| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Stanley J. Korsmeyer | Q138795 |
| P2093 | author name string | Saito M | |
| Oh KJ | |||
| Weiler S | |||
| Schlesinger PH | |||
| Wei MC | |||
| P2860 | cites work | An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 | Q22009407 |
| Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC | Q22009974 | ||
| Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria | Q22011013 | ||
| Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c | Q24309066 | ||
| Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors | Q24310559 | ||
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis | Q24310597 | ||
| Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade | Q24311006 | ||
| Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death | Q24312211 | ||
| Inhibition of Bax channel-forming activity by Bcl-2 | Q24317099 | ||
| BID: a novel BH3 domain-only death agonist | Q24320091 | ||
| Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 | Q24324482 | ||
| Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis | Q24533270 | ||
| Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis | Q24669892 | ||
| Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis | Q24670370 | ||
| Movement of Bax from the cytosol to mitochondria during apoptosis | Q24677881 | ||
| Solution structure of BID, an intracellular amplifier of apoptotic signaling | Q27617719 | ||
| Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists | Q27617723 | ||
| X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death | Q27733156 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
| The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9 | Q28272159 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death | Q28586301 | ||
| Caspases: enemies within | Q29547315 | ||
| Mitochondria and apoptosis | Q29547905 | ||
| BCL-2 family members and the mitochondria in apoptosis | Q29614427 | ||
| The Bcl-2 protein family: arbiters of cell survival | Q29618158 | ||
| Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death | Q29620000 | ||
| BAX-dependent transport of cytochrome c reconstituted in pure liposomes | Q33912996 | ||
| Signal transduction by allosteric receptor oligomerization | Q34165171 | ||
| Regulated targeting of BAX to mitochondria. | Q36255507 | ||
| The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol | Q36301514 | ||
| Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations | Q36353924 | ||
| Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. | Q36593741 | ||
| Lethal effect of the anti-Fas antibody in mice | Q36696599 | ||
| BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases | Q37044625 | ||
| Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis | Q38326924 | ||
| Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. | Q40980272 | ||
| Ion channel activity of the BH3 only Bcl-2 family member, BID. | Q41681453 | ||
| Pharmacological modifications of the sodium channels of frog nerve | Q42954159 | ||
| Bcl-2 family proteins | Q46508339 | ||
| Bcl-2-family proteins: the role of the BH3 domain in apoptosis | Q47686942 | ||
| Bcl-x(L) forms an ion channel in synthetic lipid membranes. | Q54571984 | ||
| Nonionic detergents induce dimerization among members of the Bcl-2 family | Q73343305 | ||
| The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition | Q74358996 | ||
| Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange | Q74607067 | ||
| Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A | Q77406620 | ||
| P433 | issue | 12 | |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 1166-1173 | |
| P577 | publication date | 2000-12-01 | |
| P1433 | published in | Cell Death & Differentiation | Q2943974 |
| P1476 | title | Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. | |
| P478 | volume | 7 |
| Q34311770 | A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway |
| Q38970508 | A Mitocentric View of Alzheimer's Disease |
| Q37689440 | A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage. |
| Q58595359 | A mini review of fluoride-induced apoptotic pathways |
| Q53719634 | A multimeric model for murine anti-apoptotic protein Bcl-2 and structural insights for its regulation by post-translational modification |
| Q44373972 | A new anticancer compound, oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through Bax activation |
| Q58762210 | A novel prognostic marker and immunogenic membrane antigen: prohibitin (PHB) in pancreatic cancer |
| Q34241381 | A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo |
| Q40793451 | A role for mitochondrial Bak in apoptotic response to anticancer drugs |
| Q36250860 | A systematic review on ethnomedicines of anti-cancer plants. |
| Q35996719 | ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines |
| Q40010724 | ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity |
| Q47796655 | Actin dependent CD95 internalization is specific for Type I cells |
| Q44156173 | Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. |
| Q40644298 | Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria |
| Q39455810 | Activation of apoptotic signalling events in human embryonic stem cells upon Coxsackievirus B3 infection |
| Q34384160 | Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis |
