scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1024510095 |
P356 | DOI | 10.1038/179663A0 |
P3181 | OpenCitations bibliographic resource ID | 2213308 |
P698 | PubMed publication ID | 13418758 |
P2093 | author name string | C HEIDELBERGER | |
J SCHEINER | |||
P DANNEBERG | |||
R J SCHNITZER | |||
N K CHAUDHURI | |||
R DUSCHINSKY | |||
D MOOREN | |||
E PLEVEN | |||
L GRIESBACH | |||
P2860 | cites work | Chromatographic studies of nucleic acids; a technique for the identification and estimation of purine and pyrimidine bases, nucleosides and related substances | Q42626913 |
Studies of nucleic acid synthesis in ascites tumor cells | Q74007787 | ||
The fate of 6-mercaptopurine in mice | Q78573325 | ||
The in vivo formation of citrate induced by fluoroacetate and its significance | Q80655039 | ||
The Separation of Purine and Pyrimidine Bases and of Nucleotides by Ion Exchange | Q80929979 | ||
P433 | issue | 4561 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 663-6 | |
P577 | publication date | 1957-03-30 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Fluorinated pyrimidines, a new class of tumour-inhibitory compounds | |
P478 | volume | 179 |
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Q38603038 | P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting. |
Q72680305 | Palliative and adjunctive measures in rectal cancer |
Q37114275 | Participation of DNA repair in the response to 5-fluorouracil |
Q48322740 | Paul Ehrlich's magic bullet concept: 100 years of progress |
Q55107856 | Perioperative chemotherapy with pemetrexed and cisplatin for pulmonary large-cell neuroendocrine carcinoma: a case report and literature review. |
Q44987455 | Peripheal blood toxicity of topical 5-fluorouracil on the Syrian hamster cheek pouch |
Q38166233 | Personalizing colon cancer therapeutics: targeting old and new mechanisms of action. |
Q36326214 | Pharmacogenetics of colorectal cancer |
Q34008793 | Pharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 years |
Q42691338 | Pharmacogenomics DNA Biomarkers in Colorectal Cancer: Current Update |
Q35873676 | Pharmacogenomics and stomach cancer. |
Q36441493 | Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy |
Q37728873 | Pharmacokinetic evaluation of novel oral fluorouracil antitumor drug S-1 in Chinese cancer patients |
Q33581242 | Pharmacokinetic properties and antitumor efficacy of the 5-fluorouracil loaded PEG-hydrogel |
Q55040229 | Pharmacokinetics of continuous transarterial infusion of 5-fluorouracil in patients with advanced hepatocellular carcinoma. |
Q26769850 | Pharmacologic resistance in colorectal cancer: a review |
Q37500096 | Pharmacology and pharmacogenetics of chemotherapeutic agents |
Q42793414 | Pharmacology of perioperative 5‐Fluorouracil |
Q43280939 | Pharmacology, pharmacogenetics, and pharmacoepidemiology: three ps of individualized therapy |
Q67993427 | Phase II study of gemcitabine in advanced colorectal adenocarcinoma |
Q47268080 | Phosphoribosyl pyrophosphate, pool size and tissue levels as a determinant of 5-fluorouracil response in murine colonic adenocarcinomas |
Q30426511 | Plant-derived anticancer agents |
Q36420719 | Positron emission tomography measurement of tumor metabolism and growth: its expanding role in oncology |
Q59069547 | Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours |
Q37406869 | Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy |
Q37311933 | Preclinical screening methods in cancer |
Q44458788 | Prediction of sensitivity to fluoropyrimidines by metabolic and target enzyme activities in gastric cancer |
Q33320579 | Predictive value of Ki67 and p53 in locally advanced rectal cancer: correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy |
Q68445322 | Preoperative irradiation and 5-fluorouracil suppository for carcinoma of the rectum |
Q38232067 | Priming cancer cells for drug resistance: role of the fibroblast niche |
