Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

scientific journal article

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCISIGNAL.2001936
P3181OpenCitations bibliographic resource ID4207490
P932PMC publication ID6312726
P698PubMed publication ID21917714
P5875ResearchGate publication ID51630050

P50authorJoan J Bech-SerraQ42774321
Carlos de TorreQ57365915
Rosaura Esteve-PuigQ60541957
Juan Angel RecioQ61820611
Matias AvilaQ73089673
Marta López-FauquedQ84655265
P2093author name stringGlenn Merlino
Elena R García-Trevijano
Francesc Canals
Pedro Andreu-Pérez
Stephan Tenbaum
P2860cites workKinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAFQ24298749
Regulation of p53 activity through lysine methylationQ24311514
A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptorQ24319127
Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanomaQ24685552
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analoguesQ27644429
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growthQ27659493
Activation mechanism of the MAP kinase ERK2 by dual phosphorylationQ27743261
The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activityQ27931859
Arginine methylation regulates the p53 responseQ28116284
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase familyQ28142367
A novel WD repeat protein component of the methylosome binds Sm proteinsQ28213642
Met, metastasis, motility and moreQ28235183
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAFQ28251989
Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylationQ28304227
Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAFQ28474973
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fateQ28576088
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functionsQ29547189
The diverse functions of histone lysine methylationQ29614523
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAFQ29616828
Protein arginine methylation in mammals: who, what, and whyQ29617309
Arginine methylation an emerging regulator of protein functionQ29617311
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancerQ29618155
The RAF proteins take centre stageQ29620153
Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcriptionQ33938819
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cellsQ33940377
State of the arg: protein methylation at arginine comes of age.Q34084396
Methylthioadenosine.Q35864131
The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homologQ35931595
In vivo and in vitro arginine methylation of RNA-binding proteinsQ36551118
Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potentialQ36605563
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathwayQ36637883
Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulationQ37155394
Increased apoptosis after autoimmune regulator expression in epithelial cells revealed by a combined quantitative proteomics approach.Q39729662
Quantitative analysis of 5'-deoxy-5'-methylthioadenosine in melanoma cells by liquid chromatography-stable isotope ratio tandem mass spectrometryQ39919555
Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.Q40149301
In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signalingQ40224091
Post-translational modification of H-Ras is required for activation of, but not for association with, B-RafQ41224854
Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell linesQ41253565
PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cellsQ41724415
Signal transduction through MAP kinase cascadesQ41750250
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradationQ41825679
The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.Q41895997
Arginine methylation regulates IL-2 gene expression: a role for protein arginine methyltransferase 5 (PRMT5).Q41927743
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factorQ41978360
NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levelsQ43976612
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionineQ44378796
SB203580 promotes EGF-stimulated early morphological differentiation in PC12 cell through activating ERK pathwayQ46107993
PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activationQ47995280
Polycomb group protein ezh2 controls actin polymerization and cell signaling.Q53676862
PRMT5 (Janus Kinase-binding Protein 1) Catalyzes the Formation of Symmetric Dimethylarginine Residues in ProteinsQ56227906
Control of MAPK signalling: from complexity to what really mattersQ57393852
Principles behind the multifarious control of signal transductionQ57393856
Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulationQ57903814
P433issue190
P304page(s)ra58
P577publication date2011-09-01
P1433published inScience SignalingQ7433604
P1476titleProtein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF
P478volume4

Reverse relations

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