| Q46558903 | 3,4-Dideoxyglucosone-3-ene as a mediator of peritoneal demesothelization. |
| Q27933421 | A TSC22-like motif defines a novel antiapoptotic protein family. |
| Q35762470 | A means to a DNA end: the many roles of Ku. |
| Q27930573 | A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. |
| Q35096245 | A retention factor keeps death at bay. |
| Q35917067 | A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax. |
| Q24305337 | ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway |
| Q36435476 | ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. |
| Q35860422 | AcK-knowledge reversible acetylation |
| Q44800956 | Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis |
| Q81676592 | Activation of Bax by BH3 domains during apoptosis: the unfolding of a deadly plot |
| Q35868063 | Adult neuron survival strategies--slamming on the brakes |
| Q45229434 | Alterations in gene expression profiles and the DNA-damage response in ionizing radiation-exposed TK6 cells |
| Q41874223 | Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation |
| Q39223241 | Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene |
| Q37802459 | Anti-apoptosis and cell survival: A review |
| Q38924245 | Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer. |
| Q38228349 | Apoptosis and molecular targeting therapy in cancer |
| Q37028788 | Apoptosis commitment--translating survival signals into decisions on mitochondria |
| Q35580382 | Apoptosis in Yeasts |
| Q35611251 | Apoptosis in human cancer cells |
| Q35939765 | Apoptosis in unicellular organisms: mechanisms and evolution |
| Q34556301 | Apoptosis-based therapies for hematologic malignancies |
| Q35595541 | Apoptosis-like yeast cell death in response to DNA damage and replication defects |
| Q36226739 | Apoptotic pathways and therapy resistance in human malignancies |
| Q42806222 | Autoacetylation regulates P/CAF nuclear localization. |
| Q35666691 | B-cell homeostasis: digital survival or analog growth? |
| Q36501184 | BCL-2 in the crosshairs: tipping the balance of life and death |
| Q29617135 | BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly |
| Q46210526 | BH4 peptide derived from Bcl-xL and Bax-inhibitor peptide suppresses apoptotic mitochondrial changes in heat stressed bovine oocytes |
| Q40184170 | Balance of NF-kappaB and p38 MAPK is a determinant of radiosensitivity of the AML-2 and its doxorubicin-resistant cell lines |
| Q36464580 | Bax inhibiting peptide reduces apoptosis in neonatal rat hypoxic-ischemic brain damage |
| Q40517341 | Bax-inhibiting peptide derived from mouse and rat Ku70. |
| Q40015913 | Bax-inhibiting peptide protects glutamate-induced cerebellar granule cell death by blocking Bax translocation |
| Q36581944 | Bcl-2 family members and apoptosis, taken to heart |
| Q35680502 | Bcl-2 family members: integrators of survival and death signals in physiology and pathology [corrected]. |
| Q40263616 | Bcl-xL is overexpressed in hormone-resistant prostate cancer and promotes survival of LNCaP cells via interaction with proapoptotic Bak. |
| Q80480022 | Bcr-Abl-independent imatinib-resistant K562 cells show aberrant protein acetylation and increased sensitivity to histone deacetylase inhibitors |
| Q40012287 | Bif-1 and Bax expression in cutaneous Merkel cell carcinoma |
| Q34586913 | CLU blocks HDACI-mediated killing of neuroblastoma. |
| Q35855807 | CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A. |
| Q36628407 | CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma |
| Q37666719 | CRISPR/Cas9 mediated multiplex genome editing and heritable mutagenesis of BmKu70 in Bombyx mori |
| Q59053736 | CSI: cell biology |
| Q24297207 | Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase |
| Q40183178 | Camptothecin acts synergistically with imatinib and overcomes imatinib resistance through Bcr-Abl independence in human K562 cells |
| Q53123002 | Castration therapy results in decreased Ku70 levels in prostate cancer. |
| Q44463051 | Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis |
| Q36103553 | Cell death suppression by cytomegaloviruses |
| Q37779104 | Cell death targets and potential modulators in Alzheimer's disease |
| Q37377052 | Cell-cycle control in the face of damage--a matter of life or death. |
| Q36321042 | Cell-penetrating peptides: mechanisms and applications |
| Q40431685 | Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells |
| Q39197908 | Cerebral Dopamine Neurotrophic Factor: A Potential Therapeutic Agent for Parkinson's Disease |
| Q37234989 | Changes in the level and distribution of Ku proteins during cellular senescence. |
| Q33316131 | Characterisation of the Bax-nucleophosmin interaction: the importance of the Bax C-terminus |
| Q40132827 | Chromatin compaction and cell death by high molecular weight FGF-2 depend on its nuclear localization, intracrine ERK activation, and engagement of mitochondria |
| Q37625188 | Clusterin and chemoresistance |
| Q24316499 | Clusterin inhibits apoptosis by interacting with activated Bax |
| Q36099229 | Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef |
