scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1016605663 |
P356 | DOI | 10.1038/SJ.ONC.1202964 |
P698 | PubMed publication ID | 10523858 |
P2093 | author name string | L Wiesmüller | |
C Dudenhöffer | |||
W Deppert | |||
M Kurth | |||
F Janus | |||
P2860 | cites work | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 |
p53 modulation of TFIIH–associated nucleotide excision repair activity | Q24336880 | ||
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner | Q24643993 | ||
BRCA1 regulates p53-dependent gene expression | Q24685083 | ||
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism | Q28245231 | ||
Oncogenic forms of p53 inhibit p53-regulated gene expression | Q28251120 | ||
p21 is a universal inhibitor of cyclin kinases | Q28257305 | ||
14-3-3sigma is a p53-regulated inhibitor of G2/M progression | Q28276061 | ||
Association of BRCA1 with Rad51 in mitotic and meiotic cells | Q28302118 | ||
p53 mutations in human cancers | Q28302973 | ||
Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos | Q28510071 | ||
Formation of stable p53 homotetramers and multiples of tetramers | Q44277113 | ||
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. | Q52528383 | ||
Cell-cycle control and its watchman. | Q53453500 | ||
p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction | Q64386856 | ||
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 | Q67521108 | ||
An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53 | Q67539546 | ||
A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation | Q71169980 | ||
p53 Protein exhibits 3'-to-5' exonuclease activity | Q71170481 | ||
Human p53 binds Holliday junctions strongly and facilitates their cleavage | Q73119545 | ||
DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53 | Q73615085 | ||
Signaling to p53: breaking the MDM2-p53 circuit | Q77430977 | ||
p53 oligomerization and DNA looping are linked with transcriptional activation | Q28639938 | ||
The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding | Q28639955 | ||
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Q29547697 | ||
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control | Q29616465 | ||
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53 | Q29618277 | ||
Targeted disruption of the Rad51 gene leads to lethality in embryonic mice | Q29618278 | ||
The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation | Q33846651 | ||
The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis | Q33888765 | ||
Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA. | Q33912006 | ||
Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation. | Q34055161 | ||
The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity | Q34252975 | ||
Inactivation of p53 results in high rates of homologous recombination | Q34426097 | ||
BRCA1 physically associates with p53 and stimulates its transcriptional activity. | Q34467604 | ||
Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. | Q34741387 | ||
p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. | Q34972350 | ||
p53 function and dysfunction | Q35721291 | ||
A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins | Q36122736 | ||
Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53. | Q36546016 | ||
Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells | Q36647653 | ||
p53 domains: structure, oligomerization, and transformation | Q36662699 | ||
Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing | Q36796242 | ||
Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus | Q38294071 | ||
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches | Q38294077 | ||
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein | Q38313694 | ||
Regulation of the specific DNA binding function of p53 | Q38324290 | ||
DNA bending is essential for the site-specific recognition of DNA response elements by the DNA binding domain of the tumor suppressor protein p53. | Q38345163 | ||
Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding | Q39444904 | ||
Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination | Q39575932 | ||
In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes | Q39873297 | ||
Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids | Q40021667 | ||
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro | Q40023550 | ||
Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells. | Q40043948 | ||
Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis | Q40647696 | ||
Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule | Q40665592 | ||
Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. | Q40792701 | ||
p53-catalyzed annealing of complementary single-stranded nucleic acids | Q40873109 | ||
Oligomerization is not essential for growth suppression by p53 in p53-deficient osteosarcoma Saos-2 cells | Q41121209 | ||
Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein | Q41121233 | ||
Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53 | Q42630918 | ||
Specific p53-DNA complexes contain an mdm2-related protein | Q42802655 | ||
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. | Q43918911 | ||
P433 | issue | 42 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5773-5784 | |
P577 | publication date | 1999-10-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Dissociation of the recombination control and the sequence-specific transactivation function of P53 | |
P478 | volume | 18 |
Q39644466 | A novel role for the Bcl-2 protein family: specific suppression of the RAD51 recombination pathway |
Q34572898 | A role for p53 in the frequency and mechanism of mutation |
Q31029673 | ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells |
Q64387631 | Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system |
Q34017186 | Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing. |
Q40720210 | Association of p53 and MSH2 with recombinative repair complexes during S phase |
Q39922858 | Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms. |
Q37973676 | Chromosome instability and deregulated proliferation: an unavoidable duo. |
Q34929930 | DNA double-strand break repair signalling: the case of RAD51 post-translational regulation. |
Q39675323 | DNA substrate dependence of p53-mediated regulation of double-strand break repair |
Q40439624 | Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination |
Q40480309 | Discriminatory suppression of homologous recombination by p53. |
Q32145744 | Evaluation of the genotoxicity of the phytoestrogen, coumestrol, in AHH-1 TK(+/-) human lymphoblastoid cells |
Q24803278 | Genetic Stabilization by p53 Involves Growth Regulatory and Repair Pathways |
Q28611377 | Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance |
Q40753297 | Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53. |
Q28646561 | Homologous recombinational repair of DNA ensures mammalian chromosome stability |
Q51604085 | Identification of genomic DNA sequences bound by mutant p53 protein (Gly245-->Ser) in vivo. |
Q36138010 | Influence of Human p53 on Plant Development |
Q53399551 | Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool. |
Q50954935 | One-Dimensional Search Dynamics of Tumor Suppressor p53 Regulated by a Disordered C-Terminal Domain. |
Q40593023 | Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells |
Q24680716 | Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional Analysis |
Q22121978 | Regulation and mechanisms of mammalian double-strand break repair |
Q33828413 | Regulation of MCP-1 chemokine transcription by p53 |
Q38308128 | Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53. |
Q39687338 | Role of tumor suppressor p53 domains in selective binding to supercoiled DNA. |
Q28288360 | The interaction of p53 with replication protein A mediates suppression of homologous recombination |
Q40570055 | The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase |
Q34935933 | The p53 network in lung carcinogenesis. |
Q36161258 | The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability |
Q28206425 | The processing of Holliday junctions by BLM and WRN helicases is regulated by p53 |
Q55223212 | Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin. |
Q44107661 | Wild-type p53 inhibits replication-associated homologous recombination |
Q81554284 | Wild-type p53 stimulates homologous recombination upon sequence-specific binding to the ribosomal gene cluster repeat |
Q38307731 | p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core |
Q36210348 | p53 Specifically Binds Triplex DNA In Vitro and in Cells |
Q40738842 | p53 and recombination intermediates: role of tetramerization at DNA junctions in complex formation and exonucleolytic degradation |
Q40544871 | p53 differentially inhibits cell growth depending on the mechanism of telomere maintenance |
Q36423948 | p53 in recombination and repair |
Q39367978 | p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation |
Q40344795 | p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene |
Q42443549 | p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair |
Q37126273 | p53 suppresses hyper-recombination by modulating BRCA1 function |
Q36028209 | p53: traffic cop at the crossroads of DNA repair and recombination |