The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

scientific article

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1460-2075.1991.TB07771.X
P932PMC publication ID452927
P698PubMed publication ID1868826

P2093author name stringV Turk
D Turk
R Huber
D Musil
D Zucic
D. Musil
D. Turk
D. Zucic
I Mayr
I. Mayr
N Katunuma
N. Katunuma
R A Engh
R. Huber
R.A. Engh
T Popovic
T Towatari
T. Popovic
T. Towatari
V. Turk
P2860cites workL-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and LQ24531160
???Q28362284
The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interactionQ24556546
Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAsQ24629322
The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinasesQ27728538
Structure of papain refined at 1.65 A resolutionQ27729147
Binding of chloromethyl ketone substrate analogues to crystalline papainQ27749019
Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical featuresQ27860675
On the size of the active site in proteases. I. PapainQ27860826
Cathepsin B, Cathepsin H, and cathepsin LQ28277583
Cathepsin B and cystatins: evidence for a role in cancer progressionQ28297146
Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelainQ28306293
Gene structure of mouse cathepsin B.Q34135867
A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papainQ34366212
Cysteinyl proteinases and their selective inactivationQ34656277
Isolation of a cDNA clone for the human lysosomal proteinase cathepsin BQ35602619
A new purification procedure of human kidney cathepsin H, its properties and kinetic dataQ36439062
Homology of amino acid sequences of rat liver cathepsins B and H with that of papainQ37614945
Crystallization and Properties of Cathepsin B from Rat LiverQ39292520
Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and aQ41822276
Degradation of fructose-1,6-bisphosphate aldolase by cathepsin B.Q42168981
Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatinQ42848203
The specificity of cathepsin B. Hydrolysis of glucagon at the C-terminus by a peptidyldipeptidase mechanismQ42933088
Amino acid sequence of bovine spleen cathepsin BQ44186952
Preferential action of rat brain cathepsin B as a peptidyl dipeptidase converting pro-opioid oligopeptidesQ44349569
Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B.Q44639948
A comparison of the heme binding pocket in globins and cytochrome b5Q52868606
An exploration of the primary specificity site of cathepsin B.Q54346371
Crystal and molecular structure of the sulfhydryl protease calotropin DI at 3·2 Å resolutionQ57973654
Structure of actinidin, after refinement at 1.7 A resolutionQ67247280
Chromophoric and fluorophoric peptide substrates cleaved through the dipeptidyl carboxypeptidase activity of cathepsin BQ68209597
Biosyntheses and processing of lysosomal cysteine proteinases in rat macrophagesQ68325544
Crystallization of recombinant rat cathepsin BQ68499647
Porcine spleen cathepsin B is an exopeptidaseQ68884336
Disulfide bridges of bovine spleen cathepsin BQ68895366
N-terminal variants of recombinant stefin B: effect on affinity for papain and cathepsin BQ68920135
Intracellular transport and processing of lysosomal cathepsin BQ69439746
Amino acid sequence of human liver cathepsin BQ70059554
The specificity of cathepsin BQ71109630
Extracellular presence of the lysosomal proteinase cathepsin B in rheumatoid synovium and its activity at neutral pHQ71347962
Cathepsins B and H from porcine spleen. Purification, polypeptide chain arrangements, and carbohydrate contentQ71431072
Inhibitions by E-64 derivatives of rat liver cathepsin B and cathepsin L in vitro and in vivoQ71479486
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
X-ray crystallographyQ826582
P304page(s)2321-2330
2321-30
P577publication date1991-09-01
P1433published inThe EMBO JournalQ1278554
P1476titleThe refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity
P478volume10

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