| Q37424410 | Conformational changes and protein stability of the pro-apoptotic protein Bax. |
| Q42156839 | Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers |
| Q36321947 | Conformational control of Bax localization and apoptotic activity by Pro168. |
| Q52162090 | Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection |
| Q35680504 | Control of mitochondrial permeability by Bcl-2 family members |
| Q44372585 | Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70. |
| Q39406288 | Cytosolic Bax: does it require binding proteins to keep its pro-apoptotic activity in check? |
| Q37396048 | Cytosolic Ku70 regulates Bax-mediated cell death |
| Q44548892 | Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons |
| Q55026780 | DNA binding activity of Ku during chemotherapeutic agent-induced early apoptosis. |
| Q40141826 | DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells |
| Q34312499 | DNA damage-induced apoptosis |
| Q40184751 | DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage |
| Q30392650 | DNA-binding protects p53 from interactions with cofactors involved in transcription-independent functions |
| Q35848414 | DSB repair: the yeast paradigm |
| Q36070078 | Death begets failure in the heart |
| Q39958000 | Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons. |
| Q28258456 | Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas |
| Q45182291 | Distinct domains control the addressing and the insertion of Bax into mitochondria. |
| Q79919035 | Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions |
| Q31036713 | Downregulation of genes involved in DNA repair and differential expression of transcription regulators and phosphatases precede IgM-induced apoptosis in the Burkitt's lymphoma cell line BL60-2. |
| Q51553657 | EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation. |
| Q44942734 | Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it. |
| Q82430042 | Effect of Ku proteins on IRES-mediated translation |
| Q33718637 | Effect of Ku70 expression on radiosensitivity in renal carcinoma 786-O cells |
| Q43147443 | Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. |
| Q58554232 | Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes |
| Q36078945 | Emerging beneficial roles of sirtuins in heart failure. |
| Q34622430 | Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA |
| Q90807481 | Enzymology of mitochondrial DNA repair |
| Q89589412 | Epidermal Growth Factor Receptor and its trafficking regulation by acetylation: Implication in resistance and exploring the newer therapeutic avenues in cancer |
| Q36094983 | Establishment of oocyte population in the fetal ovary: primordial germ cell proliferation and oocyte programmed cell death |
| Q44899425 | Expression of Bax in yeast affects not only the mitochondria but also vacuolar integrity and intracellular protein traffic. |
| Q36137282 | Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis |
| Q92578189 | FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma |
| Q36735596 | Functional hepatocyte culture and its application to cell therapies. |
| Q36324703 | GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway |
| Q37252345 | Genomic instability in cancer development |
| Q34590334 | Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70. |
| Q39977177 | HCCS1 overexpression induces apoptosis via cathepsin D and intracellular calcium, and HCCS1 disruption in mice causes placental abnormality |
| Q40972077 | HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension |
| Q101131868 | Hepatocyte-derived MANF is protective for rifampicin-induced cholestatic hepatic injury via inhibiting ATF4-CHOP signal activation |
| Q34385667 | Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein. |
| Q46902523 | Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib. |
| Q52579549 | Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation. |
| Q37595483 | Histone deacetylase inhibitors: current status and overview of recent clinical trials |
| Q42733201 | Host protein Ku70 binds and protects HIV-1 integrase from proteasomal degradation and is required for HIV replication |
| Q35538187 | Human and animal models of V(D)J recombination deficiency |
| Q91129510 | Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization |
| Q39873558 | Hypoxia inhibits pulmonary artery endothelial cell apoptosis via the e-selectin/biliverdin reductase pathway |
| Q48236968 | Hypoxia-induced retinal ganglion cell death and the neuroprotective effects of beta-adrenergic antagonists |
| Q35941589 | IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects |
| Q24319043 | Identification of ADP-ribosylation factor 4 as a suppressor of N-(4-hydroxyphenyl)retinamide-induced cell death |
| Q33343333 | Identification of cytochrome c oxidase subunit 6A1 as a suppressor of Bax-induced cell death by yeast-based functional screening |
| Q80032241 | Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast |
| Q85109351 | Identification of novel 14-3-3ζ interacting proteins by quantitative immunoprecipitation combined with knockdown (QUICK) |
