scholarly article | Q13442814 |
P356 | DOI | 10.1093/TOXSCI/KFQ346 |
P953 | full work available at URL | https://academic.oup.com/toxsci/article-pdf/120/suppl_1/S238/4586743/kfq346.pdf |
P698 | PubMed publication ID | 21097995 |
P5875 | ResearchGate publication ID | 49629167 |
P50 | author | David A Basketter | Q90845405 |
P2093 | author name string | G. Frank Gerberick | |
Ian Kimber | |||
Cindy A. Ryan | |||
Rebecca J. Dearman | |||
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Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals | Q47279998 | ||
A tier approach for evaluating the respiratory allergenicity of low molecular weight chemicals | Q47420735 | ||
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A close-up view of migrating Langerhans cells in the skin. | Q49023130 | ||
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Some active areas of DC research and their medical potential | Q51792965 | ||
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An ATS/ERS report: 100 key questions and needs in occupational asthma. | Q53259397 | ||
B220 analysis with the local lymph node assay: proposal for a more flexible prediction model. | Q53569356 | ||
Inconsistencies between cytokine profiles, antibody responses, and respiratory hyperresponsiveness following dermal exposure to isocyanates. | Q53589788 | ||
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Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions | Q57275421 | ||
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Diversity of cytokine synthesis and function of mouse CD4+ T cells | Q36539209 | ||
Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity | Q36613524 | ||
The evolving function of Langerhans cells in adaptive skin immunity | Q36627481 | ||
Clinical and immunologic evaluation of trimellitic anhydride-and phthalic anhydride-exposed workers using a questionnaire with comparative analysis of enzyme-linked immunosorbent and radioimmunoassay studies | Q36645066 | ||
Dermal dendritic cells, and not Langerhans cells, play an essential role in inducing an immune response | Q36690927 | ||
Screening petrochemicals for contact hypersensitivity potential: a comparison of the murine local lymph node assay with guinea pig and human test data | Q36729082 | ||
Early molecular events in the induction phase of contact sensitivity | Q36837916 | ||
Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity | Q36853445 | ||
The local lymph node assay and the assessment of relative potency: status of validation | Q36879552 | ||
DC ablation in mice: promises, pitfalls, and challenges | Q36983300 | ||
Respiratory sensitization and allergy: current research approaches and needs | Q37006799 | ||
Dendritic cells and T cells in the regulation of cutaneous immunity | Q37045247 | ||
Chemical respiratory allergy and occupational asthma: what are the key areas of uncertainty? | Q37094750 | ||
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Workshop overview. Identification of respiratory allergens | Q46611052 | ||
Expression analysis of immune-related genes in CD34(+) progenitor-derived dendritic cells after exposure to the chemical contact allergen DNCB. | Q46672295 | ||
Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT). | Q46699801 | ||
Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L. | Q46701571 | ||
Skin sensitization: reaction mechanistic applicability domains for structure-activity relationships | Q46707312 | ||
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The role of the skin in the development of chemical respiratory hypersensitivity | Q41035765 | ||
Evaluation of the capacity of dendritic cells derived from cord blood CD34+ precursors to present haptens to unsensitized autologous T cells in vitro | Q41051642 | ||
The expanding universe of T-cell subsets: Th1, Th2 and more. | Q41120396 | ||
The local lymph node assay: status of validation | Q41333570 | ||
Acute ablation of Langerhans cells enhances skin immune responses | Q41906344 | ||
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In vitro primary sensitization of hapten-specific T cells by cultured human epidermal Langerhans cells--a screening predictive assay for contact sensitizers | Q42555051 | ||
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Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells | Q42830424 | ||
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Allergen-induced changes in interleukin 1 beta (IL-1 beta) mRNA expression by human blood-derived dendritic cells: inter-individual differences and relevance for sensitization testing | Q43565720 | ||
Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans | Q43572227 | ||
Glutathione S-transferase genotypes and allergic responses to diisocyanate exposure | Q43686372 | ||
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Cytokine profiling for chemical sensitizers: application of the ribonuclease protection assay and effect of dose | Q43924948 | ||
Respiratory hypersensitivity to trimellitic anhydride in Brown Norway rats: a comparison of endpoints | Q43938388 | ||
N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk | Q43943535 | ||
Application of a weight of evidence approach to assessing discordant sensitisation datasets: implications for REACH. | Q43969516 | ||
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates | Q43982684 | ||
Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses | Q44078559 | ||
Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay | Q44085269 | ||
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides | Q44159868 | ||
Cytokine production induced by low-molecular-weight chemicals as a function of the stimulation index in a modified local lymph node assay: an approach to discriminate contact sensitizers from respiratory sensitizers | Q44189128 | ||
Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses | Q44207543 | ||
