SYFPEITHI: database for MHC ligands and peptide motifs

scientific article (publication date: November 1999)

SYFPEITHI: database for MHC ligands and peptide motifs is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P6179Dimensions Publication ID1019170092
P356DOI10.1007/S002510050595
P3181OpenCitations bibliographic resource ID915730
P698PubMed publication ID10602881

P2093author name stringBachmann J
Stevanović S
Bachor OA
Emmerich NP
Rammensee H
P433issue3-4
P407language of work or nameEnglishQ1860
P921main subjectdatabaseQ8513
P304page(s)213-9
P577publication date1999-11-01
P1433published inImmunogeneticsQ15709984
P1476titleSYFPEITHI: database for MHC ligands and peptide motifs
P478volume50

Reverse relations

cites work (P2860)
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Q45868889Activation of CFTR-specific T Cells in cystic fibrosis mice following gene transfer.
Q35850673Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities
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Q24634560Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1
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Q47672626Allergenicity Assessment of Transgenic Wheat Lines In Silico
Q37514725Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study
Q37696017Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses
Q40207805Alteration of epitope recognition pattern in Ag85B and ESAT-6 has a profound influence on vaccine-induced protection against Mycobacterium tuberculosis
Q92297076Alternative mRNA splicing in cancer immunotherapy
Q28743226Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires
Q27485470Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire
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Q45918640Antitopes define preferential proteasomal cleavage site usage.
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Q35048340Aspects of cancer immunotherapy
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Q90266059Autoimmunity (or Not) in Atopic Dermatitis
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Q47615055Automatic sequence design of major histocompatibility complex class I binding peptides impairing CD8+ T cell recognition
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Q36471836Autophagy and antigen presentation
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Q36406535Autophagy in innate and adaptive immunity against intracellular pathogens.
Q26864841Autophagy in innate recognition of pathogens and adaptive immunity
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Q90610394CD8+ Cytotoxic T Lymphocyte Responses and Viral Epitope Escape in Acute HIV-1 Infection
Q33942390CD8+ T cell recognition of polymorphic wild-type sequence p53(65-73) peptides in squamous cell carcinoma of the head and neck
Q43843631CD8+ T cell response in HLA-A*0201 transgenic mice is elicited by epitopes from SARS-CoV S protein
Q33305428CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation
Q37358997CD8+ T cells in type 1 diabetes
Q35871310CD8+ T cells specific for the androgen receptor are common in patients with prostate cancer and are able to lyse prostate tumor cells
Q40010732CD8+ T-cell responses to tumor-associated antigens correlate with superior relapse-free survival after allo-SCT.
Q42282904CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells
Q44925388CD8+ suppressor-mediated regulation of human CD4+ T cell responses to glutamic acid decarboxylase 65.
Q21263133CED: a conformational epitope database
Q31010282CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope
Q39533424CTL recognition of a novel HLA-A*0201-binding peptide derived from glioblastoma multiforme tumor cells
Q36413180CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer
Q38209294Can we predict mutant neoepitopes in human cancers for patient-specific vaccine therapy?
Q37148184Cancer genome sequencing and its implications for personalized cancer vaccines
Q35948346Candidate epitope identification using peptide property models: application to cancer immunotherapy
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Q35946943Cellular and humoral immune responses to alphavirus replicon vaccines expressing cytomegalovirus pp65, IE1, and gB proteins
Q36230842Cellular immune responses in hemophilia: why do inhibitors develop in some, but not all hemophiliacs?
Q24791721Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa
Q39215865Characterization of Ewing sarcoma associated cancer/testis antigens
Q55028507Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool.
Q40512504Characterization of mouse MAGE-derived H-2Kb-restricted CTL epitopes
Q39896760Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination
Q47941525Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients
Q40274683Characterization of the CD8+ T cell responses directed against respiratory syncytial virus during primary and secondary infection in C57BL/6 mice
Q31151209Characterization of the peptide-binding specificity of Mamu-A*11 results in the identification of SIV-derived epitopes and interspecies cross-reactivity
Q40032484Characterizing the Mycobacterium tuberculosis Rv2707 protein and determining its sequences which specifically bind to two human cell lines.
