review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Anne M. Bowcock | Q30348371 |
P2093 | author name string | Liu Y | |
Krueger JG | |||
P2860 | cites work | Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation | Q24291049 |
Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties | Q24291982 | ||
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris | Q24676186 | ||
A haplotype map of the human genome | Q24679827 | ||
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis | Q28182995 | ||
A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis | Q28183038 | ||
Identification of six novel polymorphisms in the human corneodesmosin gene | Q28199751 | ||
Molecular physiology of cation-coupled Cl? cotransport: the SLC12 family | Q28203488 | ||
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci | Q28209261 | ||
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans | Q28211167 | ||
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 | Q28213628 | ||
Transforming growth factor-beta induces development of the T(H)17 lineage | Q28237370 | ||
Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein | Q28244075 | ||
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes | Q28248848 | ||
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis | Q28267921 | ||
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes | Q28271534 | ||
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. | Q28273794 | ||
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis | Q28303063 | ||
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia | Q28591205 | ||
Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q | Q28610601 | ||
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages | Q29547871 | ||
Runx transcription factors and the developmental balance between cell proliferation and differentiation. | Q30332928 | ||
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris | Q33757065 | ||
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. | Q34115785 | ||
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus | Q34116785 | ||
Human keratinocytes are a major source of cutaneous platelet-derived growth factor | Q34170407 | ||
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis | Q34220741 | ||
Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines | Q34234920 | ||
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a) | Q34245272 | ||
Point mutations of the RUNx1/AML1 gene in sporadic and familial myeloid leukemias | Q34448183 | ||
Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris | Q34468739 | ||
Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. | Q34474419 | ||
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiat | Q34505900 | ||
Systematic evaluation of association between the microsomal glutathione S-transferase 2 common variation and psoriasis vulgaris in Chinese population | Q34537967 | ||
S100 proteins in the epidermis | Q34548562 | ||
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene | Q34658035 | ||
Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression | Q35774136 | ||
Current concepts in the immunopathogenesis of psoriasis | Q35902657 | ||
The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor | Q36231140 | ||
Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing | Q36231924 | ||
Getting under the skin: the immunogenetics of psoriasis | Q36247085 | ||
Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases | Q36282160 | ||
Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells | Q36368842 | ||
Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development | Q36376366 | ||
Evidence for susceptibility determinant(s) to psoriasis vulgaris in or near PTPN22 in German patients | Q36993807 | ||
Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array | Q38356616 | ||
Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells | Q40395229 | ||
Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans population. | Q40506620 | ||
Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus | Q40725419 | ||
Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation | Q40734155 | ||
Expression of vascular endothelial growth factor in normal epidermis, epithelial tumors and cultured keratinocytes | Q42437628 | ||
Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept | Q42479845 | ||
Evaluation of the IRF-2 gene as a candidate for PSORS3. | Q42619643 | ||
Evidence for interaction between psoriasis-susceptibility loci on chromosomes 6p21 and 1q21. | Q42698848 | ||
Mapping of psoriasis to 17q terminus. | Q43073355 | ||
Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis. | Q43073651 | ||
Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis | Q43650481 | ||
IL-12 prevents the inhibitory effects of cis-urocanic acid on tumor antigen presentation by Langerhans cells: implications for photocarcinogenesis | Q43803680 | ||
Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. | Q45196039 | ||
Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis | Q46865521 | ||
A novel MGST2 non-synonymous mutation in a Chinese pedigree with psoriasis vulgaris | Q46960833 | ||
Memory effector (CD45RO+) and cytotoxic (CD8+) T cells appear early in the margin zone of spreading psoriatic lesions in contrast to cells expressing natural killer receptors, which appear late | Q47588197 | ||
Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling | Q47598277 | ||
Interleukin-10 promoter polymorphism IL10.G and familial early onset psoriasis | Q47672947 | ||
Psoriasis is not associated with IL-12p70/IL-12p40 production and IL12B promoter polymorphism | Q47721685 | ||
A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice | Q47758391 | ||
Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris. | Q48275426 | ||
Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders | Q49240008 | ||
CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. | Q52918582 | ||
Molecular characterization of a balanced chromosome translocation in psoriasis vulgaris | Q56974324 | ||
A non-HLA gene within the MHC in psoriasis | Q57149542 | ||
Psoriasis Susceptibility Locus on 18p Revealed by Genome Scan in Finnish Families Not Associated with PSORS1 | Q57232750 | ||
Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR | Q57275020 | ||
Association of TNF -238 and -308 Promoter Polymorphisms with Psoriasis Vulgaris and Psoriatic Arthritis but not with Pustulosis Palmoplantaris | Q57619885 | ||
Searching for Psoriasis Susceptibility Genes in Italy: Genome Scan and Evidence for a New Locus on Chromosome 1 | Q58193968 | ||
Prominent Production of IL-20 by CD68+/CD11c+ Myeloid-Derived Cells in Psoriasis: Gene Regulation and Cellular Effects | Q60683098 | ||
Psoriasis Genetics: The Way Forward | Q61647709 | ||
The genetics of psoriasis: a complex disorder of the skin and immune system | Q61647805 | ||
A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis | Q61853653 | ||
Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis | Q61990617 | ||
Changes in keratinocyte maturation during wound healing | Q69002778 | ||
Predominance of "memory" T cells (CD4+, CDw29+) over "naive" T cells (CD4+, CD45R+) in both normal and diseased human skin | Q69304365 | ||
Psoriasis and alpha-interferon | Q69883338 | ||
Psoriasis and HLA-Cw6 | Q71233054 | ||
Stratum corneum structure and function correlates with phenotype in psoriasis | Q71572086 | ||
The genetics of psoriasis | Q72765417 | ||
Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris | Q73778362 | ||
IL-10 promoter polymorphisms influence disease severity and course in psoriasis | Q73876813 | ||
Interleukin-10 promoter polymorphism in psoriasis | Q74025047 | ||
Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17(TIA-1)+CD8+CD3+ CTLs as determined by phenotypic analysis | Q74377163 | ||
Combined analysis of polymorphisms of the tumor necrosis factor-alpha and interleukin-10 promoter regions and polymorphic xenobiotic metabolizing enzymes in psoriasis | Q78197650 | ||
Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases | Q78553681 | ||
Cytokines and cytokine receptors | Q81013267 | ||
Possible relations between the polymorphisms of the cytokines IL-19, IL-20 and IL-24 and plaque-type psoriasis | Q81739598 | ||
P433 | issue | 1 | |
P304 | page(s) | 1-12 | |
P577 | publication date | 2006-11-09 | |
P1433 | published in | Genes and Immunity | Q15745246 |
P1476 | title | Psoriasis: genetic associations and immune system changes | |
P478 | volume | 8 |
Q40190310 | 1,4-dihydroxy-2-naphthoic Acid Induces Apoptosis in Human Keratinocyte: Potential Application for Psoriasis Treatment. |
Q48271832 | 9-cis-rich β-carotene powder of the alga Dunaliella reduces the severity of chronic plaque psoriasis: a randomized, double-blind, placebo-controlled clinical trial |
Q21145042 | A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci |
Q33769731 | A systems model for immune cell interactions unravels the mechanism of inflammation in human skin |
Q36751614 | Allele-specific cytokine responses at the HLA-C locus: implications for psoriasis |
Q52850152 | An integrated classification of pediatric inflammatory diseases, based on the concepts of autoinflammation and the immunological disease continuum. |
Q38101953 | Angiotensin-converting enzyme gene polymorphisms and the risk of psoriasis: a meta-analysis |
Q44295692 | Association analysis of BANK1 gene with psoriasis in Southern Han Chinese |
Q26772143 | Association between Psoriasis and Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis |
Q54967829 | Association between psoriasis and asthma risk: A meta-analysis. |
Q36993602 | Association of Serum Uric Acid Levels in Psoriasis: A Systematic Review and Meta-Analysis |
Q37307801 | Biological drugs targeting the immune response in the therapy of psoriasis |
Q35953653 | Comorbidities of Psoriasis - Exploring the Links by Network Approach |
Q34112840 | Current status and new developments in the treatment of psoriasis and psoriatic arthritis with biological agents |
Q37994612 | Cytokine-based therapy in psoriasis |
Q42637380 | Dermatology in the postgenomic era: harnessing human variation for personalized medicine |
Q35620533 | Effect of psoriasis activity on serum adiponectin and leptin levels. |
Q34050809 | Enhancement of keratinocyte differentiation by rose absolute oil. |
Q55020325 | Erythrodermic psoriasis: pathophysiology and current treatment perspectives. |
Q90589213 | Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders |
Q91259660 | Extra-adrenal glucocorticoid synthesis at epithelial barriers |
Q39570426 | Genetic polymorphisms of NFκB1 -94 del/ins ATTG, NFκB1A 2758 A>G and SUMO rs237025 G>A in psoriasis |
Q34428875 | Halting angiogenesis by non-viral somatic gene therapy alleviates psoriasis and murine psoriasiform skin lesions |
Q42013622 | Human beta-defensin 3 induces maturation of human langerhans cell-like dendritic cells: an antimicrobial peptide that functions as an endogenous adjuvant |
Q37407423 | Lack of evidence for activation of the hedgehog pathway in psoriasis |
Q64250717 | Level of inflammatory cytokines tumour necrosis factor α, interleukins 12, 23 and 17 in patients with psoriasis in the context of metabolic syndrome |
Q34941232 | Metabolic changes in psoriatic skin under topical corticosteroid treatment |
Q37891799 | NK cells and psoriasis |
Q37535998 | Patented small molecules against psoriasis |
Q36742020 | Pathogenesis and therapy of psoriasis |
Q37831326 | Personalizing dermatology: the future of genomic expression profiling to individualize dermatologic therapy |
Q34548462 | Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris |
Q37358800 | Prolactin and the skin: a dermatological perspective on an ancient pleiotropic peptide hormone |
Q24598008 | Promising new treatments for psoriasis |
Q35045850 | Psoriasis and Metabolic Syndrome--scientific evidence and therapeutic implications |
Q37743164 | Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions |
Q37607422 | Psoriasis comorbidities |
Q84927761 | Psoriasis during interferon beta treatment for multiple sclerosis |
Q92650604 | Psoriasis: Obesity and Fatty Acids |
Q35006118 | Psoriasis: crucial role of LXR-alpha RNomics |
Q36917184 | Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research |
Q41821146 | Psoriasis: female skin changes in various hormonal stages throughout life--puberty, pregnancy, and menopause |
Q37987880 | Role of IL-17 in psoriasis and psoriatic arthritis |
Q38458004 | Role of IL-17 in the pathogenesis of psoriatic arthritis and axial spondyloarthritis |
Q64318992 | Serum Concentrations of Interferon Gamma (IFN-γ) in Patients with Psoriasis: Correlation with Clinical Type and Severity of the Disease |
Q54273992 | Serum adiponectin and leptin levels in psoriatic patients according to topical treatment. |
Q50048507 | Serum levels of psoriasin (S100A7) and koebnerisin (S100A15) as potential markers of atherosclerosis in patients with psoriasis |
Q80506488 | Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype |
Q38056160 | The association between psoriasis and dyslipidaemia: a systematic review |
Q59323126 | The immunological and genetic aspects in psoriasis |
Q26752733 | The role of hormones in the pathogenesis of psoriasis vulgaris |
Q36500064 | Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis |
Q37081486 | Update on the natural history and systemic treatment of psoriasis |
Q54279129 | Vitamin D3 derivatives, alone or in combination with glucocorticoids, suppress streptococcal pyrogenic enterotoxin A-stimulated proliferation of peripheral blood mononuclear cells in patients with psoriasis. |
Q37756032 | Where do we stand with the genetics of psoriatic arthritis? |
Q48272707 | Withasteroid B from D. metel L. regulates immune responses by modulating the JAK/STAT pathway and the IL-17+ RORγt+ /IL-10+ FoxP3+ ratio. |
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