| Q40427989 | 14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients |
| Q45980723 | 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. |
| Q40063118 | 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether induces growth inhibition and apoptosis in MCF-7 human breast cancer cells |
| Q41823335 | 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells |
| Q40332078 | 4-hydroxynonenal and cell cycle |
| Q42168969 | 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-alpha-mediated apoptosis. |
| Q39736728 | 5,7,3'-trihydroxy-3,4'-dimethoxyflavone-induced cell death in human leukemia cells is dependent on caspases and activates the MAPK pathway |
| Q28201937 | 5-Fluorouracil: mechanisms of action and clinical strategies |
| Q37308971 | 9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells |
| Q40784934 | A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line |
| Q51746668 | A bibenzyl from Dendrobium ellipsophyllum induces apoptosis in human lung cancer cells. |
| Q77649645 | A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes |
| Q79961073 | A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells |
| Q39810628 | A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice |
| Q39932213 | A mitochondriotropic derivative of quercetin: a strategy to increase the effectiveness of polyphenols |
| Q34956163 | A new challenge for successful immunotherapy by tumors that are resistant to apoptosis: two complementary signals to overcome cross-resistance |
| Q93064725 | A non-death function of the mitochondrial apoptosis apparatus in immunity |
| Q39652000 | A novel 7‐azaisoindigo derivative‐induced cancer cell apoptosis and mitochondrial dysfunction mediated by oxidative stress |
| Q37536525 | A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer |
| Q39819752 | A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes |
| Q36845372 | A novel aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment |
| Q40330460 | A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis |
| Q39210557 | A recombined protein (rSj16) derived from Schistosoma japonicum induces cell cycle arrest and apoptosis of murine myeloid leukemia cells |
| Q40793451 | A role for mitochondrial Bak in apoptotic response to anticancer drugs |
| Q37272156 | A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor |
| Q44380190 | A short, stereocontrolled, and practical synthesis of alpha-methylomuralide, a potent inhibitor of proteasome function |
| Q80439910 | A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas |
| Q33762787 | A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death |
| Q39129479 | ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis |
| Q40536323 | AMP-activated protein kinase couples 3-bromopyruvate-induced energy depletion to apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins |
| Q49247817 | APTM, a Thiophene Heterocyclic Compound, Inhibits Human Colon Cancer HCT116 Cell Proliferation Through p53-Dependent Induction of Apoptosis |
| Q24305337 | ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway |
| Q58119442 | ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells |
| Q33861908 | Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase-mediated cell death. |
| Q46969634 | Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition |
| Q43019120 | Acetylation of the p53 DNA-binding domain regulates apoptosis induction |
| Q28485141 | Activation of p53 by chemotherapeutic agents enhances reovirus oncolysis |
| Q44329120 | Activation of peroxisome proliferator-activated receptor gamma does not explain the antiproliferative activity of the nonsteroidal anti-inflammatory drug indomethacin on human colorectal cancer cells |
| Q37713569 | Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis |
| Q74314302 | Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax |
| Q35202902 | Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer |
| Q24300313 | Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis |
| Q35567264 | Alterations in the apoptotic machinery and their potential role in anticancer drug resistance |
| Q33589368 | An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort |
| Q39931597 | An intracellular wave of cytochrome c propagates and precedes Bax redistribution during apoptosis |
| Q38933079 | An outline of main factors of drug resistance influencing cancer therapy |
| Q28193724 | An overview of apoptosis and the prevention of colorectal cancer |
| Q38621581 | Analysis of endogenous Bax complexes during apoptosis using blue native PAGE: implications for Bax activation and oligomerization |
| Q34519663 | Androgen and its receptor promote Bax-mediated apoptosis |
| Q49018819 | Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression |
| Q38950137 | Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling. |
| Q33830299 | Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells |
| Q33618830 | Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest |
| Q36704112 | Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway |
| Q28169082 | Antimetastatic activity of a cyclooxygenase-2 inhibitor |
| Q88593255 | Antiproliferative and apoptosis-induction studies of 5-hydroxy 3',4',7-trimethoxyflavone in human breast cancer cells MCF-7: an in vitro and in silico approach |
| Q39816972 | Antiproliferative effect of benzophenones and their influence on cathepsin activity. |
| Q36321735 | Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation. |
| Q43792226 | Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells |
| Q40636941 | Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells |
| Q90265413 | Apoptosis and Autophagy in Picornavirus Infection |
| Q58282847 | Apoptosis and cancer chemotherapy |
| Q77719675 | Apoptosis and cancer: when BAX is TRAILing away |
| Q35915905 | Apoptosis and colorectal cancer |
| Q35764217 | Apoptosis as a novel target for cancer chemoprevention |
| Q35743146 | Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks |
| Q40430535 | Apoptosis in CD30-positive lymphoproliferative disorders of the skin |
| Q35611251 | Apoptosis in human cancer cells |
| Q40305595 | Apoptosis induction by activator protein 2alpha involves transcriptional repression of Bcl-2. |
| Q34676609 | Apoptosis regulation in tetraploid cancer cells |
| Q34395580 | Apoptosis regulators and their role in tumorigenesis |
| Q35552651 | Apoptosis, Chemoresistance, and Breast Cancer: Insights From the MCF-7 Cell Model System |
| Q81077938 | Apoptosis-associated markers and clinical outcome in human oral squamous cell carcinomas |
| Q34742803 | Apoptosis-based therapies |
| Q34520432 | Apoptosis: a link between cancer genetics and chemotherapy |
| Q33983574 | Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway |
| Q39221513 | Apoptotic effect of propyl gallate in activated rat hepatic stellate cells |
| Q34051214 | Apoptotic effects of curcumin on human osteosarcoma U2OS cells. |
| Q37148060 | Apoptotic pathways in tumor progression and therapy |
| Q33828693 | Arsenic-specific stem cell selection during malignant transformation |
