Intercellular adhesion, signalling and the cytoskeleton

scientific article (publication date: April 2002)

Intercellular adhesion, signalling and the cytoskeleton is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P6179Dimensions Publication ID1053065489
P356DOI10.1038/NCB0402-E101
P3181OpenCitations bibliographic resource ID3697247
P698PubMed publication ID11944044
P5875ResearchGate publication ID11422606

P50authorElaine FuchsQ516846
P2093author name stringColin Jamora
P2860cites workCasein kinase I phosphorylates and destabilizes the beta-catenin degradation complexQ24532403
LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacityQ24548041
Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisionsQ24550770
Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expressionQ24644611
Making a connection: direct binding between keratin intermediate filaments and desmosomal proteinsQ24651318
Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivoQ24651534
Regulation of cadherin adhesive activityQ24669932
Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin FilamentsQ24678389
Defining the interactions between intermediate filaments and desmosomesQ24680223
An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3Q24682973
An epidermal plakin that integrates actin and microtubule networks at cellular junctionsQ24685978
The LIM domain: regulation by associationQ28137861
Integrin signalingQ28142010
Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-cateninQ28143737
N-Cadherin, a cell adhesion molecule involved in establishment of embryonic left-right asymmetryQ28144250
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skinQ28190343
Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skinQ28203751
The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobinQ28205780
Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkageQ28292286
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heartQ28293128
An alpha-E-catenin gene trap mutation defines its function in preimplantation developmentQ28303127
Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctionsQ28366225
Desmoplakin is essential in epidermal sheet formationQ28587535
E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent MannerQ28972449
Wnt signaling: a common theme in animal developmentQ29547527
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1Q29614379
A causal role for E-cadherin in the transition from adenoma to carcinomaQ29616122
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasionQ29616467
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skinQ29616492
Molecular mechanisms controlling actin filament dynamics in nonmuscle cellsQ29616514
Directed actin polymerization is the driving force for epithelial cell-cell adhesionQ29618861
The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expressionQ30175138
Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptorQ30420086
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src geneQ30450407
Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial primingQ30798313
Casein kinase 2associates with and phosphorylates DishevelledQ33886745
Dynamic actin-based epithelial adhesion and cell matching during Drosophila dorsal closure.Q33927041
Formation of two-dimensional complexes of F-actin and crosslinking proteins on lipid monolayers: demonstration of unipolar alpha-actinin-F-actin crosslinkingQ34018879
Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeletonQ34112824
Actin-based motility: stop and go with Ena/VASP proteinsQ34214319
Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryosQ34292991
New aspects of Wnt signaling pathways in higher vertebratesQ34353150
Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.Q34360639
At the roots of a never-ending cycle.Q34434895
Deconstructing desmoplakinQ34487375
JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in DrosophilaQ35170915
E-cadherin null mutant embryos fail to form a trophectoderm epitheliumQ35691712
The secret life of the hair follicleQ36016867
Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherinQ36233814
Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctionsQ36236491
Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in XenopusQ36236595
Lateral dimerization is required for the homophilic binding activity of C-cadherinQ36237591
Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasisQ36255369
Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent proteinQ36255689
Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibodyQ36255704
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgarisQ36262044
Precocious mammary gland development in P-cadherin-deficient mice.Q36274361
Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiationQ36294155
Plakoglobin suppresses epithelial proliferation and hair growth in vivoQ36328372
Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary glandQ36360340
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesionQ36534670
Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexesQ36672550
Frizzled-7 signalling controls tissue separation during Xenopus gastrulationQ38295420
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions.Q38301815
Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesionQ38315484
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinaseQ38330900
Decreased expression of catenins (alpha and beta), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomasQ38458462
Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: implications on early patterning and morphogenesisQ39749608
Desmosomal adhesion regulates epithelial morphogenesis and cell positioningQ40782521
Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells.Q40844760
Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cellsQ40937421
Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cellsQ41089132
Zyxin: zinc fingers at sites of cell adhesionQ41658428
Molecular and functional analysis of cadherin-based adherens junctionsQ41689344
E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activityQ41990554
Adherens junctions inhibit asymmetric division in the Drosophila epitheliumQ42499987
Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineageQ42516585
Dynein binds to beta-catenin and may tether microtubules at adherens junctions.Q43754950
E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contactsQ43823908
FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive StreakQ52127589
Morphogenesis.Q52179410
Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.Q52550758
Cadherin-mediated regulation of microtubule dynamicsQ57974921
Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing systemQ71019227
E-cadherin-mediated cell-cell attachment activates Cdc42Q74198219
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P304page(s)E101-8
P577publication date2002-04-01
P1433published inNature Cell BiologyQ1574111
P1476titleIntercellular adhesion, signalling and the cytoskeleton
P478volume4

