Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo

scientific article published on 29 November 2006

Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00775-006-0192-8
P698PubMed publication ID17136409
P5875ResearchGate publication ID226546573

P50authorMarcin KruszewskiQ52882850
Barbara SochanowiczQ58656865
Hanna LewandowskaQ60585594
Jarosław SadłoQ60585597
P2093author name stringSylwia Meczyńska
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Glutathione transferase superfamily behaves like storage proteins for dinitrosyl-diglutathionyl-iron complex in heterogeneous systemsQ24309594
Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporterQ27937730
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Induction of iron regulatory protein 1 RNA-binding activity by nitric oxide is associated with a concomitant increase in the labile iron pool: implications for DNA damageQ28513474
Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexesQ28575527
Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosisQ28591791
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The physiological activity and in vivo distribution of dinitrosyl dithiolato iron complexQ33956908
Commentary. Lysosomotropic agentsQ34214505
Endolysosomal proteolysis and its regulationQ34607296
Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.Q34650693
Non-heme iron protein: a potential target of nitric oxide in acute cardiac allograft rejectionQ34866834
Labile iron pool: the main determinant of cellular response to oxidative stressQ35592855
Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinantQ36230570
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Nitric oxide, a biological effector. Electron paramagnetic resonance detection of nitrosyl-iron-protein complexes in whole cells.Q36436856
Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivoQ38320483
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Novel cellular defenses against iron and oxidation: ferritin and autophagocytosis preserve lysosomal stability in airway epitheliumQ40710014
Lysosomes, a meeting point of proteins, chaperones, and proteasesQ41700526
Release of iron from ferritin by xanthine oxidase. Role of the superoxide radicalQ41786699
Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblastsQ41814987
Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agentsQ41914732
The cellular labile iron pool and intracellular ferritin in K562 cellsQ41923255
Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.Q42136046
Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damageQ42156895
Lysosomal handling of cystine residues: stoichiometry of cysteine involvementQ42800203
Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages.Q43551018
Nitric oxide and peroxynitrite promote complete disruption of the [4Fe-4S] cluster of recombinant human iron regulatory protein 1.Q44234929
Anthracyclines induce accumulation of iron in ferritin in myocardial and neoplastic cells: inhibition of the ferritin iron mobilization pathwayQ44367233
Intralysosomal iron: a major determinant of oxidant-induced cell deathQ44426589
Reduction of disulfide bonds within lysosomes is a key step in antigen processingQ44824688
Iron catalyzes both decomposition and synthesis of S-nitrosothiols: optical and electron paramagnetic resonance studiesQ47686178
Cellular uptake and release of two contrasting iron chelators.Q52217004
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.Q53618951
Reductive mobilisation of ferritin iron.Q54526627
Ferritin iron kinetics and protein turnover in K562 cellsQ67980843
Cellular pharmacology of deferrioxamine B and derivatives in cultured rat hepatocytes in relation to iron mobilizationQ70104476
Autophagy of ferritin incorporated into the cytosol of Hela cells by liposomesQ71140333
Rapid mobilization of ferritin iron by ascorbate in the presence of oxygenQ71290357
Induction of iron-derived EPR signals in murine cancers by nitric oxide. Evidence for multiple intracellular targetsQ71610804
Isolation of mitochondria, mitochondrial membranes, lysosomes, peroxisomes, and Golgi membranes from rat liverQ72557288
Chelation and mobilization of cellular iron by different classes of chelatorsQ73328530
An EPR investigation of the products of the reaction of cytosolic and mitochondrial aconitases with nitric oxideQ73575338
Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibitionQ73643152
Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferaseQ73931678
Dinitrosyl iron complexes and S-nitrosothiols are two possible forms for stabilization and transport of nitric oxide in biological systemsQ77165708
P433issue3
P304page(s)345-352
P577publication date2006-11-29
P1433published inJournal of Biological Inorganic ChemistryQ3186899
P1476titleCrucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo
P478volume12

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cites work (P2860)
Q37140075Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide
Q53653673Formation of glutathionyl dinitrosyl iron complexes protects against iron genotoxicity.
Q43038484Formation of the distinct redox-interrelated forms of nitric oxide from reaction of dinitrosyl iron complexes (DNICs) and substitution ligands
Q36496301Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation
Q84672246New Members of the {Fe(NO)2}10 Dinitrosyliron Complexes Bound with [Thiolate, Thiolate] and [Amide, Amide] Ligations
Q39982443Nitric oxide-induced conversion of cellular chelatable iron into macromolecule-bound paramagnetic dinitrosyliron complexes
Q37885200Nitrosyl iron complexes--synthesis, structure and biology

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