| Q37216943 | Artemis is a negative regulator of p53 in response to oxidative stress |
| Q55439392 | Aspirin Prevention of Colorectal Cancer: Focus on NF-κB Signalling and the Nucleolus. |
| Q27851408 | Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. |
| Q28542013 | Aspirin delimits platelet life span by proteasomal inhibition |
| Q39771011 | Aspirin induces apoptosis in human leukemia cells independently of NF-kappaB and MAPKs through alteration of the Mcl-1/Noxa balance |
| Q36645546 | Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model |
| Q28176509 | Aspirin induces apoptosis through release of cytochrome c from mitochondria |
| Q28199915 | Aspirin induces apoptosis through the inhibition of proteasome function |
| Q37425820 | Aspirin, salicylates, and cancer. |
| Q37258255 | Aspirin-induced Bcl-2 translocation and its phosphorylation in the nucleus trigger apoptosis in breast cancer cells |
| Q28579372 | Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release |
| Q39665408 | Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis |
| Q40702714 | BAX and BAK mediate p53-independent suppression of tumorigenesis |
| Q35853029 | BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy |
| Q87342359 | BAX and BCL-2 polymorphisms, as predictors of proliferative vitreoretinopathy development in patients suffering retinal detachment: the Retina 4 project |
| Q35673934 | BAX pro-apoptotic gene alterations in repeated pregnancy loss |
| Q35055572 | BAX supports the mitochondrial network, promoting bioenergetics in nonapoptotic cells |
| Q39073674 | BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells |
| Q27002044 | BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore |
| Q34082489 | BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition? |
| Q50908165 | BCL-2 proteins and apoptosis: Recent insights and unknowns. |
| Q35079498 | BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak |
| Q34581082 | BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs. |
| Q34182014 | BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response |
| Q44663538 | Baicalein induced in vitro apoptosis undergo caspases activity in human promyelocytic leukemia HL-60 cells |
| Q33250477 | Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells |
| Q40301811 | Bax and Bak are the critical complementary effectors of colorectal cancer cell apoptosis by chemopreventive resveratrol |
| Q80484008 | Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa |
| Q79333478 | Bax deficiency affects caspase-2 activation during ultraviolet radiation-induced apoptosis |
| Q39742797 | Bax deficiency mediated drug resistance can be reversed by endoplasmic reticulum stress induced death signaling |
| Q40539983 | Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria. |
| Q60730311 | Bax gene G(-248)A promoter polymorphism is associated with increased lifespan of the neutrophils of patients with osteomyelitis |
| Q39251123 | Bax is essential for death receptor-mediated apoptosis in human colon cancer cells |
| Q36671241 | Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy |
| Q41623743 | Bax is involved in the anticancer activity of Velcade in colorectal cancer |
| Q39947961 | Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release |
| Q43744119 | Bax-dependent apoptosis induced by ceramide in HL-60 cells |
| Q33212700 | Bax-dependent regulation of Bak by voltage-dependent anion channel 2. |
| Q37482805 | Bax/Bak activation in the absence of Bid, Bim, Puma, and p53. |
| Q55070865 | Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis. |
| Q46159185 | Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism |
| Q36298500 | BaxΔ2 is a novel bax isoform unique to microsatellite unstable tumors |
| Q43635757 | BaxΔ2 promotes apoptosis through caspase-8 activation in microsatellite-unstable colon cancer |
| Q39895250 | Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells |
| Q24293601 | Bcl-2 family interaction with the mitochondrial morphogenesis machinery |
| Q37143362 | Bcl-2 family proteins: the sentinels of the mitochondrial apoptosis pathway. |
| Q35947233 | Bcl-2-related genes in lymphoid neoplasia |
| Q41889229 | Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum |
| Q33212894 | Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells |
| Q39963809 | Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells |
| Q40387698 | Bcl-xL/Bax ratio is altered by IFNgamma in TNFalpha- but not in TRAIL-induced apoptosis in colon cancer cell line |
| Q39900645 | Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion |
| Q54604662 | Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms. |
| Q40737329 | Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance |
| Q37500747 | Biomarkers for response to neoadjuvant chemoradiation for rectal cancer |
| Q37684405 | Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. |
| Q39349717 | Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models |
| Q33823655 | Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways. |
| Q36260496 | COX and cancer |
| Q57792141 | CUDC-907 blocks multiple pro-survival signals and abrogates microenvironment protection in CLL |
| Q28478265 | Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway |
| Q39962418 | Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells |
| Q27333877 | Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis |
| Q34011481 | Cancer chemoprevention: a radical perspective |
| Q38812315 | Cancer chemoresistance; biochemical and molecular aspects: a brief overview. |
| Q40351435 | Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. |
| Q42635236 | Cardamonin inhibits colonic neoplasia through modulation of MicroRNA expression |
| Q57082812 | Caspase independence of radio-induced cell death |
| Q40549968 | Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway |
| Q50733554 | Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol. |
| Q38827694 | Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner |
| Q34416282 | Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity |
| Q46972145 | Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation |
| Q27014767 | Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response |
| Q34417153 | Cellular stress response and apoptosis in cancer therapy. |
| Q48365330 | Ceramide increases Fas-mediated apoptosis in glioblastoma cells through FLIP down-regulation |
| Q33183746 | Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells |
| Q39568801 | Chan-Yu-Bao-Yuan-Tang induces apoptosis in NSCLC and SCLC cell lines via a mitochondria-mediated pathway |
| Q36695785 | Characterisation of molecular events following cisplatin treatment of two curable ovarian cancer models: contrasting role for p53 induction and apoptosis in vivo |
| Q37766780 | Chemical biology suggests a role for calcium signaling in mediating sustained JNK activation during apoptosis |
| Q34359198 | Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis |
| Q74107886 | Chemoprevention of colorectal cancer |
| Q28365285 | Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation |
