scholarly article | Q13442814 |
P2093 | author name string | Vito Turk | |
Tao Sun | |||
Dušan Turk | |||
Miha Renko | |||
Boris Turk | |||
Veronika Stoka | |||
Olga Vasiljeva | |||
P2860 | cites work | Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization | Q22008028 |
Hallmarks of Cancer: The Next Generation | Q22252312 | ||
Cloning a synthetic gene for human stefin B and its expression in E. coli | Q22254878 | ||
Structural basis for the recognition and cleavage of histone H3 by cathepsin L | Q24293301 | ||
Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids | Q24299090 | ||
The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors | Q24300962 | ||
Cystatin C modulates cerebral beta-amyloidosis | Q24300978 | ||
The proteome of lysosomes | Q24303943 | ||
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis | Q24305291 | ||
Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location | Q24310097 | ||
Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas | Q24310447 | ||
Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor | Q24312357 | ||
Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin | Q24527331 | ||
Evolutionary families of peptidase inhibitors | Q24530704 | ||
Lysosomal cysteine proteases: facts and opportunities | Q24535678 | ||
The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction | Q24556546 | ||
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment | Q24561952 | ||
Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis | Q24632017 | ||
MEROPS: the peptidase database | Q24644757 | ||
Friends and relations of the cystatin superfamily--new members and their evolution | Q24673719 | ||
Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages | Q24676370 | ||
Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L | Q24678337 | ||
Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S. | Q27617244 | ||
Crystal structure of wild-type human procathepsin K | Q27617382 | ||
Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis. | Q33843319 | ||
Lysosomal cysteine proteases: more than scavengers | Q33857460 | ||
Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen | Q33858403 | ||
Human cathepsin X: A cysteine protease with unique carboxypeptidase activity | Q33875510 | ||
Proteolysis in MHC class II antigen presentation: who's in charge? | Q33885986 | ||
Boophilus microplus cathepsin L-like (BmCL1) cysteine protease: specificity study using a peptide phage display library | Q33887709 | ||
Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer. | Q33890759 | ||
Hereditary cystatin C amyloid angiopathy | Q33937075 | ||
Cathepsin K deficiency in mice induces structural and metabolic changes in the central nervous system that are associated with learning and memory deficits | Q33973023 | ||
Identification, characterization and localization of chagasin, a tight-binding cysteine protease inhibitor in Trypanosoma cruzi. | Q34102897 | ||
Protease degradomics: a new challenge for proteomics | Q34136618 | ||
Lysosomes revisited | Q34255304 | ||
Human cystatin, a new protein inhibitor of cysteine proteinases | Q34257291 | ||
Protein inhibitors of cysteine proteinases. III. Amino-acid sequence of cystatin from chicken egg white | Q34265764 | ||
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis | Q34320916 | ||
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages. | Q34326413 | ||
Characterization of the type-1 repeat from thyroglobulin, a cysteine-rich module found in proteins from different families | Q34396220 | ||
The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics | Q34416331 | ||
Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes | Q34422070 | ||
The lysosome turns fifty | Q34447595 | ||
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis | Q34471105 | ||
Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation | Q34478046 | ||
Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate | Q34523628 | ||
Molecular genetics of the NCLs -- status and perspectives | Q34545774 | ||
Targeting proteases: successes, failures and future prospects | Q34563752 | ||
Structural organization of the human kininogen gene and a model for its evolution | Q34564387 | ||
RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties | Q34576631 | ||
Cysteine cathepsins and the cutting edge of cancer invasion | Q34605340 | ||
Cathepsin L activity controls adipogenesis and glucose tolerance | Q34654358 | ||
Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease | Q34713891 | ||
Delivering nanomedicine to solid tumors | Q34726981 | ||
Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators | Q34754105 | ||
Imaging proteolysis by living human breast cancer cells | Q34786084 | ||
Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases | Q68760971 | ||
Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin | Q68822977 | ||
Collagenolytic cathepsins of rabbit spleen: a kinetic analysis of collagen degradation and inhibition by chicken cystatin | Q69420750 | ||
Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes | Q69505828 | ||
Genealogy of mammalian cysteine proteinase inhibitors. Common evolutionary origin of stefins, cystatins and kininogens | Q69913137 | ||
Mechanism of inhibition of papain by chicken egg white cystatin. Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor | Q69948361 | ||
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro | Q70136099 | ||
Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo | Q70136102 | ||
Bovine stefin C, a new member of the stefin family | Q70636054 | ||
Participation of cathepsin L on bone resorption | Q70670024 | ||
Lysosomal cathepsin B: correlation with metastatic potential | Q70777196 | ||
Rheumatoid arthritis | Q71046923 | ||
Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases | Q71185919 | ||
Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases | Q71365991 | ||
Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer | Q71782469 | ||
Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins | Q71935429 | ||
Role of the occluding loop in cathepsin B activity | Q71973705 | ||
Inhibition of cruzipain, the major cysteine proteinase of the protozoan parasite, Trypanosoma cruzi, by proteinase inhibitors of the cystatin superfamily | Q71994730 | ||
Kinetics of the pH-induced inactivation of human cathepsin L | Q72067273 | ||
Structural dissection of the multidomain kininogens. Fine mapping of the target epitopes of antibodies interfering with their functional properties | Q72077110 | ||
Potent inactivation of cathepsins S and L by peptidyl (acyloxy)methyl ketones | Q72159778 | ||
Identification of bovine stefin A, a novel protein inhibitor of cysteine proteinases | Q72589659 | ||
The affinity-labelling of cathepsin S with peptidyl diazomethyl ketones. Comparison with the inhibition of cathepsin L and calpain | Q72615845 | ||
Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney | Q72709864 | ||
Kinetics of inhibition of bovine cathepsin S by bovine stefin B | Q72787152 | ||
Serum cathepsin B levels and urinary excretion of cathepsin B in the cancer patients with remote metastasis | Q72828702 | ||
Human cathepsin B is a metastable enzyme stabilized by specific ionic interactions associated with the active site | Q72891339 | ||
Potency and selectivity of inhibition of cathepsin K, L and S by their respective propeptides | Q73023870 | ||
Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex | Q27620728 | ||
Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine | Q27621210 | ||
Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease | Q27622021 | ||
Crystal structure of human cathepsin V | Q27627428 | ||
Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping | Q27630854 | ||
