| scholarly article | Q13442814 |
| P50 | author | Scheherazade Sadegh-Nasseri | Q45276659 |
| P2860 | cites work | HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides | Q24294751 |
| The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3 | Q24303524 | ||
| The lymph as a pool of self-antigens | Q42672113 | ||
| A kinetic intermediate in the reaction of an antigenic peptide and I-Ek | Q43440073 | ||
| Specific role for cathepsin S in the generation of antigenic peptides in vivo | Q43867816 | ||
| Sibling rivalry: competition between MHC class II family members inhibits immunity | Q44284098 | ||
| Activation of lysosomal function during dendritic cell maturation | Q44333919 | ||
| Interaction of peptide antigens and class II major histocompatibility complex antigens | Q45044764 | ||
| Allocation of helper T-cell epitope immunodominance according to three-dimensional structure in the human immunodeficiency virus type I envelope glycoprotein gp120. | Q45735715 | ||
| Structural intermediates in the reactions of antigenic peptides with MHC molecules. | Q45940913 | ||
| Intracellular transport of class II MHC molecules directed by invariant chain. | Q45941447 | ||
| Formation of a highly peptide-receptive state of class II MHC. | Q46139976 | ||
| Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways | Q46424023 | ||
| An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules | Q24309308 | ||
| HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading | Q24318038 | ||
| Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading | Q24328923 | ||
| The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity | Q24555648 | ||
| Small molecules that enhance the catalytic efficiency of HLA-DM | Q24623411 | ||
| MHC Class II Auto-Antigen Presentation is Unconventional | Q26800138 | ||
| HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism | Q27675409 | ||
| Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection | Q27675568 | ||
| Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange | Q27675571 | ||
| Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide | Q27684590 | ||
| Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide | Q27731272 | ||
| The Structure of HLA-DM, the Peptide Exchange Catalyst that Loads Antigen onto Class II MHC Molecules during Antigen Presentation | Q27765680 | ||
| Exogenous antigens bind MHC class II first, and are processed by cathepsins later | Q28084268 | ||
| Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides | Q28202956 | ||
| A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway | Q28266815 | ||
| Mice lacking the MHC class II-associated invariant chain | Q28507606 | ||
| Defective Antigen Processing in GILT-Free Mice | Q28586564 | ||
| Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus | Q28613227 | ||
| Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1 | Q28776057 | ||
| SYFPEITHI: database for MHC ligands and peptide motifs | Q29616214 | ||
| HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation | Q30434689 | ||
| Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65). | Q30454241 | ||
| Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data | Q30814677 | ||
| HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide | Q33292091 | ||
| HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available | Q33384128 | ||
| An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. | Q33548677 | ||
| Refolding and reassembly of separate alpha and beta chains of class II molecules of the major histocompatibility complex leads to increased peptide-binding capacity | Q33606693 | ||
| Pathways of antigen processing | Q33631854 | ||
| Direct observation of disordered regions in the major histocompatibility complex class II-associated invariant chain | Q33878348 | ||
| Proteolysis in MHC class II antigen presentation: who's in charge? | Q33885986 | ||
| Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain | Q52552855 | ||
| Short peptide sequences mimic HLA-DM functions. | Q52685879 | ||
| Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. | Q54102029 | ||
| Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells | Q58323390 | ||
| A role for peptide in determining MHC class II structure | Q59077345 | ||
| Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules | Q59096640 | ||
| Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes | Q59098594 | ||
| Activation of type B T cells after protein immunization reveals novel pathways of in vivo presentation of peptides | Q64449276 | ||
| Capacity of intact proteins to bind to MHC class II molecules | Q69741058 | ||
| Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments | Q71843540 | ||
| Intact proteins can bind to class II histocompatibility molecules with high affinity | Q73721633 | ||
| Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing | Q73827781 | ||
| Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice | Q74595052 | ||
| Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides | Q77320371 | ||
| The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed | Q77353669 | ||
| Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules | Q77436913 | ||
| One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules | Q77994488 | ||
| Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-Ad | Q37519795 | ||
| Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection | Q37672424 | ||
| Routes to manipulate MHC class II antigen presentation | Q37812880 | ||
| Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase | Q37867108 | ||
| Expanding roles for GILT in immunity | Q38067944 | ||
| HLA-DO and Its Role in MHC Class II Antigen Presentation. | Q38134729 | ||