Q37864525Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells.
Q36365784Citrullination only infrequently impacts peptide binding to HLA class II MHC
Q47998083Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution
Q37864193Clearance of Chlamydia pneumoniae infection in H-2 class I human leucocyte antigen-A2.1 monochain transgenic mice
Q33414050Clinical and immunological markers of dengue progression in a study cohort from a hyperendemic area in Malaysia
Q33721633Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method
Q46261095Co-factor-independent phosphoglycerate mutase of Leishmania donovani modulates macrophage signalling and promotes T-cell repertoires bearing epitopes for both MHC-I and MHC-II.
Q39243560Combinatorial chemistry by ant colony optimization.
Q31126784Combinatorial peptide library methods for immunobiology research
Q37700567Combined cytolytic effects of a vaccinia virus encoding a single chain trimer of MHC-I with a Tax-epitope and Tax-specific CTLs on HTLV-I-infected cells in a rat model.
Q34425066Combining computer algorithms with experimental approaches permits the rapid and accurate identification of T cell epitopes from defined antigens
Q33999284Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data.
Q22065493Comparative Genomic Analysis of Chlamydia trachomatis Oculotropic and Genitotropic Strains
Q61709634Comparing the pathogenesis of experimental autoimmune encephalomyelitis in CD4−/− and CD8−/− DBA/1 mice defines qualitative roles of different T cell subsets
Q34256148Comparing the similarity of different groups of bacteria to the human proteome
Q39005162Comparison of experimental fine-mapping to in silico prediction results of HIV-1 epitopes reveals ongoing need for mapping experiments
Q40673830Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides
Q44789283Composition of the HLA-DR-associated human thymus peptidome.
Q27472881Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities
Q36440605Compromised central tolerance of ICA69 induces multiple organ autoimmunity.
Q38915682Computational Resources for MHC Ligand Identification
Q45399910Computational analysis of proteome of H5N1 avian influenza virus to define T cell epitopes with vaccine potential.
Q50933370Computational approaches to identify common subunit vaccine candidates against bacterial meningitis.
Q38885361Computational genomics tools for dissecting tumour-immune cell interactions
Q34687613Computational immunology: The coming of age.
Q35948335Computational methods for prediction of T-cell epitopes--a framework for modelling, testing, and applications
Q35583039Computational tools for the study of allergens
Q26852825Computational vaccinology: an important strategy to discover new potential S. mansoni vaccine candidates
Q34201227Computer aided prediction and identification of potential epitopes in the receptor binding domain (RBD) of spike (S) glycoprotein of MERS-CoV.
Q34312517Computer aided selection of candidate vaccine antigens
Q42638946Computer-assisted analysis of molecular mimicry between human papillomavirus 16 E7 oncoprotein and human protein sequences
Q35041407Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases
Q36499204Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7
Q35927376Conservation analysis of dengue virus T-cell epitope-based vaccine candidates using Peptide block entropy
Q64360303Conserved peptide vaccine candidates containing multiple Ebola nucleoprotein epitopes display interactions with diverse HLA molecules
Q36339503Constitutive and inflammatory immunopeptidome of pancreatic β-cells
Q33363387Contamination of synthetic HuD protein spanning peptide pools with a CMV-encoded peptide
Q37313736Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.
Q57808143Contribution of the plasma and lymph Degradome and Peptidome to the MHC Ligandome
Q42676309Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes
Q37075162Coping with loss of perfection in the MHC class I peptide repertoire
Q35119641Could TCR antagonism explain associations between MHC genes and disease?
Q55342452Cross-sectional analysis of CD8 T cell immunity to human herpesvirus 6B.
Q51072328Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1.
