| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1999PNAS...9612384D |
| P356 | DOI | 10.1073/PNAS.96.22.12384 |
| P932 | PMC publication ID | 22926 |
| P698 | PubMed publication ID | 10535931 |
| P5875 | ResearchGate publication ID | 12764584 |
| P2093 | author name string | Y Taya | |
| P Modrich | |||
| D R Duckett | |||
| S M Bronstein | |||
| P2860 | cites work | A role for ATR in the DNA damage-induced phosphorylation of p53 | Q22008733 |
| The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage | Q22010200 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| Mutation of a mutL homolog in hereditary colon cancer | Q28114939 | ||
| DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 | Q28254119 | ||
| Transcription-coupled repair deficiency and mutations in human mismatch repair genes | Q28276963 | ||
| Biochemistry and genetics of eukaryotic mismatch repair | Q28282377 | ||
| The complexity of p53 modulation: emerging patterns from divergent signals | Q28284854 | ||
| Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells | Q28292781 | ||
| Mutations of GTBP in genetically unstable cells | Q28292802 | ||
| Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer | Q28294774 | ||
| Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
| Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha | Q28610863 | ||
| Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
| Mismatch repair in replication fidelity, genetic recombination, and cancer biology | Q29616483 | ||
| p53: puzzle and paradigm | Q29618407 | ||
| ATM associates with and phosphorylates p53: mapping the region of interaction | Q30175960 | ||
| Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. | Q30450287 | ||
| Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines | Q33720790 | ||
| p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts | Q33986335 | ||
| Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs | Q34554581 | ||
| Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins. | Q34625095 | ||
| DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
| Self-destruction and tolerance in resistance of mammalian cells to alkylation damage | Q36277253 | ||
| An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. | Q36412005 | ||
| Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems | Q36565271 | ||
| Identification of p53 genetic suppressor elements which confer resistance to cisplatin | Q36843916 | ||
| Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389 | Q37413761 | ||
| Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct | Q37522716 | ||
| Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage | Q38320078 | ||
| Specific binding of human MSH2.MSH6 mismatch-repair protein heterodimers to DNA incorporating thymine- or uracil-containing UV light photoproducts opposite mismatched bases. | Q38324036 | ||
| MutS and MutL activate DNA helicase II in a mismatch-dependent manner | Q38337755 | ||
| Mismatch repair and the fidelity of genetic recombination | Q38730984 | ||
| Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation | Q39715750 | ||
| The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro | Q40023550 | ||
| DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage | Q40942428 | ||
| DNA-dependent protein kinase acts upstream of p53 in response to DNA damage | Q41013003 | ||
| Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line | Q41174585 | ||
| Loss of DNA mismatch repair in acquired resistance to cisplatin | Q41189901 | ||
| Spectra of Spontaneous and X-Ray-Induced Mutations at the hprt Locus in Related Human Lymphoblast Cell Lines That Express Wild-Type or Mutant p53 | Q41302855 | ||
| Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint | Q41303489 | ||
| p53 and ATM: cell cycle, cell death, and cancer. | Q41438652 | ||
| Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation | Q41448577 | ||
| Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine. | Q41472481 | ||
| Mispair specificity of methyl-directed DNA mismatch correction in vitro | Q44909730 | ||
| Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin. | Q46145400 | ||
| Involvement of the mismatch repair system in temozolomide-induced apoptosis | Q47752780 | ||
| DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma | Q48331144 | ||
| Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting. | Q52525643 | ||
| Reversal of methylation tolerance by transfer of human chromosome 2. | Q53437948 | ||
| A mutator phenotype characterizes one of two complementation groups in human cells tolerant to methylation damage. | Q54170205 | ||
| Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft. | Q55478338 | ||
| Heteroduplex repair in extracts of human HeLa cells | Q68198738 | ||
| Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibition | Q69811351 | ||
| The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin | Q71533749 | ||
| p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells | Q77138780 | ||
| Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells | Q78124992 | ||
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 12384-12388 | |
| P577 | publication date | 1999-10-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage | |
| P478 | volume | 96 |
| Q39768066 | 3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model. |
| Q35567250 | A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage. |
| Q40811043 | A role for mismatch repair in control of DNA ploidy following DNA damage |
| Q44085060 | ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation |
| Q24564010 | ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage |
| Q24337520 | ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts |
| Q35605612 | Aberrant crypt foci as microscopic precursors of colorectal cancer |
| Q38288867 | Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line |
| Q34241602 | Alkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O6-alkylguanine adducts in Escherichia coli. |
| Q35876010 | Apoptosis and genomic instability |
| Q40720210 | Association of p53 and MSH2 with recombinative repair complexes during S phase |
| Q24606873 | BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures |
| Q37647252 | Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions |
| Q36693771 | Chemotherapeutic implications in microsatellite unstable colorectal cancer |
| Q40811649 | Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. |
| Q33559854 | Construction and characterization of mismatch-containing circular DNA molecules competent for assessment of nick-directed human mismatch repair in vitro |
| Q39345494 | Cucurbit[7]uril encapsulated cisplatin overcomes cisplatin resistance via a pharmacokinetic effect. |
| Q40599733 | Cyclin D1 expression and cell cycle response in DNA mismatch repair-deficient cells upon methylation and UV-C damage |
