Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

scientific article

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2016.00477
P3181OpenCitations bibliographic resource ID2622355
P932PMC publication ID5100680
P698PubMed publication ID27877173

P50authorFrancesca BaroneQ48321559
Sanjiv A LutherQ51797070
Christopher D BuckleyQ87865766
Saba NayarQ109774294
P2093author name stringDavid H Gardner
Nathalie Steinthal
P2860cites workMarginal reticular cells: a stromal subset directly descended from the lymphoid tissue organizer.Q42234109
Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stromaQ42392661
Lymphotoxin-beta receptor signaling is required for the homeostatic control of HEV differentiation and functionQ42486404
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signalingQ42573173
Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cellsQ42753323
Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic isletsQ42936052
CD90(+) Stromal Cells are Non-Professional Innate Immune Effectors of the Human Colonic MucosaQ42964011
Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissuesQ44158648
From induced to programmed lymphoid tissues: the long road to preempt pathogensQ44441062
Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunityQ45018410
Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independentQ45857476
Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.Q46655434
Distinct transcriptional programs activated by interleukin-10 with or without lipopolysaccharide in dendritic cells: induction of the B cell-activating chemokine, CXC chemokine ligand 13.Q47578671
Lymph node genesis is induced by signaling through the lymphotoxin beta receptorQ47713223
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissuesQ47713235
Inflammation recapitulates the ontogeny of lymphoid stromal cellsQ47976120
Pulmonary lymphoid neogenesis in idiopathic pulmonary arterial hypertensionQ49041508
Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.Q49130159
Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.Q50144852
Synchrony of high endothelial venules and lymphatic vessels revealed by immunization.Q50476530
Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.Q50653103
CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.Q51013752
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Emerging Functions of RANKL in Lymphoid TissuesQ21131222
Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesisQ24300326
Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17AQ24597173
CXCR5⁺ T helper cells mediate protective immunity against tuberculosisQ24628780
Hepatic expression of secondary lymphoid chemokine (CCL21) promotes the development of portal-associated lymphoid tissue in chronic inflammatory liver diseaseQ24669792
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Tertiary Lymphoid Organs in Cancer TissuesQ26742168
Ectopic lymphoid follicles: inducible centres for generating antigen-specific immune responses within tissuesQ26778348
Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular CellsQ27302285
Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.Q27310763
Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKLQ27316867
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node FunctionalityQ27341894
Fibroblastic reticular cells: organization and regulation of the T lymphocyte life cycleQ27694402
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsQ27860460
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cellsQ27860620
Lymph node fibroblastic reticular cells in health and diseaseQ28087190
Requirement for RORgamma in thymocyte survival and lymphoid organ developmentQ28139666
A chemokine-driven positive feedback loop organizes lymphoid folliclesQ28142202
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17Q28213628
Podoplanin: emerging functions in development, the immune system, and cancerQ28275310
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxinQ28507630
Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responsesQ28510184
Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsivenessQ28510392
Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node developmentQ28585776
Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulationQ28585797
Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient miceQ28587099
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient miceQ28587819
Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytesQ28590628
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cellsQ29616148
Molecular antagonism and plasticity of regulatory and inflammatory T cell programsQ29619478
Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venulesQ30047232
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitectureQ30090178
Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β ReceptorsQ30279169
Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humansQ30475578
Fate mapping reveals origin and dynamics of lymph node follicular dendritic cellsQ30579711
Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell toleranceQ30579730
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- miceQ33399367
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synoviumQ33399862
Development and maturation of secondary lymphoid tissues.Q33652498
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditionsQ33794995
Dendritic cells produce CXCL13 and participate in the development of murine small intestine lymphoid tissuesQ33816393
Ontogeny of stromal organizer cells during lymph node development.Q33823116
Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin beta-receptor NF-kappaB signalingQ33869955
Inflammation, a prototype for organogenesis of the lymphopoietic/hematopoietic systemQ33898934
Fibroblast heterogeneity in the cancer woundQ33964324
Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironmentQ34019270
Follicular stromal cells and lymphocyte homing to follicles.Q34067358
TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cellsQ34080755
Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxideQ34081643
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cellsQ34082904
Diversity, topographic differentiation, and positional memory in human fibroblastsQ34190312
The development of inducible bronchus-associated lymphoid tissue depends on IL-17.Q34191942
Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in miceQ36005413
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarksQ36007057
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infectionQ36024206
IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organsQ36055624
Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugsQ36085027
CCL21 expression pattern of human secondary lymphoid organ stroma is conserved in inflammatory lesions with lymphoid neogenesis.Q36095617
Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammationQ36174679
Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.Q36180696
Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.Q36192967
Optical projection tomography reveals dynamics of HEV growth after immunization with protein plus CFA and features shared with HEVs in acute autoinflammatory lymphadenopathyQ36213800
Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes.Q36223887
Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 miceQ36253046
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodesQ36278300
Genetic polymorphism directs IL-6 expression in fibroblasts but not selected other cell types.Q36354844
Chronic inflammation caused by lymphotoxin is lymphoid neogenesisQ36366337
Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptorQ36369174
Splenic T zone development is B cell dependentQ36369671
Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted SulfotransferaseQ36370988
Lymphotoxin-alpha (LTalpha) supports development of splenic follicular structure that is required for IgG responsesQ36377326
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthmaQ36377337
B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion.Q36400576
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferationQ36403539
Generation of splenic follicular structure and B cell movement in tumor necrosis factor-deficient mice.Q36404217
Lymphoid organ development: from ontogeny to neogenesisQ36426808
Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2.Q36567149
Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and functionQ36630985
Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritisQ36633247
Keystones in lymph node developmentQ36633456
Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formationQ36694152
Development and function of the mammalian spleen.Q36709430
BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphomaQ36762885
Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrityQ36837719
Therapy of gastric mucosa-associated lymphoid tissue lymphomaQ36847291
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanomaQ36853440
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cellsQ36985100
Follicular dendritic cells emerge from ubiquitous perivascular precursorsQ36991851
Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity.Q37064773
Mesenchymal Cells of the Intestinal Lamina PropriaQ37125569
Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid StructuresQ37189681
The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritisQ37211275
B cells promote resistance to heterosubtypic strains of influenza via multiple mechanisms.Q37267195
Germinal center centroblasts transition to a centrocyte phenotype according to a timed program and depend on the dark zone for effective selection.Q37309590
Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunityQ37402415
Pivotal role of dermal IL-17-producing γδ T cells in skin inflammationQ34222410
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responsesQ34375200
B cell homeostasis and follicle confines are governed by fibroblastic reticular cellsQ34383642
Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblastsQ34383988
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleenQ34488105
Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cellsQ34501407
Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid.Q34568588
Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis.Q34586903
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretionQ34615273
TNFα-dependent development of lymphoid tissue in the absence of RORγt⁺ lymphoid tissue inducer cellsQ34690481
Development of secondary lymphoid organsQ34764895
The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodesQ34941714
Stromal cell contributions to the homeostasis and functionality of the immune system.Q34994909
Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease.Q35012792
Identification of a new stromal cell type involved in the regulation of inflamed B cell folliclesQ35017978
Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndromeQ35082778
Lymphotoxin plays a crucial role in the development and function of nasal-associated lymphoid tissue through regulation of chemokines and peripheral node addressinQ35083503
Organogenesis of lymphoid tissuesQ35096187
Deciphering the stromal and hematopoietic cell network of the adventitia from non-aneurysmal and aneurysmal human aortaQ35108490
A critical role for dendritic cells in the formation of lymphatic vessels within tertiary lymphoid structuresQ35108664
Circulating T follicular regulatory and helper cells have memory-like propertiesQ35145397
Foxp3+ follicular regulatory T cells control the germinal center response.Q35239023
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.Q35566574
Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytesQ35630052
Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictorsQ35637298
Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunologyQ35638915
Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centersQ35669109
Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid.Q35691047
Inflammation, Innate Immunity, and the Intestinal Stromal Cell Niche: Opportunities and ChallengesQ35754092
Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial PermeabilityQ35797634
Ectopic lymphoid neogenesis is strongly associated with activation of the IL-23 pathway in rheumatoid synovitisQ35834582
Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cellsQ35927606
Pulmonary expression of CXC chemokine ligand 13, CC chemokine ligand 19, and CC chemokine ligand 21 is essential for local immunity to influenzaQ35973395
Cellular interactions in lymph node developmentQ35990072
Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodesQ37475213
Role of the Lymphotoxin/LIGHT System in the Development and Maintenance of Reticular Networks and Vasculature in Lymphoid TissuesQ37576573
Lymphatic vessels and tertiary lymphoid organsQ37602241
New insights into the development of lymphoid tissuesQ37779724
Cellular and Molecular Requirements in Lymph Node and Peyer's Patch DevelopmentQ37783746
Stromal cell-immune cell interactionsQ37809072