Q27640122Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B
Q31048582Curation of complex, context-dependent immunological data
Q64947848Current progress of immunoinformatics approach harnessed for cellular- and antibody-dependent vaccine design.
Q38953021Current tools for predicting cancer-specific T cell immunity
Q87421678Customized predictions of peptide-MHC binding and T-cell epitopes using EPIMHC
Q40550760Cutting Edge: Predetermined Avidity of Human CD8 T Cells Expanded on Calibrated MHC/Anti-CD28-Coated Microspheres
Q34243434Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen
Q51912898Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2.
Q34712758Cytolytic T lymphocytes from HLA-B8+ donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus
Q34390499Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging
Q36648360Cytotoxic T-cell precursor frequencies to HER-2 (369-377) in patients with HER-2/neu-positive epithelial tumours
Q34353365Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice
Q36591409DDX3Y encodes a class I MHC-restricted H-Y antigen that is expressed in leukemic stem cells
Q35826392DNA fusion gene vaccines against cancer: from the laboratory to the clinic.
Q37885288DNA fusion vaccines enter the clinic.
Q37866631DNA immunization followed by a viral vector booster in a Chlamydia pneumoniae mouse model.
Q36154869DNA prime-adenovirus boost immunization induces a vigorous and multifunctional T-cell response against hepadnaviral proteins in the mouse and woodchuck model
Q57027357DNA prime-protein boost vaccine encoding HLA-A2, -A24 and -DR1 restricted epitopes of CaNA2 against visceral leishmaniasis
Q34127323DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8+ T-cell immune responses
Q40086895Dana-Farber repository for machine learning in immunology
Q38612613Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity.
Q50955695Deciphering complex patterns of class-I HLA-peptide cross-reactivity via hierarchical grouping.
Q61443414DeepSeqPan, a novel deep convolutional neural network model for pan-specific class I HLA-peptide binding affinity prediction
Q35786206Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules
Q78311457Definition of permissible and immunogenic HLA antigens based on epitope analysis of the HLA specific antibodies produced in sensitized patients
Q51036610Definition of supertypes for HLA molecules using clustering of specificity matrices.
Q77068420Definition of the immunogenic HLA epitopes based on an epitope prediction algorithm
Q35939427Dendritic cells loaded with mRNA encoding full-length tumor antigens prime CD4+ and CD8+ T cells in melanoma patients
Q43657065Dendritic cells presenting pyruvate kinase M1/M2 isozyme peptide can induce experimental allergic myositis in BALB/c mice
Q28475576Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy
Q37473978Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma
Q43472318Design and characterization of a chimeric multiepitope construct containing CfaB, heat-stable toxoid, CssA, CssB, and heat-labile toxin subunit B of enterotoxigenic Escherichia coli: a bioinformatic approach.
Q53637625Design and use of conditional MHC class I ligands.
Q33746654Design and utilization of epitope-based databases and predictive tools
Q43093883Design of enhanced agonists through the use of a new virtual screening method: application to peptides that bind class I major histocompatibility complex (MHC) molecules
Q53631492Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.
Q38820109Designing of Epitope-Focused Vaccine by Targeting E6 and E7 Conserved Protein Sequences: An Immuno-Informatics Approach in Human Papillomavirus 58 Isolates
Q35058917Designing of interferon-gamma inducing MHC class-II binders.
Q41874594Designing string-of-beads vaccines with optimal spacers
Q38800011Designing therapeutic cancer vaccines by mimicking viral infections
Q89210618Detection of vasostatin-1-specific CD8(+) T cells in non-obese diabetic mice that contribute to diabetes pathogenesis
Q45888990Determination of specific CD4 and CD8 T cell epitopes after AAV2- and AAV8-hF.IX gene therapy
Q90576547Developing neoantigen-targeted T cell-based treatments for solid tumors
Q36029171Development of Acquired Immunity following Repeated Respiratory Syncytial Virus Infections in Cotton Rats
Q34358851Development of a novel in silico docking simulation model for the fine HIV-1 cytotoxic T lymphocyte epitope mapping
Q37394695Development of a peptide-based vaccine targeting TMPRSS2:ERG fusion-positive prostate cancer
Q44923495Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains.