| Q43075231 | Chemopreventive role of etoricoxib (MK-0663) in experimental colon cancer: induction of mitochondrial proapoptotic factors. |
| Q36612788 | Chemoresistance in solid tumours |
| Q53246512 | Chromene induces apoptosis via caspase-3 activation in human leukemia HL-60 cells. |
| Q39964858 | Chromium-mediated apoptosis: involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes |
| Q40543071 | Cigarette smoke condensate-induced transformation of normal human breast epithelial cells in vitro |
| Q40491746 | Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor |
| Q40362003 | Cisplatin and TNF-alpha downregulate transcription of Bcl-xL in murine malignant mesothelioma cells |
| Q36212891 | Clinical potential of inhibitors of survival pathways and activators of apoptotic pathways in treatment of cervical cancer: changing the apoptotic balance. |
| Q61700550 | Clinicopathological correlations of Bcl-xL and Bax expression in differentiated thyroid carcinoma |
| Q37705955 | Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress |
| Q36418980 | Colon cancer and apoptosis. |
| Q34568144 | Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. |
| Q28217992 | Colorectal cancer prevention: is an ounce of prevention worth a pound of cure? |
| Q33387759 | Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax. |
| Q39935218 | Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells |
| Q42474860 | Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation |
| Q33240972 | Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo |
| Q50776703 | Common polymorphism G(-248)A in the promoter region of the bax gene results in significantly shorter survival in patients with chronic lymphocytic Leukemia once treatment is initiated. |
| Q36369402 | Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation. |
| Q39937359 | Continentalic acid from Aralia continentalis induces growth inhibition and apoptosis in HepG2 cells |
| Q35603381 | Control of apoptosis by p53. |
| Q60921028 | Cordycepin induces Bax‑dependent apoptosis in colorectal cancer cells |
| Q35737599 | Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis. |
| Q36580838 | Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model. |
| Q35856974 | Customizing chemotherapy for colon cancer: the potential of gene expression profiling. |
| Q39646598 | Cyclic phosphatidic acid decreases proliferation and survival of colon cancer cells by inhibiting peroxisome proliferator-activated receptor γ. |
| Q39951699 | Cyclin D1 in low-dose radiation-induced adaptive resistance. |
| Q35593965 | Cyclooxygenase inhibition in cancer prevention and treatment |
| Q28193249 | Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention |
| Q35851940 | Cyclooxygenase-2 and gastrointestinal cancer |
| Q28195645 | Cyclooxygenase-2 as a target for anticancer drug development |
| Q35669000 | Cyclooxygenase-2 inhibitors in lung cancer |
| Q28198993 | Cyclooxygenase-independent effects of aspirin on HT-29 human colon cancer cells, revealed by oligonucleotide microarrays |
| Q28213081 | Cyclooxygenases in cancer: progress and perspective |
| Q34077445 | Cytokine-induced tumor suppressors: a GRIM story |
| Q34330920 | Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria |
| Q36118687 | Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA. |
| Q39401750 | Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line |
| Q33254706 | Cytotoxic and apoptotic effects of prenylflavonoid artonin B in human acute lymphoblastic leukemia cells |
| Q90091507 | De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy |
| Q37033587 | Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways |
| Q39987289 | Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of Bax. |
| Q34488147 | Derangement of growth and differentiation control in oncogenesis |
| Q38933258 | Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents. |
| Q50926583 | Destruxins: fungal-derived cyclohexadepsipeptides with multifaceted anticancer and antiangiogenic activities. |
| Q45936657 | Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells. |
| Q36241935 | Development and progression of colorectal neoplasia |
| Q39592538 | Development of small-molecule PUMA inhibitors for mitigating radiation-induced cell death |
| Q33717233 | Development of the human cancer microRNA network |
| Q85855473 | Dichloroacetate affects proliferation but not survival of human colorectal cancer cells |
| Q33918095 | Dichloroacetate induces autophagy in colorectal cancer cells and tumours. |
| Q43762189 | Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells. |
| Q40202994 | Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. |
| Q44926501 | Differential growth inhibition and induction of apoptosis by gossypol between HCT116 and HCT116/Bax(-/-) colorectal cancer cells |
| Q43902939 | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells |
| Q33793136 | Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level |
| Q39675027 | Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway |
| Q38697194 | Dihydroartemisinin and gefitinib synergistically inhibit NSCLC cell growth and promote apoptosis via the Akt/mTOR/STAT3 pathway |
| Q47670493 | Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia. |
| Q30353924 | Direct Activation of Bax Protein for Cancer Therapy |
| Q24307994 | Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis |
| Q92581702 | Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer |
| Q34577387 | Dissecting the dynamic turnover of GFP-LC3 in the autolysosome |
| Q39079636 | Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer |
| Q36594315 | Drug resistance, predictive markers and pharmacogenomics in colorectal cancer |
| Q40698597 | Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma |
| Q28254233 | Drugging the cancer kinome: progress and challenges in developing personalized molecular cancer therapeutics |
| Q40082522 | Dulxanthone A induces cell cycle arrest and apoptosis via up-regulation of p53 through mitochondrial pathway in HepG2 cells |
| Q28189965 | Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis |
| Q64379383 | E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells |
| Q34104165 | ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells |
| Q33271969 | Early apoptosis and cell death induced by ATX-S10Na (II)-mediated photodynamic therapy are Bax- and p53-dependent in human colon cancer cells |
| Q44429648 | Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis |
| Q39028244 | Effect of acetaminophen (paracetamol) on human osteosarcoma cell line MG63. |
| Q40642580 | Effects of a naphthoquinone analog on tumor growth and apoptosis induction |
| Q98386381 | Effects of aspirin on the gastrointestinal tract: Pros vs. cons |
| Q46136538 | Effects of celecoxib and nimesulide on the proliferation of ectopic endometrial stromal cells in vitro |
| Q40485101 | Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60). |
| Q90309167 | Effects of low-dose irradiation on human osteoblasts and periodontal ligament cells |