| Q48174791 | Activation of the extrinsic caspase pathway in cultured cortical neurons requires p53-mediated down-regulation of the X-linked inhibitor of apoptosis protein to induce apoptosis. |
| Q53605400 | Acyl coenzyme A-binding protein augments bid-induced mitochondrial damage and cell death by activating mu-calpain. |
| Q44493800 | Adenoviral melanoma differentiation-associated gene 7 induces apoptosis in lung cancer cells through mitochondrial permeability transition-independent cytochrome c release |
| Q53424475 | Allostery in BAX protein activation. |
| Q50077375 | An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis |
| Q40161643 | Analysis of CD95 threshold signaling: triggering of CD95 (FAS/APO-1) at low concentrations primarily results in survival signaling |
| Q46832846 | Analysis of apoptosis induced by perfluorooctane sulfonates (PFOS) in mouse Leydig cells in vitro |
| Q34648801 | And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis |
| Q39882887 | Antiangiogenic and proapoptotic activities of allyl isothiocyanate inhibit ascites tumor growth in vivo. |
| Q73288772 | Antiapoptotic effect of EGF on mouse hepatocytes associated with downregulation of proapoptotic Bid protein |
| Q37504822 | Anticancer activity of a monobenzyltin complex C1 against MDA-MB-231 cells through induction of Apoptosis and inhibition of breast cancer stem cells |
| Q35603092 | Anticancer therapy targeting the apoptotic pathway |
| Q36382247 | Apoptosis and necrosis in the liver: a tale of two deaths? |
| Q36300771 | Apoptosis of AGS human gastric adenocarcinoma cells by methanolic extract of Dictamnus |
| Q33810050 | Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling |
| Q35546843 | Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury |
| Q92237924 | Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines |
| Q42089456 | Arrestins in apoptosis |
| Q40323169 | Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent |
| Q37151053 | Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis |
| Q35783731 | Association of a Methanol Extract of Rheum undulatum L. Mediated Cell Death in AGS Cells with an Intrinsic Apoptotic Pathway |
| Q54414564 | Association of overexpression of hexokinase II with chemoresistance in epithelial ovarian cancer. |
| Q47117386 | Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak. |
| Q34249024 | B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins |
| Q36388507 | B7-H1 limits the entry of effector CD8(+) T cells to the memory pool by upregulating Bim |
| Q24295530 | BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove |
| Q40702714 | BAX and BAK mediate p53-independent suppression of tumorigenesis |
| Q42431105 | BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation |
| Q42598140 | BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization |
| Q36419013 | BCL2 family of apoptosis-related genes: functions and clinical implications in cancer |
| Q28468367 | BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer |
| Q34168014 | BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells |
| Q52878050 | BH3-only proteins: possible proapoptotic triggers for melanoma therapy. |
| Q34182014 | BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response |
| Q40092563 | BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma. |
| Q35955377 | Baicalein Induces Caspase-dependent Apoptosis Associated with the Generation of ROS and the Activation of AMPK in Human Lung Carcinoma A549 Cells |
| Q41914649 | Bak and Bax are non-redundant during infection- and DNA damage-induced apoptosis |
| Q43156404 | Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains |
| Q47139100 | Bardoxolone methyl (CDDO-Me or RTA402) induces cell cycle arrest, apoptosis and autophagy via PI3K/Akt/mTOR and p38 MAPK/Erk1/2 signaling pathways in K562 cells |
| Q45119715 | Bax affects intracellular Ca2+ stores and induces Ca2+ wave propagation |
| Q28507634 | Bax and Bak independently promote cytochrome C release from mitochondria |
| Q79434810 | Bax and the mitochondrial permeability transition cooperate in the release of cytochrome c during endoplasmic reticulum-stress-induced apoptosis |
| Q34361458 | Bax expression measured by AQUAnalysis is an independent prognostic marker in oral squamous cell carcinoma |
| Q40170925 | Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway |
| Q36018810 | Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species |
| Q43002476 | Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. |
| Q46715796 | Bax siRNA promotes survival of cultured and allografted granule cell precursors through blockade of caspase-3 cleavage. |
| Q34486441 | Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function |
| Q35596565 | Bax translocation and mitochondrial fragmentation induced by Helicobacter pylori |
| Q80199717 | Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection |
| Q36746422 | Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells |
| Q35928205 | Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival |
| Q37310180 | Bcl-2 family proteins and cancer |
| Q37465922 | Bcl-2 proteins bid and bax form a network to permeabilize the mitochondria at the onset of apoptosis. |
| Q36508817 | Bcl-2-family proteins and hematologic malignancies: history and future prospects |
