| scholarly article | Q13442814 |
| P50 | author | Carolyn Bertozzi | Q7442 |
| Ilse Dingjan | Q57665694 | ||
| Maksim V Baranov | Q88031339 | ||
| Martin Ter Beest | Q114406732 | ||
| Geert van den Bogaart | Q38803239 | ||
| Frans Bianchi | Q42395529 | ||
| P2093 | author name string | Ulf Diederichsen | |
| Martijn Verdoes | |||
| Samantha G L Keyser | |||
| Elke M Muntjewerff | |||
| Anastasiya Schirmacher | |||
| Melissa A C van Aart | |||
| Sjors Maassen | |||
| P2860 | cites work | Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways | Q46424023 |
| Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation. | Q47740081 | ||
| pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels. | Q48093319 | ||
| Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma | Q50192754 | ||
| Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes | Q50335815 | ||
| Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages. | Q50435732 | ||
| The phagosome and redox control of antigen processing | Q51734853 | ||
| Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor | Q51978359 | ||
| Inhibition of c-Rel DNA binding is critical for the anti-inflammatory effects of novel PIKfyve inhibitor | Q53140964 | ||
| Bioorthogonal deprotection on the dendritic cell surface for chemical control of antigen cross-presentation | Q53579489 | ||
| Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes | Q55131844 | ||
| PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox | Q57057849 | ||
| Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements | Q57228054 | ||
| NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells | Q58007061 | ||
| Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells | Q58323390 | ||
| Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes | Q59098594 | ||
| Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments | Q71843540 | ||
| Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice | Q74595052 | ||
| One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules | Q77994488 | ||
| A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease | Q79802717 | ||
| A polymorphic pocket at the P10 position contributes to peptide binding specificity in class II MHC proteins | Q80872298 | ||
| Brief Report: A phase IIa, randomized, double‐blind, placebo‐controlled trial of apilimod mesylate, an interleukin‐12/interleukin‐23 inhibitor, in patients with rheumatoid arthritis | Q82964583 | ||
| Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms | Q84776563 | ||
| Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex | Q24307982 | ||
| Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading | Q24328923 | ||
| Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells | Q24599234 | ||
| Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636 | Q24615140 | ||
| Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella | Q24620024 | ||
| A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding | Q24645971 | ||
| A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells | Q26747063 | ||
| Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets | Q26747530 | ||
| Regulation of Th2 Cell Immunity by Dendritic Cells | Q26764869 | ||
| Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance | Q26823539 | ||
| Cysteine cathepsins: from structure, function and regulation to new frontiers | Q26860406 | ||
| Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide | Q27731272 | ||
| Dendritic cells and the control of immunity | Q27860918 | ||
| Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization | Q28204986 | ||
| Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve | Q28210351 | ||
| PIKfyve: The road to PtdIns 5‐P and PtdIns 3,5‐P2 | Q28212011 | ||
| Activation and assembly of the NADPH oxidase: a structural perspective | Q28297425 | ||
| Apilimod Inhibits the Production of IL-12 and IL-23 and Reduces Dendritic Cell Infiltration in Psoriasis | Q28482161 | ||
| Cathepsin S required for normal MHC class II peptide loading and germinal center development | Q28611850 | ||
| PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling | Q28833590 | ||
| PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome | Q29543488 | ||
| Lifeact: a versatile marker to visualize F-actin | Q29547604 | ||
| The PX domains of p47phox and p40phox bind to lipid products of PI(3)K | Q30016925 | ||
| Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins. | Q30321506 | ||
| Redirecting soluble antigen for MHC class I cross-presentation during phagocytosis | Q30392181 | ||
| Phagosome maturation: going through the acid test | Q30435417 | ||
| PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils | Q30514916 | ||
| Comparative quantitative mass spectrometry analysis of MHC class II-associated peptides reveals a role of GILT in formation of self-peptide repertoire | Q33582318 | ||
| Pathways of antigen processing | Q33631854 | ||
| Cathepsins and compartmentalization in antigen presentation | Q33840535 | ||
| Proteolysis in MHC class II antigen presentation: who's in charge? | Q33885986 | ||
| Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance | Q33897693 | ||
| NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes | Q33935056 | ||
| Molecular imaging analysis of Rab GTPases in the regulation of phagocytosis and macropinocytosis | Q38623746 | ||
| PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment. | Q38746550 | ||
| Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency | Q38762724 | ||
| A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation. | Q38788245 | ||
| SWAP70 is a universal GEF-like adapter for tethering actin to phagosomes. | Q38794036 | ||
| B-cell non-Hodgkin lymphoma: Selective vulnerability to PIKFYVE inhibition | Q38871390 | ||
| Oxidized phagosomal NOX2 complex is replenished from lysosomes. | Q38959357 | ||
| PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages. | Q38973926 | ||
| PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. | Q38993815 | ||
| NADPH oxidase modifies patterns of MHC class II-restricted epitopic repertoires through redox control of antigen processing | Q39000471 | ||
| Stop or Go? Endosome Positioning in the Establishment of Compartment Architecture, Dynamics, and Function | Q39211884 | ||
| Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3‐phosphate dynamics | Q39258904 | ||
| Phosphatidylinositol 3-phosphate is generated in phagosomal membranes. | Q39584074 | ||
| The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase | Q40105885 | ||
| Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape. | Q40455870 | ||
| Toll receptor-mediated regulation of NADPH oxidase in human dendritic cells. | Q40501902 | ||
| The Optimization of Bioorthogonal Epitope Ligation within MHC-I Complexes | Q40553719 | ||
| Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. | Q40616484 | ||
| Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner | Q41164914 | ||
| Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells | Q41440525 | ||
| Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures | Q41450247 | ||
| Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes | Q41515448 | ||
| CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. | Q41538630 | ||
| Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice | Q42133744 | ||
| VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release | Q42378080 | ||
| PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation | Q42833229 | ||
| Activation of lysosomal function during dendritic cell maturation | Q44333919 | ||
| Control of Phagocytosis by Microbial Pathogens. | Q44612676 | ||
| Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease | Q45841458 | ||
| Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors | Q46097132 | ||
| Isolation and characterization of the intracellular MHC class II compartment. | Q34340778 | ||
| Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources | Q34561569 | ||
| Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM. | Q34665662 | ||
| Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. | Q34784632 | ||
| Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function | Q34959368 | ||
| Lysosomal cysteine proteases regulate antigen presentation | Q35140806 | ||
| Calcium: a fundamental regulator of intracellular membrane fusion? | Q35658408 | ||
| Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant | Q36230570 | ||
| Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012). | Q36257177 | ||
| Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes. | Q36274077 | ||
| Two-gene control of the expression of a murine Ia antigen | Q36341979 | ||
| Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles | Q36364770 | ||
| Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest | Q36377580 | ||
| APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex | Q36446860 | ||
| NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells. | Q37002001 | ||
| MHC class II molecules on the move for successful antigen presentation | Q37018661 | ||
| Improved quenched fluorescent probe for imaging of cysteine cathepsin activity | Q37304778 | ||
| Cathepsin S activity regulates antigen presentation and immunity | Q37382422 | ||
| Antimicrobial mechanisms of phagocytes and bacterial evasion strategies | Q37445493 | ||
| SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. | Q37492071 | ||
| YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes | Q37543490 | ||
| The signaling lipid PI(3,5)P₂ stabilizes V₁-V(o) sector interactions and activates the V-ATPase | Q37696871 | ||
| Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2. | Q37898748 | ||
| The cell biology of phagocytosis | Q37930659 | ||
| How nascent phagosomes mature to become phagolysosomes | Q38007730 | ||
| Cross-presentation by dendritic cells | Q38025870 | ||
| Reactive oxygen species production in the phagosome: impact on antigen presentation in dendritic cells | Q38029097 | ||
| CORVET and HOPS tethering complexes–coordinators of endosome and lysosome fusion | Q38104286 | ||
| MHC class II antigen presentation by dendritic cells regulated through endosomal sorting | Q38167996 | ||
| Phosphoinositides in phagocytosis and macropinocytosis | Q38252674 | ||
| PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3. | Q38308555 | ||
| The ins and outs of MHC class II-mediated antigen processing and presentation | Q38365560 | ||
| PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes | Q38600541 | ||
| Lipid peroxidation causes endosomal antigen release for cross-presentation | Q38608424 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 160-177 | |
| P577 | publication date | 2018-12-20 | |
| P1476 | title | The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation | |
| P478 | volume | 11 |
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