| Q39854809 | Effects of the anthelmintic drug PF1022A on mammalian tissue and cells |
| Q33410126 | Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade |
| Q26778011 | Eicosanoid pathway in colorectal cancer: Recent updates |
| Q37754720 | Eicosanoids in inflammation and cancer: the role of COX-2. |
| Q33544118 | Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma. |
| Q36907873 | Enhanced 4-hydroxynonenal resistance in KEAP1 silenced human colon cancer cells |
| Q40297433 | Enhanced radiosensitization of p53 mutant cells by oleamide |
| Q40515084 | Enhanced sensitivity of bladder cancer cells to cisplatin mediated cytotoxicity and apoptosis in vitro and in vivo by the selective cyclooxygenase-2 inhibitor JTE-522. |
| Q37694828 | Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles |
| Q35793851 | Epigenetic silencing of BCL6B inactivates p53 signaling and causes human hepatocellular carcinoma cell resist to 5-FU. |
| Q37940106 | Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies |
| Q38907777 | Epithelial-mesenchymal transition contributes to docetaxel resistance in human non-small cell lung cancer |
| Q43769034 | Esophageal cancer prevention in zinc-deficient rats: rapid induction of apoptosis by replenishing zinc |
| Q44446106 | Expression of apoptosis regulators in cutaneous T-cell lymphoma (CTCL) cells. |
| Q28201753 | Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas |
| Q52826936 | Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. |
| Q34735130 | FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells. |
| Q34041856 | Ferroptosis, a new form of cell death relevant to the medical treatment of cancer |
| Q34987859 | Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. |
| Q82677113 | Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis |
| Q54644234 | Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas. |
| Q57699865 | Ganoderic acid Me induces apoptosis through mitochondria dysfunctions in human colon carcinoma cells |
| Q40236988 | Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase |
| Q41858808 | Gene expression profiling reveals two separate mechanisms regulating apoptosis in rectal carcinomas in vivo. |
| Q34813092 | Genetic alterations in ovarian cancer cells that might account for sensitivity to chemotherapy in patients. |
| Q33242983 | Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy |
| Q27007505 | Genotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancer |
| Q51800392 | Growth inhibition and induction of apoptosis in U937 cells by Coptis chinensis extract. |
| Q34154797 | HMGB1 release and redox regulates autophagy and apoptosis in cancer cells |
| Q24596423 | Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression |
| Q35371553 | High cell surface death receptor expression determines type I versus type II signaling |
| Q36396288 | High mobility group protein B1 is an activator of apoptotic response to antimetabolite drugs. |
| Q37542610 | Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer. |
| Q91045685 | Hsp60 and IL-8 axis promotes apoptosis resistance in cancer |
| Q37296982 | Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax. |
| Q34493851 | Human cell knockouts |
| Q40014465 | Human somatic cell gene targeting. |
| Q24301403 | Humanin peptide suppresses apoptosis by interfering with Bax activation |
| Q53880972 | Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells. |
| Q38914905 | Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells |
| Q40048856 | Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells |
| Q52715823 | Hypertonicity-enforced BCL-2 addiction unleashes the cytotoxic potential of death receptors. |
| Q40543909 | Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation |
| Q37520269 | Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy |
| Q37011260 | Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance |
| Q24338320 | Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation |
| Q42959326 | ING1 induces apoptosis through direct effects at the mitochondria. |
| Q39028807 | Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70. |
| Q30999109 | Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach. |
| Q80044869 | Immune restoration in head and neck cancer patients after in vivo COX-2 inhibition |
| Q90677742 | Immunogenic cell death in colon cancer prevention and therapy |
| Q100509884 | Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside |
| Q28483005 | Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells |
| Q46381324 | Importance of Bak for celecoxib-induced apoptosis |
| Q46760469 | In vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3. |
| Q40262487 | In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells. |
| Q40588128 | Induction of androgen receptor-dependent apoptosis in prostate cancer cells by the retinoblastoma protein |
| Q40590740 | Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol |
| Q46617198 | Induction of apoptosis by a stilbene analog involves Bax translocation regulated by p38 MAPK and Akt. |
| Q33195487 | Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner |
| Q44981093 | Induction of apoptosis by yomogin in human promyelocytic leukemic HL-60 cells |
| Q46553586 | Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel |
| Q39481370 | Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by δ-elemene |
| Q24681629 | Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway |
| Q31137239 | Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis |
| Q40013929 | Induction of p21 by p65 in p53 null cells treated with Doxorubicin |
| Q37061407 | Influence of induced reactive oxygen species in p53-mediated cell fate decisions. |
| Q34138113 | Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers |
| Q40205272 | Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells |
| Q40217009 | Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53. |
| Q74717016 | Inhibition of apoptosis in human breast cancer cells: role in tumor progression to the metastatic state |
| Q45153536 | Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites |
| Q40272782 | Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway |
| Q34625596 | Inhibition of tumor angiogenesis by non-steroidal anti-inflammatory drugs: emerging mechanisms and therapeutic perspectives |
| Q35557450 | Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents? |
| Q47367905 | Inhibitory Effect of Aspirin on Cholangiocarcinoma Cells |
| Q46955200 | Inhibitory activity of 6-O-angeloylprenolin from Centipeda minima on farnesyl protein transferase |
| Q60328224 | Innovative DNA-Targeted Metallo-prodrug Strategy Combining Histone Deacetylase Inhibition with Oxidative Stress |
| Q24645231 | Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis |
| Q39569412 | Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia |
| Q34576589 | Integrity of p53 associated pathways determines induction of apoptosis of tumor cells resistant to Aurora-A kinase inhibitors |
| Q28480559 | Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis |
| Q39858333 | Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells. |
