Mammalian siderophores, siderophore-binding lipocalins, and the labile iron pool

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Mammalian siderophores, siderophore-binding lipocalins, and the labile iron pool is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.R111.311829
P932PMC publication ID3340207
P698PubMed publication ID22389496

P2093author name stringRoland K Strong
Colin Correnti
P2860cites workCharacterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenaseQ24299964
Anthrax pathogen evades the mammalian immune system through stealth siderophore productionQ24675112
Siderophore-based iron acquisition and pathogen controlQ24681774
Enterobactin: an archetype for microbial iron transportQ24683689
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisitionQ27640027
Cell transformation by the v-myc oncogene abrogates c-Myc/Max-mediated suppression of a C/EBP beta-dependent lipocalin geneQ27642238
Structure of the human transferrin receptor-transferrin complexQ27643181
The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport 1Q27651418
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complexQ27662810
The v-myc-induced Q83 Lipocalin Is a SiderocalinQ27664382
Transferrin receptor is necessary for development of erythrocytes and the nervous systemQ28118509
Lack of a role for iron in the Lyme disease pathogenQ28145506
An iron delivery pathway mediated by a lipocalinQ28216116
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory networkQ28280607
Two to tango: regulation of Mammalian iron metabolismQ28287034
A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin productionQ28511945
The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptakeQ28577988
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptakeQ28587213
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injuryQ28591880
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating ironQ29619561
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathwayQ30494299
Molecular and biological analysis of eight genetic islands that distinguish Neisseria meningitidis from the closely related pathogen Neisseria gonorrhoeaeQ30847631
Mineralization in ferritin: an efficient means of iron storageQ33707673
Biochemistry of iron uptakeQ33775784
The iron transporter DMT1.Q33785097
The Yersinia high-pathogenicity island: an iron-uptake islandQ33952323
Microorganisms pumping iron: anaerobic microbial iron oxidation and reductionQ33999612
Living with iron (and oxygen): questions and answers about iron homeostasisQ34055551
Siderophores: Structure and Function of Microbial Iron Transport CompoundsQ34058117
Redox cycling in iron uptake, efflux, and traffickingQ34094269
Stoichiometric and site characteristics of the binding of iron to human transferrinQ34115007
The role of iron in the immune response to bacterial infectionQ34155194
The roles of iron in health and diseaseQ34156115
Iron withholding: a defense against infection and neoplasiaQ34259767
Microbial iron compoundsQ34260986
Ironing out disease: inherited disorders of iron homeostasisQ34289732
Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestrationQ34383190
Microbial evasion of the immune system: structural modifications of enterobactin impair siderocalin recognitionQ34559548
Dual action of neutrophil gelatinase-associated lipocalinQ34603152
The role of electrostatics in siderophore recognition by the immunoprotein SiderocalinQ34893809
Siderocalins: siderophore-binding proteins of the innate immune systemQ34934297
The labile iron pool: characterization, measurement, and participation in cellular processes(1).Q34956696
Chemistry for an essential biological process: the reduction of ferric ironQ34983143
Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3Q35063479
Transferrin-iron uptake by Gram-negative bacteriaQ35109508
Trace Element Uptake and Distribution in PlantsQ35121120
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2.Q35133896
Labile iron pool: the main determinant of cellular response to oxidative stressQ35592855
Transferrins and heme-compounds as iron sources for pathogenic bacteriaQ35868925
Bacterial iron sources: from siderophores to hemophoresQ35919884
Amonabactin, a novel tryptophan- or phenylalanine-containing phenolate siderophore in Aeromonas hydrophilaQ36175468
ColV plasmid-specific aerobactin synthesis by invasive strains of Escherichia coliQ36426029
Forging a field: the golden age of iron biologyQ36742479
Intracellular labile iron.Q36798824
Lipocalin 2 promotes breast cancer progressionQ37129437
Iron transport & homeostasis mechanisms: their role in health & disease.Q37357647
Lipocalin-2: pro- or anti-apoptotic?Q37374543
Mammalian iron transport.Q37502811
Mammalian iron metabolismQ37658680
Iron regulatory proteins: from molecular mechanisms to drug developmentQ37705384
Ironing out the wrinkles in host defense: interactions between iron homeostasis and innate immunityQ37726751
Low molecular weight intracellular iron transport compoundsQ39634380
Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophoresQ39954600
Lipocalin 2 is required for BCR-ABL-induced tumorigenesisQ39956362
Isolation and characterization of a siderophore-like growth factor from mutants of SV40-transformed cells adapted to picolinic acidQ40170600
Iron piracy: acquisition of transferrin-bound iron by bacterial pathogensQ40506099
Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivationQ40788252
Transferrin receptor of the rabbit reticulocyteQ41052150
Iron, infections, and anemia of inflammationQ41632665
Function and regulation of transferrin and ferritin.Q41699844
Low molecular weight iron-binding factor from mammalian tissue that potentiates bacterial growthQ42019610
Structure of schizokinen, an iron-transport compound from Bacillus megateriumQ44537674
Catechol releases iron(III) from ferritin by direct chelation without iron(II) production.Q45258496
Bcr-Abl-mediated suppression of normal hematopoiesis in leukemiaQ45286107
On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute responseQ46690537
The aerobactin iron transport system genes in Shigella flexneri are present within a pathogenicity island.Q47945948
Acute phase lipocalin Ex-FABP is involved in heart development and cell survival.Q52087233
Formation of Iron-binding Compounds by Micro-organismsQ58934886
Mechanism of catalysis of Fe(II) oxidation by ferritin H chainsQ67518821
Domain preference in iron removal from human transferrin by the bacterial siderophores aerobactin and enterochelinQ70067055
The occurrence of carboxymycobactin, the siderophore of pathogenic mycobacteria, as a second extracellular siderophore in Mycobacterium smegmatisQ71519595
Inhibition of cell proliferation and induction of apoptosis by ExFABP gene targetingQ73735851
A Preorganized Siderophore: Thermodynamic and Structural Characterization of Alcaligin and Bisucaberin, Microbial Macrocyclic Dihydroxamate Chelating Agents(1)Q74832610
From a total synthesis of cepabactin and its 3:1 ferric complex to the isolation of a 1:1:1 mixed complex between iron (III), cepabactin and pyochelinQ81474297
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)13524-13531
P577publication date2012-03-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleMammalian siderophores, siderophore-binding lipocalins, and the labile iron pool
P478volume287