| Q44817169 | Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation |
| Q40254604 | Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages |
| Q34328532 | Bcl-xL overexpression blocks bax-mediated mitochondrial contact site formation and apoptosis in rod photoreceptors of lead-exposed mice |
| Q34647032 | Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane |
| Q34310255 | Beta-amyloid oligomers activate apoptotic BAK pore for cytochrome c release. |
| Q39795113 | Bid cleavage, cytochrome c release and caspase activation in canine coronavirus-induced apoptosis |
| Q57036069 | Bid maintains mitochondrial cristae structure and protects against cardiac disease in an integrative genomics study |
| Q41990233 | Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria |
| Q42872841 | Bioelectric applications for treatment of melanoma |
| Q42157504 | Biphasic translocation of Bax to mitochondria |
| Q43148436 | Bisphenol A diglycidyl ether-induced apoptosis involves Bax/Bid-dependent mitochondrial release of apoptosis-inducing factor (AIF), cytochrome c and Smac/DIABLO. |
| Q34493785 | Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis |
| Q39985727 | Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture |
| Q36303053 | CD4 T cell-induced, bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responses. |
| Q34557066 | Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153. |
| Q37590186 | Calcium and cell death signaling in neurodegeneration and aging |
| Q28582648 | Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis |
| Q39674453 | Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis |
| Q24675708 | Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol |
| Q38827694 | Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner |
| Q36323125 | Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis |
| Q35129694 | Caspases and T lymphocytes: a flip of the coin? |
| Q24536096 | Caspases: pharmacological manipulation of cell death |
| Q38655649 | Cell Death Signaling |
| Q38061270 | Cellular and molecular mechanisms of mitochondrial function |
| Q35553007 | Cellular and molecular themes in apoptosis |
| Q40431685 | Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells |
| Q36073887 | Centipeda minima (Ebushicao) extract inhibits PI3K-Akt-mTOR signaling in nasopharyngeal carcinoma CNE-1 cells |
| Q45098480 | Changes in the messenger RNA expression levels of Bcl-2 family members and caspase-8 and -3 in porcine ovarian follicles during follicular atresia |
| Q44583784 | Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells |
| Q41128070 | Cholesterol effects on BAX pore activation |
| Q40007577 | Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway |
| Q36334357 | Cisplatin nephrotoxicity: molecular mechanisms. |
| Q40689887 | Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways |
| Q38964512 | Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines |
| Q43960770 | Coexistence of translocated cytochrome c and nitrated protein in neurons of the rat cerebral cortex after oxygen and glucose deprivation. |
| Q31117048 | Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activation |
| Q34549543 | Conformation of membrane-associated proapoptotic tBid |
| Q42156839 | Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers |
| Q41011587 | Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1. |
| Q28246420 | Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 |
| Q34102626 | Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer |
| Q37183557 | Current trends in multiple myeloma management |
| Q28396645 | Cytoprotection by the modulation of mitochondrial electron transport chain: the emerging role of mitochondrial STAT3 |
| Q24338613 | Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL |
| Q59135222 | Cytotoxic effect of Drimia maritima bulb extract and induction of mitochondrial apoptotic signaling in human breast cancer cells, MCF-7 and MDA-MB-468 |
| Q40534730 | Cytotoxic effects of mansonone E and F isolated from Ulmus pumila |
| Q39392134 | Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines |
| Q39354171 | DAP5 ameliorates cisplatin-induced apoptosis of renal tubular cells |
| Q34278532 | DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells |
| Q35815150 | DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis |
| Q28303251 | Death-associated protein-3, DAP-3, correlates with preoperative chemotherapy effectiveness and prognosis of gastric cancer patients following perioperative chemotherapy and radical gastrectomy. |
| Q92564995 | Decoding the sweet regulation of apoptosis: the role of glycosylation and galectins in apoptotic signaling pathways |
| Q92979430 | Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells |
| Q39792277 | Delineation of the molecular mechanisms of Francisella tularensis-induced apoptosis in murine macrophages |
| Q39987289 | Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of Bax. |
| Q33991174 | Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage |
| Q52014452 | Developmental cell death during Xenopus metamorphosis involves BID cleavage and caspase 2 and 8 activation. |
| Q35020663 | Differential effects of ethanol on bid, tBid, and Bax:tBid interactions in postnatal day 4 and postnatal day 7 rat cerebellum |