Q34325743 | Programmed chemotherapy for patients with metastatic unresectable gastric cancer. |
Q35039113 | Proteomic analysis of differentially expressed proteins in 5-fluorouracil-treated human breast cancer MCF-7 cells |
Q34347434 | Protonation preferentially stabilizes minor tautomers of the halouracils: IRMPD action spectroscopy and theoretical studies. |
Q26865050 | Pseudouridines in spliceosomal snRNAs |
Q34019673 | Pyrimidine metabolism in man. V. The measurement in vivo of the biochemical effect of antineoplastic agents in animal and human subjects |
Q76898304 | RADIOAUTOGRAPHIC STUDY OF THE EFFECTS OF 5-FLUORODEOXYURIDINE, ACTINOMYCIN AND PUROMYCIN IN ACETABULARIA MEDITERANEA |
Q46446260 | Radiation dose estimates for [18F]5-fluorouracil derived from PET-based and tissue-based methods in rats |
Q59081922 | Radiosensitization Of E. Coli by Purine and Pyrimidine Analogues Incorporated in Deoxyribonucleic Acid |
Q35009893 | Raltitrexed: optimism and reality |
Q38268619 | Recent studies of 5-fluorouracil resistance in pancreatic cancer |
Q35556789 | Reexamining a proposal: thymidylate synthase 5'-untranslated region as a regulator of translation efficiency. |
Q38211868 | Relationship between head and neck cancer therapy and some genetic endpoints |
Q69934719 | Reminiscence and experience in experimental chemotherapy of cancer |
Q40187481 | Repurposing of nucleoside- and nucleobase-derivative drugs as antibiotics and biofilm inhibitors. |
Q26781245 | Research into cancer metabolomics: Towards a clinical metamorphosis |
Q35567272 | Resistance to antifolates |
Q41398588 | Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage |
Q64997072 | Ribose-transfer Activity from Uridine to 5-Fluorouracil in Ehrlich Ascites Tumor Cells |
Q47849564 | Routes to drug design via bioisosterism of carboxyl and sulfonamide groups. |
Q37974935 | S-1 as a core anticancer fluoropyrimidine agent |
Q27700205 | Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo |
Q39312759 | Semisynthetic ursolic acid fluorolactone derivatives inhibit growth with induction of p21(waf1) and induce apoptosis with upregulation of NOXA and downregulation of c-FLIP in cancer cells |
Q35969001 | Shizukaol D, a Dimeric Sesquiterpene Isolated from Chloranthus serratus, Represses the Growth of Human Liver Cancer Cells by Modulating Wnt Signalling Pathway |
Q40138085 | Solid Tumor Models for the Assessment of Different Treatment Modalities: VI: Perturbations in the Kinetics of Tumor and Host Organ Cellular Regulation Demonstrated by Single and Combined Experimental Therapy |
Q39961474 | Specific targeting of prostate cancer cells in vitro by the suicide gene/prodrug system, uracil phosphoribosyltransferase/5-fluorouracil, under the control of prostate-specific membrane antigen promoter/enhancer |
Q27006500 | Splice isoforms as therapeutic targets for colorectal cancer |
Q38204673 | Standing the test of time: targeting thymidylate biosynthesis in cancer therapy |
Q27675656 | Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs |
Q42254777 | Structure-activity relationship of 1-propargyl-5-halopyrimidin-2-ones. Metaphase arresting properties and competitive inhibition of colchicine binding to tubulin |
Q42697416 | Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues |
Q46206827 | Studies on the mechanism of fluoropyrimidine cytotoxicity in l1210 cells: correlation with inhibition of thymidylate synthetase but not with incorporation into RNA. |
Q44941786 | Study on the role of 5-fluorouracil in the polymerization of butylcyanoacrylate during the formation of nanoparticles. |
Q33416158 | Survival benefit from S-1 as compared to Fluorouracil in Asian patients with advanced gastrointestinal cancer: a meta-analysis. |
Q37901554 | Symptomatic 5-fluorouracil-induced sinus bradycardia |
Q40264235 | Synergy between expression of fusogenic membrane proteins, chemotherapy and facultative virotherapy in colorectal cancer. |
