Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells

scientific article (publication date: 6 December 2002)

Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-291X(02)02670-0
P698PubMed publication ID12445828
P5875ResearchGate publication ID11022903

P50authorHiroyasu NakanoQ55277402
Norihiro HaradaQ73561892
P2093author name stringHideo Yagita
Ko Okumura
Yoshinosuke Fukuchi
Masafumi Nakayama
P2860cites workA novel TNF receptor family member binds TWEAK and is implicated in angiogenesisQ24291951
Identification of a ligand for the death-domain-containing receptor Apo3Q24310256
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomasQ24681487
Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodiesQ24803611
Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3)Q28138623
TWEAK induces angiogenesis and proliferation of endothelial cellsQ28139175
Multiple pathways of TWEAK-induced cell deathQ28214614
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosisQ28257134
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinaseQ28270530
Apoptosis by death factorQ28304002
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
Activators and target genes of Rel/NF-kappaB transcription factorsQ29547882
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa BQ29618194
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systemsQ33876783
Signaling by the TNF receptor superfamily and T cell homeostasisQ34078765
Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicityQ36369095
Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimersQ38299782
TWEAK can induce cell death via endogenous TNF and TNF receptor 1.Q38323407
Current and future clinical applications of interferon-gamma in host antimicrobial defenseQ40924880
Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitmentQ41036449
Cytokine regulation of endothelial cell function: from molecular level to the bedsideQ41472342
Cytokines in the induction and expression of T-cell-mediated granuloma formation and protection in the murine model of listeriosisQ41603425
A simple, non-chromatographic purification procedure for monoclonal antibodies. Isolation of monoclonal antibodies against cytochrome P450 isozymesQ69062667
Conserved Glu318 at the cytochrome P450 1A2 distal site is crucial in the nitric oxide complex stabilityQ71058638
TWEAK stimulation of astrocytes and the proinflammatory consequencesQ74280324
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
endotheliumQ111140
P304page(s)488-493
P577publication date2002-12-01
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titlePro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells
P478volume299

Reverse relations

cites work (P2860)
Q38123074A further TWEAK to multiple sclerosis pathophysiology
Q35083662A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia
Q36690605Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL
Q39704685Antiangiogenic activity of ursolic acid.
Q30724766BAFF, APRIL, TWEAK, BCMA, TACI and Fn14 proteins are related to human glioma tumor grade: immunohistochemistry and public microarray data meta-analysis
Q35954775Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD.
Q28592715Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies
Q26995211Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damage
Q42776466Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium
Q27678102Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding
Q85167906Direct targeting of fibroblast growth factor-inducible 14 protein protects against renal ischemia reperfusion injury
Q36546646Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb.
Q28211919Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth
Q37071856Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis.
Q37724036Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice
Q40555106Involvement of GSK-3beta in TWEAK-mediated NF-kappaB activation
Q39778302Proinflammatory effect of TWEAK/Fn14 interaction in human retinal pigment epithelial cells
Q54571749Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts.
Q34291063Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression
Q53540861Relationship of serum TWEAK level to cytokine level, disease activity, and response to anti-TNF treatment in patients with rheumatoid arthritis.
Q38021183Role of TWEAK in lupus nephritis: a bench-to-bedside review
Q38317752Role of strain differences on host resistance and the transcriptional response of macrophages to infection with Yersinia enterocolitica.
Q44740069Serum TNF-related and weak inducer of apoptosis levels in septic shock patients
Q37415728Soluble TWEAK plasma levels as a novel biomarker of endothelial function in patients with chronic kidney disease
Q46354917Soluble TWEAK plasma levels increase after renal transplantation and associate with the improvement of endothelial function
Q34993747Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis
Q39406226TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation
Q28749137TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21
Q37697186TWEAK activation of the non-canonical NF-κB signaling pathway differentially regulates melanoma and prostate cancer cell invasion
Q34206359TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus
Q35092962TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.
Q37295055TWEAK and Fn14 in the Neurovascular Unit
Q37722596TWEAK as a target for therapy in systemic lupus erythematosus.
Q24553352TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules
Q41870284TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice
Q38885125TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells.
Q31148506TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.
Q33860715TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis.
Q40641517TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor
Q27318227TWEAK promotes peritoneal inflammation
Q57245504TWEAK-Fn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells
Q42361200TWEAK/Fn14 Activation Participates in Skin Inflammation
Q37494039TWEAK/Fn14 Axis: A Promising Target for the Treatment of Cardiovascular Diseases.
Q53382894TWEAK/Fn14 activation induces keratinocyte proliferation under psoriatic inflammation.
Q35605699TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells
Q38668064TWEAK/Fn14 signaling in tumors
Q38177788TWEAK: A New Player in Obesity and Diabetes.
Q38991116Targeting STOX1 in the therapy of preeclampsia
Q94418605The Evaluation of Serum Tumor Necrosis Factor-Like Weak Inducer of Apoptosis, Interleukin-6, Fetuin-A, Homeostatic Model Assessment-Insulin Resistance, and Insulin Levels in Rheumatoid Arthritis Patients in Clinical Remission
Q40677513The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation
Q37135363The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting
Q36666882The cytokine TWEAK modulates renal tubulointerstitial inflammation
Q35850469The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system
Q34171150The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain
Q38638020The role of tumor necrosis factor-like weak inducer of apoptosis in atherosclerosis via its two different receptors
Q35450066The tumor necrosis factor superfamily of cytokines in the inflammatory myopathies: potential targets for therapy.
Q28299334The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression
Q36230448Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer
Q89696547Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK)/Fibroblast Growth Factor-Inducible 14 (Fn14) Axis in Cardiovascular Diseases: Progress and Challenges
Q63988279Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration
Q34348370Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death
Q37980604Tumor necrosis factor-like weak inducer of apoptosis and its potential roles in lupus nephritis
Q42250250Tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 are expressed in urticarial vasculitis
Q48708341Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappa B pathway activation.
Q35026182Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice.
Q53489723Tumor necrosis factor-like weak inducer of apoptosis regulates the phenotype and cytotoxic activity of goat uterine natural killer cells.
Q39506124Tumour necrosis factor-like weak inducer of apoptosis (TWEAK), an important mediator of endothelial inflammation, is associated with the pathogenesis of Henoch-Schonlein purpura
Q40453290Tweak induces mammary epithelial branching morphogenesis.
Q35893298Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia
Q50988060Tweak up-regulates endothelin-1 system in mouse and human endothelial cells.
Q37453911Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study.

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