| Q43902939 | Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells |
| Q35553989 | Differential regulation of caspase-2 in MPP⁺-induced apoptosis in primary cortical neurons |
| Q38892896 | Direct effect of streptozotocin on periodontal ligament cells through myeloid cell leukemia-1. |
| Q34027884 | Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells. |
| Q73839402 | Divide et impera: Ca2+ signals, mitochondrial fission and sensitization to apoptosis |
| Q28387136 | Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases? |
| Q38023263 | Driving apoptosis-relevant proteins toward neural differentiation |
| Q33714735 | Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance |
| Q83094952 | Effects of phospholipids on the functional regulation of tBID in membranes |
| Q51065185 | Effects of selenium intervention on chronic fluorosis-induced renal cell apoptosis in rats. |
| Q39895438 | Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation |
| Q34306872 | Elucidating cytochrome C release from mitochondria: insights from an in silico three-dimensional model |
| Q33682689 | Emerging Bcl-2 inhibitors for the treatment of cancer |
| Q37494647 | Emerging drugs in the treatment of pancreatic cancer |
| Q36092385 | Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage |
| Q33848083 | Enhanced efficacy of photodynamic therapy via a sequential targeting protocol |
| Q40182110 | Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA-mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments. |
| Q34121293 | Epigallocatechin-3-gallate protects against cisplatin nephrotoxicity by inhibiting the apoptosis in mouse |
| Q42286702 | Ethanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain-derived neurotrophic factor |
| Q28511112 | Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain |
| Q44489218 | Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703. |
| Q28569153 | Evaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c release |
| Q34997430 | Expression of Bcl-2 family member Bid in normal and malignant tissues |
| Q36617005 | Expression of the proapoptotic protein Bid is an adverse prognostic factor for radiotherapy outcome in carcinoma of the cervix. |
| Q39918670 | Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line |
| Q24338213 | FAST is a BCL-X(L)-associated mitochondrial protein |
| Q33582047 | Facilitation of mitochondrial outer and inner membrane permeabilization and cell death in oxidative stress by a novel Bcl-2 homology 3 domain protein. |
| Q41291054 | Finding a Panacea among combination cancer therapies. |
| Q35599867 | Gene expression in early ischemic renal injury: clues towards pathogenesis, biomarker discovery, and novel therapeutics |
| Q77628113 | Genomic plasticity in cell death susceptibility |
| Q40019541 | Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by a new series of substituted-1,3,4-oxadiazole derivatives. |
| Q40212968 | Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells. |
| Q24305060 | Heterodimerization of BAK and MCL-1 activated by detergent micelles |
| Q24634709 | Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism |
| Q37317447 | High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition |
| Q37100016 | How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? |
| Q36394994 | How the Bcl-2 family of proteins interact to regulate apoptosis. |
| Q28118892 | Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak |
| Q47267139 | Humanin decreases mitochondrial membrane permeability by inhibiting the membrane association and oligomerization of Bax and Bid proteins. |
| Q35174027 | Hypothesis for a common basis for neuroprotection in glaucoma and Alzheimer's disease: anti-apoptosis by alpha-2-adrenergic receptor activation |
| Q37137685 | Hypoxia ischemia-mediated cell death in neonatal rat brain |
| Q46886564 | IFN-alpha induces barrier destabilization and apoptosis in renal proximal tubular epithelium |
| Q39946627 | Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis |
| Q24791108 | Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax |
| Q35195215 | Immune disorders caused by defects in the caspase cascade |
| Q37135532 | Immunological control of herpes simplex virus infections |
| Q50533091 | Importance of IL-6, MMP-1, IGF-1, and BAX Levels in Lumbar Herniated Disks and Posterior Longitudinal Ligament in Patients with Sciatic Pain. |
| Q81158200 | In vitro analysis of Bcl-2 proteins in mitochondria and endoplasmic reticulum: similarities in anti-apoptotic functions and differences in regulation |
| Q39826196 | In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures |
| Q36869591 | Inclusion Complex of Zerumbone with Hydroxypropyl- β -Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio |
| Q35184981 | Induction of GADD153 and Bak: novel molecular targets of fenretinide-induced apoptosis of neuroblastoma |
| Q44569027 | Induction of apoptosis in human hepatoblastoma cells by tetrandrine via caspase-dependent Bid cleavage and cytochrome c release |
| Q48731588 | Induction of proapoptotic gene expression and recruitment of p53 herald ovarian follicle loss caused by polycyclic aromatic hydrocarbons |
| Q34299265 | Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor |
| Q36135895 | Inhibition of MicroRNA-21 induces apoptosis in dermal fibroblasts of patients with systemic sclerosis |
| Q37745228 | Inhibition of autophagy blocks cathepsins-tBid-mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes |
| Q87421342 | Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway |
| Q33750838 | Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells |
| Q44205869 | Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. |
| Q43268599 | Interaction of the alpha-helical H6 peptide from the pro-apoptotic protein tBid with cardiolipin |
| Q82489816 | Interactions of Bax and tBid with lipid monolayers |
| Q37198666 | Interactions of PACAP and ceramides in the control of granule cell apoptosis during cerebellar development |
| Q91983879 | Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection |
| Q44526170 | Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax. |
| Q58201468 | Intersectin-1s Regulates the Mitochondrial Apoptotic Pathway in Endothelial Cells |
| Q40342717 | Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation |
| Q44567499 | Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases |
| Q33226642 | Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells |
| Q24538918 | Kaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis |
| Q31136038 | Ku70 suppresses the apoptotic translocation of Bax to mitochondria. |
| Q64923819 | LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells. |
| Q48368030 | Learning and cognitive deficits in hypoxic neonatal rats intensified by BAX mediated apoptosis: protective role of glucose, oxygen, and epinephrine |
| Q37233180 | Life and death by death receptors |
| Q36858872 | Life and death in peripheral T cells |
| Q24534937 | Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis |
| Q33228343 | Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma. |
| Q40598593 | Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway |
| Q44357715 | Low probability activation of Bax/Bak can induce selective killing of cancer cells by generating heterogeneity in apoptosis |
| Q90196428 | MSC.sTRAIL Has Better Efficacy than MSC.FL-TRAIL and in Combination with AKTi Blocks Pro-Metastatic Cytokine Production in Prostate Cancer Cells |
| Q38182480 | Manganese in health and disease |
| Q38185804 | Many players in BCL-2 family affairs |
| Q37389520 | Mapping the interaction of pro-apoptotic tBID with pro-survival BCL-XL. |
| Q34050464 | Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid. |
| Q26859211 | Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) |
| Q45224146 | Mechanism of mitochondrial stress-induced resistance to apoptosis in mitochondrial DNA-depleted C2C12 myocytes |
| Q34129759 | Mechanisms balancing skeletal matrix synthesis and degradation |
| Q42225309 | Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis |
| Q22242658 | Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS |
| Q37085889 | Mechanisms of apoptosis resistance and treatment strategies to overcome them in hormone-refractory prostate cancer |
| Q57082831 | Mechanisms of mitochondrial membrane permeabilization |
| Q42851591 | Melatonin or silymarin reduces maneb‐ and paraquat‐induced Parkinson’s disease phenotype in the mouse |
| Q26795759 | Metabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implication |
| Q38723197 | MicroRNA-190b confers radio-sensitivity through negative regulation of Bcl-2 in gastric cancer cells |
| Q52659036 | MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis. |
| Q92144036 | MicroRNAs in non-small cell lung cancer: Gene regulation, impact on cancer cellular processes, and therapeutic potential |
| Q37566211 | Mimicking the BH3 domain to kill cancer cells |
| Q40663259 | Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. |
| Q36733720 | Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II. |
| Q34956201 | Mitochondria and apoptosis: new therapeutic targets |
| Q35120743 | Mitochondria at the heart of the cytotoxic attack |
| Q35111543 | Mitochondria in apoptosis of ischemic heart |
| Q35058606 | Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling |
| Q35545214 | Mitochondria: a target for cancer therapy |
| Q36274960 | Mitochondria: pharmacological manipulation of cell death |
| Q34648793 | Mitochondria: regulating the inevitable. |
| Q28204466 | Mitochondrial Regulation of Apoptosis |
| Q42159376 | Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells |
| Q38201407 | Mitochondrial channels: ion fluxes and more |
| Q37800527 | Mitochondrial involvement in cell death of non-mammalian eukaryotes |
| Q35120714 | Mitochondrial membrane permeabilisation by Bax/Bak |
| Q37517187 | Mitochondrial targeting of tBid/Bax: a role for the TOM complex? |
| Q36558020 | Mitochondriotoxic compounds for cancer therapy |
| Q40599847 | Mitogen-activated protein kinase/extracellular signal-regulated kinase attenuates 3-hydroxykynurenine-induced neuronal cell death |
| Q36593116 | Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion. |
| Q34561618 | Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer |
| Q64079884 | Molecular dissection of box jellyfish venom cytotoxicity highlights an effective venom antidote |
| Q38796781 | Molecular mechanism of apoptosis induction by Gaillardin, a sesquiterpene lactone, in breast cancer cell lines : Gaillardin-induced apoptosis in breast cancer cell lines. |