Tetrameric dipeptidyl peptidase I directs substrate specificity by use of the residual pro-part domain | Q27635416 | ||
Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases | Q27636471 | ||
Structure of a Cys25-->Ser mutant of human cathepsin S | Q27637974 | ||
The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators | Q27639638 | ||
Crystal structure of Stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases | Q27640485 | ||
Essential role of proline isomerization in stefin B tetramer formation | Q27643513 | ||
The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family | Q27644771 | ||
The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity | Q27651464 | ||
The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex | Q27651504 | ||
Dipeptidyl nitrile inhibitors of Cathepsin L | Q27655858 | ||
Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft | Q27664635 | ||
Structure-Activity Analysis of Cathepsin K/Chondroitin 4-Sulfate Interactions | Q27666421 | ||
The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases | Q27728538 | ||
Structure of papain refined at 1.65 A resolution | Q27729147 | ||
Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors | Q27730182 | ||
The three-dimensional solution structure of human stefin A | Q27730383 | ||
Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide | Q27732677 | ||
Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion | Q27733264 | ||
Crystal structure of human cathepsin K complexed with a potent inhibitor | Q27734780 | ||
Crystal structure of human osteoclast cathepsin K complex with E-64 | Q27734783 | ||
Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen | Q27743415 | ||
Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: assays with human cathepsin B. | Q31130955 | ||
Human cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions | Q32021129 | ||
Expression of cathepsins B and S in the progression of prostate carcinoma | Q32160033 | ||
Substrate activity screening: a fragment-based method for the rapid identification of nonpeptidic protease inhibitors | Q33226393 | ||
Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities | Q33235638 | ||
Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain | Q33262483 | ||
Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites | Q33337380 | ||
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer. | Q33350682 | ||
Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions | Q33505847 | ||
Novel peptidyl aryl vinyl sulfones as highly potent and selective inhibitors of cathepsins L and B. | Q33638719 | ||
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. | Q33664639 | ||
Stefin B interacts with histones and cathepsin L in the nucleus | Q33744431 | ||
Cystatin C deficiency promotes epidermal dysplasia in K14-HPV16 transgenic mice | Q33749964 | ||
How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamics | Q33787274 | ||
Regulation of proteolytic activity in tissues | Q40575091 | ||
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins | Q40622338 | ||
Functional involvement of cathepsin W in the cytotoxic activity of NK‐92 cells | Q40629022 | ||
Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors | Q40652154 | ||
Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B. | Q40754112 | ||
Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype | Q40787027 | ||
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route | Q40843079 | ||
Inhibitory effects of antisense cathepsin B cDNA transfection on invasion and motility in a human osteosarcoma cell line | Q40910869 | ||
Invariant chain structure and MHC class II function | Q40968427 | ||
The discovery of lysosomes | Q41438482 | ||
Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors | Q41482008 | ||
Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes | Q41541087 | ||
Proregion structure of members of the papain superfamily. Mode of inhibition of enzymatic activity | Q41710645 | ||
Thyropins--new structurally related proteinase inhibitors. | Q41730400 | ||
Revised definition of substrate binding sites of papain-like cysteine proteases | Q41730414 | ||
Calpain inhibition by peptide epoxides | Q41761276 | ||
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue | Q41845012 | ||
Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. | Q41845464 | ||
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues | Q41849893 | ||
Quantifying cathepsin S activity in antigen presenting cells using a novel specific substrate | Q41852752 | ||
Cathepsin K: a cysteine protease with unique kinin-degrading properties | Q41873108 | ||
Interaction of chicken cystatin with inactivated papains | Q41878875 | ||
S3 to S3' subsite specificity of recombinant human cathepsin K and development of selective internally quenched fluorescent substrates | Q41888215 | ||
Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme | Q42064898 | ||
E64 [trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane] analogues as inhibitors of cysteine proteinases: investigation of S2 subsite interactions | Q42084932 | ||
The inactivation of the cysteinyl exopeptidases cathepsin H and C by affinity-labelling reagents | Q42112501 | ||
Histone H3 tail clipping regulates gene expression | Q42159557 | ||
The S2 subsites of cathepsins K and L and their contribution to collagen degradation | Q42160204 | ||
Resistance of cathepsin L compared to elastase to proteolysis when complexed with the serpin endopin 2C, and recovery of cathepsin L activity | Q42171555 | ||
The combined action of two enzymes in human serum can mimic the activity of cathepsin B. | Q42248043 | ||
Membrane type I-matrix metalloproteinase-mediated degradation of type I collagen by oral squamous cell carcinoma cells. | Q42508689 | ||
The occluding loop of cathepsin B prevents its effective inhibition by human kininogens. | Q42663543 | ||
Cathepsin L increases invasion and migration of B16 melanoma | Q42757004 | ||
Dynamic imaging of protease activity with fluorescently quenched activity-based probes. | Q42806191 | ||
An intracellular form of cathepsin B contributes to invasiveness in cancer. | Q42829858 | ||
High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen. | Q42844879 | ||
Human low-Mr kininogen contains three copies of a cystatin sequence that are divergent in structure and in inhibitory activity for cysteine proteinases | Q42852932 | ||
Nomenclature and classification of the proteins homologous with the cysteine-proteinase inhibitor chicken cystatin. | Q42853691 | ||
Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L. | Q42981725 | ||
Probing cathepsin K activity with a selective substrate spanning its active site. | Q43003155 | ||
Conformational flexibility and allosteric regulation of cathepsin K. | Q43070071 | ||
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis | Q43151758 | ||
Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation | Q43158721 | ||
Improvement of cathepsin S detection using a designed FRET peptide based on putative natural substrates | Q43203232 | ||
Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding | Q43277216 | ||
Cathepsin B activity regulation. Heparin-like glycosaminogylcans protect human cathepsin B from alkaline pH-induced inactivation. | Q43507844 | ||
Cyclic ketone inhibitors of the cysteine protease cathepsin K. | Q43550009 | ||
Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis | Q43591458 | ||
Human recombinant pro-dipeptidyl peptidase I (cathepsin C) can be activated by cathepsins L and S but not by autocatalytic processing | Q43591595 | ||
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor | Q43660551 | ||
Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method | Q43773668 | ||
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer | Q44068250 | ||
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer. | Q44103830 | ||
Determination of cathepsin B expression may offer additional prognostic information for ovarian cancer patients | Q44219922 | ||
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro | Q44312060 | ||
Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model. | Q44442851 | ||
Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B. | Q44639948 | ||
Regulation of collagenase activities of human cathepsins by glycosaminoglycans | Q44674022 | ||
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV. | Q44732185 | ||
Cysteine cathepsins (proteases)--on the main stage of cancer? | Q44897180 | ||
Comprehensive search for cysteine cathepsins in the human genome | Q44935351 | ||
Peptidyl allyl sulfones: a new class of inhibitors for clan CA cysteine proteases | Q45047073 | ||
Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee | Q34974325 | ||
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function | Q34996827 | ||
Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design. | Q35021901 | ||
Development of activity-based probes for cathepsin X. | Q35053426 | ||
A new subgroup of the family 2 cystatins | Q35088033 | ||
High molecular weight kininogen activates B2 receptor signaling pathway in human vascular endothelial cells | Q35107342 | ||
Functions of Propeptide Parts in Cysteine Proteases | Q35552225 | ||
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo | Q35558255 | ||
Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets? | Q35572201 | ||
Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation | Q35747144 | ||
Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival | Q35833961 | ||
Cysteine cathepsins in human cancer | Q35970409 | ||
Autocatalytic processing of procathepsin B is triggered by proenzyme activity | Q36001094 | ||
Lysosomal cysteine proteases: structural features and their role in apoptosis | Q36203712 | ||
Two distinct gene subfamilies within the family of cysteine protease genes | Q36216964 | ||
The lysosomal cysteine proteases in MHC class II antigen presentation | Q36266499 | ||
Drug delivery strategies for cathepsin inhibitors in joint diseases | Q36316921 | ||
Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands | Q36370268 | ||
Cysteine cathepsins in the immune response | Q36467439 | ||
Cysteine cathepsins: multifunctional enzymes in cancer | Q36600996 | ||
The molecular understanding of osteoclast differentiation | Q36650749 | ||
Inhibition of bone resorption by selective inactivators of cysteine proteinases | Q36710669 | ||
Role of cathepsin K in normal joints and in the development of arthritis | Q36737790 | ||
Emerging roles of cysteine cathepsins in disease and their potential as drug targets. | Q36740577 | ||
Emerging role of cathepsin S in obesity and its associated diseases | Q36766860 | ||
Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts | Q36800896 | ||
Cathepsin cysteine proteases in cardiovascular disease. | Q36830621 | ||
Protease signalling in cell death: caspases versus cysteine cathepsins. | Q36838143 | ||
Lysosomal cysteine cathepsins: signaling pathways in apoptosis | Q36841861 | ||
Autocatalytic activation of human cathepsin K. | Q36861164 | ||
Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells | Q36914323 | ||
Cysteine cathepsins: cellular roadmap to different functions | Q36934250 | ||
Biochemical properties and regulation of cathepsin K activity | Q36970827 | ||
Two decades of thyroglobulin type-1 domain research. | Q36988309 | ||
A fragment of the major histocompatibility complex class II-associated p41 invariant chain inhibits cruzipain, the major cysteine proteinase from Trypanosoma cruzi | Q73025834 | ||
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
Equistatin, a new inhibitor of cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain | Q73343314 | ||
Cathepsin B-like activity as a serum tumour marker in ovarian carcinoma | Q73374461 | ||
Binding mode of CA074, a specific irreversible inhibitor, to bovine cathepsin B as determined by X-ray crystal analysis of the complex | Q73436746 | ||
Structure-based development of pyridoxal propionate derivatives as specific inhibitors of cathepsin K in vitro and in vivo | Q73445387 | ||
Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L, and other clinical indicators | Q73483295 | ||
Equistatin, a protease inhibitor from the sea anemone actinia equina, is composed of three structural and functional domains | Q73556510 | ||
Selective induction of the secretion of cathepsins B and L by cytokines in synovial fibroblast-like cells | Q73582840 | ||
Cathepsins B and L in synovial fluids from patients with rheumatoid arthritis and the effect of cathepsin B on the activation of pro-urokinase | Q73601904 | ||
Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation | Q73723925 | ||
E-64 analogues as inhibitors of cathepsin B. On the role of the absolute configuration of the epoxysuccinyl group | Q73837899 | ||
The inhibition of cathepsin S by its propeptide--specificity and mechanism of action | Q74166240 | ||
Substrate/propeptide-derived endo-epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors | Q74173020 | ||
Biochemical characterization of human cathepsin X revealed that the enzyme is an exopeptidase, acting as carboxymonopeptidase or carboxydipeptidase | Q74198942 | ||
Cathepsin B and tumor-associated laminin expression in the progression of colorectal adenoma to carcinoma | Q77162078 | ||
Synthesis of peptide aldehyde derivatives as selective inhibitors of human cathepsin L and their inhibitory effect on bone resorption | Q77449793 | ||
MEROPS: the peptidase database | Q77660649 | ||
Cystatin B: mutation detection, alternative splicing and expression in progressive myclonus epilepsy of Unverricht-Lundborg type (EPM1) patients | Q79144720 | ||
Selective inhibition of the collagenase activity of cathepsin K | Q80140006 | ||
Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes | Q80207375 | ||
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation | Q82733740 | ||
A structural network associated with the kallikrein-kinin and renin-angiotensin systems | Q83017881 | ||
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting | Q83704514 | ||
Serum cathepsin-B levels and urinary-excretion of cathepsin-B in the patients with colorectal-cancer - possible indicators for tumor malignancy | Q84089175 | ||
Azepanone-based inhibitors of human cathepsin S: optimization of selectivity via the P2 substituent | Q84512759 | ||
Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L. | Q45060723 | ||
Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo | Q45231987 | ||
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans | Q45264641 | ||
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. | Q46006433 | ||
Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs | Q46187663 | ||
Cathepsin X binds to cell surface heparan sulfate proteoglycans | Q46409838 | ||
Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms | Q46477376 | ||
Localization of DNA sequences governing alternative mRNA production of rat kininogen genes | Q46571738 | ||
Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues | Q46603171 | ||
Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation. | Q46686104 | ||
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins. | Q46808877 | ||
Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L. | Q46819743 | ||
Destabilizing role of cathepsin S in murine atherosclerotic plaques | Q46893001 | ||
