CD4(+) regulatory T cells in autoimmunity and allergy

scientific article

CD4(+) regulatory T cells in autoimmunity and allergy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0952-7915(02)00408-9
P698PubMed publication ID12413528

P2093author name stringJuan J Lafaille
Maria A Curotto de Lafaille
P2860cites workDifferentiation of regulatory T cells 1 is induced by CD2 costimulationQ24291651
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivityQ24302386
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Tob is a negative regulator of activation that is expressed in anergic and quiescent T cellsQ28203889
B cells and professional APCs recruit regulatory T cells via CCL4Q28204573
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitisQ29619339
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 productionQ29619536
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoQ30080006
Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional studyQ30307035
Regulatory T cells overexpress a subset of Th2 gene transcriptsQ31035510
What is the role of regulatory T cells in transplantation tolerance?Q33745150
Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.Q34032006
The role of different subsets of T regulatory cells in controlling autoimmunityQ34096248
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Transcriptional mechanisms underlying lymphocyte tolerance.Q34135663
Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cellsQ34374601
CD4(+) regulatory T cellsQ34418015
Regulatory T cells in spontaneous autoimmune encephalomyelitisQ34448458
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
Identification of regulatory T cells in tolerated allograftsQ34524237
Interleukin 2 signaling is required for CD4(+) regulatory T cell functionQ34527240
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitisQ34719541
T-cell subsets in autoimmunityQ35604988
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cellsQ36369028
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.Q36370315
Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytesQ36376403
Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitisQ36401257
CD4(+) T cells prevent spontaneous experimental autoimmune encephalomyelitis in anti-myelin basic protein T cell receptor transgenic miceQ36401263
Role of interleukin 10 in specific immunotherapyQ37387064
Fingerprints of anergic T cellsQ38300517
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitusQ40581531
Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigenQ40701079
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells.Q40811244
A model for developmentally acquired thymus-dependent tolerance to central and peripheral antigensQ41326884
Anergic T cells as suppressor cells in vitroQ41461549
CD4+ T-cell subsets in autoimmunityQ41716697
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].Q41907086
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cellsQ41908906
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cellsQ42944333
Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient miceQ43407182
CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cellsQ43562885
To E or not to E? Can an IL-4-induced B cell choose between IgE and IgG4?Q44918734
Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humansQ45221904
A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral bloodQ46284741
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependencyQ47992795
Myelin protein expression in lymphoid tissues: implications for peripheral toleranceQ48363174
CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations.Q52165458
Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation toleranceQ56904417
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferationQ56904469
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cellsQ56904544
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic miceQ71641038
Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell developmentQ73311881
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10Q73509865
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptideQ73688337
Repertoire requirements of CD4+ T cells that prevent spontaneous autoimmune encephalomyelitisQ73756000
Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanismsQ73955062
Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cellQ74198800
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigenQ74286698
Origin of regulatory T cells with known specificity for antigenQ74381747
Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetesQ77192908
Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivoQ77342616
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
Control of immune pathology by regulatory T cellsQ77892048
CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient miceQ78022304
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)771-778
P577publication date2002-12-01
P1433published inCurrent Opinion in ImmunologyQ15752917
P1476titleCD4(+) regulatory T cells in autoimmunity and allergy
P478volume14

