.Q34583004
Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity.Q34765324
Inhibition of the AMP-activated protein kinase-α2 accentuates agonist-induced vascular smooth muscle contraction and high blood pressure in miceQ34950411
FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertensionQ35024911
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation.Q35456291
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunctionQ36229028
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylationQ36535244
The IL-17 cytokine family.Q36617097
An overview of IL-17 function and signalingQ37243055
Is hypertension an immunologic disease?Q37307983
The role of IL-23/IL-17 axis in lupus nephritisQ37397437
T lymphocytes: a role in hypertension?Q37664405
IL-17 in systemic lupus erythematosusQ37727813
Interleukin-17 and its target genes: mechanisms of interleukin-17 function in diseaseQ37735334
TGF-beta, IL-6, IL-17 and CTGF direct multiple pathologies of chronic cardiac allograft rejectionQ37773292
Association analysis of polymorphisms at the interleukin-1 locus in essential hypertensionQ37872597
Transforming growth factor-beta1 regulates macrophage migration via RhoA.Q38510172
Cellular mechanisms of IL-17-induced blood-brain barrier disruptionQ39770425
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide productionQ40638231
HIF-1α mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinomaQ40655023
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertensionQ41956748
Tacrolimus reduces nitric oxide synthase function by binding to FKBP rather than by its calcineurin effectQ42448517
FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressureQ42507560
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant ratsQ42515767
IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblastsQ43997188
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant ratsQ44715072
Mechanisms of soluble beta-amyloid impairment of endothelial functionQ45023573
In vivo effects of interleukin-17 on haematopoietic cells and cytokine release in normal miceQ45153206
IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling.Q45960055
Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsiaQ46332630
The effects of interleukin-6 on the contraction and relaxation responses of the cavernous smooth muscle from ratsQ46539077
IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophyQ46930205
Rho kinase regulates renal blood flow by modulating eNOS activity in ischemia-reperfusion of the rat kidneyQ46981497
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines.Q47909675
A pathogenic role of IL- 17 at the early stage of corneal allograft rejectionQ48025939
Serum levels of interleukin (IL)-13, IL-17 and IL-18 in patients with ischemic heart diseaseQ48029821
Renal NF-kappaB activation and TNF-alpha upregulation correlate with salt-sensitive hypertension in Dahl salt-sensitive rats.Q51937701
The effect of interleukin-17 on hematopoietic cells and cytokine release in mouse spleen.Q53944856
IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant ModelQ57273010
Rho kinase contributes to basal vascular tone in humans: role of endothelium-derived nitric oxideQ60722959
Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosusQ73086966
P433issue4
P921main subjectendotheliumQ111140
P304page(s)696-704
P577publication date2012-12-21
P1433published inCardiovascular ResearchQ4642329
P1476titleInterleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension
P478volume97