| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/GLIA.22645 |
| P698 | PubMed publication ID | 24616078 |
| P50 | author | Yu Luo | Q51916694 |
| P2093 | author name string | Lei Yang | |
| Kazumi Ishidoh | |||
| Min Xu | |||
| Nobuhiko Katunuma | |||
| Yong Ni | |||
| Hui-Ling Zhang | |||
| Wei-Wei Gu | |||
| Jia-Guo Rong | |||
| Zhong-Sheng Li | |||
| P2860 | cites work | Lysosomal cysteine proteases: facts and opportunities | Q24535678 |
| Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors | Q27730182 | ||
| Cathepsin B | Q28245818 | ||
| Metallothionein-3 regulates lysosomal function in cultured astrocytes under both normal and oxidative conditions | Q28510613 | ||
| Triggering of apoptosis by cathepsins | Q59487845 | ||
| Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro | Q70136099 | ||
| Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo | Q70136102 | ||
| 37 Structure, properties, mechanisms, and assays ofcysteine protease inhibitors: Cystatins and E-64 derivatives | Q71999767 | ||
| In situ detection of DNA fragmentation after focal cerebral ischemia in mice | Q72135738 | ||
| Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
| Apoptosis in Ca2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activation | Q73265113 | ||
| CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury | Q73503153 | ||
| Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia | Q81012298 | ||
| Erythropoietin prevents nitric oxide and cathepsin-mediated neuronal death in focal brain ischemia | Q82612087 | ||
| Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: a widely used inhibitor of autophagy | Q83632609 | ||
| Neurotensin receptor involvement in the rise of extracellular glutamate levels and apoptotic nerve cell death in primary cortical cultures after oxygen and glucose deprivation | Q28574230 | ||
| Signaling pathway involved in hypoxia-inducible factor-1alpha regulation in hypoxic-ischemic cortical neurons in vitro. | Q33897337 | ||
| Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates | Q33935231 | ||
| Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy | Q33998182 | ||
| BH3-Only proteins-essential initiators of apoptotic cell death | Q34117362 | ||
| Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. | Q34139321 | ||
| Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex | Q34308086 | ||
| Structure-based development of specific inhibitors for individual cathepsins and their medical applications | Q34598268 | ||
| Astrocyte modulation of neurotoxic injury. | Q34984524 | ||
| Mechanisms, challenges and opportunities in stroke | Q35120144 | ||
| Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis | Q35163757 | ||
| Astrocyte influences on ischemic neuronal death. | Q35699525 | ||
| Ca2+-dependent proteases in ischemic neuronal death: a conserved 'calpain-cathepsin cascade' from nematodes to primates | Q35839939 | ||
| Ischemia-induced programmed cell death in astrocytes | Q36104649 | ||
| Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells. | Q36180675 | ||
| Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. | Q36717287 | ||
| Astrocyte metabolism and signaling during brain ischemia | Q36983687 | ||
| Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies. | Q37371403 | ||
| The role of lysosomal rupture in neuronal death | Q37601612 | ||
| Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia | Q40637230 | ||
| Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route | Q40843079 | ||
| Analysis of where and which types of proteinases participate in lysosomal proteinase processing using bafilomycin A1 and Helicobacter pylori Vac A toxin | Q42817555 | ||
| Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia | Q42987382 | ||
| Hyperthermic preconditioning protects astrocytes from ischemia/reperfusion injury by up-regulation of HIF-1 alpha expression and binding activity. | Q42990102 | ||
| Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia | Q43007194 | ||
| Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation | Q43511052 | ||
| Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells. | Q45269270 | ||
| Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats. | Q46070206 | ||
| Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death. | Q46098761 | ||
| Trichostatin A enhances OGD-astrocyte viability by inhibiting inflammatory reaction mediated by NF-kappaB. | Q46186057 | ||
| Lysosomal release of cathepsins causes ischemic damage in the rat hippocampal slice and depends on NMDA-mediated calcium influx, arachidonic acid metabolism, and free radical production. | Q46684542 | ||
| PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons | Q46870126 | ||
| Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'. | Q48388254 | ||
| Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. | Q48455875 | ||
| Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia | Q48568820 | ||
| Cathepsin B and middle cerebral artery occlusion in the rat. | Q48605509 | ||
| Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum | Q48619167 | ||
| High sensitivity of protoplasmic cortical astroglia to focal ischemia. | Q48663800 | ||
| Cathepsin B and phospo-JNK in relation to ongoing apoptosis after transient focal cerebral ischemia in the rat. | Q48695388 | ||
| A comparison of cathepsin B processing and distribution during neuronal death in rats following global ischemia or decapitation necrosis | Q48762283 | ||
| Dynamic changes of cathepsins B and L expression in the monkey hippocampus after transient ischemia | Q48861600 | ||
| P433 | issue | 6 | |
| P921 | main subject | astrocyte | Q502961 |
| cerebral infarction | Q1209150 | ||
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 855-880 | |
| P577 | publication date | 2014-02-24 | |
| P1433 | published in | Glia | Q15716658 |
| P1476 | title | Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway | |
| P478 | volume | 62 |
| Q48925750 | Atp13a2 Deficiency Aggravates Astrocyte-Mediated Neuroinflammation via NLRP3 Inflammasome Activation |
| Q57469837 | CID1067700, a late endosome GTPase Rab7 receptor antagonist, attenuates brain atrophy, improves neurologic deficits and inhibits reactive astrogliosis in rat ischemic stroke |
| Q61447778 | Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca-dependent PKC/p38MAPK/NF-κB pathway |
| Q98178387 | Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System |
| Q36676838 | Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration |
| Q55024687 | Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats. |
| Q37745228 | Inhibition of autophagy blocks cathepsins-tBid-mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes |
| Q90481993 | Ischemic Postconditioning Alleviates Cerebral Ischemia-Reperfusion Injury Through Activating Autophagy During Early Reperfusion in Rats |
| Q36954656 | Knockdown of cathepsin L sensitizes ovarian cancer cells to chemotherapy |
| Q100395013 | Lysosomal quality control of cell fate: a novel therapeutic target for human diseases |
| Q89848923 | The Role of Ubiquitin-Proteasome Pathway and Autophagy-Lysosome Pathway in Cerebral Ischemia |
| Q38657144 | The role of lysosome in cell death regulation |
| Q42181812 | Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis |
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