| scholarly article | Q13442814 |
| P50 | author | Juri Rappsilber | Q28324182 |
| P2093 | author name string | Matthias Mann | |
| Anastasia Wyce | |||
| Gideon Dreyfuss | |||
| Sergey Paushkin | |||
| Westley J Friesen | |||
| Linda Abel | |||
| P2860 | cites work | Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs | Q22008487 |
| A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing | Q22008514 | ||
| Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems | Q22010941 | ||
| Identification and characterization of a spinal muscular atrophy-determining gene | Q29547495 | ||
| Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry | Q29619562 | ||
| A cell system with targeted disruption of the SMN gene: functional conservation of the SMN protein and dependence of Gemin2 on SMN. | Q30976876 | ||
| Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin | Q31003752 | ||
| Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). | Q33905442 | ||
| Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription | Q33938819 | ||
| SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins. | Q35641208 | ||
| Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos | Q36578997 | ||
| Functions of U-snRNPs | Q37854929 | ||
| Characterization of the Schizosaccharomyces pombe orthologue of the human survival motor neuron (SMN) protein | Q38313541 | ||
| The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p, share structural and functional similarity with the spinal muscular atrophy-associated proteins SMN and SIP1. | Q38313544 | ||
| PRMT3 is a distinct member of the protein arginine N-methyltransferase family. Conferral of substrate specificity by a zinc-finger domain. | Q40863473 | ||
| G protein heterodimers: new structures propel new questions | Q40948230 | ||
| When is a deletion not a deletion? When it is converted | Q43105061 | ||
| The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability. | Q47068856 | ||
| Characterization of pICln phosphorylation state and a pICln-associated protein kinase | Q47864411 | ||
| Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit | Q48058003 | ||
| PRMT5 (Janus Kinase-binding Protein 1) Catalyzes the Formation of Symmetric Dimethylarginine Residues in Proteins | Q56227906 | ||
| Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli | Q22253358 | ||
| Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins | Q24312051 | ||
| The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins | Q24316085 | ||
| The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis | Q24316121 | ||
| A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor | Q24319127 | ||
| Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain | Q24336296 | ||
| pICln inhibits snRNP biogenesis by binding core spliceosomal proteins | Q24517638 | ||
| Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure | Q24540360 | ||
| The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins | Q24548244 | ||
| The Sm domain is an ancient RNA-binding motif with oligo(U) specificity | Q24618608 | ||
| A nuclear localization domain in the hnRNP A1 protein | Q24672627 | ||
| A functional interaction between the survival motor neuron complex and RNA polymerase II | Q24674951 | ||
| Crystal structure of a heptameric Sm-like protein complex from archaea: implications for the structure and evolution of snRNPs | Q27632475 | ||
| Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs | Q27639794 | ||
| The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2 | Q27732195 | ||
| The 2.0 A crystal structure of a heterotrimeric G protein | Q27732250 | ||
| Crystal structure of a G-protein beta gamma dimer at 2.1A resolution | Q27732270 | ||
| The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity | Q27931859 | ||
| Arginine methylation facilitates the nuclear export of hnRNP proteins | Q27931932 | ||
| Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy | Q28137718 | ||
| Regulation of transcription by a protein methyltransferase | Q28138085 | ||
| The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies | Q28140527 | ||
| Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family | Q28142367 | ||
| The WD repeat: a common architecture for diverse functions | Q28143827 | ||
| Spliceosomal UsnRNP biogenesis, structure and function | Q28188106 | ||
| SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets | Q28199238 | ||
| The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1 | Q28213183 | ||
| Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin | Q28247942 | ||
| Spinal muscular atrophy | Q28251310 | ||
| Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cells | Q28263029 | ||
| pICln binds to a mammalian homolog of a yeast protein involved in regulation of cell morphology | Q28268574 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | identical protein binding | Q14762994 |
| methylosome | Q21106317 | ||
| Protein arginine methyltransferase 5 | Q21130994 | ||
| P304 | page(s) | 8243-7 | |
| P577 | publication date | 2002-03-08 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | A novel WD repeat protein component of the methylosome binds Sm proteins | |
| P478 | volume | 277 |
| Q107602794 | Methylosome |
| Q107514937 | PRMT5 methylosome complex, CLNS1A variant |
| Q86996667 | 3 Diverse roles of protein arginine methyltransferases |
| Q35040908 | A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage |
| Q37294322 | Androgen receptor coactivator p44/Mep50 in breast cancer growth and invasion |
| Q34002244 | Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. |
| Q34279382 | Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing |
| Q33572966 | Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization |
| Q33707074 | Arginine methylation of vasa protein is conserved across phyla |
| Q55093730 | CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription. |
| Q40635200 | Cell swelling stimulates cytosol to membrane transposition of ICln. |
| Q37600751 | Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors. |
| Q37217217 | Cis-active RNA elements (CREs) and picornavirus RNA replication |
| Q38411717 | Control of the DNA methylation system component MBD2 by protein arginine methylation |
| Q42006607 | Conversion of VPg into VPgpUpUOH before and during poliovirus negative-strand RNA synthesis |
| Q34463476 | CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex |
| Q47445776 | Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate |
| Q27674576 | Crystal structure of the human PRMT5:MEP50 complex |
