HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells

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HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.0020198
P3181OpenCitations bibliographic resource ID1492380
P932PMC publication ID449855
P698PubMed publication ID15252446
P5875ResearchGate publication ID8457899

P2093author name stringKyra Oswald-Richter
Derya Unutmaz
David W Haas
Mindy Leelawong
Mark S Sundrud
Nikki Shariat
Stacy M Grill
P2860cites workDisruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouseQ24290693
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndromeQ24626901
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetesQ28143530
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation timeQ29547822
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionQ29547852
Viral dynamics in human immunodeficiency virus type 1 infectionQ29547908
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfyQ29619109
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Q29619324
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 productionQ29619536
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndromeQ33404650
Regulatory T cells in autoimmmunity*.Q33904108
Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitroQ33942128
Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGNQ34010226
A history of prostate cancer treatmentQ34013878
T cell depletion in HIV-1 infection: how CD4+ T cells go out of stockQ34052457
CD25+CD4+ T cells contribute to the control of memory CD8+ T cellsQ34066063
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune diseaseQ34132578
Depletion of CD4+ T cells during immunization with nonviable Listeria monocytogenes causes enhanced CD8+ T cell-mediated protection against listeriosis.Q51024747
Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell DifferentiationQ52005548
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.Q52011695
T cell signaling mechanisms that regulate HIV-1 infection.Q52018818
Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.Q52247397
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.Q54139898
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
Twenty-first century Foxp3Q56987489
CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?Q59375800
IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In VivoQ60700622
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10Q73509865
Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone populationQ73740429
Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergicsQ74019442
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethalityQ78033315
Regulatory T cells in spontaneous autoimmune encephalomyelitisQ34448458
IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomenaQ34468346
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.Q34518941
CD4+ CD25+ suppressor T cells: more questions than answersQ34716304
CD4(+) regulatory T cells in autoimmunity and allergyQ34987296
Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cellsQ35104944
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasisQ35159540
Foxp3 and natural regulatory T cells: key to a cell lineage?Q35204514
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetesQ35978587
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytesQ36368207
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockadeQ36369151
CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infectionQ36370230
Distinct functional lineages of human V(alpha)24 natural killer T cellsQ36370354
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer stainingQ36370359
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responsesQ36371702
Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapyQ36376383
Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigensQ36954734
Human immunodeficiency virus type 1 spinoculation enhances infection through virus bindingQ39539552
Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytesQ40687886
Multifactorial nature of human immunodeficiency virus disease: implications for therapyQ40777913
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.Q40801370
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecificQ40910998
Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokinesQ41088030
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cellsQ41908906
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human bloodQ41973912
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral bloodQ41988688
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cellsQ42947524
Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responsesQ42947652
Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartmentQ47243986
Tracking the immunoregulatory mechanisms active during allograft toleranceQ49022949
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
P304page(s)E198
P577publication date2004-07-01
P1433published inPLOS BiologyQ1771695
P1476titleHIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
P478volume2

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cites work (P2860)
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Q40106774The role of nanotechnology in the treatment of viral infections.
Q36535760The role of virus-induced regulatory T cells in immunopathology
Q35847636Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells
Q83350829UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells

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