Redox cycling in iron uptake, efflux, and trafficking

scientific article

Redox cycling in iron uptake, efflux, and trafficking is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1074/JBC.R110.113217
P932PMC publication ID2930670
P698PubMed publication ID20522542

P2093author name stringDaniel J Kosman
P2860cites workCopper Deficiency Myelopathy (Human Swayback)Q21128629
The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease geneQ24336948
The Steap proteins are metalloreductasesQ24681553
The high-resolution X-ray crystallographic structure of the ferritin (EcFtnA) of Escherichia coli; comparison with human H ferritin (HuHF) and the structures of the Fe(3+) and Zn(2+) derivativesQ27630676
Evidence for iron channeling in the Fet3p-Ftr1p high-affinity iron uptake complex in the yeast plasma membraneQ27930246
The iron transporter Fth1p forms a complex with the Fet5 iron oxidase and resides on the vacuolar membraneQ27931127
Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transportQ27931684
Identification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization.Q27931968
Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae.Q27932987
Spectral and kinetic properties of the Fet3 protein from Saccharomyces cerevisiae, a multinuclear copper ferroxidase enzymeQ27933663
A role for the Saccharomyces cerevisiae ATX1 gene in copper trafficking and iron transportQ27933943
CCC1 is a transporter that mediates vacuolar iron storage in yeastQ27935526
The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptakeQ27935957
The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptakeQ27937767
Assembly, activation, and trafficking of the Fet3p.Ftr1p high affinity iron permease complex in Saccharomyces cerevisiaeQ27937889
A permease-oxidase complex involved in high-affinity iron uptake in yeastQ27938637
Fre1p Cu2+ reduction and Fet3p Cu1+ oxidation modulate copper toxicity in Saccharomyces cerevisiaeQ27938948
The metalloreductase Fre6p in Fe-efflux from the yeast vacuoleQ27940317
An iron-regulated ferric reductase associated with the absorption of dietary ironQ28202796
Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolismQ28204979
Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasminQ28212806
Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouseQ28238774
Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia miceQ28241576
Kinetic Studies of Ferrous Ion Oxidation with Crystalline Human Ferroxidase (Ceruloplasmin)Q28257419
Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding proteinQ28269062
Isolation of a partial candidate gene for Menkes disease by positional cloningQ28269072
Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPaseQ28269082
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouseQ28297185
Reassessing the first appearance of eukaryotes and cyanobacteriaQ28298472
Identification and functional expression of HAH1, a novel human gene involved in copper homeostasisQ28306709
Decreased hephaestin activity in the intestine of copper-deficient mice causes systemic iron deficiencyQ28307150
Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brainQ28575311
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cellsQ28594532
nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouseQ28594752
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione coupleQ29615232
Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cellsQ33283960
Multicopper Oxidases and OxygenasesQ33957458
The copper-iron connection in biology: structure of the metallo-oxidase Fet3pQ34084089
Copper-dependent iron assimilation pathway in the model photosynthetic eukaryote Chlamydomonas reinhardtiiQ34100701
Human copper-transporting ATPase ATP7B (the Wilson's disease protein): biochemical properties and regulationQ34172003
Function, structure, and mechanism of intracellular copper trafficking proteinsQ34275487
Old iron, young copper: from Mars to VenusQ34338955
The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes geneQ34348941
Mapping, cloning and genetic characterization of the region containing the Wilson disease gene.Q34348948
ATP7B (WND) proteinQ34476659
Molecular and pathological basis of aceruloplasminemiaQ34566666
Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degenerationQ34690797
Chemistry for an essential biological process: the reduction of ferric ironQ34983143
FET3P, ceruloplasmin, and the role of copper in iron metabolismQ34989954