| Q30414386 | Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma |
| Q51042371 | Monte Carlo simulations of tBid association with the mitochondrial outer membrane. |
| Q36179374 | Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis |
| Q35027903 | Motor neuron trophic factors: Therapeutic use in ALS? |
| Q33855218 | Mutations to bid cleavage sites protect hepatocytes from apoptosis after ischemia/reperfusion injury |
| Q39288182 | NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria. |
| Q33985202 | NF-kappaB is involved in SHetA2 circumvention of TNF-alpha resistance, but not induction of intrinsic apoptosis |
| Q39020252 | Necroptosis induced by RIPK3 requires MLKL but not Drp1. |
| Q90755987 | Neoantimycin F, a Streptomyces-Derived Natural Product Induces Mitochondria-Related Apoptotic Death in Human Non-Small Cell Lung Cancer Cells |
| Q46607372 | Neuroprotective effects of dimerumic acid and deferricoprogen from Monascus purpureus NTU 568-fermented rice against 6-hydroxydopamine-induced oxidative stress and apoptosis in differentiated pheochromocytoma PC-12 cells |
| Q36850257 | Neuroprotective strategies to avert seizure-induced neurodegeneration in epilepsy. |
| Q38699019 | New 6(17)-epoxylathyrane diterpene: aellinane from Euphorbia aellenii induces apoptosis via mitochondrial pathway in ovarian cancer cell line |
| Q36786048 | No life without death |
| Q35150716 | Nonredundant role of Bax and Bak in Bid-mediated apoptosis |
| Q38939392 | Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction. |
| Q38740285 | Nujiangexathone A, a Novel Compound Derived from Garcinia nujiangensis, Induces Caspase-Dependent Apoptosis in Cervical Cancer through the ROS/JNK Pathway. |
| Q38767747 | Oleanolic Acid Inhibits High Salt-Induced Exaggeration of Warburg-like Metabolism in Breast Cancer Cells |
| Q41980121 | Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress |
| Q44224227 | Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. |
| Q37257680 | Oncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane |
| Q34443559 | Organelle-specific initiation of cell death pathways |
| Q53862969 | Outer mitochondrial membrane permeabilization: an open-and-shut case? |
| Q36371958 | Overexpression of amyloid-β protein precursor induces mitochondrial oxidative stress and activates the intrinsic apoptotic cascade |
| Q33889618 | Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse. |
| Q40643972 | Oxidized low-density lipoprotein induces calpain-dependent cell death and ubiquitination of caspase 3 in HMEC-1 endothelial cells |
| Q33186742 | Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop |
| Q37778022 | Permeabilization of the Outer Mitochondrial Membrane by Bcl-2 Proteins |
| Q39386461 | Perturbing pro-survival proteins using quinoxaline derivatives: a structure-activity relationship study |
| Q40765687 | Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain |
| Q36213869 | Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis |
| Q88728607 | Phosphorylation alters Bim-mediated Mcl-1 stabilization and priming |
| Q39001169 | Phosphorylation of the proapoptotic BH3-only protein bid primes mitochondria for apoptosis during mitotic arrest |
| Q35987570 | Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis |
| Q53273558 | Piroxicam and C-phycocyanin mediated apoptosis in 1,2-dimethylhydrazine dihydrochloride induced colon carcinogenesis: exploring the mitochondrial pathway. |
| Q39384356 | Pore formation by dimeric Bak and Bax: an unusual pore? |
| Q44407039 | Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species |
| Q36490192 | Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities |
| Q36159265 | Programmed cell death in plant embryogenesis |
| Q28345086 | Propagation of the apoptotic signal by mitochondrial waves |
| Q34816073 | Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs |
| Q35846720 | Protecting mitochondrial bioenergetic function during resuscitation from cardiac arrest |
| Q39072850 | Protective role of dietary-supplemented selenium and vitamin E in heat-induced apoptosis and oxidative stress in mice testes |
| Q53488880 | Publications in cell death: the golden age. |
| Q40252560 | RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cells |
| Q39434384 | RNase MC2: a new Momordica charantia ribonuclease that induces apoptosis in breast cancer cells associated with activation of MAPKs and induction of caspase pathways |
| Q35233707 | Radish (Raphanus sativus L. leaf) ethanol extract inhibits protein and mRNA expression of ErbB(2) and ErbB(3) in MDA-MB-231 human breast cancer cells |
| Q33466758 | Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila |
| Q40615490 | Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells |
| Q46560330 | Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation |
| Q34407588 | Regulation and execution of programmed cell death in response to pathogens, stress and developmental cues |
| Q35574143 | Regulation of apoptosis by Bcl‐2 family proteins |
| Q73251268 | Regulation of apoptotic signaling pathways in hepatocytes in vivo |
| Q35063194 | Regulation of cardiac myocyte cell death |
| Q38256353 | Regulation of human neutrophil apoptosis and lifespan in health and disease |