| Determinants of immunodominance for CD4 T cells | Q38313559 | ||
| Dominance and crypticity of T cell antigenic determinants | Q40486347 | ||
| APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells. | Q40656630 | ||
| Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM. | Q40676502 | ||
| Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice | Q40814359 | ||
| Invariant chain structure and MHC class II function | Q40968427 | ||
| Mediation by HLA-DM of dissociation of peptides from HLA-DR | Q41333614 | ||
| Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments | Q41412265 | ||
| Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells | Q41440525 | ||
| MHC class II function preserved by low-affinity peptide interactions preceding stable binding | Q41447819 | ||
| Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures | Q41450247 | ||
| Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes | Q41515448 | ||
| Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant | Q41589934 | ||
| The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide | Q41640226 | ||
| Selection of the MHC Class II-associated peptide repertoire by HLA-DM | Q41649540 | ||
| Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments | Q41695026 | ||
| Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding | Q41731115 | ||
| The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route | Q41737562 | ||
| T cell recognition of fibrinogen. A determinant on the A alpha-chain does not require processing. | Q41912354 | ||
| MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding | Q41941589 | ||
| Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes | Q41944480 | ||
| Whole proteomes as internal standards in quantitative proteomics | Q41966883 | ||
| A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing | Q42015843 | ||
| Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1. | Q42617265 | ||
| Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii. | Q42661328 | ||
| Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding | Q33920167 | ||
| The kinetic basis of peptide exchange catalysis by HLA-DM | Q33947777 | ||
| Cutting edge: HLA-DM functions through a mechanism that does not require specific conserved hydrogen bonds in class II MHC-peptide complexes | Q34028384 | ||
| Isolation and characterization of the intracellular MHC class II compartment. | Q34340778 | ||
| HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes. | Q34483195 | ||
| Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources | Q34561569 | ||
| A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. | Q34679722 | ||
| The convergent roles of tapasin and HLA-DM in antigen presentation. | Q34784992 | ||
| Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes | Q34831727 | ||
| HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation | Q34948997 | ||
| Lysosomal cysteine proteases regulate antigen presentation | Q35140806 | ||
| Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis | Q35825742 | ||
| The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM. | Q35861946 | ||
| How MHC class II molecules work: peptide-dependent completion of protein folding. | Q35873641 | ||
| A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex | Q36230650 | ||
| The lysosomal cysteine proteases in MHC class II antigen presentation | Q36266499 | ||
| Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. | Q36301521 | ||
| HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives | Q36303660 | ||
| Endosomal proteases in antigen presentation | Q36336164 | ||
| Two-gene control of the expression of a murine Ia antigen | Q36341979 | ||
| Regulation of antigen presentation by acidic pH. | Q36351024 | ||
| Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain | Q36353070 | ||
| A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides | Q36362737 | ||
| Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CL | Q36367626 | ||
| HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules | Q36377428 | ||
| Heterogeneity and plasticity of T helper cells | Q36388771 | ||
| HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. | Q36404572 | ||
| An integrative bioinformatic approach for studying escape mutations in human immunodeficiency virus type 1 gag in the Pumwani Sex Worker Cohort | Q36483367 | ||
| The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity | Q36674612 | ||
| Extracellular antigen processing and presentation by immature dendritic cells | Q36780502 | ||
| Proteases: essential actors in processing antigens and intracellular toll-like receptors. | Q37193064 | ||
| HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1. | Q37345643 | ||
| Cathepsin S activity regulates antigen presentation and immunity | Q37382422 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1305 | |
| P577 | publication date | 2016-01-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | F1000Research | Q27701587 |
| P1476 | title | A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells | |
| P478 | volume | 5 |
| Q64114857 | Cathepsin L promotes secretory IgA response by participating in antigen presentation pathways during Mycoplasma Hyopneumoniae infection |
| Q42054161 | Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing |
| Q40445297 | HLA-DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model |
| Q58608551 | Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition |
| Q55084358 | Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection |
| Q92651121 | Structure and Function of Molecular Chaperones that Govern Immune Peptide Loading |
| Q60944020 | The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation |
Search more.