Q33489506Development, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen
Q38533017Developments in cancer vaccines for hepatocellular carcinoma
Q52005389Differences in maintenance of CD8+ and CD4+ bacteria‐specific effector‐memory T cell populations
Q42592117Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis
Q38960204Differential ion mobility spectrometry coupled to tandem mass spectrometry enables targeted leukemia antigen detection
Q44284826Differential quantitative analysis of MHC ligands by mass spectrometry using stable isotope labeling.
Q37192020Dipeptides promote folding and peptide binding of MHC class I molecules
Q39768969Direct antigen presentation by DC shapes the functional CD8(+) T-cell repertoire against the nuclear self-antigen La-SSB.
Q36689109Direct class I HLA antigen discovery to distinguish virus-infected and cancerous cells
Q30361736Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin
Q51945027Direct prediction of T-cell epitopes using support vector machines with novel sequence encoding schemes.
Q27473483Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide
Q38347244Discovering protective CD8 T cell epitopes--no single immunologic property predicts it!
Q34130833Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries
Q37322142Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection
Q37456000Discovery of naturally processed and HLA-presented class I peptides from vaccinia virus infection using mass spectrometry for vaccine development
Q34093166Discovery of novel cross-protective Rickettsia prowazekii T-cell antigens using a combined reverse vaccinology and in vivo screening approach
Q37276597Discovery of novel targets for multi-epitope vaccines: screening of HIV-1 genomes using association rule mining
Q51991472Discriminating self from nonself with short peptides from large proteomes.
Q36407362Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses
Q39956342Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure
Q38750956Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages
Q36499325Diversity and evolution of the rhoph1/clag multigene family of Plasmodium falciparum
Q33227607Diversity in the acute CD8 T cell response to vaccinia virus in humans
Q34650773Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells
Q36186533Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?
Q37033008Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?
Q51001482Double- and monofunctional CD4⁺ and CD8⁺ T-cell responses to Mycobacterium tuberculosis DosR antigens and peptides in long-term latently infected individuals.
Q34347732Driving forces of proteasome-catalyzed peptide splicing in yeast and humans
Q42797684Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease
Q43031528Dynamics of immature subsets of dendritic cells during antiviral therapy in HLA-A24-positive chronic hepatitis C patients
Q34601454Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak
Q26822893Effects of Peptide on NK cell-mediated MHC I recognition
Q35214407Efficacy of HLA-DRB1∗03:01 and H2E transgenic mouse strains to correlate pathogenic thyroglobulin epitopes for autoimmune thyroiditis.
Q39800428Efficient induction of cytotoxic T lymphocytes specific for severe acute respiratory syndrome (SARS)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a.
Q35083983Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
Q35100809Emerging vaccine informatics
Q26781304Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways
Q39424744Endogenous retrovirus sequences as a novel class of tumor-specific antigens: an example of HERV-H env encoding strong CTL epitopes
Q30479692Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection
Q34047191Enhanced early innate and T cell-mediated responses in subjects immunized with Anthrax Vaccine Adsorbed Plus CPG 7909 (AV7909)
Q40215247Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide
Q45083568Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, alpha-galactosylceramide
Q51990458Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles.
Q36487452Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells
Q33236277EpiJen: a server for multistep T cell epitope prediction
Q39784947EpiToolKit--a web server for computational immunomics
Q34486583EpicCapo: epitope prediction using combined information of amino acid pairwise contact potentials and HLA-peptide contact site information.
Q35827003Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes
Q24802067Epitope definition by proteomic similarity analysis: identification of the linear determinant of the anti-Dsg3 MAb 5H10
Q51894674Epitope landscape in breast and colorectal cancer.
