Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity.

scientific article published on August 2006

Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.0105-2896.2006.00422.X
P698PubMed publication ID16903923
P5875ResearchGate publication ID6883342

P50authorRalph SteinmanQ105494
Kayo InabaQ20982982
Kristin V TarbellQ56250472
P2093author name stringSayuri Yamazaki
P2860cites workAntigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivityQ24302386
Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T CellsQ58131166
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cellsQ24306205
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cellsQ24538658
Essential role for CD103 in the T cell-mediated regulation of experimental colitisQ24646106
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammationQ24676080
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Foxp3 programs the development and function of CD4+CD25+ regulatory T cellsQ27860714
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetesQ28143530
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymusQ28268867
Regulatory T cell lineage specification by the forkhead transcription factor foxp3Q28510328
An essential role for Scurfin in CD4+CD25+ T regulatory cellsQ29618395
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-selfQ29619194
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionQ29619536
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic miceQ30498716
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivoQ33236315
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammationQ33876035
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporterQ33936032
A history of prostate cancer treatmentQ34013878
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptorQ34116317
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cellsQ34189120
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.Q34269503
Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reactionQ34479579
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.Q34509694
CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host diseaseQ34525987
Interleukin 2 signaling is required for CD4(+) regulatory T cell functionQ34527240
Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.Q34529123
In vivo instruction of suppressor commitment in naive T cellsQ34548023
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.Q34554035
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cellsQ34556464
Regulatory T cells in transplantation toleranceQ35092535
Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cellsQ35867877
Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cellsQ35971446
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetesQ35978587
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cellsQ36061019
Natural regulatory T cells in infectious diseaseQ36078051
Regulatory T cells and intestinal homeostasisQ36079900
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockadeQ36369151
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
CD4+ CD25+ regulatory T cells control T helper cell type 1 responses to foreign antigens induced by mature dendritic cells in vivoQ36371316
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cellsQ36371345
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responsesQ36376333
The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunityQ36392364
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.Q36399104
Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cellsQ36399149
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal periodQ36402733
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cellsQ36402737
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralizationQ36402763
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.Q36403529
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferationQ36403539
Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytesQ40530227
Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.Q40565739
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR culturesQ40576782
Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo.Q40643930
Dendritic cells crossprime allo-specific self-restricted CD4(+) T cells after coculture with dead allogeneic cellsQ40724028
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.Q40801370
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecificQ40910998
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human bloodQ41973912
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive stateQ42466421
Regulatory T-cell therapy: is it ready for the clinic?Q43513695
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantationQ44408941
Modulation of tryptophan catabolism by regulatory T cells.Q44632333
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cellsQ45878833
Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivityQ46061458
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells.Q46499903
Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cellsQ47240621
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor functionQ47579310
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetesQ47667692
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.Q47726082
Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cellsQ47810559
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cellsQ50095546
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejectionQ50796687
CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cellsQ51991426
Toll-dependent control mechanisms of CD4 T cell activationQ51996404
Homing to suppress: address codes for Treg migrationQ53652321
Cutting edge: CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitisQ53671891
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cellsQ53883439
P921main subjectdendritic cellQ506253
P304page(s)314-329
P577publication date2006-08-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inImmunological ReviewsQ15724582
P1476titleDendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity
P478volume212

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