Why does chronic inflammation persist: An unexpected role for fibroblastsQ37844776
Evolution of lymphoid tissuesQ38000791
Tertiary lymphoid organs in infection and autoimmunityQ38012568
Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.Q38025388
Intestinal stromal cells in mucosal immunity and homeostasis.Q38067055
Mesenchymal cell differentiation during lymph node organogenesisQ38068182
The role of non-hematopoietic stromal cells in the persistence of inflammationQ38075556
Insight into lymphoid tissue morphogenesis.Q38129702
Ectopic lymphoid-like structures in infection, cancer and autoimmunityQ38221815
T follicular helper cell differentiation, function, and roles in diseaseQ38264816
Tertiary lymphoid structures in cancer and beyondQ38274486
Stromal infrastructure of the lymph node and coordination of immunityQ38286890
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunityQ38408658
Stromal cells in chronic inflammation and tertiary lymphoid organ formationQ38415281
IL-17 increases cadherin-11 expression in a model of autoimmune experimental arthritis and in rheumatoid arthritisQ38471885
Immunological hallmarks of stromal cells in the tumour microenvironmentQ38608340
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCsQ38641655
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lungQ38939468
CLEC-2 is required for development and maintenance of lymph nodes.Q39675353
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.Q39804205
Organizer-like reticular stromal cell layer common to adult secondary lymphoid organsQ39926763
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagenQ39986041
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cellsQ40068378
Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-betaQ40168787
Generation of a synthetic lymphoid tissue-like organoid in miceQ40487229
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathwaysQ40696432
Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced NeuroinflammationQ40775503
Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells.Q40852544
Conduits mediate transport of low-molecular-weight antigen to lymph node folliclesQ41291427
T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T-cell depletionQ41400520
Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cellsQ41589815
BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.Q41740089
Lymph sacs are not required for the initiation of lymph node formationQ41985446
Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected miceQ42036256
Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation.Q42095379
Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organsQ42196937
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammationQ42202704
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.Q51984858
Presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes.Q52087999
Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization.Q52528591
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.Q52590127
Control of the T follicular helper-germinal center B-cell axis by CD8⁺ regulatory T cells limits atherosclerosis and tertiary lymphoid organ development.Q52656274
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma.Q52911127
Mycobacterium tuberculosis triggers formation of lymphoid structure in murine lungs.Q52928677
Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.Q53148065
Prenatal blockage of lymphotoxin beta receptor and TNF receptor p55 signaling cascade resulted in the acceleration of tissue genesis for isolated lymphoid follicles in the large intestine.Q53624871
Tissue-Specific Function of Lymph Node Fibroblastic Reticulum CellsQ57556772
Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granulomaQ58003719
Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndromeQ60548220
Ultrasonographic and MRI characterisation of the palindromic phase of rheumatoid arthritisQ60622647
Involvement of subchondral bone marrow in rheumatoid arthritis: Lymphoid neogenesis and in situ relationship to subchondral bone marrow osteoclast recruitmentQ60622664
CXCL13, CCL21, and CXCL12 Expression in Salivary Glands of Patients with Sjogren's Syndrome and MALT Lymphoma: Association with Reactive and Malignant Areas of Lymphoid OrganizationQ60810847
Activation-Induced Cytidine Deaminase Expression in Follicular Dendritic Cell Networks and Interfollicular Large B Cells Supports Functionality of Ectopic Lymphoid Neogenesis in Autoimmune Sialoadenitis and MALT Lymphoma in Sjogren's SyndromeQ60810867
Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndromeQ60810881
Systematic microanatomical analysis of CXCL13 and CCL21in situ production and progressive lymphoid organization in rheumatoid synovitisQ60810884
Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor therapy in rheumatoid arthritisQ60915160
RANKL Induces Organized Lymph Node Growth by Stromal Cell ProliferationQ61051808
Sustained interleukin‐6 signalling leads to the development of lymphoid organ‐like structures in the lungQ64377813
Fetal and neonatal development of human spleen: an immunohistological studyQ68154646
Role of lymphotoxin and the type I TNF receptor in the formation of germinal centersQ71095987
Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin-sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor I functionQ73419615
Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissueQ73588426
MAdCAM-1 expressed in chronic inflammatory liver disease supports mucosal lymphocyte adhesion to hepatic endothelium (MAdCAM-1 in chronic inflammatory liver disease)Q73851577
Priming of naive T cells inside tumors leads to eradication of established tumorsQ75221014
Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patchesQ78651212
Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organsQ79257160
Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid jointQ79765411
Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structureQ80171529
Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-betaQ80358435
CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritisQ81377156
Epidermal CCR6+ γδ T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitisQ85067559
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
tertiary lymphoid structureQ54928327
P304page(s)477
P577publication date2016-11-08
P1433published inFrontiers in ImmunologyQ27723748
P1476titleStromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation
P478volume7

Reverse relations

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