Reverse relations

cites work (P2860)
Q33829731A reduction of recipient regulatory T cells by cyclophosphamide contributes to an anti-tumor effect of nonmyeloablative allogeneic stem cell transplantation in mice
Q79780010Allergic sensitization and microbial load--a comparison between Finland and Russian Karelia
Q49924076An ex vivo ruminal ovine model to study the immediate immune response in the context of bacterial lipopolysaccharide
Q35936478An integrated view of suppressor T cell subsets in immunoregulation
Q28071408Atopy and autoimmune thyroid diseases: melatonin can be useful?
Q46057094Augmentation of regulatory T cells in allergic individuals by recombinant Der f 2 peptide with fungal immunomodulatory peptide fve.
Q80622205Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
Q29618394CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
Q83160035CD25+ T(reg) specifically suppress auto-Ab generation against pancreatic tissue autoantigens
Q36849492CD28-B7 interaction modulates short- and long-lived plasma cell function.
Q36223583CD4+CD25+-regulatory T cells from mouse to man.
Q36605447Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity
Q46155473Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo.
Q36150414Clinical application of human CD4+ CD25+ regulatory T cells for the treatment of inflammatory bowel diseases
Q34133590Control of homeostatic proliferation by regulatory T cells
Q33992511Cow's milk allergy: a complex disorder
Q37260860Cumulative environmental changes, skewed antigen exposure, and the increase of allergy
Q51052689Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus.
Q43977388Decreased FoxP3 gene expression in the nasal secretions from patients with allergic rhinitis
Q53561906Demonstration of low-regulatory CD25High+CD4+ and high-pro-inflammatory CD28-CD4+ T-Cell subsets in patients with ulcerative colitis: modified by selective granulocyte and monocyte adsorption apheresis.
Q80466965Downregulation of CD4+CD25+ regulatory T cells may underlie enhanced Th1 immunity caused by immunization with activated autologous T cells
Q57173908Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages
Q36676017Effect of bacillus Calmette-Guérin vaccination on CD4+Foxp3+ T cells during acquired immune response to Mycobacterium tuberculosis infection
Q51744632Effect of desensitization in solid organ transplant recipients depends on some cytokines genes polymorphism.
Q58196727Evaluation of Natural Regulatory T Cells in Subjects with Selective IgA Deficiency: From Senior Idea to Novel Opportunities
Q49427525Exon 3 mutations of CTNNB1 drive tumorigenesis: a review
Q42276749Expression analysis of Foxp3 in T cells from bovine leukemia virus infected cattle
Q54236063Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus.
Q35829151Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimeras
Q35742927Glucocorticoids increase CD4CD25 cell percentage and Foxp3 expression in patients with multiple sclerosis.
Q33867263Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity
Q24802813HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
Q42969634High proportions of FOXP3(+) CD25(high) T cells in neonates are positively associated with allergic sensitization later in childhood
Q62801176Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10
Q35211699Hypothesis: dysregulation of immunologic balance resulting from hygiene and socioeconomic factors may influence the epidemiology and cause of glomerulonephritis worldwide
Q40164065IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy
Q36403560IL-18-induced CD83+CCR7+ NK helper cells
Q64903098Immune reaction by cytoreductive prostatectomy.
Q35083879Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis
Q84923108Impaired function of regulatory T cells in cord blood of children of allergic mothers
Q36399048In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
Q33471458Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression
Q35835456Inhibition of experimental asthma by indoleamine 2,3-dioxygenase
Q35849633Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma
Q35568027Keeping hopes high
Q35810098LYRA, a webserver for lymphocyte receptor structural modeling
Q48858723Lack of association between TESPA1 gene polymorphisms (rs1801876, rs2171497, rs4758994, and rs997173) and ankylosing spondylitis in a Chinese population
Q34103249Malignant B cells induce the conversion of CD4+CD25- T cells to regulatory T cells in B-cell non-Hodgkin lymphoma
Q36263707Markers to measure immunomodulation in human nutrition intervention studies.
Q28272127Modulation of the human cytokine response by interferon lambda-1 (IFN-lambda1/IL-29)
Q33617780Modulatory role of regulatory T cells in a murine model of severe equine asthma
Q36541003New aspects on inflammation in allergic diseases.
Q34477650OX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunity
Q33840440Oral tolerance in the absence of naturally occurring Tregs
Q44890967Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study
Q38502556Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis
Q46401511Putative regulatory T cells are impaired in cord blood from neonates with hereditary allergy risk
Q45859587Reduced function of CD4+25+ regulatory T cell fraction in silicosis patients
Q42667085Regulatory T cell expansion and immune activation during untreated HIV type 1 infection are associated with disease progression
Q35582278Regulatory T cells accumulate in the lung allergic inflammation and efficiently suppress T-cell proliferation but not Th2 cytokine production
Q36079905Regulatory T cells and autoimmune disease
Q36419022Regulatory T cells in lupus
Q33236315Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
Q45877596Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?
Q35628016Role of T cell co-stimulation in murine models of allergic asthma
Q36580331Specialized role of migratory dendritic cells in peripheral tolerance induction
Q45914983Suppression of Th1- and Th2-type immune responses in infant mouse spleen after prenatal and postnatal exposure to low-level toluene and peptidoglycan.
Q37084875T-cell activation through immunological synapses and kinapses
Q92277085The Pungent and Hot Chinese Herbs Cause Heat Syndrome in Rats by Affecting the Regulatory T Cells
Q24816497The allergy adjuvant effect of particles - genetic factors influence antibody and cytokine responses
Q36218421The development and function of memory regulatory T cells after acute viral infections
Q34922215The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation
Q51765029The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease.
Q36232960The immunopathogenesis of cow's milk protein allergy (CMPA).
Q37037449The role of CD4+CD25+ T regulatory cells in autoimmune diseases
Q36752196The role of natural regulatory T cells in infection
Q35685189The role of regulatory T cells in allergy
Q37409192Therapeutic efficacy of soluble receptor activator of nuclear factor-kappa B-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma
Q79274214Timing of IFN-β Exposure during Human Dendritic Cell Maturation and Naive Th Cell Stimulation Has Contrasting Effects on Th1 Subset Generation: A Role for IFN-β-Mediated Regulation of IL-12 Family Cytokines and IL-18 in Naive Th Cell Differentiation
Q36942513Tolerance and autoimmunity: lessons at the bedside of primary immunodeficiencies
Q37420965Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands
Q36466223Translating the concept of suppressor/regulatory T cells to clinical applications
Q41519827Treg/Th17 cell balance and phytohaemagglutinin activation of T lymphocytes in peripheral blood of systemic sclerosis patients
Q36381918Tumor-infiltrating T lymphocytes: friends or foes?
Q45871925Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
Q38888149Understanding the Regulatory Roles of Natural Killer T Cells in Rheumatoid Arthritis: T Helper Cell Differentiation Dependent or Independent?
Q36107768Unraveling innate immunity using large scale N-ethyl-N-nitrosourea mutagenesis
Q30498716Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
Q28282226World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines