| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1022268671 |
| P356 | DOI | 10.1038/SJ.LEU.2403496 |
| P698 | PubMed publication ID | 15356645 |
| P5875 | ResearchGate publication ID | 8356695 |
| P2093 | author name string | Han J | |
| Wang GQ | |||
| Fang B | |||
| Rabinowich H | |||
| Goldstein LA | |||
| Gastman BR | |||
| Rabinovitz A | |||
| P2860 | cites work | An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 | Q22009407 |
| Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak | Q24290999 | ||
| SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) | Q24292189 | ||
| Structural basis of IAP recognition by Smac/DIABLO | Q27629148 | ||
| Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis | Q28140307 | ||
| Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8 | Q28189969 | ||
| Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction | Q28199278 | ||
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis | Q28204205 | ||
| Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein | Q28215991 | ||
| Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria | Q28218562 | ||
| Death receptors: signaling and modulation | Q28280897 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis | Q28512377 | ||
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues | Q28512628 | ||
| Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death | Q28586301 | ||
| VDAC2 inhibits BAK activation and mitochondrial apoptosis | Q28594000 | ||
| A unified model for apical caspase activation | Q28609101 | ||
| Insights into the regulatory mechanism for caspase-8 activation | Q28609102 | ||
| IAP proteins: blocking the road to death's door | Q29619844 | ||
| Role of BAX in the apoptotic response to anticancer agents | Q31523620 | ||
| Apoptosis control by death and decoy receptors | Q33597389 | ||
| Safety and antitumor activity of recombinant soluble Apo2 ligand | Q33855449 | ||
| Apoptotic pathways: paper wraps stone blunts scissors | Q33993406 | ||
| Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. | Q34139321 | ||
| Cell death regulation by the mammalian IAP antagonist Diablo/Smac. | Q34543760 | ||
| Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression | Q35663874 | ||
| Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax. | Q36368546 | ||
| Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells | Q36376406 | ||
| TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. | Q39753656 | ||
| Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins | Q40622338 | ||
| A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells | Q40645774 | ||
| A role for mitochondrial Bak in apoptotic response to anticancer drugs | Q40793451 | ||
| Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. | Q40938605 | ||
| Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. | Q40975748 | ||
| BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability | Q41043279 | ||
| Evaluation of GAL4/TATA in vivo. Induction of transgene expression by adenovirally mediated gene codelivery | Q41056260 | ||
| Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases | Q42657216 | ||
| Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis. | Q43627756 | ||
| Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. | Q43903493 | ||
| Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ | Q44129457 | ||
| A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro | Q44559968 | ||
| A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax. | Q45865366 | ||
| Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo | Q48548442 | ||
| N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death. | Q51074743 | ||
| Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells. | Q51695744 | ||
| Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. | Q53445992 | ||
| Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors. | Q54027478 | ||
| Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. | Q55473556 | ||
| Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity. | Q55476497 | ||
| Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis | Q60188645 | ||
| Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis | Q73700378 | ||
| Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions | Q73704158 | ||
| P433 | issue | 10 | |
| P921 | main subject | leukemia | Q29496 |
| P304 | page(s) | 1671-1680 | |
| P577 | publication date | 2004-10-01 | |
| P1433 | published in | Leukemia | Q6534498 |
| P1476 | title | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells | |
| P478 | volume | 18 |
| Q39965483 | ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis |
| Q33295311 | Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak. |
| Q34168023 | BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells |
| Q28546869 | Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound |
| Q39935218 | Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells |
| Q37832083 | Combined modality therapy with TRAIL or agonistic death receptor antibodies. |
| Q42009519 | Controlling TRAIL-mediated caspase-3 activation. |
| Q41351871 | Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats |
| Q33991174 | Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage |
| Q40135330 | Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines |
| Q40191065 | Downregulation of Bid is associated with PKCepsilon-mediated TRAIL resistance |
| Q42254718 | Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells |
| Q40316401 | Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis |
| Q35223910 | Killing of resistant cancer cells with low Bak by a combination of an antimesothelin immunotoxin and a TRAIL Receptor 2 agonist antibody |
| Q46078718 | Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. |
| Q35643014 | Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells |
| Q39239250 | TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis |
| Q35018048 | Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection |
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