| Q40455509 | Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175. |
| Q39361670 | Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes. |
| Q44673360 | Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog |
| Q28576777 | Involvement of mitochondrial- and Fas-mediated dual mechanism in CoCl2-induced apoptosis of rat PC12 cells |
| Q40157555 | Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis |
| Q38300322 | Irinotecan activates p53 with its active metabolite, resulting in human hepatocellular carcinoma apoptosis |
| Q35547957 | Is Bax/Bcl-2 ratio considered as a prognostic marker with age and tumor location in colorectal cancer? |
| Q33894543 | Ku86 is essential in human somatic cells |
| Q45295631 | Laquinimod decreases Bax expression and reduces caspase-6 activation in neurons |
| Q34221234 | Lessons from anticancer research might provide new insights into mechanisms of hormone action |
| Q35916071 | Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability |
| Q92791139 | Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5-fluorouracil in vivo |
| Q38903188 | Longikaurin E induces apoptosis of pancreatic cancer cells via modulation of the p38 and PI3K/AKT pathways by ROS. |
| Q24534937 | Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis |
| Q35774126 | Loss of soluble N-ethylmaleimide-sensitive factor attachment protein α (αSNAP) induces epithelial cell apoptosis via down-regulation of Bcl-2 expression and disruption of the Golgi |
| Q37505528 | Loss of the proteins Bak and Bax prevents apoptosis mediated by histone deacetylase inhibitors. |
| Q51981021 | Low BAX protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma. |
| Q40794489 | Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity |
| Q47895480 | Lymphoma development in Bax transgenic mice is inhibited by Bcl-2 and associated with chromosomal instability. |
| Q24337383 | MAP-1 is a mitochondrial effector of Bax. |
| Q46599463 | Marine steroid derived from Acropora formosa enhances mitochondrial-mediated apoptosis in non-small cell lung cancer cells |
| Q61818162 | Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells |
| Q33306334 | Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis |
| Q47624759 | Measurement of BH3-only protein tolerance. |
| Q36524971 | Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation. |
| Q26738528 | Mechanisms of drug resistance in colon cancer and its therapeutic strategies |
| Q28199646 | Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer |
| Q46747952 | Meloxicam inhibits osteosarcoma growth, invasiveness and metastasis by COX-2-dependent and independent routes |
| Q39965538 | Methyl jasmonate induces cell death with mixed characteristics of apoptosis and necrosis in cervical cancer cells |
| Q34158848 | Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells |
| Q45167295 | Methylation-induced silencing of ASC and the effect of expressed ASC on p53-mediated chemosensitivity in colorectal cancer |
| Q46592737 | Methyltransferase inhibition induces p53-dependent apoptosis and a novel form of cell death |
| Q39064483 | MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX. |
| Q54408048 | MicroRNA-128 downregulates Bax and induces apoptosis in human embryonic kidney cells. |
| Q91499928 | MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1 |
| Q34781340 | Microsatellite instability and prostate cancer: clinical and pathological implications |
| Q37535535 | Mitochondria and energetic depression in cell pathophysiology |
| Q40722888 | Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors |
| Q35137160 | Mitochondria as a target for inducing death of malignant hematopoietic cells. |
| Q36245552 | Mitochondria: A novel target for the chemoprevention of cancer |
| Q30167710 | Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. |
| Q40212962 | Mitochondrial control of cell death induced by hyperosmotic stress |
| Q35025248 | Mitochondrial energy dissipation by fatty acids. Mechanisms and implications for cell death |
| Q59647253 | Mitochondrial permeability transition induced by novel pyridothiopyranopyrimidine derivatives: Potential new antimitochondrial antitumour agents |
| Q37700096 | Mitochondrial signaling in cell death via the Bcl-2 family |
| Q40697059 | Mitochondrial targeting drug lonidamine triggered apoptosis in doxorubicin-resistant HepG2 cells. |
| Q42770281 | Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX. |
| Q28536697 | Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data |
| Q45251349 | Modulation of mitochondrial transition pore components by thyroid hormone |
| Q36963807 | Molecular markers in colorectal cancer: genetic bases for a customised treatment. |
| Q38799295 | Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells. |
| Q37719938 | Molecular mechanisms of chemoresistance in osteosarcoma (Review). |
| Q34382998 | Molecular mechanisms of drug resistance |
| Q33547038 | Morphological and biochemical changes during formocresol induced cell death in murine peritoneal macrophages: apoptotic and necrotic features |
| Q33207662 | Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway |
| Q34493866 | Multiple roles of the tumor suppressor p53. |
| Q43114556 | Murine erythropoietic impairment induced by paclitaxel: interactions of GATA-1 and erythroid Krüppel-like transcription factors, apoptotic related proteins and erythropoietin receptor |
| Q34338754 | Muscarinic receptor activation protects cells from apoptotic effects of DNA damage, oxidative stress, and mitochondrial inhibition |
| Q43105405 | Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation |
| Q39288182 | NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria. |
| Q39160218 | NK4 regulates 5-fluorouracil sensitivity in cholangiocarcinoma cells by modulating the intrinsic apoptosis pathway |
| Q92092747 | NOXA-dependent contextual synthetic lethality of BCL-XL inhibition and "osmotic reprogramming" in colorectal cancer |
| Q34270948 | NOXA-induced alterations in the Bax/Smac axis enhance sensitivity of ovarian cancer cells to cisplatin |
| Q24319576 | NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling |
| Q42444746 | NSAIDs downregulate Bcl-X(L) and dissociate BAX and Bcl-X(L) to induce apoptosis in colon cancer cells |
| Q36173491 | NSAIDs in neuroblastoma therapy. |
| Q43726776 | NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. |
| Q42775840 | National Cancer Institute workshop on chemopreventive properties of nonsteroidal anti-inflammatory drugs: role of COX-dependent and -independent mechanisms |
| Q37924114 | Natural salicylates: foods, functions and disease prevention |
| Q36647000 | Neem oil limonoids induces p53-independent apoptosis and autophagy. |
| Q35021171 | New avenues for the prevention of colorectal cancer: targeting cyclo-oxygenase-2 activity |
| Q34098881 | Nicotinamide inhibits alkylating agent-induced apoptotic neurodegeneration in the developing rat brain |
| Q28166312 | Non steroidal anti-inflammatory drugs and COX-2 inhibitors as anti-cancer therapeutics: hypes, hopes and reality |