| Q36604609 | DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen |
| Q38595733 | DNA excision repair at telomeres |
| Q34164892 | DNA mismatch repair and cancer |
| Q36540658 | DNA mismatch repair and the DNA damage response |
| Q34568596 | DNA mismatch repair defects: role in colorectal carcinogenesis |
| Q28291067 | DNA mismatch repair in eukaryotes and bacteria |
| Q36453321 | DNA mismatch repair system. Classical and fresh roles |
| Q41175947 | DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. |
| Q34141513 | DNA mismatch repair: MutS structures bound to mismatches. |
| Q28295863 | DNA replication fidelity and cancer |
| Q40874476 | Decreased UV sensitivity, mismatch repair activity and abnormal cell cycle checkpoints in skin cancer cell lines derived from UVB-irradiated XPA-deficient mice |
| Q37328459 | Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice. |
| Q35946397 | Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres |
| Q37251186 | Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells |
| Q64104986 | Dose-dependent spatiotemporal responses of mammalian cells to an alkylating agent |
| Q30484429 | Evolutionary origins of human apoptosis and genome-stability gene networks |
| Q34918066 | Exposure to the polyester PET precursor--terephthalic acid induces and perpetuates DNA damage-harboring non-malignant human breast cells |
| Q35559704 | Folate deficiency, mismatch repair-dependent apoptosis, and human disease |
| Q34425450 | Functional interactions and signaling properties of mammalian DNA mismatch repair proteins |
| Q33836026 | Genomic and epigenetic instability in colorectal cancer pathogenesis |
| Q73810802 | Great leaps forward: translesion synthesis gets unstalled |
| Q57247926 | Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background |
| Q33950079 | High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6. |
| Q33554104 | Human MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells |
| Q39913958 | Human MutL-complexes monitor homologous recombination independently of mismatch repair |
| Q43514135 | Human mismatch repair and G*T mismatch binding by hMutSalpha in vitro is inhibited by adriamycin, actinomycin D, and nogalamycin |
| Q37371661 | In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system |
| Q47965756 | Increased hMSH2 protein expression in glioblastoma multiforme |
| Q24648193 | Increased sensitivity of p53-deficient cells to anticancer agents due to loss of Pms2 |
| Q34354462 | Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells |
| Q39991083 | Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine |
| Q33812133 | Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1 |
| Q45144500 | Interaction of checkpoint proteins Hus1/Rad1/Rad9 with DNA base excision repair enzyme MutY homolog in fission yeast, Schizosaccharomyces pombe |
| Q24553992 | Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin |
| Q45458727 | Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions |
| Q33648599 | Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway |
| Q28209230 | Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX |
| Q58074454 | Involvement of DNA mismatch repair in folate deficiency-induced apoptosis☆ |
| Q38350366 | MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine |
| Q24301197 | MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation |
| Q43829355 | Mechanisms of tolerance to DNA damaging therapeutic drugs |
| Q73311211 | Mediating mismatch repair |
| Q35019055 | Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1 |
| Q24556572 | Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2 |
| Q33885063 | Mismatch repair defects in cancer |
| Q34194518 | Mismatch repair in correction of replication errors and processing of DNA damage |
| Q74080033 | Mismatch repair in human nuclear extracts. Quantitative analyses of excision of nicked circular mismatched DNA substrates, constructed by a new technique employing synthetic oligonucleotides |
| Q41954072 | Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts |
| Q35208840 | Molecular markers in clinical radiation oncology |
| Q37413511 | Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas |
| Q37037194 | O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo |
| Q57664836 | Polymorphisms inXPD,XPCand the risk of death in patients with urinary bladder neoplasms |
| Q47116638 | Pooling-analysis on hMLH1 polymorphisms and cancer risk: evidence based on 31,484 cancer cases and 45,494 cancer-free controls |
| Q37359608 | Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response |
| Q28537881 | Reactive oxygen species mediate Epstein-Barr virus reactivation by N-methyl-N'-nitro-N-nitrosoguanidine |
| Q35026401 | RecQ family helicases: roles as tumor suppressor proteins |
| Q56565998 | Reduced expression of hMSH2 protein is correlated to poor survival for soft tissue sarcoma patients |
| Q40785979 | Reduction of spontaneous mutagenesis in mismatch repair-deficient and proficient cells by dietary antioxidants |
| Q35910747 | Role of DNA mismatch repair in apoptotic responses to therapeutic agents |
| Q39982450 | Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses. |
| Q34057743 | Roles for mismatch repair factors in regulating genetic recombination |
| Q43915766 | SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression |
| Q34103450 | Simple and rapid preparation of gapped plasmid DNA for incorporation of oligomers containing specific DNA lesions |
| Q28143945 | Structure and function of mismatch repair proteins |
| Q27935147 | The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo. |
| Q44107666 | The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice |
| Q52575540 | The cell cycle and DNA mismatch repair. |
| Q90701937 | The deaminase APOBEC3B triggers the death of cells lacking uracil DNA glycosylase |
| Q34989790 | The genetic pathogenesis of colorectal cancer |
| Q40570055 | The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase |
| Q36925829 | The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine |
| Q35076298 | Therapeutic modulation of epigenetic drivers of drug resistance in ovarian cancer |
| Q36296721 | Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide |
| Q80518102 | Transcription - guarding the genome by sensing DNA damage |
| Q34276816 | hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro |
| Q42826973 | p53 Phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor-1 (PAI-1) gene by the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine |
| Q40855467 | p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV. |
| Q38302465 | p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents |
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