The ceruloplasmin homolog hephaestin and the control of intestinal iron absorption.Q35053272
Studies on copper metabolism. XIV. Copper, ceruloplasmin and oxidase activity in sera of normal human subjects, pregnant women, and patients with infection, hepatolenticular degeneration and the nephrotic syndromeQ35288913
Recent advances in swayback.Q35838682
A system's view of the evolution of lifeQ36794091
Steap proteins: implications for iron and copper metabolismQ36908821
Copper transport into the secretory pathway is regulated by oxygen in macrophagesQ37166075
The Fox1 ferroxidase of Chlamydomonas reinhardtii: a new multicopper oxidase structural paradigmQ37175759
Iron feeding induces ferroportin 1 and hephaestin migration and interaction in rat duodenal epitheliumQ37325173
Ferric reductase of Saccharomyces cerevisiae: molecular characterization, role in iron uptake, and transcriptional control by ironQ37599208
Timing of morphological and ecological innovations in the cyanobacteria--a key to understanding the rise in atmospheric oxygenQ39934766
Ferroxidases and ferrireductases: their role in iron metabolismQ39949314
Mechanism of Fe(II) oxidation and core formation in ferritin.Q40610759
Ferric iron reduction and iron uptake in eucaryotes: studies with the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe.Q40610876
Role of ceruloplasmin in macrophage iron efflux during hypoxiaQ40638208
Molecular evidence for the role of a ferric reductase in iron transportQ40708630
Functional properties of the copper-transporting ATPase ATP7B (the Wilson's disease protein) expressed in insect cellsQ40772654
Functional analysis and intracellular localization of the human menkes protein (MNK) stably expressed from a cDNA construct in Chinese hamster ovary cells (CHO-K1).Q41024542
Some properties of coupled iron-caeruloplasmin oxidation systemsQ42172581
Aceruloplasminemia, an inherited disorder of iron metabolismQ42436733
Aceruloplasminemia, an iron metabolic disorderQ42455448
The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidaseQ42488518
Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasminQ42743122
Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.Q44217143
The involvement of a multicopper oxidase in iron uptake by the green algae Chlamydomonas reinhardtii.Q44248356
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous systemQ44438522
Decreased hephaestin expression and activity leads to decreased iron efflux from differentiated Caco2 cells.Q45931539
Evolution was chemically constrained.Q48431611
Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.Q48525934
Investigations in Serum Copper. II. Isolation of the Copper Containing Protein, and a Description of some of its PropertiesQ56446390
Copper deficiency-associated myelopathy in a 45-year-old womanQ57308366
Intramembrane Bis-Heme Motif for Transmembrane Electron Transport Conserved in a Yeast Iron Reductase and the Human NADPH OxidaseQ59512350
The FRE1 Ferric Reductase ofSaccharomyces cerevisiaeIs a CytochromebSimilar to That of NADPH OxidaseQ59512359
Iron storage in Saccharomyces cerevisiaeQ68133891
Relationship between anemia and cholesterol metabolism in 'sex-linked anemic' (gene symbol, sla) mouseQ69885556
Mobilization of liver iron by ferroxidase (ceruloplasmin)Q71261803
The Mobilization of Iron from the Perfused Mammalian Liver by a Serum Copper Enzyme, Ferroxidase IQ71782353
Ceruloplasmin and the reactions forming diferric transferrinQ71792549
Iron sequestration by the yeast vacuole. A study with vacuolar mutants of Saccharomyces cerevisiaeQ72130210
The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serumQ72782520
Studies on copper metabolism. IV. The influence of copper on the absorption of ironQ73065857
Studies on copper metabolism. II. Hematologic manifestations of copper deficiency in swineQ74037327
Studies on copper metabolism. III. The metabolism of iron in copper deficient swineQ74037334
Cloning and gastrointestinal expression of rat hephaestin: relationship to other iron transport proteinsQ74514594
P433issue35
P407language of work or nameEnglishQ1860
P304page(s)26729-26735
P577publication date2010-06-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleRedox cycling in iron uptake, efflux, and trafficking
P478volume285

Reverse relations

cites work (P2860)
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