| Q36582948 | Non-steroidal anti-inflammatory drugs to potentiate chemotherapy effects: from lab to clinic |
| Q35150716 | Nonredundant role of Bax and Bak in Bid-mediated apoptosis |
| Q28195436 | Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy |
| Q64377174 | Nonsteroidal anti-inflammatory drugs induce colorectal cancer cell apoptosis by suppressing 14-3-3epsilon |
| Q46446922 | Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by perturbing peroxisome proliferator-activated receptor-delta transcriptional pathway |
| Q40176341 | Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway. |
| Q35640090 | Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction |
| Q36133255 | Novel therapeutics in colorectal cancer |
| Q43833445 | Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia |
| Q24310705 | Noxa in colorectal cancer: a study on DNA, mRNA and protein expression |
| Q38360989 | Nuclear factor-kappaB, induced in human carcinoma cell line A2780 by the new anthracycline men 10755, is devoid of transcriptional activity |
| Q39067763 | Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin |
| Q38915116 | Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line |
| Q37263062 | Oncogenic transformation confers a selective susceptibility to the combined suppression of the proteasome and autophagy |
| Q42207479 | Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis |
| Q92765361 | Overcoming drug-resistance in lung cancer cells by paclitaxel loaded galactoxyloglucan nanoparticles |
| Q35136082 | Overcoming resistance of cancer cells to apoptosis |
| Q37148067 | Overcoming resistance to apoptosis in cancer therapy |
| Q40408250 | Overexpression of Bax induces apoptosis and enhances drug sensitivity of hepatocellular cancer-9204 cells |
| Q73693790 | Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice |
| Q59798268 | Overexpression of microRNA-183 promotes apoptosis of substantia nigra neurons via the inhibition of OSMR in a mouse model of Parkinson's disease |
| Q40521489 | Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA. |
| Q40284724 | Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint. |
| Q104758287 | Oxidative stress-mediated induction of pulmonary oncogenes, inflammatory, and apoptotic markers following time-course exposure to ethylene glycol monomethyl ether in rats |
| Q38295612 | PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells |
| Q33767159 | PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation |
| Q42944759 | PUMA Kills Stem Cells to Stall Cancer? |
| Q24291462 | PUMA induces the rapid apoptosis of colorectal cancer cells |
| Q24550772 | PUMA mediates the apoptotic response to p53 in colorectal cancer cells |
| Q40620684 | PUMA suppresses intestinal tumorigenesis in mice |
| Q40378335 | Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS). |
| Q89286292 | Patrinia scabiosaefolia Inhibits Growth of 5-FU-Resistant Colorectal Carcinoma Cells via Induction of Apoptosis and Suppression of AKT Pathway |
| Q42664663 | Peptides derived from the transmembrane domain of Bcl-2 proteins as potential mitochondrial priming tools |
| Q46566643 | Peroxisome proliferator-activated receptor delta as a molecular target to regulate lung cancer cell growth |
| Q44687763 | Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription |
| Q37391765 | Pharmacologic effects of NSAIDs and implications for the risks and benefits of long-term prophylactic use of aspirin to prevent cancer. |
| Q46735228 | Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells |
| Q54341133 | Phenylarsine oxide induces apoptosis in Bax- and Bak-deficient cells through upregulation of Bim. |
| Q24295177 | Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase |
| Q40595732 | Phosphorylation status of c-Kit and Epo receptors, and the presence of wild-type p53 confer in vitro resistance of murine erythroleukemic cells to Celecoxib |
| Q50955417 | Photodynamic therapy-induced death of HCT 116 cells: Apoptosis with or without Bax expression. |
| Q38980630 | Photosensitizing mechanism and identification of levofloxacin photoproducts at ambient UV radiation. |
| Q35648476 | Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells. |
| Q41676295 | Picornaviruses and Apoptosis: Subversion of Cell Death |
| Q38702112 | Piperine attenuates UV-R induced cell damage in human keratinocytes via NF-kB, Bax/Bcl-2 pathway: An application for photoprotection |
| Q53273558 | Piroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathway. |
| Q43610216 | Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer |
| Q41549687 | Potential impact of (rs 4645878) BAX promoter -248G>A and (rs 1042522) TP53 72Arg>pro polymorphisms on epithelial ovarian cancer patients |
| Q39188578 | Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. |
| Q35748569 | Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak. |
| Q28210996 | Prevention of colorectal cancer through the use of COX-2 selective inhibitors |
| Q53339813 | Primary colorectal tumors fail to express the proapoptotic mediator PTAG and its reexpression augments drug-induced apoptosis. |
| Q100302901 | Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90 |
| Q53652463 | Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK. |
| Q92157192 | Proapoptotic Index Evaluation of Two Synthetic Peptides Derived from the Coneshell Californiconus californicus in Lung Cancer Cell Line H1299 |
| Q34447950 | Prolactin, a lymphocyte growth and survival factor |
| Q28510195 | Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation |
| Q28188827 | Prostaglandins and cancer |
| Q40604705 | Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells |
| Q39550544 | Protective effects of glycyrrhizin against β₂-adrenergic receptor agonist-induced receptor internalization and cell apoptosis |
| Q28553350 | Protein Kinase RNA-Like Endoplasmic Reticulum Kinase-Mediated Bcl-2 Protein Phosphorylation Contributes to Evodiamine-Induced Apoptosis of Human Renal Cell Carcinoma Cells |
| Q42800738 | Protein kinase inhibitor 2-aminopurine overrides multiple genotoxic stress-induced cellular pathways to promote cell survival |
| Q33963772 | Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1 |
| Q45970615 | Quercetin can act either as an inhibitor or an inducer of the mitochondrial permeability transition pore: A demonstration of the ambivalent redox character of polyphenols. |
| Q101121399 | RTKN2 is Associated with Unfavorable Prognosis and Promotes Progression in Non-Small-Cell Lung Cancer |
| Q35878431 | Rapamycin rescues ABT-737 efficacy in small cell lung cancer |
| Q92034324 | Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis |
| Q36279284 | Rational development of a cytotoxic peptide to trigger cell death |
| Q28541488 | Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies |
| Q40110911 | Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. |
| Q37901739 | Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). |
| Q44353683 | Regulation of 17-AAG-induced apoptosis: role of Bcl-2, Bcl-XL, and Bax downstream of 17-AAG-mediated down-regulation of Akt, Raf-1, and Src kinases |
