Structure-based development of specific inhibitors for individual cathepsins and their medical applications

scientific article

Structure-based development of specific inhibitors for individual cathepsins and their medical applications is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.2183/PJAB.87.29
P932PMC publication ID3043741
P698PubMed publication ID21321479
P5875ResearchGate publication ID49836455

P2093author name stringNobuhiko Katunuma
P2860cites workChymostatin, a new chymotrypsin inhibitor produced by actinomycetesQ71527152
37 Structure, properties, mechanisms, and assays ofcysteine protease inhibitors: Cystatins and E-64 derivativesQ71999767
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivoQ73077056
Structure-based development of pyridoxal propionate derivatives as specific inhibitors of cathepsin K in vitro and in vivoQ73445387
Inhibition of intracellular cathepsin activities and suppression of immune responses mediated by helper T lymphocyte type-2 by peroral or intraperitoneal administration of vitamin B6Q73937042
Critical role of cathepsin-inhibitors for autoantigen processing and autoimmunityQ81100641
IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cellsQ81476292
Lysosomal cysteine proteases: facts and opportunitiesQ24535678
Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complexQ27620728
The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificityQ27651464
Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitorsQ27730182
Cathepsin S inhibitor prevents autoantigen presentation and autoimmunityQ28591251
Cathepsin L activity controls adipogenesis and glucose toleranceQ34654358
Action of rat liver cathepsin L on collagen and other substratesQ42167985
Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cellsQ43857553
Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major.Q54033906
Switch of CD4+ T cell differentiation from Th2 to Th1 by treatment with cathepsin B inhibitor in experimental leishmaniasis.Q54126242
Biosynthesis of leupeptinQ67276489
Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophagesQ68325548
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitroQ70136099
In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorptionQ70407077
Inhibitions by E-64 derivatives of rat liver cathepsin B and cathepsin L in vitro and in vivoQ71479486
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectenzymeQ8047
mechanism of actionQ3271540
P304page(s)29-39
P577publication date2011-01-01
P1433published inProceedings of the Japan Academy, Series BQ2675209
P1476titleStructure-based development of specific inhibitors for individual cathepsins and their medical applications
P478volume87

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cites work (P2860)
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Q39004902Calpain research for drug discovery: challenges and potential
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Q39106632Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids
Q36218199Cathepsin L targeting in cancer treatment.
Q51498595Clinical Impact of Cystatin C/Cathepsin L and Follistatin/Activin A Systems in Breast Cancer Progression: A Preliminary Report.
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Q87421342Inhibition of cysteine cathepsin B and L activation in astrocytes contributes to neuroprotection against cerebral ischemia via blocking the tBid-mitochondrial apoptotic signaling pathway
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