A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.

scientific article published on October 2003

A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/SJ.ONC.1206941
P698PubMed publication ID14576845
P5875ResearchGate publication ID232773887

P50authorDavid A. BoothmanQ57617884
P2093author name stringMartina L Veigl
Mark Meyers
Mark W Wagner
W David Sedwick
Arlene Hwang
Andrew J Bruening
P2860cites workMED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1Q22009114
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Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancerQ24614511
Effects of 5-fluorouracil/guanine wobble base pairs in Z-DNA: molecular and crystal structure of d(CGCGFG)Q27728500
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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosisQ28138604
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Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylaseQ28142841
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Lessons learned from structural results on uracil-DNA glycosylaseQ28143925
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Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1Q28212223
Fluorinated pyrimidines, a new class of tumour-inhibitory compoundsQ28214124
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Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitorsQ28610372
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5-Fluorodeoxyuridine as an alternative to the synthesis of mixed hybridization probes for the detection of specific gene sequencesQ33559038
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From p63 to p53 across p73.Q34164614
DNA mismatch repair and cancerQ34164892
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?Q34180691
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Mismatch correction at O 6 -methylguanine residues in E. coli DNAQ59049241
Structural and dynamic properties of a bromouracil-adenine base pair in DNA studied by proton NMRQ68113468
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Molecular mechanisms of DNA mismatch repairQ34293069
Functional interactions and signaling properties of mammalian DNA mismatch repair proteinsQ34425450
5-Fluoro-2′-Deoxyuridylate: Covalent Complex with Thymidylate SynthetaseQ34715827
Antifolate-induced misincorporation of deoxyuridine monophosphate into DNA: inhibition of high molecular weight DNA synthesis in human lymphoblastoid cellsQ35419324
Proliferation of mutators in A cell populationQ35618973
Studies on gene control regions XII. The functional significance of a Lac operator constitutive mutationQ35759243
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.Q36213486
Perturbations of enzymic uracil excision due to purine damage in DNA.Q36307482
Metabolism and mechanism of action of 5-fluorodeoxycytidineQ36317610
Methotrexate-induced misincorporation of uracil into DNA.Q36363196
hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damageQ36538872
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cellsQ36617515
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Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidineQ37357197
Anticarcinogenic potential of DNA-repair modulatorsQ39488551
Interactions between deoxyribonucleotide and DNA synthesisQ39532113
Ribonucleotide reductase and deoxyribonucleotide pools.Q39819783
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DNA damage tolerance, mismatch repair and genome instabilityQ40582064
Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cellsQ40671782
Comparison of 5-fluoro-2'-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancerQ40853983
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Inhibitors of thymine nucleotide biosynthesis: antimetabolites that provoke genetic change via primary non-DNA targetsQ41090682
Strand-specific mismatch repair in mammalian cellsQ41602506
Catalytic mechanism and inhibition of tRNA (uracil-5-)methyltransferase: evidence for covalent catalysisQ42212909
Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cellsQ43755586
Mechanisms of tolerance to DNA damaging therapeutic drugsQ43829355
ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylationQ44085060
Substrate recognition by a family of uracil-DNA glycosylases: UNG, MUG, and TDG.Q44107139
Deoxyuridine triphosphatase: a potential site of interaction with pyrimidine nucleotide analoguesQ44339871
Interaction of deoxyuridine with fluorouracil and dipyridamole in a human colon cancer cell lineQ44648979
5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylaseQ46224336
Mismatch repair, molecular switches, and signal transductionQ47787090
High mutation frequencies among Escherichia coli and Salmonella pathogensQ48057867
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.Q50320380
Mechanisms of Action and Modulation of Fluorouracil.Q52170109
Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia.Q53399548
The specific mutagenic effect of base analogues on Phage T4Q54094851
Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation.Q54300596
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectDNA mismatch repairQ2984243
P304page(s)7376-7388
P577publication date2003-10-01
P1433published inOncogeneQ1568657
P1476titleA role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage
P478volume22