Q36062915Epitope mapping of HSV-1 glycoprotein K (gK) reveals a T cell epitope located within the signal domain of gK
Q36620162Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties
Q40266719Epitopes rationally selected through computational analyses induce T-cell proliferation in mice and are recognized by serum from individuals infected with Schistosoma mansoni.
Q39920161Essential differences in ligand presentation and T cell epitope recognition among HLA molecules of the HLA-B44 supertype
Q40511063Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding Lassa virus nucleoprotein
Q33325636Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research
Q33393949Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research
Q36909127Evidence for positive selection in putative virulence factors within the Paracoccidioides brasiliensis species complex
Q33290217Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1
Q50317337Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.
Q40809435Ex vivo generation of human cytomegalovirus-specific cytotoxic T cells by peptide-pulsed dendritic cells
Q34975513Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.
Q47617870Examination of possible structural constraints of MHC-binding peptides by assessment of their native structure within their source proteins.
Q35262045Examining variable domain orientations in antigen receptors gives insight into TCR-like antibody design
Q54648290Expansion of CD4 T cells expressing a highly restricted TCR structure specific for a single parasite epitope correlates with high pathology in murine schistosomiasis.
Q33850655Expansion of interferon-gamma-producing multifunctional CD4+ T-cells and dysfunctional CD8+ T-cells by glypican-3 peptide library in hepatocellular carcinoma patients
Q53647622Experimental myositis inducible with transfer of dendritic cells presenting a skeletal muscle C protein-derived CD8 epitope peptide.
Q38913724Exploration of peptides bound to MHC class I molecules in melanoma
Q38752281Exploration of the BF2*15 major histocompatibility complex class I binding motif and identification of cytotoxic T lymphocyte epitopes from the H5N1 influenza virus nucleoprotein in chickens
Q40512928Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo.
Q45929502Exploring the MHC-peptide matrix of central tolerance in the human thymus.
Q40821867Exploring the unbinding of Leishmania (L.) amazonensis CPB derived-epitopes from H2 MHC class I proteins
Q33269889Expression library immunization confers partial protection against Chlamydia muridarum genital infection.
Q34777218Expression of cutaneous lymphocyte-associated antigen by CD8(+) T cells specific for a skin-tropic virus
Q37066721Extensive HLA class I allele promiscuity among viral CTL epitopes
Q24548447FIMM, a database of functional molecular immunology: update 2002
Q33478350FRED--a framework for T-cell epitope detection
Q87789748FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity
Q37754754Factors influencing immunodominance hierarchies in TCD8+ -mediated antiviral responses
Q33377255Flanking p10 contribution and sequence bias in matrix based epitope prediction: revisiting the assumption of independent binding pockets
Q36874759Fowlpox-based survivin vaccination for malignant mesothelioma therapy
Q40801080Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens
Q61759673Functional expression of a bovine major histocompatibility complex class I gene in transgenic mice
Q33482103Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation
Q49594989Fundamentals and Methods for T- and B-Cell Epitope Prediction.
Q34023265GM-CSF production allows the identification of immunoprevalent antigens recognized by human CD4+ T cells following smallpox vaccination
Q34221724GPS-MBA: computational analysis of MHC class II epitopes in type 1 diabetes
Q47601200Gapped sequence alignment using artificial neural networks: application to the MHC class I system.
Q52026288Gender differences in HLA phenotype frequencies found in German patients with generalized aggressive periodontitis and chronic periodontitis.
Q50113046Gene delivery by attenuated Salmonella typhimurium: comparing the efficacy of helper versus cytotoxic T cell priming in tumor vaccination.
Q33691683Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma
Q24815448Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method
Q38942201Generation of cytotoxic T lymphocytes specific for native or modified peptides derived from the epidermal growth factor receptor pathway substrate 8 antigen
Q57221639Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
Q36028231Genetic aspects of immune-mediated adverse drug effects
Q33814247Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma
Q28748331Genetic linkage of autologous T cell epitopes in a chimeric recombinant construct improves anti-parasite and anti-disease protective effect of a malaria vaccine candidate
Q51759998Genome-based approaches to develop epitope-driven subunit vaccines against pathogens of infective endocarditis.