Total and lipid-bound plasma sialic acid as diagnostic markers in colorectal cancer patients: correlation with cathepsin B expression in progression to Dukes stage. | Q46984342 | ||
Selective cysteine protease inhibition contributes to blood-feeding success of the tick Ixodes scapularis. | Q47840644 | ||
Autocatalytic processing of recombinant human procathepsin B is a bimolecular process | Q47851086 | ||
Rat procathepsin B. Proteolytic processing to the mature form in vitro. | Q47856856 | ||
Cathepsin B and cathepsin D expression in the progression of colorectal adenoma to carcinoma | Q47907185 | ||
Modulation of hypotensive effects of kinins by cathepsin K. | Q51092421 | ||
Major increase in endopeptidase activity of human cathepsin B upon removal of occluding loop contacts. | Q52528116 | ||
Acidic pH as a physiological regulator of human cathepsin L activity. | Q52534368 | ||
Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells. | Q53257403 | ||
Thyroglobulin type-1 domains in equistatin inhibit both papain-like cysteine proteinases and cathepsin D. | Q53744558 | ||
Modification of S1 subsite specificity in the cysteine protease cathepsin B. | Q54186211 | ||
Maturation of human procathepsin B. Proenzyme activation and proteolytic processing of the precursor to the mature proteinase, in vitro, are primarily unimolecular processes. | Q54760063 | ||
Neuronal ceroid lipofuscinoses | Q56566989 | ||
Serum cysteine proteases and their inhibitors in rheumatoid arthritis: relation to disease activity and radiographic progression | Q56974060 | ||
Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification | Q56999742 | ||
pH-induced conformational transitions of the propeptide of human cathepsin L. A role for a molten globule state in zymogen activation | Q57220930 | ||
Conformational Variability of Chicken Cystatin | Q57902438 | ||
Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA) | Q59287810 | ||
Lysosomal Cathepsins B and L and Stef in A Blood Levels in Patients with Hepatocellular Carcinoma and/or Liver Cirrhosis: Potential Clinical Implications | Q60245921 | ||
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment | Q63965514 | ||
Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes | Q64038856 | ||
Biosynthesis of leupeptin | Q67276489 | ||
Cathepsins B, H and L in human breast carcinoma | Q67848008 | ||
Potent slow-binding inhibition of cathepsin B by its propeptide | Q67974285 | ||
Human cathepsin B and cysteine proteinase inhibitors (CPIs) in inflammatory and metabolic joint diseases | Q68100706 | ||
Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion. | Q36996823 | ||
Lung cysteine cathepsins: intruders or unorthodox contributors to the kallikrein-kinin system? | Q37038006 | ||
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones | Q37053834 | ||
Cystatins from filarial parasites: evolution, adaptation and function in the host-parasite relationship | Q37076723 | ||
Activity-based protein profiling: from enzyme chemistry to proteomic chemistry | Q37119021 | ||
Cystatins: biochemical and structural properties, and medical relevance | Q37175525 | ||
Proteases: multifunctional enzymes in life and disease | Q37225060 | ||
Cathepsins: key modulators of cell death and inflammatory responses | Q37257916 | ||
Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells | Q37384330 | ||
Lysosomes as "suicide bags" in cell death: myth or reality? | Q37497722 | ||
Structure and functions of human kininogens | Q37506097 | ||
Diverse regulatory roles for lysosomal proteases in the immune response | Q37564269 | ||
Intracellular trafficking of lysosomal proteins and lysosomes | Q37664183 | ||
Development of nitrile-based peptidic inhibitors of cysteine cathepsins | Q37694669 | ||
Kininogens: More than cysteine protease inhibitors and kinin precursors | Q37719822 | ||
Cathepsins and cystatin C in atherosclerosis and obesity | Q37736846 | ||
Peptidase inhibitors in the MEROPS database | Q37739525 | ||
Cathepsins and their involvement in immune responses | Q37774592 | ||
Specialized roles for cysteine cathepsins in health and disease. | Q37797839 | ||
Mechanisms of amyloid fibril formation--focus on domain-swapping | Q37871074 | ||
Falcipains and other cysteine proteases of malaria parasites | Q37887586 | ||
Cystatins of parasitic organisms | Q37887599 | ||
The endosome-lysosome pathway and information generation in the immune system | Q37904214 | ||
The novel role of cathepsin L for neuropeptide production illustrated by research strategies in chemical biology with protease gene knockout and expression | Q37909147 | ||
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions | Q38298816 | ||
Engineering the S2 subsite specificity of human cathepsin S to a cathepsin L- and cathepsin B-like specificity | Q38301566 | ||
Characterization of cathepsin B specificity by site-directed mutagenesis. Importance of Glu245 in the S2-P2 specificity for arginine and its role in transition state stabilization. | Q38322542 | ||
Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion | Q39571113 | ||
Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide. | Q40002125 | ||
Selective activity-based probes for cysteine cathepsins | Q40049363 | ||
Antiinflammatory and immunosuppressive activity of sialostatin L, a salivary cystatin from the tick Ixodes scapularis. | Q40268385 | ||
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells | Q40341738 | ||
Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C). | Q40545373 | ||
Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function | Q27748903 | ||
The crystal structure of human procathepsin K | Q27766712 | ||
On the size of the active site in proteases. I. Papain | Q27860826 | ||
Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization | Q28137688 | ||
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis | Q28139155 | ||
Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis | Q28145435 | ||
Cystatins | Q28180897 | ||
Human and mouse proteases: a comparative genomic approach | Q28184208 | ||
Pycnodysostosis: role and regulation of cathepsin K in osteoclast function and human disease | Q28215150 | ||
Irreversible inhibitors of serine, cysteine, and threonine proteases | Q28217093 | ||
The crystal structure of human cathepsin L complexed with E-64 | Q28237390 | ||
Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems | Q28238035 | ||
Structure of papain | Q28255054 | ||
Autocatalytic processing of recombinant human procathepsin L. Contribution of both intermolecular and unimolecular events in the processing of procathepsin L in vitro | Q28262233 | ||
Sorting of non-glycosylated human procathepsin S in mammalian cells | Q28266262 | ||
Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis | Q28268059 | ||
Inactivation of human cystatin C and kininogen by human cathepsin D | Q28272426 | ||
The cystatins: Protein inhibitors of cysteine proteinases | Q28283958 | ||
High-molecular-weight kininogen binds two molecules of cysteine proteinases with different rate constants | Q28284858 | ||
Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review) | Q28285195 | ||
Molecular cloning and sequence analysis of human preprocathepsin C | Q28295805 | ||
Evolution of proteins of the cystatin superfamily | Q28298204 | ||
The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B | Q28359859 | ||
Exoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytes | Q28473458 | ||
Mouse stefins A1 and A2 (Stfa1 and Stfa2) differentiate between papain-like endo- and exopeptidases | Q28512369 | ||
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation | Q28590081 | ||
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor | Q28592058 | ||
