| scholarly article | Q13442814 |
| P356 | DOI | 10.1021/BI00014A037 |
| P698 | PubMed publication ID | 7718586 |
| P2093 | author name string | V Turk | |
| D Turk | |||
| R Huber | |||
| W Bode | |||
| N Katunuma | |||
| T Popovic | |||
| M Podobnik | |||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | crystal structure | Q895901 |
| P304 | page(s) | 4791-7 | |
| P577 | publication date | 1995-04-11 | |
| P1433 | published in | Biochemistry | Q764876 |
| P1476 | title | Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors | |
| P478 | volume | 34 |
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| Q44601532 | An assessment of protein–ligand binding site polarizability |
| Q36001094 | Autocatalytic processing of procathepsin B is triggered by proenzyme activity |
| Q58039002 | Binding modes of a new epoxysuccinyl–peptide inhibitor of cysteine proteases. Where and how do cysteine proteases express their selectivity? |
| Q44219923 | CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells |
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| Q38966313 | Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry |
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| Q43716338 | Cathepsins X and B display distinct activity profiles that can be exploited for inhibitor design |
| Q36862577 | Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides. |
| Q34943452 | Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection. |
| Q41845464 | Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. |
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| Q42846520 | Crystal structure of human cathepsin S. |
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| Q38964281 | Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling. |
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| Q33787274 | How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamics |
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| Q87421342 | Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway |
| Q77917014 | Inhibition of cysteine proteases by peptides containing aziridine-2,3-dicarboxylic acid building blocks |
| Q35187226 | Insights into the roles of cathepsins in antigen processing and presentation revealed by specific inhibitors |
| Q42167297 | LeView: automatic and interactive generation of 2D diagrams for biomacromolecule/ligand interactions |
| Q44068250 | Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer |
| Q24535678 | Lysosomal cysteine proteases: facts and opportunities |
| Q33857460 | Lysosomal cysteine proteases: more than scavengers |
| Q41506423 | Mechanism and regulation of bone resorption by osteoclasts. |
| Q40232980 | Molecular dynamics studies of caspase-3. |
| Q92948373 | Naphthalimide-Based Template for Inhibitor Screening via Cross-Linking and In-Gel Fluorescence: A Case Study against HCA II |
| Q27667908 | Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds |
| Q77376182 | Novel physiological functions of cathepsins B and L on antigen processing and osteoclastic bone resorption |
| Q43408830 | Optimization of peptidyl allyl sulfones as clan CA cysteine protease inhibitors |
| Q30848784 | Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates. |
| Q64079105 | Proteases Underground: Analysis of the Maize Root Apoplast Identifies Organ Specific Papain-Like Cysteine Protease Activity |
| Q28612038 | Proteolysis and antigen presentation by MHC class II molecules |
| Q38268345 | Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges |
| Q46286189 | Purification and characterization of cathepsin B-like cysteine protease from cotyledons of daikon radish, Raphanus sativus |
| Q54379041 | Recombinant expression, characterization and expressional analysis of clam Meretrix meretrix cathepsin B, an enzyme involved in nutrient digestion. |
| Q42157735 | S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B. |
| Q39488863 | SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis. |
| Q41718143 | Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs |
| Q31115693 | Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design |
| Q46388786 | Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases. |
| Q41770394 | Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells. |
| Q27664635 | Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft |
| Q27671668 | Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni |
| Q56591899 | Structural Basis for Possible Calcium-Induced Activation Mechanisms of Calpains |
| Q27639074 | Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex |
| Q42846000 | Structural determinants of specificity in the cysteine protease cruzain |
| Q73077056 | Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo |
| Q27636471 | Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases |
| Q24561952 | Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment |
| Q27733264 | Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion |
| Q40717671 | Structure-based development of cathepsin L inhibitors and therapeutic applications for prevention of cancer metastasis and cancer-induced osteoporosis. |
| Q34598268 | Structure-based development of specific inhibitors for individual cathepsins and their medical applications |
| Q34174553 | Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. |
| Q74173020 | Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors |
| Q36326605 | Targeting Cathepsin B for Cancer Therapies |
| Q44809737 | The 2.0 A crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm |
| Q27639638 | The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators |
| Q28237390 | The crystal structure of human cathepsin L complexed with E-64 |
| Q27733966 | The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft |
| Q36862775 | The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment |
| Q44529747 | Vito Turk--30 years of research on cysteine proteases and their inhibitors. |
| Q74452039 | X-ray crystal structure of papain complexed with cathepsin B-specific covalent-type inhibitor: substrate specificity and inhibitory activity |
| Q61066436 | aziridinyl peptides as inhibitors of cysteine proteases: Effect of a free carboxylic acid function on inhibition |
| Q44188806 | pH Dependence of inhibitors targeting the occluding loop of cathepsin B. |
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