| Q39366387 | A Bax-mediated mechanism for obatoclax-induced apoptosis of cholangiocarcinoma cells |
| Q35740210 | A New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells. |
| Q37209072 | A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy |
| Q44133736 | A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile |
| Q40394969 | Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line |
| Q40709009 | Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin. |
| Q33295311 | Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak. |
| Q35601550 | Altered mitochondrial apoptotic pathway in placentas from undernourished rat gestations |
| Q36074708 | Apoptosis-inducing factor (AIF) is targeted in IFN-α2a-induced Bid-mediated apoptosis through Bak activation in ovarian cancer cells |
| Q36036927 | Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells |
| Q21261236 | BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells |
| Q36424182 | Bak is a key molecule in apoptosis induced by methanol extracts of Codonopsis lanceolata and Tricholoma matsutake in HSC-2 human oral cancer cells |
| Q33212700 | Bax-dependent regulation of Bak by voltage-dependent anion channel 2. |
| Q42667002 | Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation |
| Q41889229 | Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum |
| Q39674453 | Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis |
| Q29616694 | Cancer drug resistance: an evolving paradigm |
| Q36735381 | Celecoxib Enhances the Chemotherapeutic Response of Cisplatin and TNF-α in SiHa Cells through Reactive Oxygen Species-Mediated Mitochondrial Pathway |
| Q35605849 | Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101) |
| Q30413236 | Cisplatin inhibits hippocampal cell proliferation and alters the expression of apoptotic genes |
| Q39829234 | Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation. |
| Q28215534 | Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition |
| Q35165025 | Death pathways activated in CaCo-2 cells by Clostridium perfringens enterotoxin |
| Q40663033 | Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion |
| Q43902939 | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells |
| Q35880102 | Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation |
| Q44198666 | Early mitochondrial activation and cytochrome c up-regulation during apoptosis |
| Q44117859 | Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines. |
| Q91588254 | Genetic Aberrations Associated with Photodynamic Therapy in Colorectal Cancer Cells |
| Q44863828 | Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death |
| Q38367375 | How do viruses control mitochondria-mediated apoptosis? |
| Q24306784 | Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis |
| Q44620594 | Induction of apoptosis without redox catastrophe by thioredoxin-inhibitory compounds |
| Q42254718 | Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells |
| Q40066545 | Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin |
| Q44526170 | Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax. |
| Q35747444 | Key role for Bak activation and Bak-Bax interaction in the apoptotic response to vinblastine |
| Q40561579 | LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways |
| Q24337383 | MAP-1 is a mitochondrial effector of Bax. |
| Q35954258 | Mechanisms of resistance to TRAIL-induced apoptosis in cancer |
| Q27026521 | Mitochondrial glutathione: features, regulation and role in disease |
| Q73555967 | Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells |
| Q37180866 | Molecular regulation of DNA damage-induced apoptosis in neurons of cerebral cortex |
| Q35107469 | Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA. |
| Q47886250 | Mutations of the BAK gene are infrequent in advanced gastric adenocarcinomas in Koreans |
| Q39627618 | Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis |
| Q30361951 | Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells. |
| Q44028246 | Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells |
| Q36376406 | Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells |
| Q46988935 | Rosmarinic acid failed to suppress hydrogen peroxide-mediated apoptosis but induced apoptosis of Jurkat cells which was suppressed by Bcl-2. |
| Q43984324 | Sequence and functional similarities between pro-apoptotic Bid and plant lipid transfer proteins |
| Q38960298 | Suppression of PI3K/Akt signaling by synthetic bichalcone analog TSWU-CD4 induces ER stress- and Bax/Bak-mediated apoptosis of cancer cells |
| Q38034442 | Targeting proteomics to investigate metastasis-associated mitochondrial proteins |
| Q28397675 | The Effect of Growth Hormone Administration on the Regulation of Mitochondrial Apoptosis in-Vivo |
| Q35541834 | The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak |
| Q24317331 | The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression |
| Q40306488 | Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1. |