| Q40533674 | Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways |
| Q44028246 | Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells |
| Q37213830 | Regulation of mammalian target of rapamycin complex 1 by Bcl-2 and Bcl-XL proteins |
| Q40609042 | Regulation of p53 stability and function in HCT116 colon cancer cells |
| Q40366301 | Release of cytochrome c from isolated mitochondria by etoposide |
| Q39685758 | Requirement of BAX for efficient adenovirus-induced apoptosis |
| Q46923218 | Resistance of cancers to immunologic cytotoxicity and adoptive immunotherapy via X-linked inhibitor of apoptosis protein expression and coexisting defects in mitochondrial death signaling |
| Q43938032 | Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status |
| Q35309349 | Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation. |
| Q40447515 | Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. |
| Q34222357 | Retracted: Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis |
| Q36041152 | Review article: the potential of combinational regimen with non-steroidal anti-inflammatory drugs in the chemoprevention of colorectal cancer |
| Q42726169 | Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells |
| Q90484826 | Role and regulation of proapoptotic Bax in oral squamous cell carcinoma and drug resistance |
| Q24806345 | Role of APC and DNA mismatch repair genes in the development of colorectal cancers |
| Q89841927 | Role of Apelin/APJ axis in cancer development and progression |
| Q40787492 | Role of Bax in apoptosis of IL-3-dependent cells. |
| Q24793084 | Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells |
| Q34733047 | Role of Bcl-2 family of proteins in malignancy |
| Q37331465 | Role of apoptosis in colon cancer biology, therapy, and prevention |
| Q36070436 | Role of inflammation in mouse lung tumorigenesis: a review |
| Q21245590 | Role of insulin-like growth factor binding protein-4 in prevention of colon cancer |
| Q37210853 | Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death |
| Q39580347 | Role of nonsteroidal anti-inflammatory drug-activated gene-1 in docetaxel-induced cell death of human colorectal cancer cells with different p53 status |
| Q87153648 | Role of p53, Bax, p21, and DNA-PKcs in radiation sensitivity of HCT-116 cells and xenografts |
| Q44399860 | Role of polymorphisms in BCL-2 and BAX genes in modulating the risk of developing non-Hodgkin lymphoma |
| Q40440440 | SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma |
| Q36938061 | SDX-308 and SDX-101, non-steroidal anti-inflammatory drugs, as therapeutic candidates for treating hematologic malignancies including myeloma |
| Q46825444 | SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release |
| Q28284206 | SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events |
| Q37695388 | SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells |
| Q87292212 | STAT5A is regulated by DNA damage via the tumor suppressor p53 |
| Q53537067 | Saucernetin-7 isolated from Saururus chinensis induces caspase-dependent apoptosis in human promyelocytic leukemia HL-60 cells. |
| Q40044277 | Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids |
| Q31142615 | Screening for novel protein targets of indomethacin in HCT116 human colon cancer cells using proteomics |
| Q40336893 | Sensitization of DNA damage-induced apoptosis by the proteasome inhibitor PS-341 is p53 dependent and involves target proteins 14-3-3sigma and survivin |
| Q41135486 | Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis |
| Q34227735 | Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis |
| Q39960515 | Severe acute respiratory syndrome coronavirus 3a protein activates the mitochondrial death pathway through p38 MAP kinase activation. |
| Q37265616 | Significance of Bcl-xL in human colon carcinoma |
| Q92702103 | Silica Nanoparticles Provoke Cell Death Independent of p53 and BAX in Human Colon Cancer Cells |
| Q48548442 | Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo |
| Q33200961 | Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells |
| Q46876071 | Sorbitol-induced apoptosis of human leukemia is mediated by caspase activation and cytochrome c release |
| Q43971307 | Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells. |
| Q36422392 | Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis |
| Q44362013 | Stem cell factor protects erythroid precursor cells from chemotherapeutic agents via up-regulation of BCL-2 family proteins |
| Q36113165 | Stress-induced p53 runs a transcription-independent death program |
| Q50853629 | Structural Determinants of p53-Independence in Anticancer Ruthenium-Arene Schiff-Base Complexes. |
| Q50932128 | Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations. |
| Q36610436 | Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAX. |
| Q40149688 | Sulindac Sulfide Differentially Induces Apoptosis in Smac-Proficient and -Deficient Human Colon Cancer Cells |
| Q40055810 | Sulindac and its metabolites induce carcinogen metabolizing enzymes in human colon cancer cells. |
| Q83940372 | Sulindac and its metabolites: sulindac sulfide and sulindac sulfone enhance cytotoxic effects of arsenic trioxide on leukemic cell lines |
| Q46453863 | Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice |
| Q46951961 | Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells |
| Q40361538 | Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2. |
| Q34578697 | Sulindac treatment in hereditary non-polyposis colorectal cancer |
| Q27682952 | Sulindac-Derived RXRα Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site |
| Q40202711 | Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction |
| Q64378845 | Suppressing the growth of rectal cancer xenografts derived from patient tumors by an adenovector expressing small hairpin RNA targeting Bcl-XL |
| Q96818364 | Suppression of Cisplatin-Induced Hepatic Injury in Rats Through Alarmin High-Mobility Group Box-1 Pathway by Ganoderma lucidum: Theoretical and Experimental Study |
| Q40688646 | Synergistic cytotoxicity and apoptosis of JTE-522, a selective cyclooxygenase-2 inhibitor, and 5-fluorouracil against bladder cancer |
| Q44389071 | Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway |
| Q37082125 | Synthesis and SAR study of modulators inhibiting tRXRα-dependent AKT activation. |
| Q53151027 | Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols. |
| Q47601521 | Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway |
| Q40436643 | TNF-alpha promotes Doxorubicin-induced cell apoptosis and anti-cancer effect through downregulation of p21 in p53-deficient tumor cells |
| Q39239250 | TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis |
| Q33213562 | TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway |
| Q39753656 | TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. |
| Q40165924 | TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. |
| Q43244354 | Tanshinone II A induces apoptosis and S phase cell cycle arrest in activated rat hepatic stellate cells |
