scholarly article | Q13442814 |
P2093 | author name string | Levine AJ | |
Bailey P | |||
Lu H | |||
Fisher RP | |||
P2860 | cites work | Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene | Q24298218 |
Cdk-activating kinase complex is a component of human transcription factor TFIIH | Q24306759 | ||
In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein | Q24310168 | ||
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death | Q24312211 | ||
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway | Q24336089 | ||
p53 modulation of TFIIH–associated nucleotide excision repair activity | Q24336880 | ||
Human TAFII31 protein is a transcriptional coactivator of the p53 protein | Q24562978 | ||
The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor | Q24595611 | ||
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53 | Q24609153 | ||
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
p53, the cellular gatekeeper for growth and division | Q27860990 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Association of Cdk-activating kinase subunits with transcription factor TFIIH | Q28236002 | ||
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein | Q28238628 | ||
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase | Q28247022 | ||
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II | Q28251866 | ||
p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 | ||
Induction of the growth inhibitor IGF-binding protein 3 by p53 | Q28289896 | ||
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene | Q28306186 | ||
The p53-mdm-2 autoregulatory feedback loop | Q28609811 | ||
Mapping of the p53 and mdm-2 Interaction Domains | Q28609886 | ||
Allosteric activation of latent p53 tetramers | Q28623087 | ||
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia | Q29615437 | ||
Participation of p53 protein in the cellular response to DNA damage | Q29618319 | ||
Factors involved in specific transcription by mammalian RNA polymerase II. Identification and characterization of factor IIH | Q55043488 | ||
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II | Q59098636 | ||
p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes | Q70993632 | ||
p53 Protein exhibits 3'-to-5' exonuclease activity | Q71170481 | ||
Blockage of RNA polymerase as a possible trigger for u.v. light-induced apoptosis | Q71408610 | ||
Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases | Q71614374 | ||
U.v.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle | Q72185052 | ||
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots | Q72693767 | ||
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours | Q29618396 | ||
p53: puzzle and paradigm | Q29618407 | ||
Atm-deficient mice: a paradigm of ataxia telangiectasia | Q29619532 | ||
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor | Q29619833 | ||
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2 | Q33643799 | ||
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues | Q34057186 | ||
CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15. | Q34057245 | ||
Monoclonal antibodies specific for simian virus 40 tumor antigens | Q34249232 | ||
The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity | Q34252975 | ||
Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases | Q34298718 | ||
Cloning of the 62-kilodalton component of basic transcription factor BTF2. | Q34338584 | ||
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2 | Q34356650 | ||
Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells | Q35589990 | ||
Mammalian DNA nucleotide excision repair reconstituted with purified protein components. | Q36697936 | ||
The mdm-2 gene is induced in response to UV light in a p53-dependent manner | Q36717209 | ||
Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells | Q36781515 | ||
Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein | Q37332768 | ||
Role of phosphorylation in p34cdc2 activation: identification of an activating kinase | Q37370012 | ||
The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex | Q37617641 | ||
Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus | Q38294071 | ||
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches | Q38294077 | ||
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair | Q38313225 | ||
Regulation of the specific DNA binding function of p53 | Q38324290 | ||
mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein | Q40018842 | ||
Where transcription meets repair | Q40739628 | ||
The p53 tumor suppressor gene. | Q40761463 | ||
p40MO15 associates with a p36 subunit and requires both nuclear translocation and Thr176 phosphorylation to generate cdk-activating kinase activity in Xenopus oocytes | Q40793691 | ||
p53 in growth control and neoplasia | Q41009705 | ||
Oxidative stress is involved in the UV activation of p53. | Q41200949 | ||
p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. | Q41360603 | ||
Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression. | Q41548662 | ||
Presence of a potent transcription activating sequence in the p53 protein | Q41724404 | ||
The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor | Q42494377 | ||
Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate | Q42811171 | ||
Phosphorylation of the p53 tumour-suppressor protein at three N-terminal sites by a novel casein kinase I-like enzyme | Q42818286 | ||
Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo | Q42827016 | ||
DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. | Q45041158 | ||
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. | Q45985375 | ||
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. | Q45993768 | ||
Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase | Q46760600 | ||
Mutations in the p53 and SCID genes cooperate in tumorigenesis. | Q52200235 | ||
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors. | Q52200236 | ||
Dual roles of ATM in the cellular response to radiation and in cell growth control. | Q52521591 | ||
p53 induction, cell cycle checkpoints, and apoptosis in DNAPK-deficient scid mice. | Q53449267 | ||