| Q40157178 | Increase in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients' survival in glioblastoma multiforme |
| Q36089339 | Induction of apoptosis by curcumin and its implications for cancer therapy |
| Q89793752 | Inhibition of DNA Repair Protein Ku70 in High-Glucose Environment Aggravates the Neurotoxicity Induced by Bupivacaine in SH-SY5Y Cells |
| Q33840412 | Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor |
| Q28283531 | Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions |
| Q46477292 | Inhibition of insulin-like growth factor 1 receptor signaling enhanced silibinin-induced activation of death receptor and mitochondrial apoptotic pathways in human breast cancer MCF-7 cells |
| Q24296781 | Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis |
| Q80171583 | Interfering with programmed cell death in neurodegenerative diseases: insights from experimental animal models |
| Q39436702 | Intracellular trafficking and secretion of mouse mesencephalic astrocyte-derived neurotrophic factor. |
| Q40337882 | Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis |
| Q35835100 | Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells |
| Q40568858 | JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins |
| Q40278269 | JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells |
| Q38875298 | Just Look! Intravital Microscopy as the Best Means to Study Kidney Cell Death Dynamics |
| Q40420043 | Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells |
| Q49093624 | K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion |
| Q35532757 | KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair |
| Q36916054 | Ku protein levels, localization and association to replication origins in different stages of breast tumor progression. |
| Q39669198 | Ku70 acetylation in neuroblastoma pathogenesis and therapy |
| Q33935153 | Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors |
| Q37014937 | Ku70 functions in addition to nonhomologous end joining in pancreatic β-cells: a connection to β-catenin regulation |
| Q38718262 | Ku70 inhibits gemcitabine-induced DNA damage and pancreatic cancer cell apoptosis |
| Q53611242 | Ku70 is essential for histone deacetylase inhibitor trichostatin A-induced apoptosis. |
| Q40339315 | Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii |
| Q36566952 | Larger than life: Mitochondria and the Bcl-2 family |
| Q34143647 | Lipopolysaccharide protects primary B lymphocytes from apoptosis by preventing mitochondrial dysfunction and bax translocation to mitochondria |
| Q24534937 | Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis |
| Q35133357 | Malignant T cells in cutaneous T-cell lymphoma lesions contain decreased levels of the antiapoptotic protein Ku70 |
| Q39444667 | Maspin increases Ku70 acetylation and Bax-mediated cell death in cancer cells |
| Q27005855 | Melanocytorrhagy and apoptosis in vitiligo: connecting jigsaw pieces |
| Q38907342 | Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid |
| Q27665577 | Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons |
| Q48671883 | Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis |
| Q38311591 | MicroRNA-124 (miR-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion |
| Q27319928 | Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons. |
| Q36534322 | Mitochondria as the target of the pro-apoptotic protein Bax. |
| Q83309510 | Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1 |
| Q35545214 | Mitochondria: a target for cancer therapy |
| Q36274960 | Mitochondria: pharmacological manipulation of cell death |
| Q35876358 | Mitochondrial mechanisms of neural cell apoptosis |
| Q36396958 | Mitochondrial membrane permeabilization: the sine qua non for cell death |
| Q39646528 | Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status. |
| Q33286023 | Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damage |
| Q28575645 | Modulation of clusterin isoforms is associated with all-trans retinoic acid-induced proliferative arrest and apoptosis of intimal smooth muscle cells |
| Q83163585 | Molecular dynamics simulation and automated docking of the pro-apoptotic Bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70 |
| Q39965016 | Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks |
| Q91324151 | Myocardial protection properties of parishins from the roots of Gastrodia elata Bl |
| Q40545931 | Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak. |
| Q39958845 | NBS1 regulates a novel apoptotic pathway through Bax activation |
| Q40109955 | Nerve growth factor receptor TrkA signaling in breast cancer cells involves Ku70 to prevent apoptosis |
| Q34096169 | Neuronal apoptosis in cerebral ischemia/reperfusion area following electrical stimulation of fastigial nucleus |
| Q37301656 | Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon. |
| Q36497411 | New molecular markers in resistant B-CLL. |
| Q81325497 | Newcomers in the process of mitochondrial permeabilization |
