T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock

scientific article

T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1038/79724
P698PubMed publication ID11017098
P5875ResearchGate publication ID12306841

P2093author name stringMiedema F
Schuitemaker H
Hamann D
Hazenberg MD
P2860cites workReduced rate of disease development after HIV-2 infection as compared to HIV-1Q28237927
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremiaQ28254584
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of diseaseQ28267375
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionQ29547852
Viral dynamics in human immunodeficiency virus type 1 infectionQ29547908
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infectionQ29619738
Effect of HIV on thymic function before and after antiretroviral therapy in childrenQ33180147
Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissuesQ33652519
T cell dynamics in HIV-1 infection.Q33683207
Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infectionQ33793153
Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infectionQ33817504
Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues.Q33854488
The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infectionQ33904114
Altered representation of naive and memory CD8 T cell subsets in HIV-infected childrenQ34215632
CD8 naive T cell counts decrease progressively in HIV-infected adultsQ34215781
Thymic involution with ageing: obsolescence or good housekeeping?Q34410911
HLA haplotype A1 B8 DR3 as a risk factor for HIV-related diseaseQ34560245
In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell declineQ35015256
Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolutionQ36048710
Direct evidence for thymic function in adult humansQ36375219
Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapyQ36375293
Telomere length, telomerase activity, and replicative potential in HIV infection: analysis of CD4+ and CD8+ T cells from HIV-discordant monozygotic twinsQ36377040
Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection as measured by Ki-67 antigenQ36400677
T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cellsQ36557127
Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapyQ36974912
Factors influencing T-cell turnover in HIV-1-seropositive patientsQ37175631
Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humansQ37366743
High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection.Q37382323
Increased rates of CD4(+) and CD8(+) T lymphocyte turnover in simian immunodeficiency virus-infected macaquesQ37412108
Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV diseaseQ40049075
Lifespans of naive, memory and effector lymphocytesQ40832453
HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophagesQ40931545
Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.Q41557849
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.Q41611623
T cell turnover in HIV-1 diseaseQ41656290
Rapid CD4+ T-cell turnover in HIV-1 infection: a paradigm revisitedQ41701875
AIDS pathogenesis: a dynamic interaction between HIV and the immune systemQ41913909
Antigen-independent activation of naive and memory resting T cells by a cytokine combinationQ42942555
CD4+ and CD8+ T lymphocyte regeneration after anti-retroviral therapy in HIV-1-infected children and adult patientsQ44518380
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infectionQ44902494
Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapyQ45745478
Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolutionQ45745490
Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infectionQ45752981
Quantitation of human immunodeficiency virus type 1 in the blood of infected personsQ45844274
Effect of recent thymic emigrants on progression of HIV-1 diseaseQ45865760
Determinants of HIV disease progression: six-year longitudinal study in the Edinburgh haemophilia/HIV cohortQ45880593
Reduced naive and increased activated CD4 and CD8 cells in healthy adult Ethiopians compared with their Dutch counterpartsQ46721319
Limited CD4+ T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapyQ47852642
Normal telomere lengths in naive and memory CD4+ T cells in HIV type 1 infection: a mathematical interpretation.Q52032408
Early recovery of CD4+ T lymphocytes in children on highly active antiretroviral therapy. Dutch study group for children with HIV infections.Q52036600
Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation.Q52040570
Immunological and virological markers in individuals progressing from seroconversion to AIDS.Q52097479
Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.Q52247397
T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell TurnoverQ57204184
Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volumeQ57997617
Thymus volume correlates with the progression of vertical HIV infectionQ57997658
Changes in thymic function with age and during the treatment of HIV infectionQ59066353
T cell activation and disease severity in HIV infectionQ62068077
Programmed death of T cells in HIV-1 infectionQ67518695
Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapyQ72356532
T-cell homeostasis in HIV infection is neither failing nor blind: modified cell counts reflect an adaptive response of the hostQ73321259
HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapiesQ73321295
Reconstitution of lymphocyte subpopulations after paediatric bone marrow transplantationQ73446061
Diversity of the T-cell receptor BV repertoire in HIV-1-infected patients reflects the biphasic CD4+ T-cell repopulation kinetics during highly active antiretroviral therapyQ77754213
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
P304page(s)285-289
P577publication date2000-10-01
P1433published inNature ImmunologyQ1071725
P1476titleT cell depletion in HIV-1 infection: how CD4+ T cells go out of stock
P478volume1

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