scholarly article | Q13442814 |
P2093 | author name string | P E Jensen | |
P2860 | cites work | Insulin degradation: mechanisms, products, and significance | Q28289497 |
Thioredoxin | Q29619691 | ||
Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. | Q34213308 | ||
A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis | Q36222502 | ||
Enhanced binding of peptide antigen to purified class II major histocompatibility glycoproteins at acidic pH. | Q36230523 | ||
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition | Q36344766 | ||
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing | Q36348935 | ||
Regulation of antigen presentation by acidic pH. | Q36351024 | ||
Flexibility of the T cell repertoire. Self tolerance causes a shift of T cell receptor gene usage in response to insulin | Q36351053 | ||
Photoaffinity labeling demonstrates binding between Ia molecules and nominal antigen on antigen-presenting cells | Q37392832 | ||
Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis | Q37557662 | ||
Antigen conformation determines processing requirements for T-cell activation | Q37576188 | ||
Specific binding of antigenic peptides to separate alpha and beta chains of class II molecules of the major histocompatibility complex | Q37666665 | ||
The basis for the immunoregulatory role of macrophages and other accessory cells | Q38174608 | ||
Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins | Q38274381 | ||
Immune response gene control of determinant selection. II. Genetic control of the murine T lymphocyte proliferative response to insulin | Q39548996 | ||
Antigen processing and the human T cell receptor repertoire for insulin | Q41254325 | ||
The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation | Q41279676 | ||
Processing without proteolytic cleavage is required for recognition of insulin by T cells | Q41711445 | ||
Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes | Q41715127 | ||
Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments | Q41724706 | ||
Development of T cell clones reactive to two defined restriction elements in conjunction with two defined epitopes of antigen | Q41934641 | ||
Protein synthesis in antigen processing. | Q41947029 | ||
Role of thiols, pH and cathepsin D in the lysosomal catabolism of serum albumin | Q42093504 | ||
Disulphide reduction in lysosomes. The role of cysteine | Q42200276 | ||
Establishment of B cell hybridomas with B cell surface antigens. | Q42799227 | ||
Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas. | Q42823565 | ||
Processing by accessory cells for presentation to murine T cells of apamin, a disulfide-bonded 18 amino acid peptide | Q43703469 | ||
Disulfide spacer between methotrexate and poly(D-lysine). A probe for exploring the reductive process in endocytosis | Q43882742 | ||
T cells from nonresponder mice. MHC restricted and unrestricted recognition of insulin | Q43993541 | ||
Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells. | Q44763280 | ||
Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line | Q44802945 | ||
Regions of allelic hypervariability in the murine Aα immune response gene | Q48397143 | ||
Murine I-A beta chain polymorphism: nucleotide sequences of three allelic I-A beta genes | Q48397403 | ||
Isolation and characterization of antigen-la complexes involved in T cell recognition | Q57000170 | ||
Binding of immunogenic peptides to Ia histocompatibility molecules | Q59070314 | ||
Immunology: The ins and outs of antigen processing and presentations | Q59073630 | ||
Evidence for lysosomal reduction of cystine residues | Q66938676 | ||
Immunogenicity of B chain in insulin responder and nonresponder mice | Q67669955 | ||
High-affinity binding of an influenza hemagglutinin-derived peptide to purified HLA-DR | Q68717435 | ||
Stable association of processed antigen with antigen-presenting cell membranes | Q69740308 | ||
Capacity of intact proteins to bind to MHC class II molecules | Q69741058 | ||
Studies on monoclonal antibodies to mouse MHC products | Q72642947 | ||
Epitope specificity and Ia restriction of T cell responses to insulin in a system of complementing Ir genes: analysis with primed lymph node T cells and a long-term cultured T cell line | Q72711826 | ||
Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation | Q72717995 | ||
Studies on the reaction of sulfite with proteins | Q78734313 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | preproinsulin | Q7240673 |
P304 | page(s) | 1121-1130 | |
P577 | publication date | 1991-11-01 | |
P1433 | published in | Journal of Experimental Medicine | Q3186912 |
P1476 | title | Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant | |
P478 | volume | 174 |
Q24674180 | Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes |
Q41444149 | Allele specificity of structural requirement for peptides bound to HLA-DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome |
Q52006255 | Amino acid residue substitution at T-cell determinant-flanking sites in beta-lactoglobulin modulates antigen presentation to T cells through subtle conformational change |
Q58323370 | Antigen Presentation--Losing Its Shine in the Absence of GILT |
Q36232748 | Antigen presentation: lysoyme, autoimmune diabetes, and Listeria--what do they have in common? |
Q34129315 | Antigen processing in the endocytic compartment |
Q28344126 | Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis |
Q40901299 | Cellular and molecular aspects of antigen processing and the function of class II MHC molecules |
Q46512462 | Characterisation of the antibody response to a totally synthetic immunocontraceptive peptide vaccine based on LHRH. |
Q40202675 | Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo |
Q28586564 | Defective Antigen Processing in GILT-Free Mice |
Q41147813 | Defective antigen processing correlates with a low level of intracellular glutathione |
Q35884189 | Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection |
Q56395856 | Determination of a Predictive Cleavage Motif for Eluted Major Histocompatibility Complex Class II Ligands |
Q28343874 | Differing processing requirements of four recombinant antigens containing a single defined T-cell epitope for presentation by major histocompatibility complex class II |
Q37867108 | Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase |
Q43926217 | Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response |
Q77745561 | Disulfide reduction in major histocompatibility complex class II-restricted antigen processing by interferon-gamma-inducible lysosomal thiol reductase |
Q34579769 | Diversity in MHC class II antigen presentation |
Q35058921 | Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities |
Q77965788 | Drug-induced inhibition of insulin recognition by T-cells: the antirheumatic drug aurothiomalate inhibits MHC binding of insulin peptide |
Q40165086 | Endogenous and exogenous pathways maintain the reductive capacity of the phagosome |
Q39319598 | Evaluating the intrinsic cysteine redox-dependent states of the A-chain of human insulin using NMR spectroscopy, quantum chemical calculations, and mass spectrometry |
Q58199442 | Exploring the mechanisms of antigen processing by cell fractionation |
Q40729404 | Factors governing the binding and recognition of foreign and self-peptides by MHC class II. |
Q33650907 | Folding of matrix metalloproteinase-2 prevents endogenous generation of MHC class-I restricted epitope |
Q37453613 | GILT: Shaping the MHC Class II-Restricted Peptidome and CD4(+) T Cell-Mediated Immunity |
Q28138259 | Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action |
Q54082354 | Importance of thioredoxin in the proteolysis of an immunoglobulin G as antigen by lysosomal Cys-proteases |
Q33264116 | Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing |
Q45097915 | Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide |
Q42800203 | Lysosomal handling of cystine residues: stoichiometry of cysteine involvement |
Q81312026 | Major histocompatibility class II molecules prevent destructive processing of exogenous peptides at the cell surface of macrophages for presentation to CD4 T cells |
Q41389653 | Modulation of antigen processing and presentation by covalently linked complement C3b fragment. |
Q57372149 | Molecular Interaction and Enzymatic Activity of Macrophage Migration Inhibitory Factor with Immunorelevant Peptides |
Q35206214 | Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic epithelial cells |
Q77586745 | Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells |
Q34162875 | Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates |
Q33683408 | Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses |
Q28611993 | Presentation of antigens by MHC class II molecules: getting the most out of them |
Q28612038 | Proteolysis and antigen presentation by MHC class II molecules |
Q28265298 | Qa-1, a nonclassical class I histocompatibility molecule with roles in innate and adaptive immunity |
Q38160013 | Redox-sensitive probes for the measurement of redox chemistries within phagosomes of macrophages and dendritic cells |
Q37904710 | T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives |
Q24655467 | T-cell responses to the trypanosome variant surface glycoprotein are not limited to hypervariable subregions |
Q60944020 | The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation |
Q72815534 | The efficient bovine insulin presentation capacity of bone marrow-derived macrophages activated by granulocyte-macrophage colony-stimulating factor correlates with a high level of intracellular reducing thiols |
Q28591372 | The in vivo antibody response against exogenous antigens is not influenced by the mouse Bcg (Nramp1) gene |
Q36403698 | The insulin A-chain epitope recognized by human T cells is posttranslationally modified |
Q71011967 | Tolerance is overcome in beef insulin-transgenic mice by activation of low-affinity autoreactive T cells |
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