Reverse relations

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Q43204475Real-time monitoring of membrane cholesterol reveals new insights into epidermal differentiation
Q35580804Recruitment of β-catenin to N-cadherin is necessary for smooth muscle contraction
Q30432337Regulation of cell shape, wing hair initiation and the actin cytoskeleton by Trc/Fry and Wts/Mats complexes
Q27301310Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis
Q36995391Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium.
Q35875579Role of subtilisin-like convertases in cadherin processing or the conundrum to stall cadherin function by convertase inhibitors in cancer therapy
Q39279718SERCA2 dysfunction in Darier disease causes endoplasmic reticulum stress and impaired cell-to-cell adhesion strength: rescue by Miglustat
Q28730053Selective activation of p120ctn-Kaiso signaling to unlock contact inhibition of ARPE-19 cells without epithelial-mesenchymal transition
Q38160893Signaling and mechanical roles of E-cadherin.
Q38229109Signaling pathways in anchoring junctions of epithelial cells: cell-to-cell and cell-to-extracellular matrix interactions.
Q24309031Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
Q40252264Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz
Q33886474Stroma regulates increased epithelial lateral cell adhesion in 3D culture: a role for actin/cadherin dynamics
Q39520127Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium
Q36983434Structure and function of desmosomes
Q40171928Suppression of keratinocyte stratification by a dominant negative JunB mutant without blocking cell proliferation
Q45095132Surface mechanics mediate pattern formation in the developing retina
Q51545946Sustainable fabrication of micro-structured lab-on-a-chip.
Q44801097Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes
Q33916238TGF-β suppresses β-catenin-dependent tolerogenic activation program in dendritic cells.
Q28586464Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality
Q37190358Temporal modulation of β-catenin signaling by multicellular aggregation kinetics impacts embryonic stem cell cardiomyogenesis
Q35006864Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour).
Q27316057The Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamics
Q30429717The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex
Q44566221The PI 3-kinase-Rac-p38 MAP kinase pathway is involved in the formation of signet-ring cell carcinoma
Q36315901The Rap GTPase activator Drosophila PDZ-GEF regulates cell shape in epithelial migration and morphogenesis
Q34688333The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion.
Q37398477The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cells
Q28244055The calpain system is involved in the constitutive regulation of beta-catenin signaling functions
Q41966646The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye
Q24815230The complexity of anatomical systems
Q89982470The differential response of the chicken trachea to chronic infection with virulent Mycoplasma gallisepticum strain Ap3AS and Vaxsafe MG (strain ts-304) - a transcriptional profile
Q35126974The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites
Q26859120The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue
Q35348787The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling
Q46032800The premetazoan ancestry of cadherins.
Q39614262The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model
Q35841003The receptor tyrosine phosphatase Lar regulates adhesion between Drosophila male germline stem cells and the niche
Q38364407The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle
Q30375564The role of the cytoskeleton in the formation of gap junctions by Connexin 30.
Q41545568The squid ink polysaccharides protect tight junctions and adherens junctions from chemotherapeutic injury in the small intestinal epithelium of mice
Q30409921The surprising dynamics of scaffolding proteins.
Q28512337The transcriptional repressor Glis2 is a novel binding partner for p120 catenin
Q30613021The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion
Q36764938Tie2 Regulates Tumor Metastasis of Oral Squamous Cell Carcinomas.
Q34103375Tissue architecture: the ultimate regulator of breast epithelial function
Q28586650Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells
Q42497872Transcriptional profiling of epidermal differentiation
Q33938454Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathway
Q46138455Transient dynamic actin cytoskeletal change stimulates the osteoblastic differentiation.
Q37614832Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation
Q33641786Tumor necrosis factor-α confers cardioprotection through ectopic expression of keratins K8 and K18.
Q40015675Tyrosine Phosphorylation of Plakoglobin Causes Contrary Effects on Its Association with Desmosomes and Adherens Junction Components and Modulates β-Catenin-Mediated Transcription
Q39249967Vasoactive intestinal peptide induces oxidative stress and suppresses metastatic potential in human clear cell renal cell carcinoma
Q34510738WNT2 regulates DNA synthesis in mouse granulosa cells through beta-catenin
Q36305544Winding through the WNT pathway during cellular development and demise
Q42060328Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells
Q37080180Wnt signaling in lung organogenesis
Q35741011Working out the strength and flexibility of desmosomes
Q30479922aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development
Q37620912c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
Q28277153miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration
Q42198504p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis
Q36210483β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition
Q36362945β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia.
Q90389157β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea
Q97530731β-catenin S45F mutation results in apoptotic resistance