Q40038143 | Synthesis and bioevaluation of 5-fluorouracil derivatives. |
Q52933943 | Synthesis and biological applications of fluoro-modified nucleic acids. |
Q40050432 | Synthesis and biological evaluation of new 4beta-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives |
Q39709630 | Synthesis and biological evaluation of new 5-fluorouracil-substituted ampelopsin derivatives. |
Q39329841 | Synthesis of PEGylated fullerene-5-fluorouracil conjugates to enhance the antitumor effect of 5-fluorouracil |
Q35111704 | Synthesis of novel spin-labeled derivatives of 5-FU as potential antineoplastic agents |
Q42227659 | Synthesis of potential pyrimidine derivatives via Suzuki cross-coupling reaction as HIV and kinesin Eg5 inhibitors. |
Q40258494 | Synthesis of virulence factors by Pasteurella pestis |
Q37909031 | Synthesis, reactivity and biological activity of 5-alkoxymethyluracil analogues. |
Q38796140 | Systemic Antifungal Agents: Current Status and Projected Future Developments. |
Q44249171 | Systemic chemotherapy for metastatic colorectal cancer: reasons to combine |
Q37109507 | Systemic therapy for metastatic colorectal cancer: current questions |
Q36529843 | Systemic therapy strategies for head-neck carcinomas: Current status |
Q38597310 | TAS-102, a novel antitumor agent: a review of the mechanism of action |
Q38652269 | TAS-102: a novel antimetabolite for the 21st century |
Q77156773 | THE EFFECT OF 5-IODO-2'-DESOXYURIDINE ON THE PROPAGATION OF SV 40 VIRUS IN TISSUE CULTURE |
Q33994714 | THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES |
Q35973877 | Tailored chemotherapy for colorectal cancer: a new approach to therapy |
Q92747984 | Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer |
Q47646742 | Targeting Metabolism for Cancer Therapy. |
Q35599748 | Tegafur/gimeracil/oteracil (S-1) approved for the treatment of advanced gastric cancer in adults when given in combination with cisplatin: a review comparing it with other fluoropyrimidine-based therapies |
Q33815796 | The Mutator Phenotype in Cancer: Molecular Mechanisms and Targeting Strategies |
Q39233316 | The Role of Fluoropirimidines in Gastrointestinal Tumours: from the Bench to the Bed. |
Q37795648 | The Unique Potential for Noninvasive Imaging in Modernizing Drug Development and in Transforming Therapeutics: PET/MRI/MRS |
Q78907567 | The biosynthesis of poliovirus in cell cultures |
Q34054268 | The clinical impact of screening and other experimental tumor studies |
Q34980526 | The dual role of thymidine phosphorylase in cancer development and chemotherapy |
Q34761260 | The effect of dihydropyrimidine dehydrogenase deficiency on outcomes with fluorouracil |
Q39638939 | The effect of leucovorin on the therapeutic index of fluorouracil in cancer patients |
Q42198572 | The effect of structural modifications of 5-fluorouracil derivatives on their transport and biodegradation by isolated rat jejunum |
Q39927801 | The emergence of drug resistance in tumours: a characteristic which may be exploited therapeutically |
Q52507634 | The essential role of folic acid and the effect of antimetabolites on growth and metamorphosis of housefly larvae Musca domestica L |
Q51776805 | The high-affinity maltose switch MBP317-347 has low affinity for glucose: implications for targeting tumors with metabolically directed enzyme prodrug therapy. |
Q52334121 | The mechanistic basis of pH-dependent 5-flucytosine resistance in Aspergillus fumigatus. |
Q40003629 | The metabolism and pharmacology of 5-fluorouracil |
Q72893958 | The metabolism of 5-fluorocytosine-214C and of cytosine-14C in the rat and the disposition of 5-fluorocytosine-214C in man |
Q34211250 | The oral fluorinated pyrimidines |
Q78983322 | The polymerization of 8-Azaguanosine 5′-diphosphate by polynucleotide phosphorylase |
Q33352896 | The potentiation of radiation effects with 5-fluoro-uracil |
Q53692873 | The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature. |