Reverse relations

cites work (P2860)
Q37716856"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels
Q36708605A manganese-rich environment supports superoxide dismutase activity in a Lyme disease pathogen, Borrelia burgdorferi
Q35804193A systematic analysis of human lipocalin family and its expression in esophageal carcinoma
Q92575586ASP2397 Is a Novel Natural Compound That Exhibits Rapid and Potent Fungicidal Activity against Aspergillus Species through a Specific Transporter
Q38955294An overview of the biological metal uptake pathways in Pseudomonas aeruginosa.
Q38369809Bacterial siderophores promote plant growth: Screening of catechol and hydroxamate siderophores.
Q34298407Bacterial siderophores that evade or overwhelm lipocalin 2 induce hypoxia inducible factor 1α and proinflammatory cytokine secretion in cultured respiratory epithelial cells.
Q38368718Diverging roles of bacterial siderophores during infection.
Q92190432Draft genomes and initial characteriaztion of siderophore producing pseudomonads isolated from mine dump and mine drainage
Q37551280Human Metabolome-derived Cofactors Are Required for the Antibacterial Activity of Siderocalin in Urine
Q35783053Human Urinary Composition Controls Antibacterial Activity of Siderocalin
Q46249324In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection.
Q28082191Iron and zinc exploitation during bacterial pathogenesis
Q50892902Iron depletion strategy for targeted cancer therapy: utilizing the dual roles of neutrophil gelatinase-associated lipocalin protein.
Q37376232Iron in intracellular infection: to provide or to deprive?
Q38066761Iron speciation in the cytosol: an overview
Q38187484Iron: the hard player in diabetes pathophysiology.
Q36140013Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.
Q34735792Lipocalin-2 as mediator of chemokine expression and granulocyte infiltration during ischemia and reperfusion
Q36655357Lipopolysaccharide-induced inflammation or unilateral ureteral obstruction yielded multiple types of glycosylated Lipocalin 2
Q34490463Metal limitation and toxicity at the interface between host and pathogen
Q49958535Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice
Q39014492Molecular basis of mycobacterial survival in macrophages
Q28536426N-octanoyl dopamine inhibits the expression of a subset of κB regulated genes: potential role of p65 Ser276 phosphorylation
Q97545704Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands
Q36333948Preparation of 3-benzyloxy-2-pyridinone functional linkers: Tools for the synthesis of 3,2-hydroxypyridinone (HOPO) and HOPO/hydroxamic acid chelators
Q42253266Prospects for treating osteoarthritis: enzyme-protein interactions regulating matrix metalloproteinase activity.
Q35924321Purification and Structural Characterization of "Simple Catechol", the NGAL-Siderocalin Siderophore in Human Urine
Q26784135Roles of bacterial and mammalian siderophores in host-pathogen interactions
Q21131297Shared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans
Q57365954Siderophore-inspired nanoparticle-based biosensor for the selective detection of Fe3+
Q30243906Siderophores; iron scavengers: the novel & promising targets for pathogen specific antifungal therapy
Q30796767Synthesis, spectroscopy, and binding constants of ketocatechol-containing iminodiacetic acid and its Fe(III), Cu(II), and Zn(II) complexes and reaction of Cu(II) complex with H₂O₂ in aqueous solution
Q34819468Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum
Q37238644The Ligands of Neutrophil Gelatinase-Associated Lipocalin
Q47098548The Metallophore Staphylopine Enables Staphylococcus aureus To Compete with the Host for Zinc and Overcome Nutritional Immunity.
Q38704529The Yin and Yang of copper during infection
Q51014926The fate of siderophores: antagonistic environmental interactions in exudate-mediated micronutrient uptake.
Q88995043The iron hand of uropathogenic Escherichia coli: the role of transition metal control in virulence
Q28109405The iron metallome in eukaryotic organisms
Q58593664Tonicity inversely modulates lipocalin-2 (Lcn2/24p3/NGAL) receptor (SLC22A17) and Lcn2 expression via Wnt/β-catenin signaling in renal inner medullary collecting duct cells: implications for cell fate and bacterial infection
Q37511583Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis

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