Human regulatory T cells: a unique, stable thymic subset or a reversible peripheral state of differentiation?

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Human regulatory T cells: a unique, stable thymic subset or a reversible peripheral state of differentiation? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IMLET.2007.08.012
P932PMC publication ID2095117
P698PubMed publication ID17945352
P5875ResearchGate publication ID5900992

P50authorNitin J KarandikarQ56285632
P2093author name stringVinodh Pillai
P2860cites workFOXP3 controls regulatory T cell function through cooperation with NFATQ24298179
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressorQ24300325
Foxp3 occupancy and regulation of key target genes during T-cell stimulationQ24623384
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cellsQ24645614
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infectionQ27482577
Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4Q28204758
Recombinant Ig-like transcript 3-Fc modulates T cell responses via induction of Th anergy and differentiation of CD8+ T suppressor cellsQ28298596
Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylationQ28587503
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cellsQ29618394
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-selfQ29619194
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412Q29622893
Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3Q33772149
De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cellsQ33932462
Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferationQ33993967
Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.Q53654834
Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humansQ54645452
Can super-antibody drugs be tamed?Q56674040
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinomaQ56904280
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferationQ56904469
Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHDQ57252628
FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent MechanismQ58123220
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cellsQ58234949
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell levelQ60311694
Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulationQ80097552
From vanilla to 28 flavors: multiple varieties of T regulatory cellsQ80141724
Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-betaQ80358435
A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-betaQ80427911
Regulatory/suppressor T cells in health and diseaseQ80806146
Inducing and expanding regulatory T cell populations by foreign antigenQ81392563
CD28 superagonists put a break on autoimmunity by preferentially activating CD4+CD25+ regulatory T cellsQ81596148
Transient accumulation of human mature thymocytes and regulatory T cells with CD28 superagonist in "human immune system" Rag2(-/-)gammac(-/-) miceQ82715228
Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosisQ83367385
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosisQ34311395
Regulatory T cells in cancerQ34550248
A role for Dicer in immune regulationQ34571997
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell developmentQ34597933
Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosisQ34789216
Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivoQ35009480
Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravisQ35740840
Transient regulatory T-cells: a state attained by all activated human T-cells.Q35792962
Mechanisms of immunotherapy.Q35811876
Functional avidity directs T-cell fate in autoreactive CD4+ T cellsQ35848366
CD4+ Tregs and immune controlQ35936484
Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotypeQ36059631
The role of self-peptides in the development of CD4+ CD25+ regulatory T cellsQ36070689
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.Q36078042
Mechanisms of suppression by suppressor T cellsQ36078047
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.Q36189566
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cellsQ36228688
Imbalance of regulatory T cells in human autoimmune diseasesQ36395703
Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type IIQ36399471
FOXP3: of mice and men.Q36427333
Treg control of antimicrobial T cell responsesQ36450013
Regulatory T cells in human disease and their potential for therapeutic manipulationQ36455974
The regulation of allergy and asthmaQ36563540
Regulatory T cells in virus infectionsQ36563550
Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity.Q36563563
The dynamic co-evolution of memory and regulatory CD4+ T cells in the peripheryQ36743559
Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigensQ36954734
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.Q38305613
The Hermaphrocyte: A Suppressor-Helper T CellQ39159049
Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infectionQ39571557
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine productionQ40165347
Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.Q40565739
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ TregsQ42181372
An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.Q43636357
Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivityQ47265853
Immunology. Considering therapeutic antibodiesQ51158284
P433issue1
P304page(s)9-15
P577publication date2007-09-29
P13046publication type of scholarly workreview articleQ7318358
P1433published inimmunology LettersQ15766068
P1476titleHuman regulatory T cells: a unique, stable thymic subset or a reversible peripheral state of differentiation?
P478volume114