Labile iron pool: the main determinant of cellular response to oxidative stress

scientific article published on October 2003

Labile iron pool: the main determinant of cellular response to oxidative stress is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.MRFMMM.2003.08.004
P698PubMed publication ID14637247

P50authorMarcin KruszewskiQ52882850
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectironQ677
P1104number of pages12
P304page(s)81-92
P577publication date2003-10-01
P1433published inMutation ResearchQ6943732
P1476titleLabile iron pool: the main determinant of cellular response to oxidative stress
P478volume531

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cites work (P2860)
Q390111663-Hydroxybutyrate dehydrogenase-2 and ferritin-H synergistically regulate intracellular iron
Q44286743A novel method for assessing the role of iron and its functional chelation in fibrin fibril formation: the use of scanning electron microscopy
Q34431813A role for human mitochondrial complex II in the production of reactive oxygen species in human skin
Q34327542A unified model for ferritin iron loading by the catalytic center: implications for controlling "free iron" during oxidative stress
Q37399385Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
Q42472923Adaptation of HepG2 cells to silver nanoparticles-induced stress is based on the pro-proliferative and anti-apoptotic changes in gene expression
Q90265033Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome
Q33433008Analysis of FeII-mediated decomposition of a linoleic acid-derived lipid hydroperoxide by liquid chromatography/mass spectrometry
Q87511104Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice
Q37833099Anticancer activity of metal complexes: involvement of redox processes
Q46873531Antioxidant activity, cellular bioavailability, and iron and calcium management of neuroprotective and nonneuroprotective flavones
Q39402253Antioxidants Mediate Both Iron Homeostasis and Oxidative Stress
Q36250103Biophysical investigation of the ironome of human jurkat cells and mitochondria
Q57046102Brain iron loading impairs DNA methylation and alters GABAergic function in mice
Q36107701CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia
Q34726654Caco-2 intestinal epithelial cells absorb soybean ferritin by mu2 (AP2)-dependent endocytosis
Q46522688Can hydroxyurea serve as a free radical scavenger and reduce iron overload in β-thalassemia patients?
Q58572012Carcinogenesis-related changes in iron metabolism in chronic obstructive pulmonary disease subjects with lung cancer
Q45223109Changes in skeletal muscle iron metabolism outpace amyotrophic lateral sclerosis onset in transgenic rats bearing the G93A hmSOD1 gene mutation
Q39238603Critical role of surface chemical modifications induced by length shortening on multi-walled carbon nanotubes-induced toxicity
Q49913738Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity.
Q40202675Crucial role of lysosomal iron in the formation of dinitrosyl iron complexes in vivo
Q34505918Decarbonylated cyclophilin A Cpr1 protein protects Saccharomyces cerevisiae KNU5377Y when exposed to stress induced by menadione
Q92039096Decrement in Cellular Iron and Reactive Oxygen Species, and Improvement of Insulin Secretion in a Pancreatic Cell Line Using Green Tea Extract
Q47130659Development of an iron-selective antioxidant probe with protective effects on neuronal function.
Q39125250Diallyl trisulfide is more cytotoxic to prostate cancer cells PC-3 than to noncancerous epithelial cell line PNT1A: a possible role of p66Shc signaling axis
Q41627433Dietary iron restriction alleviates renal tubulointerstitial injury induced by protein overload in mice.
Q39851313Differential effects of basolateral and apical iron supply on iron transport in Caco-2 cells
Q33925223Distinct roles of basal steady-state and induced H-ferritin in tumor necrosis factor-induced death in L929 cells
Q51797997Does the cellular labile iron pool participate in the oxidation of 2',7'-dichlorodihydrofluorescein?
Q28583219Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes
Q34479123Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells
Q91867157Early Actions of Neurotransmitters During Cortex Development and Maturation of Reprogrammed Neurons
Q36345315Effect of Nordic Walking training on iron metabolism in elderly women.
Q34764511Effect of cobalt on Escherichia coli metabolism and metalloporphyrin formation
Q33788123Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestatic liver disease
Q42715190Effects of DMSA-coated Fe3O4 nanoparticles on the transcription of genes related to iron and osmosis homeostasis
Q50002039Effects of an Acute Exercise Bout on Serum Hepcidin Levels.
Q39704027Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.
Q39439711Effects of the iron-chelating agent deferoxamine on triethylene glycol dimethacrylate, 2-hydroxylethyl methacrylate, hydrogen peroxide-induced cytotoxicity
Q33743674Endogenous siderophore 2,5-dihydroxybenzoic acid deficiency promotes anemia and splenic iron overload in mice