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus | Q28613227 | ||
Friends or foes - bipolar effects of the tumour stroma in cancer | Q29619348 | ||
Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins. | Q30321506 | ||
Murine cathepsin F deficiency causes neuronal lipofuscinosis and late-onset neurological disease | Q30477117 | ||
Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts | Q30491065 | ||
Imaging proteolysis by living human glioma cells | Q30703032 | ||
Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes | Q30888032 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 68-88 | |
P577 | publication date | 2012-01-01 | |
P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
P1476 | title | Cysteine cathepsins: from structure, function and regulation to new frontiers | |
P478 | volume | 1824 |
Q37010428 | 58-F, a flavanone from Ophiopogon japonicus, prevents hepatocyte death by decreasing lysosomal membrane permeability |
Q33906314 | A 24-48 h fed Amblyomma americanum tick saliva immuno-proteome. |
Q92540903 | A Digital Pathology-Based Shotgun-Proteomics Approach to Biomarker Discovery in Colorectal Cancer |
Q89634052 | A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L |
Q47432033 | A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation |
Q48130527 | A model species for agricultural pest genomics: the genome of the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae). |
Q47096973 | A novel type I cystatin of parasite origin with atypical legumain-binding domain. |
Q34509595 | A role for stefin B (cystatin B) in inflammation and endotoxemia |
Q53410517 | A secretomics analysis reveals major differences in the macrophage responses towards different types of carbon nanotubes. |
Q49790068 | Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis |
Q52934515 | Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors. |
Q34534132 | Adenosine A2A receptor deficiency up-regulates cystatin F expression in white matter lesions induced by chronic cerebral hypoperfusion |
Q58588312 | Advanced glycation end products-related modulation of cathepsin L and NF-κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα |
Q55474273 | Affinity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L. |
Q37683503 | Alu-Derived Alternative Splicing Events Specific to Macaca Lineages in CTSF Gene |
Q36413078 | An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancer |
Q103001790 | An atypical and functionally diverse family of Kunitz-type cysteine/serine proteinase inhibitors secreted by the helminth parasite Fasciola hepatica |
Q38819292 | Analysis of the effect of a novel therapeutic for type 2 diabetes on the proteome of a muscle cell line. |
Q38964767 | Anti-cancer effects of novel doxorubicin prodrug PDOX in MCF-7 breast cancer cells |
Q52897133 | Antibody-conjugated drug assay for protease-cleavable antibody-drug conjugates. |
Q90381414 | Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction |
Q46414905 | Applicability of in vitro-in vivo translation of cathepsin K inhibition from animal species to human with the use of free-drug hypothesis |
Q88517025 | Association Between Cystatin C and 20-Year Cumulative Incidence of Hearing Impairment in the Epidemiology of Hearing Loss Study |
Q92258134 | Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome |
Q58756554 | Association of Epithelial Mesenchymal Transition with prostate and breast health disparities |
Q90332891 | Astrocyte-microglial association and matrix composition are common events in the natural history of primary familial brain calcification |
Q46828081 | Autophagy, Inflammation, and Immune Dysfunction in the Pathogenesis of Pancreatitis. |
Q52317562 | BEST1 protein stability and degradation pathways differ between autosomal dominant Best disease and autosomal recessive bestrophinopathy accounting for the distinct retinal phenotypes. |
Q37171011 | Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection |
Q91681407 | Biguanide is a modifiable pharmacophore for recruitment of endogenous Zn2+ to inhibit cysteinyl cathepsins: review and implications |
Q28546408 | Biochemical, transcriptomic and proteomic analyses of digestion in the scorpion Tityus serrulatus: insights into function and evolution of digestion in an ancient arthropod |
Q90324514 | Brown marmorated stink bug, Halyomorpha halys (Stål), genome: putative underpinnings of polyphagy, insecticide resistance potential and biology of a top worldwide pest |
Q33651196 | Caspase-1 participates in apoptosis of salivary glands in Rhipicephalus haemaphysaloides |
Q57046763 | Catch and Release Photosensitizers: Combining Dual Action Ruthenium Complexes with Protease Inactivation for Targeting Invasive Cancers |
Q28274479 | Cathepsin B Expression and the Correlation with Clinical Aspects of Oral Squamous Cell Carcinoma |
Q93200359 | Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction |
Q39044784 | Cathepsin B and L inhibitors: a patent review (2010 - present). |
Q26782938 | Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate |
Q38200056 | Cathepsin B: multiple roles in cancer |
Q55220507 | Cathepsin K associates with lymph node metastasis and poor prognosis in oral squamous cell carcinoma. |
Q35941710 | Cathepsin K induces platelet dysfunction and affects cell signaling in breast cancer - molecularly distinct behavior of cathepsin K in breast cancer |
Q41458755 | Cathepsin K knockout protects against cardiac dysfunction in diabetic mice |
Q36157546 | Cathepsin L Helps to Defend Mice from Infection with Influenza A. |
Q90212359 | Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation |
Q37297985 | Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis. |
Q90355647 | Cathepsin L secretion by host and neoplastic cells potentiates invasion |
Q35669806 | Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage |
Q37065664 | Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain. |
Q92592414 | Cathepsin S as a target in gastric cancer |
Q53832191 | Cathepsin S is associated with degradation of collagen I in abdominal aortic aneurysm. |
Q33589216 | Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization |
Q38949120 | Cathepsin-B induced controlled release from peptide-capped mesoporous silica nanoparticles. |
Q47849287 | Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation |
Q39237735 | Cathepsins in digestive cancers |
Q43244085 | Cathepsins in heart disease-chewing on the heartache? |
Q56535621 | Cathepsins: Proteases that are vital for survival but can also be fatal |
Q27704273 | Caught in the act: the crystal structure of cleaved cathepsin L bound to the active site of Cathepsin L |
Q36266181 | Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells |
Q34443252 | Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1. |
Q28079032 | Cellular proteostasis: degradation of misfolded proteins by lysosomes |
Q35603791 | Characterisation and expression analysis of cathepsins and ubiquitin-proteasome genes in gilthead sea bream (Sparus aurata) skeletal muscle |
Q96301222 | Characterization of a Trichinella spiralis cathepsin X and its promotion for the larval invasion of mouse intestinal epithelial cells |
Q91831377 | Characterization of proteolysis in muscle tissues of sea cucumber Stichopus japonicus |
Q47867122 | Chemical introduction of the green fluorescence: imaging of cysteine cathepsins by an irreversibly locked GFP fluorophore |
Q41116581 | Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats. |
Q36480910 | Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer |
Q38644377 | Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases |
Q47228764 | Computational predictions of cysteine cathepsin-mediated fibrinogen proteolysis |