| Q28593215 | Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer |
| Q37628111 | E2F and GATA switches turn off WD repeat domain 77 expression in differentiating cells |
| Q39552092 | Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice |
| Q42628253 | Evolutionarily divergent type II protein arginine methyltransferase in Trypanosoma brucei |
| Q34056207 | Expression and function of androgen receptor coactivator p44/Mep50/WDR77 in ovarian cancer |
| Q87045773 | Expression of mep50 in adult and embryos of medaka fish (Oryzias latipes) |
| Q33421929 | Function and pathological implications of exon junction complex factor Y14 |
| Q28115894 | Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis |
| Q24301969 | Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly |
| Q24306053 | Gemin8 is required for the architecture and function of the survival motor neuron complex |
| Q35351891 | Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase |
| Q47624813 | Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1. |
| Q30156902 | Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication |
| Q24312875 | Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells |
| Q28251752 | ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4 |
| Q24299793 | Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex |
| Q28304227 | Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation |
| Q34107266 | Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5 |
| Q38740496 | Inhibitors of Protein Methyltransferases and Demethylases. |
| Q38255119 | Insights into the U1 small nuclear ribonucleoprotein complex superfamily |
| Q39593309 | JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation |
| Q56980693 | LKB1 regulates PRMT5 activity in breast cancer |
| Q35195403 | Lessons for inductive germline determination |
| Q36172838 | Loss of the androgen receptor cofactor p44/WDR77 induces astrogliosis |
| Q90013973 | Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges |
| Q33695616 | Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs |
| Q41999930 | MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties. |
| Q61446372 | MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex |
| Q37203229 | MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells |
| Q37175103 | Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes |
| Q33910902 | Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome |
| Q91826299 | Metabolic rewiring and redox alterations in malignant pleural mesothelioma |
| Q24299575 | Methylation of ribosomal protein S10 by protein-arginine methyltransferase 5 regulates ribosome biogenesis |
| Q48078774 | Mutations in the Type II protein arginine methyltransferase AtPRMT5 result in pleiotropic developmental defects in Arabidopsis. |
| Q36275660 | Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells |
| Q28544991 | NOX1 supports the metabolic remodeling of HepG2 cells |
| Q33971459 | Nuclear transport signals control cellular localization and function of androgen receptor cofactor p44/WDR77. |
| Q47731988 | PRMT1 is required for RAP55 to localize to processing bodies |
| Q92298803 | PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes |
| Q50287053 | PRMT5 binds WDR77 |
| Q89640752 | PRMT5 in gene regulation and hematologic malignancies |
| Q35009896 | PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.). |
| Q90704036 | PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia |
| Q33635946 | PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1. |
| Q43207028 | PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD). |
| Q43010726 | PRMT5: A novel regulator of Hepatitis B virus replication and an arginine methylase of HBV core |
| Q29871510 | PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145 |
| Q36415119 | Pinellia pedatisecta agglutinin interacts with the methylosome and induces cancer cell death |
| Q36804667 | Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. |
| Q41193415 | Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency |
| Q37021516 | Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase |
| Q38935888 | Protein arginine methylation/demethylation and cancer |
| Q24298151 | Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells |
| Q37398814 | Protein arginine methyltransferase 5 is essential for growth of lung cancer cells |
| Q28567709 | Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF |
| Q37145814 | Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation |
| Q30423422 | Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs |
| Q38012526 | Protein arginine methyltransferases (PRMTs) as therapeutic targets |
| Q38067063 | Protein arginine methyltransferases and cancer |
| Q92258681 | Protein arginine methyltransferases: insights into the enzyme structure and mechanism at the atomic level |
| Q37726342 | Protein arginine methyltransferases: nuclear receptor coregulators and beyond |
| Q37287579 | Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members |
| Q24322855 | Purification and identification of a novel complex which is involved in androgen receptor-dependent transcription |
| Q88749962 | Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy |
| Q38740198 | Recurring mutations in myeloproliferative neoplasms alter epigenetic regulation of gene expression |
| Q92796910 | Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma |
| Q37185632 | Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery |
| Q41864190 | RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. |
| Q42575278 | Role of pICLn in methylation of Sm proteins by PRMT5. |
| Q41694012 | SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation |
| Q28115292 | SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination |
| Q37272307 | SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes |
| Q38642785 | Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity |
| Q38104238 | Signaling through cyclin D-dependent kinases |
| Q34230914 | Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs |
| Q37994369 | Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy |
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| Q28585090 | The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression |
| Q28085672 | The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond |
| Q46442341 | The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer. |
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| Q28204829 | The SMN complex, an assemblyosome of ribonucleoproteins |
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