Q39631945Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence
Q50428368Epigallocatechin-3-Gallate Inhibition of Myeloperoxidase and Its Counter-Regulation by Dietary Iron and Lipocalin 2 in Murine Model of Gut Inflammation
Q34336346Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes
Q49571966Evaluation of the suitability of a Sprague Dawley rat model to assess intravenous iron preparations
Q28756680Exposure to nitric oxide protects against oxidative damage but increases the labile iron pool in sorghum embryonic axes
Q59132722Fenton reactions drive nucleotide and ATP syntheses in cancer
Q79263564Ferrous ion-induced strand breaks in the DNA plasmid pBR322 are not mediated by hydrogen peroxide
Q46877690Flow cytometry measurement of the labile iron pool in human hematopoietic cells
Q42053341Geoditin A induces oxidative stress and apoptosis on human colon HT29 cells
Q37319051Getting the iron out: phlebotomy for Alzheimer's disease?
Q45780176Glutathione and ascorbic acid protect Arabidopsis plants against detrimental effects of iron deficiency
Q93007291Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells
Q39374219Hydrogen peroxide signals E. coli phagocytosis by human polymorphonuclear cells; up-stream and down-stream pathway
Q39485547Impact of JNK1, JNK2, and ligase Itch on reactive oxygen species formation and survival of prostate cancer cells treated with diallyl trisulfide.
Q35795910Impaired iron status in aging research
Q53058280Inactivation of natural enteric bacteria in real municipal wastewater by solar photo-Fenton at neutral pH.
Q28564304Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy
Q41903364Increased labile iron pool in sorghum embryonic axes after the exogenous application of nitric oxide is independent on the nature of the NO donor
Q28572077Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
Q28391762Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease
Q91446312Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver
Q34662248Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress.
Q38758071Investigation into the distinct subcellular effects of docosahexaenoic acid loaded low-density lipoprotein nanoparticles in normal and malignant murine liver cells
Q52575650Involvement of cytosolic and mitochondrial iron in iron overload cardiomyopathy: an update.
Q39752431Involvement of fumarase C and NADH oxidase in metabolic adaptation of Pseudomonas fluorescens cells evoked by aluminum and gallium toxicity
Q51654265Iron Regulatory Protein 1 Suppresses Hypoxia-Induced Iron Uptake Proteins Expression and Decreases Iron Levels in HepG2 Cells.
Q33349194Iron and porphyrin trafficking in heme biogenesis
Q35107121Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction
Q96815966Iron imaging in myocardial infarction reperfusion injury
Q64076840Iron in Neurodegeneration - Cause or Consequence?
Q53219528Iron reduction by deferoxamine leads to amelioration of adiposity via the regulation of oxidative stress and inflammation in obese and type 2 diabetes KKAy mice.
Q53611817Iron restriction inhibits renal injury in aldosterone/salt-induced hypertensive mice.
Q51109964Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation.
Q37982648Iron toxicity in neurodegeneration.
Q36448391Iron-Mediated Lysosomal Membrane Permeabilization in Ethanol-Induced Hepatic Oxidative Damage and Apoptosis: Protective Effects of Quercetin
Q36210908Iron-binding drugs targeted to lysosomes: a potential strategy to treat inflammatory lung disorders
Q58611278Iron-sensing is governed by mitochondrial, not by cytosolic iron-sulfur cluster biogenesis in Aspergillus fumigatus
Q89977600JNK/p66Shc/ITCH Signaling Pathway Mediates Angiotensin II-induced Ferritin Degradation and Labile Iron Pool Increase
Q38198634Labile iron in cells and body fluids: physiology, pathology, and pharmacology
Q92316210Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism
Q36936201Lipocalin 2 alleviates iron toxicity by facilitating hypoferremia of inflammation and limiting catalytic iron generation
Q37079830Lysosomes in iron metabolism, ageing and apoptosis
Q37502811Mammalian iron transport.
Q34258603Mammalian siderophores, siderophore-binding lipocalins, and the labile iron pool
Q36625486Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.
Q27010510Mechanisms of mammalian iron homeostasis
Q40360282Metallothionein protects against oxidative stress-induced lysosomal destabilization
Q90963905Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo
Q37750239Mitochondrial iron metabolism and its role in neurodegeneration.
Q37529459Modification of fibrin structure as a possible cause of thrombolytic resistance
Q37719690Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease
Q39982443Nitric oxide-induced conversion of cellular chelatable iron into macromolecule-bound paramagnetic dinitrosyliron complexes
Q33931109Nitrosothiol formation and protection against Fenton chemistry by nitric oxide-induced dinitrosyliron complex formation from anoxia-initiated cellular chelatable iron increase