Q35602147 | The role of funding and policies on innovation in cancer drug development |
Q72720011 | The synthesis, characterization and biological properties of a new substance, 5-fluoropyrimidin-2-one |
Q36038314 | The value of fluorinated pyrimidines in advanced malignancy |
Q44929190 | Therapeutic evaluation of intralesional 5% 5-fluorouracil in condyloma acuminata |
Q33884698 | Therapeutic strategies with oral fluoropyrimidine anticancer agent, S-1 against oral cancer |
Q24633384 | Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan |
Q71832497 | Thermodynamic and Kinetic Aspects of the Reaction of γ-Fluoroglutamate with d-Glutamate Cyclase |
Q34216779 | Thymidine analogues for tracking DNA synthesis. |
Q39940923 | Thymidylate Synthetase |
Q35183525 | Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment |
Q81481891 | Thymidylate synthase gene polymorphism as a prognostic factor for colon cancer |
Q43932425 | Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy |
Q40960400 | Thymidylate synthase in advanced gastrointestinal and breast cancers |
Q37379373 | Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer |
Q35549719 | Thymidylate synthetase - a target enzyme in cancer chemotherapy |
Q40442939 | Topical and systemic antifungals in dermatology practice. |
Q40307900 | Topical chemotherapy with 5-fluorouracil. A review |
Q71299502 | Topical cytotoxic therapy of solar keratoses with 5-fluorouracil |
Q70576748 | Topical therapy with 5‐fluorouracil |
Q37207935 | Topoisomerase I and IIalpha protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy |
Q80554169 | Topoisomerase I protein expression in primary colorectal cancer and recurrences after 5-FU-based adjuvant chemotherapy |
Q34438530 | Tramadol--a true natural product? |
Q33233929 | Treatment of Genital Condylomata with Topical 5-Fluorouracil |
Q33468659 | Treatment of cancer with weekly intravenous 5-fluorouracil.Study by the Western Cooperative Cancer Chemotherapy Group (WCCCG) |
Q37255172 | Treatment of invasive candidiasis in immunocompromised pediatric patients |
Q70580395 | Treatment of metastatic colorectal carcinoma with 5-fluorouracil by mouth |
Q26774713 | Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancer |
Q71843761 | Tumor retention of 5-fluorouracil following irradiation observed using 19F nuclear magnetic resonance spectroscopy |
Q35553869 | UFT and Oral Leucovorin as Radiation Sensitizers in Rectal and Other Gastrointestinal Malignancies |
Q47129907 | Uncovering Large-Scale Conformational Change in Molecular Dynamics without Prior Knowledge |
Q39789627 | Update in cancer chemotherapy: gastrointestinal cancer--colorectal cancer, Part 1. |
Q79064008 | Use of 5-Fluorouracil in Disseminated Solid Neoplasms |
Q35212953 | Use of capecitabine in management of early colon cancer |
Q38997864 | Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects. |
Q42916637 | Variants in the Dihydropyrimidine Dehydrogenase, Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genes Predict Early Toxicity of 5-Fluorouracil in Colorectal Cancer Patients |
Q39406815 | What's new in treatment of pancreatic cancer: a patent review (2010-2017). |
Q46906887 | Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells |
Q37425429 | XIII International Charles Heidelberger Symposium and 50 Years of Fluoropyrimidines in Cancer Therapy Held on september 6 to 8, 2007 at New York University Cancer Institute, Smilow Conference Center |
Q78560478 | [Chemotherapy & bacterial resistance] |
Q33532192 | [Human papillomavirus-associated warts in organ transplant recipients. Incidence, risk factors, management]. |
Q33727842 | dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial |
Q41767730 | dUTPase inhibition augments replication defects of 5-Fluorouracil. |
Q33754032 | microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression |
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