| scholarly article | Q13442814 |
| P50 | author | Gerald Cohen | Q124330644 |
| P2093 | author name string | Michael Butterworth | |
| Xiao-Ming Sun | |||
| Shawn B Bratton | |||
| Marion MacFarlane | |||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | mitochondrion | Q39572 |
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 11345-51 | |
| P577 | publication date | 2002-03-29 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein | |
| P478 | volume | 277 |
| Q39971508 | A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma |
| Q38361116 | Amyloid-beta induces Smac release via AP-1/Bim activation in cerebral endothelial cells. |
| Q36092837 | Apoptosis of HIV-specific CD8+ T cells: an HIV evasion strategy. |
| Q35092230 | Apoptotic signaling cascades. |
| Q39625446 | Aucubin modulates Bcl-2 family proteins expression and inhibits caspases cascade in H₂O₂-induced PC12 cells |
| Q28564542 | BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy |
| Q55451018 | Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps. |
| Q45249980 | Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w. |
| Q35642101 | Bid-independent mitochondrial activation in tumor necrosis factor alpha-induced apoptosis and liver injury |
| Q44598662 | Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1. |
| Q47316430 | Bistability analyses of a caspase activation model for receptor-induced apoptosis |
| Q44780691 | CDDO induces apoptosis via the intrinsic pathway in lymphoid cells. |
| Q44066922 | Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia |
| Q40462602 | Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines. |
| Q40569376 | Caspase activation inhibits proteasome function during apoptosis |
| Q37446194 | Caspase-9 activation by the apoptosome is not required for fas-mediated apoptosis in type II Jurkat cells |
| Q46500208 | Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis |
| Q37003894 | Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes |
| Q46463388 | Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1. |
| Q47100889 | Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10. |
| Q44292870 | Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells |
| Q39935218 | Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells |
| Q37601161 | Death ligand concentration and the membrane proximal signaling module regulate the type 1/type 2 choice in apoptotic death signaling |
| Q23916638 | Dependence of reactive oxygen species and FLICE inhibitory protein on lipofectamine-induced apoptosis in human lung epithelial cells |
| Q40564201 | Differences in the expression of apoptotic proteins in Burkitt's lymphoma cell lines: potential models for screening apoptosis-inducing agents |
| Q43902939 | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells |
| Q40011719 | Double inhibition of XIAP and Bcl-2 axis is beneficial for retrieving sensitivity of renal cell cancer to apoptosis |
| Q28574114 | Dynamic changes of the anti- and pro-apoptotic proteins Bcl-w, Bcl-2, and Bax with Smac/Diablo mitochondrial release after photothrombotic ring stroke in rats |
| Q35910540 | Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates |
| Q39115945 | Effects of different sources and levels of zinc on H2O2-induced apoptosis in IEC-6 cells |
| Q40596826 | Enhancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death |
| Q35108258 | Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins |
| Q58419047 | Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds |
| Q28204338 | Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway |
| Q36139561 | Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells |
| Q35705510 | Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold |
| Q39396823 | Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition |
| Q53627345 | Heat shock induces apoptosis independently of any known initiator caspase-activating complex. |
| Q48003529 | Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. |
| Q35371553 | High cell surface death receptor expression determines type I versus type II signaling |
| Q40479108 | Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. |
| Q29619844 | IAP proteins: blocking the road to death's door |
| Q44185861 | Id2 expression during apoptosis and satellite cell activation in unloaded and loaded quail skeletal muscles |
| Q37577474 | Implication of transcriptional repression in compound C-induced apoptosis in cancer cells |
| Q40195158 | Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells |
| Q42089513 | Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis |
| Q53473485 | Interaction with XIAP prevents full caspase-3/-7 activation in proliferating human T lymphocytes. |
| Q44649501 | Intracellular determination of activated caspases (IDAC) by flow cytometry using a pancaspase inhibitor labeled with FITC |
| Q44357715 | Low probability activation of Bax/Bak can induce selective killing of cancer cells by generating heterogeneity in apoptosis |
