PRMT5 regulates T cell interferon response and is a target for acute graft-versus-host disease

scientific article published on 19 March 2020

PRMT5 regulates T cell interferon response and is a target for acute graft-versus-host disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI.INSIGHT.131099
P932PMC publication ID7205431
P698PubMed publication ID32191634

P50authorNina C ZitzerQ63634543
P2093author name stringMin Wang
Hong Lin
Robert A Baiocchi
Kris Vaddi
Ramiro Garzon
Parvathi Ranganathan
Jane E Jackman
Charuta Kale
Hannah K Choe
Yandi Gao
Maciej Pietrzak
Gregory K Behbehani
Yang W Zhang
Maria G Abad
Katiri Snyder
Anora Ignaci
Lotus Neidemire-Colley
Natalie E Sell
Raymond D Devine
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Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host diseaseQ36843812
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IL-17 contributes to CD4-mediated graft-versus-host diseaseQ37071147
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PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB.Q37103890
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PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune EncephalomyelitisQ37625481
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Novel approaches for preventing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantationQ38816505
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MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function.Q52714530
Adoptively transferred donor IL-17-producing CD4+ T cells augment, but IL-17 alleviates, acute graft-versus-host disease.Q52880882
Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.Q52932701
Addition of 10-Day Decitabine to Fludarabine/Total Body Irradiation Conditioning is Feasible and Induces Tumor-Associated Antigen-Specific T Cell ResponsesQ57019922
Donor interleukin-22 and host type I interferon signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10Q57194209
The interferon-dependent orchestration of innate and adaptive immunity after transplantationQ57252623
Type I-IFNs control GVHD and GVL responses after transplantationQ57252624
IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tractQ57252630
In vitro-established alloantigen-specific CD8+ CTLs mediate graft-versus-tumor activity in the absence of graft-versus-host diseaseQ57384554
Arginine methylation controls the strength of γc-family cytokine signaling in T cell maintenanceQ57464781
In vitro Th17-polarized human CD4 T cells exacerbate xenogeneic graft-versus-host diseaseQ57468066
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Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cellsQ74098005
Graft-versus-leukemia effect and graft-versus-host disease can be differentiated by cytotoxic mechanisms in a murine model of allogeneic bone marrow transplantationQ77293917
IL-17-producing T cells contribute to acute graft-versus-host disease in patients undergoing unmanipulated blood and marrow transplantationQ83300076
Graft-versus-host diseaseQ83468020
Background to hematopoietic cell transplantation, including post transplant immune recoveryQ84794952
P577publication date2020-03-19
P1433published inJCI insightQ27727187
P1476titlePRMT5 regulates T cell interferon response and is a target for acute graft-versus-host disease

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