Small peptides activate the latent sequence-specific DNA binding function of p53. | Q54601436 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 5923-5934 | |
P577 | publication date | 1997-10-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro | |
P478 | volume | 17 |
Q28203791 | A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1 |
Q90149996 | ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942 |
Q40613054 | Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2. |
Q35907026 | Applications of gene therapy for familial amyloidotic polyneuropathy |
Q42707122 | Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2-Cdk7 complex. |
Q24298631 | BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase |
Q27931743 | CTD kinase I is involved in RNA polymerase I transcription |
Q40272241 | Cdk9 phosphorylates p53 on serine 392 independently of CKII. |
Q33338375 | Characterization of a novel cardiac isoform of the cell cycle-related kinase that is regulated during heart failure |
Q40960693 | Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. |
Q38973176 | Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. |
Q35199554 | DNA damage induces phosphorylation of the amino terminus of p53 |
Q39640818 | DNA repair and transcriptional effects of mutations in TFIIH in Drosophila development |
Q64389076 | DNA signals for G2 checkpoint response in diploid human fibroblasts |
Q44487712 | Dephosphorylation of p53 during cell death by N-alpha-tosyl-L-phenylalanyl chloromethyl ketone |
Q33997846 | Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress |
Q73088400 | Dissociation of the recombination control and the sequence-specific transactivation function of P53 |
Q46408733 | Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells |
Q40932282 | Drug-induced apoptosis is delayed and reduced in XPD lymphoblastoid cell lines: possible role of TFIIH in p53-mediated apoptotic cell death |
Q64059258 | Efficacy of the novel CDK7 inhibitor QS1189 in mantle cell lymphoma |
Q24306430 | Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta |
Q41811880 | Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer |
Q34417108 | Genotoxic and non-genotoxic pathways of p53 induction |
Q73794909 | Human DNA repair genes |
Q36907227 | Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities |
Q52316521 | ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment. |
Q28388232 | Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates |
Q33967914 | Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. |
Q36073860 | Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression |
Q35857003 | Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest |
Q33807813 | Mechanisms of switching on p53: a role for covalent modification? |
Q24811971 | Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors |
Q33704559 | Molecular interaction map of the mammalian cell cycle control and DNA repair systems |
Q49964619 | Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding |
Q53422893 | Mutations in serines 15 and 20 of human p53 impair its apoptotic activity. |
Q36485499 | Non-p53 p53RE binding protein, a human transcription factor functionally analogous to P53. |
Q39292772 | PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway |
Q40277059 | Phosphorylation and gene expression of p53 are not affected in human cells exposed to 2.1425 GHz band CW or W-CDMA modulated radiation allocated to mobile radio base stations |
Q36012544 | Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 function |
Q34093159 | Phosphorylation in transcription: the CTD and more |
Q44513266 | Phosphorylation site interdependence of human p53 post-translational modifications in response to stress |
Q36527456 | Posttranslational phosphorylation of mutant p53 protein in tumor development |
Q40311425 | Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities. |
Q54075746 | RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells. |
Q42509472 | Reconstitution of recombinant TFIIH that can mediate activator-dependent transcription |
Q33892839 | Regulation of p53 stability and activity in response to genotoxic stress. |
Q37636014 | Regulation of p53--insights into a complex process |
Q34816680 | Regulation of transcription elongation by phosphorylation |
Q43915766 | SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression |
Q46302815 | Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis |
Q64234008 | Small molecule activators of the p53 response |
Q91738289 | TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer |
Q33552252 | TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression |
Q38008913 | TFIIH: when transcription met DNA repair. |
Q35210621 | Targeted gene repair -- in the arena |
Q46862330 | The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways. |
Q33923593 | The MAT1 cyclin-dependent kinase-activating kinase (CAK) assembly/targeting factor interacts physically with the MCM7 DNA licensing factor |
Q33771774 | The cellular response to p53: the decision between life and death |
Q40715337 | The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H. |
Q52319133 | The essential and multi-functional TFIIH complex. |
Q33832707 | The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation. |
Q42819038 | The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage. |
Q38336958 | The involvement of XPC protein in the cisplatin DNA damaging treatment-mediated cellular response. |
Q42454112 | The p53 tumor suppressor inhibits transcription of the TATA-less mouse DP1 promoter. |
Q34187832 | The p53 tumour suppressor protein |
Q36438161 | Transcription abnormalities potentiate apoptosis of normal human fibroblasts. |
Q33601019 | Transcription factor IIH: a key player in the cellular response to DNA damage |
Q37413761 | Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389 |
Q40827234 | Wild-type p53 inhibits protein kinase CK2 activity |
Q36538872 | hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage |
Q33632282 | p53 and the CNS: tumors and developmental abnormalities |
Q28210026 | p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex |
Q36163707 | p53: twenty five years understanding the mechanism of genome protection |
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