| Q35682077 | Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis |
| Q21563509 | Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability |
| Q40094198 | Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. |
| Q24302312 | Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells |
| Q36495968 | MicroRNAs: recently discovered key regulators of proliferation and apoptosis in animal cells : Identification of miRNAs regulating growth and survival |
| Q37060283 | Minimal systems analysis of mitochondria-dependent apoptosis induced by cisplatin |
| Q38235124 | Mitochondria-mediated apoptosis in mammals |
| Q51289590 | Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. |
| Q28474253 | Modeling a snap-action, variable-delay switch controlling extrinsic cell death |
| Q30544925 | Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging |
| Q37537255 | Modulatory effect of high saturated fat diet-induced metabolic disturbances on angiogenic response in hepatocyte RXRα knockout mice |
| Q37679250 | Monte carlo study elucidates the type 1/type 2 choice in apoptotic death signaling in healthy and cancer cells |
| Q44445731 | N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression |
| Q35092234 | Natural cellular inhibitors of caspases |
| Q43280940 | Neuroprotective effect of baicalein on hydrogen peroxide-mediated oxidative stress and mitochondrial dysfunction in PC12 cells |
| Q47793589 | Nonapoptotic functions of Fas/CD95 in the immune response |
| Q40470939 | Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes. |
| Q36285964 | On the TRAIL of a new therapy for leukemia. |
| Q36102304 | Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis. |
| Q39847732 | Phenylarsine oxide interferes with the death inducing signaling complex and inhibits tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis |
| Q44905141 | Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation |
| Q37085837 | Promotion of Fas-mediated apoptosis in Type II cells by high doses of hepatocyte growth factor bypasses the mitochondrial requirement |
| Q39698787 | Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation |
| Q44550507 | Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling |
| Q33807797 | Quantitative analysis of pathways controlling extrinsic apoptosis in single cells |
| Q36059491 | Recent advances in understanding the cell death pathways activated by anticancer therapy |
| Q35118566 | Regulation of apoptosis: the ubiquitous way |
| Q73251268 | Regulation of apoptotic signaling pathways in hepatocytes in vivo |
| Q38034651 | Regulation of the human TRAIL gene. |
| Q38052312 | Rejuvenating Bi(d)ology |
| Q34355580 | Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels. |
| Q36762412 | Resistance to HSP90 inhibition involving loss of MCL1 addiction. |
| Q35751450 | Response to bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores |
| Q35299643 | Role of caspases in renal tubular epithelial cell injury |
| Q40185447 | Role of cytochrome C in apoptosis: increased sensitivity to tumor necrosis factor alpha is associated with respiratory defects but not with lack of cytochrome C release |
| Q35117678 | Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra |
| Q39714230 | Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation |
| Q40399595 | Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. |
| Q40501514 | Stimulation of Fas agonistic antibody-mediated apoptosis by heparin-like agents suppresses Hsp27 but not Bcl-2 protective activity. |
| Q34360719 | Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes |
| Q39314142 | TRAIL resistance in human neuroblastoma SK-N-AS cells is dependent on protein kinase C and involves inhibition of caspase-3 proteolytic processing |
| Q48554413 | Temporal and region-dependent changes in muscarinic M4 receptors in the hippocampus and entorhinal cortex of adrenalectomized rats |
| Q50104142 | Thalidomide potentiates etoposide-induced apoptosis in murine neuroblastoma through suppression of NF-κB activation. |
| Q35031256 | The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions |
| Q35561587 | The CD95 type I/type II model |
| Q93023559 | The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines |
| Q51294973 | Theoretical Analysis of Fas Ligand-Induced Apoptosis with an Ordinary Differential Equation Model. |
| Q28190313 | To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis |
| Q40688728 | Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release. |
| Q40393121 | Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma |
| Q33208795 | Type I and type II reactions in TRAIL-induced apoptosis -- results from dose-response studies. |
| Q24563793 | Upstream regulatory role for XIAP in receptor-mediated apoptosis |
| Q44104444 | XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis |
| Q36642611 | microRNA-1301-mediated inhibition of tumorigenesis |
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