| Q24815695 | Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor |
| Q28260337 | Non-homologous end-joining, a sticky affair |
| Q33261981 | Nucleophosmin is a novel Bax chaperone that regulates apoptotic cell death. |
| Q27937462 | Old yellow enzymes, highly homologous FMN oxidoreductases with modulating roles in oxidative stress and programmed cell death in yeast |
| Q38200316 | One ring to bring them all--the role of Ku in mammalian non-homologous end joining |
| Q42017634 | Oxidative DNA damage in neurons: implication of ku in neuronal homeostasis and survival |
| Q38248876 | P53 and Sirt1: routes of metabolism and genome stability |
| Q34048273 | P53 inhibition exacerbates late-stage anthracycline cardiotoxicity |
| Q53540619 | PKC delta in preeclamptic placentas promotes Bax dissociation from 14-3-3 zeta through 14-3-3 zeta phosphorylation. |
| Q36269561 | Paradigm shifts in radiation biology: their impact on intervention for radiation-induced disease |
| Q34763027 | Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning |
| Q37330218 | Peptides and peptide mimics as modulators of apoptotic pathways. |
| Q42115619 | Pharmacological manipulation of Bcl-2 family members to control cell death |
| Q37411656 | Physiological and pathophysiological functions of SIRT1. |
| Q51026762 | Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia. |
| Q52145827 | Pre-administration of BAX-inhibiting peptides decrease the loss of the nigral dopaminergic neurons in rats. |
| Q82420849 | Prevention of apoptosis by the interaction between FIH1 and Bax |
| Q36490192 | Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities |
| Q37194759 | Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians |
| Q37051197 | Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage. |
| Q46943425 | Prolonged survival of mice with acute liver failure with transplantation of monkey hepatocytes cultured with an antiapoptotic pentapeptide V5. |
| Q37800060 | Protein acetylation within the cellular response to radiation. |
| Q24324334 | Protein kinase C-epsilon protects MCF-7 cells from TNF-mediated cell death by inhibiting Bax translocation |
| Q80381782 | Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation |
| Q39907667 | Protein microarray analysis of apoptosis-related protein expression following heat shock in human tongue squamous cell carcinomas containing different p53 phenotypes |
| Q40282861 | Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation |
| Q35685794 | Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities. |
| Q40060992 | Quantum dot-induced epigenetic and genotoxic changes in human breast cancer cells |
| Q24319133 | RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL |
| Q93035884 | Radiation resistance of normal human astrocytes: the role of non-homologous end joining DNA repair activity |
| Q33358859 | Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells |
| Q33986185 | Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production |
| Q34567369 | Redox stress and the contributions of BH3-only proteins to infarction. |
| Q34568839 | Regulated cell death in AKI. |
| Q36181740 | Regulation of Bcl-2 proteins and of the permeability of the outer mitochondrial membrane. |
| Q35941815 | Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases. |
| Q40372997 | Regulation of the pancreatic duodenal homeobox-1 protein by DNA-dependent protein kinase |
| Q40561256 | Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens. |
| Q101451737 | Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling |
| Q80078428 | Retractions |
| Q37826384 | Role of Bcl-2 family proteins and caspases in the regulation of apoptosis. |
| Q40530783 | Role of JC virus agnoprotein in DNA repair |
| Q36475735 | Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo |
| Q37096249 | Role of apoptotic and necrotic cell death under physiologic conditions |
| Q43076952 | Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity. |
| Q112694245 | SETD4-mediated KU70 methylation suppresses apoptosis |
| Q28468625 | SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells |
| Q36775876 | SIRT1 and neuronal diseases |
| Q36390052 | SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox |
| Q38890803 | SIRT3 in cardiovascular diseases: Emerging roles and therapeutic implications. |
| Q24645120 | SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70 |
| Q58186684 | Selective suppression of a subset of Bax‐dependent neuronal death by a cell permeable peptide inhibitor of Bax, BIP |
| Q37032338 | Simplified apoptotic cascades |
| Q47745453 | Sirt1's complex roles in neuroprotection |
| Q59135273 | Sirt3 enhances glioma cell viability by stabilizing Ku70–BAX interaction |
| Q64132293 | Sirtuin 1 and oral cancer |
| Q27001553 | Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism |
| Q38133369 | Sirtuins in stress response: guardians of the genome. |
| Q37788712 | Sirtuins: common targets in aging and in neurodegeneration. |
| Q36908428 | Sirtuins: critical regulators at the crossroads between cancer and aging |