Q36336362Non transferrin bound iron: nature, manifestations and analytical approaches for estimation
Q41039597Nordic walking training attenuation of oxidative stress in association with a drop in body iron stores in elderly women.
Q38602976Novel evidence for complement system activation in chick myopia and hyperopia models: a meta-analysis of transcriptome datasets
Q90396713Oxidative Stress in Peritoneal Dialysis Patients: Association with the Dialysis Adequacy and Technique Survival
Q34406062Oxidative stress and modification of renal vascular permeability are associated with acute kidney injury during P. berghei ANKA infection
Q28082925Oxidative stress and the homeodynamics of iron metabolism
Q26746899Parkinson's Disease: The Mitochondria-Iron Link
Q33677951Power of proteomics in linking oxidative stress and female infertility
Q91583489Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity
Q46829144Prolonged swimming promotes cellular oxidative stress and p66Shc phosphorylation, but does not induce oxidative stress in mitochondria in the rat heart.
Q36265573Protective Effects of Tinospora crispa Stem Extract on Renal Damage and Hemolysis during Plasmodium berghei Infection in Mice
Q57806981Protective Role of Histidine Supplementation Against Oxidative Stress Damage in the Management of Anemia of Chronic Kidney Disease
Q43100126Pulmonary oxidative stress, inflammation, and dysregulated iron homeostasis in rat models of cardiovascular disease
Q53513733Quantitative comparison of different iron forms in the temporal cortex of Alzheimer patients and control subjects.
Q38391853Quantitative proteome profiling of dystrophic dog skeletal muscle reveals a stabilized muscular architecture and protection against oxidative stress after systemic delivery of MuStem cells.
Q36979046Quercitrin protects skin from UVB-induced oxidative damage
Q34400123Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice
Q48180266Reduction of Skeletal Muscle Power in Adolescent Males Carrying H63D Mutation in the HFE Gene.
Q46614360Reduction of a marker of oxidative stress with enhancement of iron utilization by erythropoiesis activation following epoetin beta pegol administration in iron-loaded db/db mice
Q34245810Reliability of serum assays of iron status in postmenopausal women
Q33713928Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide
Q41889986Siderophore-mediated iron trafficking in humans is regulated by iron
Q33582136Simple sugar supplementation abrogates exercise-induced increase in hepcidin in young men.
Q43321279Solar disinfection of fungal spores in water aided by low concentrations of hydrogen peroxide.
Q98224443Spotlight on Ferroptosis: Iron-Dependent Cell Death in Alzheimer's Disease
Q49137107Sub-chronic iron overload triggers oxidative stress development in rat brain: implications for cell protection
Q51758684The Aging of Iron Man.
Q38496987The Labile Side of Iron Supplementation in CKD
Q36421222The autophagic lysosomal system in outflow pathway physiology and pathophysiology.
Q58068814The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials
Q38913176The impairment of methylmenaquinol:fumarate reductase affects hydrogen peroxide susceptibility and accumulation in Campylobacter jejuni
Q88376716The labile iron pool attenuates peroxynitrite-dependent damage and can no longer be considered solely a pro-oxidative cellular iron source
Q37832421The many faces of the octahedral ferritin protein
Q35055739The redox basis of epigenetic modifications: from mechanisms to functional consequences.
Q30852753The role of iron in brain ageing and neurodegenerative disorders.
Q26859190The role of iron-induced fibrin in the pathogenesis of Alzheimer's disease and the protective role of magnesium
Q90169753Therapeutic targeting of SDHB-mutated pheochromocytoma/paraganglioma with pharmacologic ascorbic acid
Q46876143Topical applications of iron chelators in photosensitization
Q24289511Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
Q30483384Transcriptomic and genomic evolution under constant cold in Antarctic notothenioid fish
Q47109274Transferrin receptor 1 upregulation in primary tumor and downregulation in benign kidney is associated with progression and mortality in renal cell carcinoma patients
Q40180776Uptake and Toxicity of Hemin and Iron in Cultured Mouse Astrocytes.
Q42701991Uptake of non-transferrin iron by erythroid cells
Q46753916Variable inhibitory effects on the formation of dinitrosyl iron complexes by deferoxamine and salicylaldehyde isonicotinoyl hydrazone in K562 cells
Q42484365Vesicular transport and apotransferrin in intestinal iron absorption, as shown in the Caco-2 cell model
Q91886008Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name
Q42819443Zinc deficiency-induced iron accumulation, a consequence of alterations in iron regulatory protein-binding activity, iron transporters, and iron storage proteins
Q36570631siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake

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