| Q34554287 | Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells |
| Q33441616 | Targeted quantitative mass spectrometric identification of differentially expressed proteins between Bax-expressing and deficient colorectal carcinoma cells. |
| Q39064624 | Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A. |
| Q34736820 | Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode |
| Q91136717 | Targeting BAX ubiquitin-binding sites reveals that BAX activation is essential for its ubiquitin-dependent degradation |
| Q39197893 | Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation. |
| Q34568964 | Targeting apoptosis in cancer chemotherapy |
| Q42116107 | Targeting colorectal cancer stem cells with inducible caspase-9 |
| Q36475129 | Targeting cyclooxygenase-2 for prevention and therapy of colorectal cancer |
| Q34791120 | Targeting death and decoy receptors of the tumour-necrosis factor superfamily |
| Q90720782 | Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models |
| Q38034442 | Targeting proteomics to investigate metastasis-associated mitochondrial proteins |
| Q80456226 | The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds |
| Q35591695 | The Bcl-2 family: roles in cell survival and oncogenesis. |
| Q29614982 | The Bcl2 family: regulators of the cellular life-or-death switch |
| Q44650578 | The Chemopreventive Agent Sulindac Attenuates Expression of the Antiapoptotic Protein Survivin in Colorectal Carcinoma Cells |
| Q28397675 | The Effect of Growth Hormone Administration on the Regulation of Mitochondrial Apoptosis in-Vivo |
| Q57175391 | The Effects of Potassium Cyanide on the Functional Recovery of Isolated Rat Hearts after Ischemia and Reperfusion: The Role of Oxidative Stress |
| Q36029051 | The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis |
| Q90325999 | The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects |
| Q38621569 | The N-terminal conformation of Bax regulates cell commitment to apoptosis |
| Q42157330 | The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage |
| Q38836645 | The anticancer mechanism of 2'-hydroxycinnamaldehyde in human head and neck cancer cells |
| Q33717586 | The apoptotic response in HCT116 BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein |
| Q40116894 | The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells |
| Q79281281 | The cyclooxygenase-2 pathway as a target for treatment or prevention of cancer |
| Q34837015 | The emergence of resistance to targeted cancer therapeutics |
| Q36542788 | The impact of post-transcriptional regulation in the p53 network |
| Q43967962 | The mitochondrial apoptosis-inducing factor plays a role in E2F-1-induced apoptosis in human colon cancer cells |
| Q92863039 | The molecular targets of diclofenac differs from ibuprofen to induce apoptosis and epithelial mesenchymal transition due to alternation on oxidative stress management p53 independently in PC3 prostate cancer cells |
| Q81726502 | The murine cytomegalovirus cell death suppressor m38.5 binds Bax and blocks Bax-mediated mitochondrial outer membrane permeabilization |
| Q53035836 | The oncolytic compound LTX-401 targets the Golgi apparatus. |
| Q43854589 | The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells |
| Q35680535 | The role of Bcl-2 family members in tumorigenesis |
| Q37566195 | The role of HRK gene in human cancer |
| Q28192066 | The role of eicosanoids, cyclooxygenases, and nonsteroidal anti-inflammatory drugs in colorectal tumorigenesis and chemoprevention |
| Q42239401 | The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma. |
| Q36123763 | The role of prostaglandins and other eicosanoids in the gastrointestinal tract |
| Q36302070 | The signaling and apoptotic effects of TNF-related apoptosis-inducing ligand in HIV-1 associated dementia |
| Q51092684 | The substitution of Proline 168 favors Bax oligomerization and stimulates its interaction with LUVs and mitochondria. |
| Q28248026 | The transcriptional targets of p53 in apoptosis control |
| Q37313219 | Therapeutic modulation of apoptosis: targeting the BCL-2 family at the interface of the mitochondrial membrane |
| Q38696056 | Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. |
| Q38130924 | Thyroid hormone, thyromimetics, and metabolic efficiency |
| Q41966800 | Tissue transglutaminase serves as an inhibitor of apoptosis by cross-linking caspase 3 in thapsigargin-treated cells |
| Q28482454 | Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression |
| Q34786705 | Topoisomerase I requirement for death receptor-induced apoptotic nuclear fission |
| Q37148071 | Trail receptors: targets for cancer therapy |
| Q34802156 | Transcriptional role of p53 in interferon-mediated antiviral immunity. |
| Q40419653 | Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptosis via Bax activation |
| Q35317287 | Transformations of the macromolecular landscape at mitochondria during DNA-damage-induced apoptotic cell death. |
| Q36213081 | Tumor suppression by resistant maltodextrin, Fibersol-2. |
| Q40752768 | Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. |
| Q43903493 | Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. |
| Q24304043 | UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation |
| Q40274243 | Upregulation of BAK by butyrate in the colon is associated with increased Sp3 binding. |
| Q39868796 | Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death |
| Q43727975 | Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells |
| Q33914559 | Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins |
| Q35160453 | Vinblastine-induced apoptosis is mediated by discrete alterations in subcellular location, oligomeric structure, and activation status of specific Bcl-2 family members |
| Q84702792 | WITHDRAWN: Reprint of: Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins |
| Q39430569 | Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression |
| Q40204086 | Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway |
| Q40366406 | Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression |
| Q80308829 | [Cyclooxygenase 2 and colorectal cancer: therapeutic implications] |
| Q37460431 | beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium |
| Q46966391 | c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells |
| Q40291410 | hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway. |
| Q36156993 | mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation. |
| Q36950630 | miR-139-5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2 |
| Q59910671 | p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways |
| Q33905382 | p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels |
| Q24657909 | p53 acetylation is crucial for its transcription-independent proapoptotic functions |
| Q42576880 | p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells |
| Q63408383 | p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation |
| Q34397020 | p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 |
| Q36163707 | p53: twenty five years understanding the mechanism of genome protection |