The murine local lymph node assay: results of an inter-laboratory trial | Q44254376 | ||
Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation | Q44438856 | ||
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells | Q44517145 | ||
Methods for the identification of chemical respiratory allergens in rodents: comparisons of cytokine profiling with induced changes in serum IgE. | Q44528192 | ||
Sensitisation of guinea pigs by inhalation exposure to low molecular weight chemicals | Q44583749 | ||
Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen | Q44862653 | ||
A murine local lymph node assay for the identification of contact allergens. Assay development and results of an initial validation study | Q44933209 | ||
Development of a peptide reactivity assay for screening contact allergens | Q44978791 | ||
Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarization | Q45273243 | ||
Electrophilic reaction chemistry of low molecular weight respiratory sensitizers. | Q45926750 | ||
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe. | Q45929088 | ||
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens. | Q46034802 | ||
Reconstruction of three-dimensional human skin model composed of dendritic cells, keratinocytes and fibroblasts utilizing a handy scaffold of collagen vitrigel membrane | Q46176346 | ||
Dermal contact with toluene diisocyanate (TDI) produces respiratory tract hypersensitivity in guinea pigs | Q46189525 | ||
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response | Q46236599 | ||
Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation | Q46321032 | ||
The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test | Q46321126 | ||
Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations | Q46442621 | ||
Multivariate QSAR analysis of a skin sensitization database | Q46506019 | ||
Identification of contact and respiratory sensitizers using flow cytometry | Q46515196 | ||
Impact of cutaneous IL-10 on resident epidermal Langerhans' cells and the development of polarized immune responses | Q46561857 | ||
From innate to adaptive immune responses in contact hypersensitivity | Q37205744 | ||
Insights into Langerhans cell function from Langerhans cell ablation models | Q37268972 | ||
The development and function of regulatory T cells | Q37274250 | ||
The IL-17 cytokine family and their role in allergic inflammation | Q37285279 | ||
Nine lives: plasticity among T helper cell subsets | Q37292800 | ||
Dendritic cells: biology of the skin | Q37363179 | ||
Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound | Q37397784 | ||
Skin immune surveillance by T cells--a new order? | Q37445293 | ||
Molecular mechanism and function of CD40/CD40L engagement in the immune system. | Q37474929 | ||
Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells | Q37500619 | ||
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system | Q37555597 | ||
Chemical allergens--what are the issues? | Q37568230 | ||
The role of T helper subsets in autoimmunity and allergy | Q37580545 | ||
Potency values from the local lymph node assay: application to classification, labelling and risk assessment | Q37592650 | ||
The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers. | Q37600564 | ||
Effector and regulatory mechanisms in allergic contact dermatitis. | Q37617470 | ||
Non-animal sensitization testing: state-of-the-art | Q37697804 | ||
Revisiting the tolerogenicity of epidermal Langerhans cells | Q37704952 | ||
Langerhans cells: critical regulators of skin immunity? | Q37721150 | ||
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c | Q38491447 | ||
Antigen-presenting cells in the induction of contact hypersensitivity in mice: evidence that Langerhans cells are sufficient but not required | Q38516917 | ||
Immunotoxicologic evaluation of the respiratory system: animal models for immediate- and delayed-onset pulmonary hypersensitivity | Q39494843 | ||
Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes | Q39667090 | ||
Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds. | Q39690057 | ||
Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro. | Q39724841 | ||
Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans cells | Q39781292 | ||
Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1. | Q39854399 | ||
Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals. | Q39865611 | ||
The Langerhans cell controversy: are they immunostimulatory or immunoregulatory cells of the skin immune system? | Q39882251 | ||
HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway. | Q39912388 | ||
Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH. | Q40003682 | ||
Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro. | Q40211645 | ||
A future approach to measuring relative skin sensitising potency: a proposal | Q40316400 | ||
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT. | Q40342048 | ||
The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers. | Q40394149 | ||
Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation. | Q40447298 | ||
Classification of contact allergens according to potency: proposals | Q40555466 | ||
Respiratory allergy: hazard identification and risk assessment | Q40644918 | ||
A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel | Q40646680 | ||
Evaluation of the skin sensitization potential of chemicals using expression of co-stimulatory molecules, CD54 and CD86, on the naive THP-1 cell line | Q40662190 | ||
Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers. | Q40691251 | ||
P407 | language of work or name | English | Q1860 |
P304 | page(s) | S238-68 | |
P577 | publication date | 2010-11-22 | |
P1433 | published in | Toxicological Sciences | Q2446966 |
P1476 | title | Chemical allergy: translating biology into hazard characterization | |
P478 | volume | 120 Suppl 1 |
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