scholarly article | Q13442814 |
P819 | ADS bibcode | 2018NatCo...9.5390P |
P356 | DOI | 10.1038/S41467-018-07812-8 |
P932 | PMC publication ID | 6300608 |
P698 | PubMed publication ID | 30568254 |
P50 | author | Vaibhav B. Patel | Q42402068 |
Dong Fan | Q90648110 | ||
Mousumi Hazra | Q90648112 | ||
Pavel Zhabyeyev | Q60321267 | ||
Bart Vanhaesebroeck | Q64481959 | ||
Christopher Mcculloch | Q88585534 | ||
P2093 | author name string | Pu Zhang | |
Gavin Y Oudit | |||
W Glen Pyle | |||
Ratnadeep Basu | |||
Zamaneh Kassiri | |||
John F Dawson | |||
Faqi Wang | |||
Manish Paul | |||
Xueyi Chen | |||
Saumya Shah | |||
Saugata Hazra | |||
Brent A McLean | |||
P2860 | cites work | Nebulette Mutations Are Associated With Dilated Cardiomyopathy and Endocardial Fibroelastosis | Q24303466 |
Cardiac regulation by phosphoinositide 3-kinases and PTEN | Q24317248 | ||
2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines | Q26864648 | ||
PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes | Q27321455 | ||
Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin | Q27656937 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading | Q27860652 | ||
Comparative protein modelling by satisfaction of spatial restraints | Q27860866 | ||
GROMACS: fast, flexible, and free | Q27860998 | ||
Intercellular adhesion, signalling and the cytoskeleton | Q28214252 | ||
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin | Q28300043 | ||
Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure | Q28303455 | ||
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells | Q28506999 | ||
Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress | Q28590326 | ||
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation | Q28594707 | ||
Essential dynamics of proteins | Q29616843 | ||
Evaluation of comparative protein modeling by MODELLER | Q29617322 | ||
Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy | Q30439445 | ||
Membrane cytoskeleton: PIP(2) pulls the strings. | Q33912799 | ||
Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy | Q34097448 | ||
Truncations of titin causing dilated cardiomyopathy. | Q34254460 | ||
Cardiac plasticity | Q34764732 | ||
Ras, Akt, and mechanotransduction in the cardiac myocyte | Q35606137 | ||
Molecular genetics and genomics of heart failure | Q35936390 | ||
Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker | Q35956572 | ||
The conserved phosphoinositide 3-kinase pathway determines heart size in mice | Q36246110 | ||
ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity | Q36392875 | ||
Genetic mutations and mechanisms in dilated cardiomyopathy | Q36497170 | ||
2-Deoxyadenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy | Q36699259 | ||
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. | Q36751486 | ||
Dynamic localization of G-actin during membrane protrusion in neuronal motility. | Q37016353 | ||
Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes | Q37036350 | ||
Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis | Q37101896 | ||
Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. | Q37310459 | ||
Uncoupling between enhanced excitation-contraction coupling and the response to heart disease: lessons from the PI3Kγ knockout murine model. | Q37833231 | ||
Intercellular and extracellular mechanotransduction in cardiac myocytes | Q37857739 | ||
Multifunctional roles of gelsolin in health and diseases | Q38034125 | ||
Mechanisms and Functions of Vinculin Interactions with Phospholipids at Cell Adhesion Sites | Q38265394 | ||
Identification of a phosphatidylinositol 4,5-bisphosphate-binding site in chicken skeletal muscle alpha-actinin | Q38361897 | ||
Molecules in medicine mini-review: isoforms of PI3K in biology and disease | Q38666875 | ||
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways | Q39750571 | ||
Regulation of intercellular adhesion strength in fibroblasts | Q40537082 | ||
Isoform-selective induction of human p110δ PI3K expression by TNFα: identification of a new and inducible PIK3CD promoter | Q41789259 | ||
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. | Q41791633 | ||
MinActionPath: maximum likelihood trajectory for large-scale structural transitions in a coarse-grained locally harmonic energy landscape | Q41808112 | ||
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. | Q42447268 | ||
FAK, PIP5KIgamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin | Q42795993 | ||
Comparative molecular dynamics simulation studies for determining factors contributing to the thermostability of chemotaxis protein "CheY". | Q43018766 | ||
Cadherins mediate intercellular mechanical signaling in fibroblasts by activation of stretch-sensitive calcium-permeable channels | Q43683616 | ||
The progression from hypertension to congestive heart failure | Q43812016 | ||
Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes | Q44477120 | ||
Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction | Q45879808 | ||
Protein misfolding and amyloid formation for the peptide GNNQQNY from yeast prion protein Sup35: simulation by reaction path annealing | Q46492576 | ||
Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments. | Q46983155 | ||
Gelsolin and cardiac myocyte apoptosis: a new target in the treatment of postinfarction remodeling | Q48024113 | ||
Advanced heart failure treated with continuous-flow left ventricular assist device | Q48952442 | ||
Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD Working Group. | Q51010198 | ||
PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart. | Q51308924 | ||
Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. | Q51772425 | ||
On the convergence of the conformational coordinates basis set obtained by the essential dynamics analysis of proteins' molecular dynamics simulations. | Q52206949 | ||
Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice. | Q53173814 | ||
Novel Dominant-Negative Mutation in Cardiac Troponin I Causes Severe Restrictive Cardiomyopathy. | Q53520024 | ||
Exogenous gelsolin binds to sarcomeric thin filaments without severing | Q54187969 | ||
Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress | Q57184516 | ||
Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice | Q58211733 | ||
Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory protein | Q59064148 | ||
Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate | Q59072772 | ||
Dependence of fibroblast migration on actin severing activity of gelsolin | Q71246159 | ||
Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart | Q73015364 | ||
Gelsolin binding to phosphatidylinositol 4,5-bisphosphate is modulated by calcium and pH | Q73575375 | ||
The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway | Q79248092 | ||
A high-throughput assay shows that DNase-I binds actin monomers and polymers with similar affinity | Q80070026 | ||
ADP-Ribosylation of Cross-Linked Actin Generates Barbed-End Polymerization-Deficient F-Actin Oligomers | Q84959303 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cytoskeleton | Q154626 |
P304 | page(s) | 5390 | |
P577 | publication date | 2018-12-19 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease | |
P478 | volume | 9 |
Q91660243 | Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure |
Q90124031 | Nicotinic acid affects cytoskeleton remodeling via increasing the activity of gelsolin |
Q89459605 | PI3K inhibitors in thrombosis and cardiovascular disease |
Q64075558 | PI3Kα Pathway Inhibition With Doxorubicin Treatment Results in Distinct Biventricular Atrophy and Remodeling With Right Ventricular Dysfunction |
Q91606069 | PI3Kα in cardioprotection: Cytoskeleton, late Na+ current, and mechanism of arrhythmias |
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