| Q29037634 | Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus |
| Q34694788 | Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a |
| Q33752784 | Release of Cytochrome C from Bax Pores at the Mitochondrial Membrane |
| Q42059521 | Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage |
| Q63408385 | Remodeling for Demolition |
| Q34355580 | Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels. |
| Q36376406 | Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells |
| Q37297507 | Resveratrol attenuates acute kidney injury by inhibiting death receptor‑mediated apoptotic pathways in a cisplatin‑induced rat model |
| Q35146645 | Retracted: Histone Deacetylase Inhibitors Sensitize Lung Cancer Cells to Hyperthermia: Involvement of Ku70/SirT-1 in Thermo-Protection |
| Q89562799 | Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm |
| Q46387185 | RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis |
| Q37826384 | Role of Bcl-2 family proteins and caspases in the regulation of apoptosis. |
| Q37576944 | Role of Expression of Inflammatory Mediators in Primary and Recurrent Lumbar Disc Herniation |
| Q41114371 | Role of Programmed Cell Death in the Immunopathogenesis of Sepsis |
| Q35879762 | Role of membrane Hsp70 in radiation sensitivity of tumor cells |
| Q33819255 | Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis |
| Q36318650 | Rotaviral enterotoxin nonstructural protein 4 targets mitochondria for activation of apoptosis during infection |
| Q39798291 | Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family |
| Q48238237 | Schizandrin protects primary rat cortical cell cultures from glutamate-induced apoptosis by inhibiting activation of the MAPK family and the mitochondria dependent pathway |
| Q44427670 | Seizure-like activity leads to the release of BAD from 14-3-3 protein and cell death in hippocampal neurons in vitro. |
| Q44038797 | Selective inhibition of dipeptidyl peptidase I, not caspases, prevents the partial processing of procaspase-3 in CD3-activated human CD8(+) T lymphocytes |
| Q42149002 | Selenite sensitizes mitochondrial permeability transition pore opening in vitro and in vivo: a possible mechanism for chemo-protection |
| Q42172525 | Signaling Rho-kinase mediates inflammation and apoptosis in T cells and renal tubules in cisplatin nephrotoxicity |
| Q39199277 | Simulated microgravity increases myocardial susceptibility to ischemia-reperfusion injury via a deficiency of AMP-activated protein kinase |
| Q39800909 | Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation. |
| Q33538398 | Sonodynamically induced apoptosis by protoporphyrin IX on hepatoma-22 cells in vitro |
| Q36919811 | Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling |
| Q35113327 | Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells |
| Q28507532 | Spatial and temporal changes in Bax subcellular localization during anoikis |
| Q46122363 | Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells |
| Q53085881 | Sphingomyelin and phosphatidylcholine contrarily affect the induction of apoptosis in intestinal epithelial cells. |
| Q33673823 | Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1 |
| Q38268983 | Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. |
| Q34307368 | Study of PTPC composition during apoptosis for identification of viral protein target. |
| Q40419557 | Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression |
| Q39508803 | Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines |
| Q35756866 | TRAIL and NFkappaB signaling--a complex relationship |
| Q39263297 | TRAIL-NP hybrids for cancer therapy: a review. |
| Q75368334 | Targeting Bcl-xL in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced apoptosis while normal epithelial cells are protected by blockade of caspase 9 |
| Q38132274 | Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy |
| Q40597116 | Targeting and amplification of immune killing of tumor cells by pro-Smac |
| Q33831890 | Targeting mitochondria for resuscitation from cardiac arrest |
| Q38014808 | Targeting the B-cell lymphoma/leukemia 2 family in cancer |
| Q40440958 | Taurine chloramine, an oxidant derived from neutrophils, induces apoptosis in human B lymphoma cells through mitochondrial damage |
| Q53089642 | Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation. |
| Q36501189 | The Bax pore in liposomes, Biophysics |
| Q43010046 | The C-terminus of cytochrome b5 confers endoplasmic reticulum specificity by preventing spontaneous insertion into membranes |
| Q35091401 | The CD95(APO-1/Fas) DISC and beyond |
| Q64062357 | The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma |
| Q46921325 | The Ca²⁺-calmodulin-Ca²⁺/calmodulin-dependent protein kinase II signaling pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in isolated rat hepatocytes. |
| Q28397675 | The Effect of Growth Hormone Administration on the Regulation of Mitochondrial Apoptosis in-Vivo |
| Q60146180 | The Role of Death Receptor Signaling in Testicular Germ-Cell Apoptosis Triggered by Mono-(2-ethylhexyl) Phthalate (MEHP)-Induced Sertoli Cell Injury and Its Implications for Risk Assessment |
| Q64882605 | The Role of Efferocytosis in Autoimmune Diseases. |
| Q47940580 | The Role of Resveratrol in Cancer Therapy. |
| Q40330298 | The TRAF3-binding site of human molluscipox virus FLIP molecule MC159 is critical for its capacity to inhibit Fas-induced apoptosis |
| Q37347133 | The VDAC2-BAK rheostat controls thymocyte survival |
| Q42157330 | The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage |
| Q42860113 | The channel of death |
| Q44588827 | The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family |
| Q34330221 | The domains of apoptosis: a genomics perspective |
| Q36150746 | The dynamics of Bax channel formation: influence of ionic strength |
| Q31145966 | The effects of Ce6-mediated sono-photodynamic therapy on cell migration, apoptosis and autophagy in mouse mammary 4T1 cell line |
| Q40369800 | The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R |
| Q45402737 | The equine arteritis virus induces apoptosis via caspase-8 and mitochondria-dependent caspase-9 activation |
| Q35145898 | The evolution of cell death programs as prerequisites of multicellularity |
| Q37699101 | The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) protects cells against cold-shock-induced apoptosis by maintaining phosphorylation of protein kinase B (AKT) |
| Q35557641 | The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis. |
| Q57496758 | The mitochondrial pathway is involved in sodium fluoride (NaF)-induced renal apoptosis in mice |
| Q37163574 | The mitochondrial permeability transition pore and ischemia-reperfusion injury |
| Q38782511 | The molecular pathway of psoralidin-induced apoptosis in HepG2 cell line. |
| Q34212713 | The multidomain proapoptotic molecules Bax and Bak are directly activated by heat |
| Q24337594 | The permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosis |
| Q24536013 | The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum |
| Q34038716 | The rheostat in the membrane: BCL-2 family proteins and apoptosis |
| Q26827928 | The role of BH3-mimetic drugs in the treatment of pediatric hepatoblastoma |
| Q35129712 | The role of CD95 in the regulation of peripheral T-cell apoptosis |
| Q42938547 | The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid |
| Q36733723 | The role of the mitochondria in mediating cytotoxicity of anti-cancer therapies |
| Q38039293 | The secrets of the Bcl-2 family |
| Q36366626 | The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status |
| Q27642185 | The structure of a Bcl-xL/Bim fragment complex: implications for Bim function |
| Q36764882 | Therapeutic targets in the mitochondrial apoptotic pathway |
| Q38798849 | To Prime, or Not to Prime: That Is the Question |
| Q34427589 | Topological and functional properties of the small GTPases protein interaction network |
| Q33640395 | Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the death receptor pathway |
| Q36701541 | Tumor Necrosis Factor-α: Life and Death of Hepatocytes During Liver Ischemia/Reperfusion Injury |
| Q24291723 | Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K |
| Q30572057 | Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases |
| Q34239873 | Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate |
| Q39642126 | Tyrosine dephosphorylation is required for Bak activation in apoptosis |
| Q28203236 | Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria |
| Q39389766 | Understanding the mechanistic roles of 30Kc6 gene in apoptosis and specific productivity in antibody-producing Chinese hamster ovary cells. |
| Q41832270 | Up-regulation of Bcl-2 expression in cultured human lymphocytes after exposure to low doses of gamma radiation |
| Q28478856 | Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication |
| Q50105551 | Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development. |
| Q41764200 | VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release |
| Q55129102 | VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis. |
| Q36450079 | VDAC1: from structure to cancer therapy |
| Q41633850 | VDAC2-specific cellular functions and the underlying structure |
| Q51025972 | VDAC: the channel at the interface between mitochondria and the cytosol. |
| Q35234876 | Vaccination with dendritic cells transfected with BAK and BAX siRNA enhances antigen-specific immune responses by prolonging dendritic cell life |
| Q35082212 | Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation |
| Q35145651 | Viruses and the TNF-related cytokines, an evolving battle |
| Q41339709 | Vitamin K and its analogs: Potential avenues for prostate cancer management |
| Q34010724 | Vitamin K2-mediated apoptosis in cancer cells: role of mitochondrial transmembrane potential |
| Q52953268 | Xuezhikang () reduced renal cell apoptosis in streptozocin-induced diabetic rats through regulation of Bcl-2 family. |
| Q34166041 | p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins. |
| Q40533259 | p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L). |
| Q35993991 | p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection |
| Q42650397 | p53 regulates a non-apoptotic death induced by ROS. |
| Q46428278 | tBid interaction with cardiolipin primarily orchestrates mitochondrial dysfunctions and subsequently activates Bax and Bak. |
| Q39647132 | tcBid promotes Ca(2+) signal propagation to the mitochondria: control of Ca(2+) permeation through the outer mitochondrial membrane |
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