Q38871517 | Conformational changes required for reovirus cell entry are sensitive to pH. |
Q47926090 | Copper(ii)-benzimidazole complexes as efficient fluorescent probes for l-cysteine in water |
Q91995280 | Covalent Inhibition in Drug Discovery |
Q61444815 | Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L |
Q36746295 | Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity |
Q46797867 | Cystatin C deficiency suppresses tumor growth in a breast cancer model through decreased proliferation of tumor cells. |
Q38341202 | Cystatin C is a disease-associated protein subject to multiple regulation |
Q38835714 | Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression. |
Q92853428 | Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer |
Q35592746 | Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines |
Q64069431 | Cysteine Cathepsins and their Extracellular Roles: Shaping the Microenvironment |
Q90290679 | Cysteine Cathepsins in Tumor-Associated Immune Cells |
Q26747530 | Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets |
Q41852264 | Cysteine cathepsin activity regulation by glycosaminoglycans |
Q38182521 | Cysteine cathepsins and their potential in clinical therapy and biomarker discovery |
Q35910069 | Cysteine cathepsins are essential in lysosomal degradation of α-synuclein. |
Q38292676 | Cysteine cathepsins as regulators of the cytotoxicity of NK and T cells. |
Q26827307 | Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes |
Q34333230 | Cysteine peptidases and their inhibitors in Tetranychus urticae: a comparative genomic approach. |
Q26771736 | Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors |
Q38756684 | Cysteine proteases in atherosclerosis |
Q58716061 | Cysteine proteases in protozoan parasites |
Q91690107 | Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions |
Q38870241 | Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62. |
Q26700100 | Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability |
Q38169006 | Dentin biomodification: strategies, renewable resources and clinical applications |
Q53372260 | Design, characterization and cellular uptake studies of fluorescence-labeled prototypic cathepsin inhibitors. |
Q55467684 | Designer Oncolytic Adenovirus: Coming of Age. |
Q41143858 | Detection of bioorthogonal groups by correlative light and electron microscopy allows imaging of degraded bacteria in phagocytes |
Q36469004 | Development of α-helical calpain probes by mimicking a natural protein-protein interaction |
Q36087869 | Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target. |
Q52685987 | Differential Protein Profiling of Cerebrospinal Fluid in Piglets with Severe Meningoencephalitis Caused by Streptococcus suis Type 2 Compared to Controls. |
Q36577139 | Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway |
Q89571641 | Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS |
Q26825638 | Disruptions of Host Immunity and Inflammation by Giardia Duodenalis: Potential Consequences for Co-Infections in the Gastro-Intestinal Tract |
Q34271356 | Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. |
Q35092804 | Drosophila melanogaster cellular repressor of E1A-stimulated genes is a lysosomal protein essential for fly development |
Q43874096 | Dynamic identification of H2 epitopes from Leishmania (Leishmania) amazonensis cysteine proteinase B with potential immune activity during murine infection. |
Q47664632 | Dysfunction of Membrane Trafficking Leads to Ischemia-Reperfusion Injury After Transient Cerebral Ischemia |
Q64991702 | Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process. |
Q64930732 | Effect of Non-Vital Bleaching on the Durability of Resin⁻Dentin Bond with an Ethanol-Based Etch-And-Rinse Adhesive. |
Q28069869 | Effects of Glycosylation on the Enzymatic Activity and Mechanisms of Proteases |
Q38647522 | Effects of Vacuolar H(+)-ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA-MB231 Breast Cancer Cells. |
Q38714350 | Effects of lysosomal biotherapeutic recombinant protein expression on cell stress and protease and general host cell protein release in Chinese hamster ovary cells. |
Q36682721 | Effects of open versus laparoscopic nephrectomy techniques on oxidative stress markers in patients with renal cell carcinoma |
Q59329101 | Efficient silica synthesis from tetra(glycerol)orthosilicate with cathepsin- and silicatein-like proteins |
Q34211633 | Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella |
Q90107218 | Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's disease |
Q58705798 | Endocrine Crosstalk Between Skeletal Muscle and the Brain |
Q41170128 | Endocytosis and Enamel Formation |
Q39385660 | Engineered nanomaterial-induced lysosomal membrane permeabilization and anti-cathepsin agents |
Q36264141 | Enhanced transcriptomic responses in the Pacific salmon louse Lepeophtheirus salmonis oncorhynchi to the non-native Atlantic Salmon Salmo salar suggests increased parasite fitness |
Q50216109 | Enzymatic modification by point mutation and functional analysis of an omega-6 fatty acid desaturase from Arctic Chlamydomonas sp. |
Q26741532 | Enzymes in Fish and Seafood Processing |
Q43185053 | EpCAM proteolysis: new fragments with distinct functions? |
Q35914308 | Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism |
Q35891325 | Evolutionary History of Cathepsin L (L-like) Family Genes in Vertebrates |
Q36505367 | Expression patterns of cysteine peptidase genes across the Tribolium castaneum life cycle provide clues to biological function |
Q36502689 | Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients |
Q36385028 | Expression, purification, and characterization of human cystatin C monomers and oligomers |
Q50791577 | FPPS: Fast Profiling of Protease Specificity. |
Q91026500 | Fasciola gigantica: Comparison of the tegumental ultrastructure in newly excysted metacercariae and in vitro penetrated juvenile flukes indicates intracellular sources of molecules with vaccinal and immunomodulatory potential |
Q38417182 | Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S. |
Q91709813 | Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples |
Q98721032 | Food proteins are a potential resource for mining cathepsin L inhibitory drugs to combat SARS-CoV-2 |
Q41732169 | Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage |
Q35108627 | Functional analysis of C1 family cysteine peptidases in the larval gut of Тenebrio molitor and Tribolium castaneum |
Q38465020 | Gene network and canonical pathway analysis in canine myxomatous mitral valve disease: a microarray study |
Q49552599 | Giardia Secretome Highlights Secreted Tenascins as a Key Component of Pathogenesis |
Q35762858 | Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase |
Q42735511 | Giardia duodenalis cathepsin B proteases degrade intestinal epithelial interleukin-8 and attenuate interleukin-8-induced neutrophil chemotaxis |
Q64982206 | Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation. |
Q40743173 | HIV Protease Inhibitor-Induced Cathepsin Modulation Alters Antigen Processing and Cross-Presentation |
Q41121841 | High lumenal chloride in the lysosome is critical for lysosome function |
Q47100235 | Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells. |
Q51763123 | Histone tail cleavage as a novel epigenetic regulatory mechanism for gene expression. |
Q89259957 | Human cathepsins K, L, and S: Related proteases, but unique fibrinolytic activity |
Q44870181 | Human cystatin C: a new biomarker of idiopathic pulmonary fibrosis? |
Q37581801 | Identification and function of proteolysis regulators in seminal fluid |
Q40747704 | Identification, mRNA expression profiling and activity characterization of cathepsin L from red drum (Sciaenops ocellatus). |
