review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1020329526 |
P356 | DOI | 10.1038/NI1179 |
P698 | PubMed publication ID | 15785758 |
P5875 | ResearchGate publication ID | 7949360 |
P50 | author | Alexander Rudensky | Q21012878 |
P2093 | author name string | Jason D Fontenot | |
P2860 | cites work | Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse | Q24290693 |
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation | Q24291515 | ||
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells | Q24306205 | ||
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome | Q24626901 | ||
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells | Q24645614 | ||
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 | Q24672849 | ||
Control of regulatory T cell development by the transcription factor Foxp3 | Q27860489 | ||
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 | ||
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes | Q28143530 | ||
The amount of scurfin protein determines peripheral T cell number and responsiveness | Q28504592 | ||
Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes | Q28509666 | ||
Regulatory T cell lineage specification by the forkhead transcription factor foxp3 | Q28510328 | ||
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7 | Q28591451 | ||
An essential role for Scurfin in CD4+CD25+ T regulatory cells | Q29618395 | ||
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy | Q29619109 | ||
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self | Q29619194 | ||
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 | Q29619324 | ||
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production | Q29619536 | ||
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses | Q29619908 | ||
Selecting and maintaining a diverse T-cell repertoire | Q33783983 | ||
The third function of the thymus. | Q33826591 | ||
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation | Q33876035 | ||
Regulatory T cells in autoimmmunity*. | Q33904108 | ||
Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype | Q34065191 | ||
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance | Q34111451 | ||
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor | Q34116317 | ||
Interleukin 2 signaling is required for CD4(+) regulatory T cell function | Q34527240 | ||
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function | Q34550108 | ||
Human T regulatory cells can use the perforin pathway to cause autologous target cell death | Q34551876 | ||
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. | Q34554035 | ||
Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice | Q34705919 | ||
CD4+ CD25+ suppressor T cells: more questions than answers | Q34716304 | ||
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis | Q35159540 | ||
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro | Q35171080 | ||
Development and function of CD25+CD4+ regulatory T cells | Q35692191 | ||
Tolerance, not immunity, crucially depends on IL-2. | Q35877199 | ||
Self-representation in the thymus: an extended view | Q35877206 | ||
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes | Q35978587 | ||
Mechanisms of suppression by suppressor T cells | Q36078047 | ||
The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology | Q36176101 | ||
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation | Q36367099 | ||
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells | Q36369536 | ||
T cell regulation as a side effect of homeostasis and competition | Q36370619 | ||
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness | Q36370807 | ||
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo | Q36371283 | ||
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. | Q36371658 | ||
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes | Q36399048 | ||
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. | Q36399562 | ||
Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis | Q36401257 | ||
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease | Q36672085 | ||
Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation | Q37358144 | ||
Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education | Q37537286 | ||
Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells | Q37569057 | ||
Do suppressor T cells exist? | Q39485474 | ||
Suppressor Cells and Immunoregulation | Q40119140 | ||
Lck activity controls CD4/CD8 T cell lineage commitment. | Q41729181 | ||
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state | Q42466421 | ||
Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function | Q46468450 | ||
Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25- T cells | Q47240613 | ||
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function | Q47579310 | ||
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. | Q47726082 | ||
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency | Q47992795 | ||
Peptide specificity of thymic selection of CD4+CD25+ T cells. | Q51058071 | ||
Mature T cells depend on signaling through the IKK complex. | Q52005562 | ||
CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations. | Q52165458 | ||
Allergy and Immunology | Q56019729 | ||
Cutting Edge: TGF- Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4+CD25+ T Cells | Q58131166 | ||
TGF regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo | Q58131190 | ||
Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium | Q59652622 | ||
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice | Q71641038 | ||
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10 | Q73509865 | ||
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide | Q73688337 | ||
Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells | Q74137391 | ||
Origin of regulatory T cells with known specificity for antigen | Q74381747 | ||
T cell regulation: a special job or everyone's responsibility? | Q74433979 | ||
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2 | Q74660381 | ||
Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo | Q77342616 | ||
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals | Q77704341 | ||
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression | Q77995835 | ||
Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity | Q78701749 | ||
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors | Q80444910 | ||
CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion | Q81111400 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 331-337 | |
P577 | publication date | 2005-04-01 | |
P1433 | published in | Nature Immunology | Q1071725 |
P1476 | title | A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. | |
P478 | volume | 6 |