| Q34231198 | Small-molecule Bax agonists for cancer therapy |
| Q47638560 | Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions |
| Q34970771 | Sorting out functions of sirtuins in cancer |
| Q37150530 | Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer |
| Q35741474 | Subcellular targeting regulates the function of caspase-activated protein kinases in apoptosis |
| Q40222168 | Supernatant of bacterial fermented soybean induces apoptosis of human hepatocellular carcinoma Hep 3B cells via activation of caspase 8 and mitochondria |
| Q37030590 | Systematic screens for human disease genes, from yeast to human and back |
| Q33441616 | Targeted quantitative mass spectrometric identification of differentially expressed proteins between Bax-expressing and deficient colorectal carcinoma cells. |
| Q36557296 | Targeting the Bcl-2 family in cancer therapy |
| Q28592278 | The Bax N terminus is required for negative regulation by the mitogen-activated protein kinase kinase and Akt signaling pathways in T cells |
| Q84654319 | The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane insertion |
| Q35591695 | The Bcl-2 family: roles in cell survival and oncogenesis. |
| Q37366735 | The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation |
| Q52685992 | The DNA-repair Ku70 protein is located in the nucleus and tail of elongating spermatids in grasshoppers. |
| Q38385852 | The Ku heterodimer: function in DNA repair and beyond |
| Q37515701 | The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression. |
| Q43919127 | The Ku70 DNA-repair protein is involved in centromere function in a grasshopper species. |
| Q50772328 | The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair. |
| Q92257585 | The Potential Role of MicroRNA-124 in Cerebral Ischemia Injury |
| Q91364666 | The Regulatory Role of NAD in Human and Animal Cells |
| Q38805474 | The Role of Clusterin in Carcinogenesis and its Potential Utility as Therapeutic Target. |
| Q40138829 | The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells |
| Q28279631 | The Werner syndrome protein at the crossroads of DNA repair and apoptosis |
| Q36397520 | The biology of Ku and its potential oncogenic role in cancer. |
| Q98567790 | The disruption of protein-protein interactions as a therapeutic strategy for prostate cancer |
| Q34330221 | The domains of apoptosis: a genomics perspective |
| Q36058274 | The double life of the Ku protein: facing the DNA breaks and the extracellular environment. |
| Q37937462 | The dual role of sirtuins in cancer |
| Q38922527 | The effect of ionizing radiation on mRNA levels of the DNA damage response genes rad9, rad1 and hus1 in various mouse tissues |
| Q37398734 | The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology |
| Q44888432 | The establishment and characterization of cell lines stably expressing human Ku80 tagged with enhanced green fluorescent protein |
| Q28611423 | The intersection between DNA damage response and cell death pathways |
| Q28591419 | The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-m |
| Q35946473 | The mitochondrial death pathway and cardiac myocyte apoptosis |
| Q36799190 | The mitochondrial pathway in yeast apoptosis |
| Q64388329 | The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis |
| Q29547893 | The pathophysiology of mitochondrial cell death |
| Q37074968 | The pleiotropic effects of heterologous Bax expression in yeast. |
| Q45142484 | The role of Bax-inhibiting peptide in retinal ganglion cell apoptosis after optic nerve transection. |
| Q38039346 | The role of HDAC6 in Alzheimer's disease |
| Q35830410 | The role of the non-homologous end-joining pathway in lymphocyte development |
| Q36527717 | The role of the nonhomologous end-joining DNA double-strand break repair pathway in telomere biology |
| Q37122039 | Therapeutic role of sirtuins in neurodegenerative disease. |
| Q35680507 | There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum |
| Q34594349 | Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex |
| Q37625305 | Transcription-independent p53 apoptosis: an alternative route to death |
| Q36333195 | Transduction peptides within naturally occurring proteins |
| Q35618203 | Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells |
| Q40595329 | UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy |
| Q33696463 | USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated Apoptosis |
| Q46983937 | UVA/B-induced apoptosis in human melanocytes involves translocation of cathepsins and Bcl-2 family members |
| Q38899748 | Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential. |
| Q36011232 | Up-regulation of the Ku heterodimer in Drosophila testicular cyst cells |
| Q33631937 | Use of phage display to identify novel mineralocorticoid receptor-interacting proteins. |
| Q34333584 | Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility |
| Q36110191 | Yeast as a model for medical and medicinal research |
| Q33341392 | Yeast programmed cell death: an intricate puzzle |
| Q37468524 | Zebrafish as a model system to screen radiation modifiers |