Q46828103 | In Search of a Converging Cellular Mechanism in Nanotoxicology and Nanomedicine in the Treatment of Cancer |
Q64087585 | In Silico Analysis of Homologous Heterodimers of Cruzipain-Chagasin from Structural Models Built by Homology |
Q47642547 | Inactivation of NSF ATPase Leads to Cathepsin B Release After Transient Cerebral Ischemia |
Q89675940 | Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression |
Q57025651 | Increasing time on target: utilization of inhibitors of cysteine cathepsins to enhance the tumor retention of receptor-targeted agents |
Q52374264 | Indispensable Role of Proteases in Plant Innate Immunity. |
Q42619504 | Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases |
Q38943054 | Insights from molecular modeling into the selective inhibition of cathepsin S by its inhibitor |
Q50882222 | Insights into the mechanism of cystatin C oligomer and amyloid formation and its interaction with β-amyloid. |
Q36806048 | Insufficient Generation of Mycobactericidal Mediators and Inadequate Level of Phagosomal Maturation Are Related with Susceptibility to Virulent Mycobacterium tuberculosis Infection in Mouse Macrophages |
Q51747909 | Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. |
Q61959522 | Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone |
Q33812663 | Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines. |
Q42150501 | Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice |
Q61805484 | Isolation and characterization of a tandem-repeated cysteine protease from the symbiotic dinoflagellate Symbiodinium sp. KB8 |
Q47384752 | Isolation of Salmonella typhimurium-containing Phagosomes from Macrophages. |
Q38557771 | Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions |
Q92030391 | KMT2A histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation |
Q35758680 | Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells |
Q38009194 | Killing a cancer: what are the alternatives? |
Q38654407 | LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes |
Q34262192 | Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity |
Q46572905 | Ligation of FcγR Alters Phagosomal Processing of Protein via Augmentation of NADPH Oxidase Activity |
Q58920565 | Lithium chloride enhances cathepsin H expression and BMP-4 degradation in C3H10T1/2 cells |
Q52864120 | Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe. |
Q52725925 | Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals. |
Q91784087 | Lysosomal Proteases Are a Determinant of Coronavirus Tropism |
Q26749121 | Lysosomal cathepsins and their regulation in aging and neurodegeneration |
Q34264949 | Lysosomal pathways to cell death and their therapeutic applications. |
Q35116175 | Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells. |
Q36357685 | Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis |
Q93064841 | Lysosomes as a therapeutic target |
Q64914067 | MAV_4644 Interaction with the Host Cathepsin Z Protects Mycobacterium avium subsp. hominissuis from Rapid Macrophage Killing. |
Q27690658 | Macrocyclic protease inhibitors with reduced peptide character |
Q61814442 | Magnesium Is a Key Regulator of the Balance between Osteoclast and Osteoblast Differentiation in the Presence of Vitamin D₃ |
Q39003421 | Mammalian orthoreovirus T3D infects U-118 MG cell spheroids independent of junction adhesion molecule-A. |
Q36593560 | Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy |
Q34475790 | Mast cell proteases as pharmacological targets |
Q50215750 | Measuring Phagosomal pH by Fluorescence Microscopy |
Q38991409 | Mechanisms of buffer therapy resistance |
Q47827985 | Meta-analysis of transcriptomic changes in optic nerve injury and neurodegenerative models reveals a fundamental response to injury throughout the central nervous system. |
Q38799069 | Microbial inhibitors of cysteine proteases. |
Q88670186 | Modulation of Receptor Protein Tyrosine Phosphatase Sigma Increases Chondroitin Sulfate Proteoglycan Degradation through Cathepsin B Secretion to Enhance Axon Outgrowth |
Q41862863 | Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT. |
Q39452252 | Molecular and immunological characterization of cathepsin L-like cysteine protease of Paragonimus pseudoheterotremus |
Q35096243 | Molecular characterization and serological reactivity of a vacuolar ATP synthase subunit ε-like protein from Clonorchis sinensis |
Q37526196 | Molecular characterization of firefly nuptial gifts: a multi-omics approach sheds light on postcopulatory sexual selection |
Q47843948 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. |
Q42428279 | Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation |
Q111271454 | Multiple sites on SARS-CoV-2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V |
Q28552228 | Mutation in the Pro-Peptide Region of a Cysteine Protease Leads to Altered Activity and Specificity-A Structural and Biochemical Approach |
Q50898615 | Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure. |
Q90356650 | Myocardial cathepsin D is downregulated in sudden cardiac death |
Q46200816 | Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion |
Q41824919 | NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation |
Q36884629 | Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases |
Q37691517 | Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer |
Q28260087 | Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity |
Q41455465 | Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin |
Q50453909 | Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors. |
Q30389896 | Novel proteases from the genome of the carnivorous plant Drosera capensis: Structural prediction and comparative analysis |
Q52591302 | Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability. |
Q26866319 | Optimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsins |
Q48014081 | PACMANS: A bioinformatically informed algorithm to predict, design, and disrupt protease-on-protease hydrolysis. |
Q40470485 | PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment. |
Q92828409 | Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization |
Q37238697 | Pathogenesis of mitral valve disease in mucopolysaccharidosis VII dogs. |
Q34635528 | Pharmacokinetics and pharmacodynamics of the cathepsin S inhibitor, LY3000328, in healthy subjects. |
Q98158951 | Photoaging Skin Therapy with PRP and ADSC: A Comparative Study |
Q90213483 | Plasma proteomic signature of the risk of developing mobility disability: A 9-year follow-up |
Q38203114 | Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings |
Q27677225 | Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases |
Q95843513 | Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy? |
Q111348329 | Potential roles of two Cathepsin genes, DcCath-L and DcCath-O in the innate immune response of Diaphorina citri |
Q90310495 | Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis |
Q92694063 | Prolines Affect the Nucleation Phase of Amyloid Fibrillation Reaction; Mutational Analysis of Human Stefin B |
Q37022937 | Propeptides of eukaryotic proteases encode histidines to exploit organelle pH for regulation. |
Q33734766 | Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction. |
Q48364393 | Protease cleavage site fingerprinting by label-free in-gel degradomics reveals pH-dependent specificity switch of legumain. |
Q38663181 | Protease signaling in animal and plant-regulated cell death |
Q48691301 | Protease-activated nanomaterials for targeted cancer theranostics |
Q33795055 | Proteases Revisited: Roles and Therapeutic Implications in Fibrosis |
Q38268345 | Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges |
Q37629015 | Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer |
Q36294814 | Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization |
Q47271370 | Proteolytic systems' expression during myogenesis and transcriptional regulation by amino acids in gilthead sea bream cultured muscle cells. |
Q38409707 | Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells. |
Q35072858 | Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2. |
Q55131844 | Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes. |
Q39259454 | RNA interference and dietary inhibitors induce a similar compensation response in Tribolium castaneum larvae |
Q41181668 | Rational Design of Recombinant Papain-Like Cysteine Protease: Optimal Domain Structure and Expression Conditions for Wheat-Derived Enzyme Triticain-α. |
Q26828960 | Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination |
Q93022937 | Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders |
Q34905953 | Recognition of higher order patterns in proteins: immunologic kernels |
Q64389267 | Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation |
Q33718504 | Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C. |
Q90363169 | Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants |
Q38103557 | Relationship between the proteasomal system and autophagy |
Q64248857 | Resin-Dentin Bonding Interface: Mechanisms of Degradation and Strategies for Stabilization of the Hybrid Layer |
Q89658859 | Revisiting the Roles of Pro-Metastatic EpCAM in Cancer |
Q37215806 | Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages |
Q27026498 | Role of integrins in the periodontal ligament: organizers and facilitators |
Q57584188 | Rotavirus Attachment, Internalization, and Vesicular Traffic |
Q37713871 | Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell |
Q28276622 | Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function |
Q41434747 | STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation |
Q40990114 | Salivary Tick Cystatin OmC2 Targets Lysosomal Cathepsins S and C in Human Dendritic Cells |
Q41334657 | Salvianolic acid B protects hepatocytes from H2O2 injury by stabilizing the lysosomal membrane |
Q55023666 | Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes. |
Q93075496 | Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model |
Q28829764 | Sequence comparison, molecular modeling, and network analysis predict structural diversity in cysteine proteases from the Cape sundew, Drosera capensis |
Q64097586 | Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis |
Q38971054 | Serpin1 and WSCP differentially regulate the activity of the cysteine protease RD21 during plant development in Arabidopsis thaliana |
Q99635486 | Serum cystatin C is closely associated with euthyroid Hashimoto's thyroiditis in adult female Chinese patients |
Q92609903 | Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation |
Q96230684 | Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection |
Q36743865 | Split top: a maternal cathepsin B that regulates dorsoventral patterning and morphogenesis |
Q91879301 | Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase |
Q48533476 | Stat3 mediated alterations in lysosomal membrane protein composition |
Q42275957 | Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model. |
Q36169439 | Structural Dynamics Investigation of Human Family 1 & 2 Cystatin-Cathepsin L1 Interaction: A Comparison of Binding Modes |
Q37065874 | Structural and Functional Characterization of the Major Allergen Amb a 11 from Short Ragweed Pollen |
Q89392305 | Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states |
Q34277879 | Structural basis for specificity of propeptide-enzyme interaction in barley C1A cysteine peptidases |
Q27682067 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function |
Q99587434 | Structure of the Plasmodium falciparum PfSERA5 pseudo-zymogen |
Q41856866 | Studies of inhibitory mechanisms of propeptide-like cysteine protease inhibitors |
Q39137404 | Synthesis and radiopharmacological characterisation of a fluorine-18-labelled azadipeptide nitrile as a potential PET tracer for in vivo imaging of cysteine cathepsins |
Q94541646 | TMEM9-v-ATPase Activates Wnt/β-Catenin Signaling via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis |
Q92373377 | TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin |
Q52598834 | Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers. |
Q64234280 | The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K |
Q64248056 | The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells |
Q41619854 | The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability |
Q30936124 | The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution. |
Q89966156 | The Functional Effects of Key Driver KRAS Mutations on Gene Expression in Lung Cancer |
Q38357779 | The HIV protease inhibitor saquinavir inhibits HMGB1 driven inflammation by targeting the interaction of cathepsin V with TLR4/MyD88 |
Q97557237 | The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management |
Q47351855 | The Intra-Cellular Localization of the Vanillin Biosynthetic Machinery in Pods of Vanilla planifolia |
Q60944020 | The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation |
Q99413952 | The Potential Role of Cathepsin K in Non-Small Cell Lung Cancer |
Q92150617 | The Role of Cysteine Cathepsins in Cancer Progression and Drug Resistance |
Q26799771 | The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung |
Q29248184 | The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3 |
Q96954446 | The expression of Cathepsin L in oral lichen planus |
Q37568511 | The function of cathepsins B, D, and X in atherosclerosis |
Q38072995 | The role of cysteine proteinases and their inhibitors in the host-pathogen cross talk |
Q27683442 | The structure of a thermostable mutant of pro-papain reveals its activation mechanism |
Q39245158 | The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1. |
Q27683866 | The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium |
Q45760136 | Theoretical insight into the mechanism for the inhibition of the cysteine protease cathepsin B by 1,2,4-thiadiazole derivatives |
Q37212428 | Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins |
Q36534915 | Tooth bleaching increases dentinal protease activity. |
Q36040040 | Transcriptome Analysis of the Sydney Rock Oyster, Saccostrea glomerata: Insights into Molluscan Immunity |
Q92669055 | Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal milieu |
Q89449453 | Transcriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon |
Q40611895 | Transgenic Expression of a Viral Cystatin Gene CpBV-CST1 in Tobacco Confers Insect Resistance |
Q46360939 | Tumor Necrosis Factor-α Induced Apoptosis in U937 Cells Promotes Cathepsin D-Independent Stefin B Degradation |
Q34761929 | Uncovering the cathepsin system in heart failure patients submitted to Left Ventricular Assist Device (LVAD) implantation. |
Q37998091 | Use of cysteine-reactive small molecules in drug discovery for trypanosomal disease |
Q89682842 | Utilizing Experimental Mouse Model to Identify Effectors of Hepatocellular Carcinoma Induced by HBx Antigen |
Q28656193 | Vanillin formation from ferulic acid in Vanilla planifolia is catalysed by a single enzyme |
Q30383716 | Vasohibins: new transglutaminase-like cysteine proteases possessing a non-canonical Cys-His-Ser catalytic triad |
Q39208117 | Yeast as a tool to explore cathepsin D function |
Q37691916 | c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer |
Q98513731 | p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy-lysosomal pathway and coordinate cell cycle and cell growth |
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