Q35648255Genome-derived vaccines
Q37398991Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases
Q35030976Genomics-based identification of self-ligands with T cell receptor-specific biological activity
Q39740215Getting peptide vaccines to work: just a matter of quality control?
Q42416375Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by major histocompatibility complex class I in vitro and in woodchucks
Q45730978Glycoprotein B from strain 17 of herpes simplex virus type I contains an invariant chain homologous sequence that binds to MHC class II molecules
Q47317031GradDock: Rapid Simulation and Tailored Ranking Functions for Peptide-MHC Class I Docking.
Q33857800Graft-versus-leukemia antigen CML66 elicits coordinated B-cell and T-cell immunity after donor lymphocyte infusion
Q33754985H-2 Kd-restricted hepatitis B virus-derived epitope whose specific CD8+ T lymphocytes can produce gamma interferon without cytotoxicity
Q51987940HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.
Q37028039HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
Q24299045HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasis
Q37414385HLA class I alleles are associated with peptide-binding repertoires of different size, affinity, and immunogenicity
Q38819387HLA class I binding prediction via convolutional neural networks
Q27324007HLA class I molecular variation and peptide-binding properties suggest a model of joint divergent asymmetric selection
Q33315730HLA class I supertypes: a revised and updated classification
Q36194073HLA class I transgenic mice: development, utilisation and improvement
Q90425771HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells
Q34655698HLA class II peptide-binding and autoimmunity
Q38148779HLA ligandome tumor antigen discovery for personalized vaccine approach
Q37116031HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase
Q42598828HLA-A2-restricted T-cell epitopes specific for prostatic acid phosphatase
Q47835567HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses
Q38560231HLA-B polymorphisms and intracellular assembly modes.
Q33911914HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load
Q33918894HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.
Q34341384HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function
Q36303660HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives
Q36737531HLA-DR: molecular insights and vaccine design
Q38217357HLA-binding properties of tumor neoepitopes in humans
Q39788447HLaffy: estimating peptide affinities for Class-1 HLA molecules by learning position-specific pair potentials
Q39076137HPV16 E5 peptide vaccine in treatment of cervical cancer in vitro and in vivo
Q36791906HapMap SNP Scanner: an online program to mine SNPs responsible for cell phenotype
Q40674982Harnessing the cellular immune system to the gene-prediction cart
Q37735121Hepatitis B splice-generated protein antibodies in Syrian chronic hepatitis B patients: incidence and significance
Q35857548Hepatitis B virus splice-generated protein induces T-cell responses in HLA-transgenic mice and hepatitis B virus-infected patients
Q37174520Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection
Q37275906Heterologous vaccination against human tuberculosis modulates antigen-specific CD4+ T-cell function
Q52005186Heterozygote advantage fails to explain the high degree of polymorphism of the MHC.
Q39301397High immunogenicity of the human leukocyte antigen peptidomes of melanoma tumor cells
Q33628719High throughput T epitope mapping and vaccine development
Q93051749High-Throughput Stability Screening of Neoantigen/HLA Complexes Improves Immunogenicity Predictions
Q36972511High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes
Q33995557High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations
Q43483087Highly conserved pattern of recognition of influenza A wild-type and variant CD8+ CTL epitopes in HLA-A2+ humans and transgenic HLA-A2+/H2 class I-deficient mice
Q33322206Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes
Q26750788How frequently are predicted peptides actually recognized by CD8 cells?
Q33293891Human CD4(+) memory T-lymphocyte responses to SARS coronavirus infection
Q33302672Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection
Q33321888Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery.
Q41487863Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires
Q28251022Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response
Q24289630Human T cell responses to Japanese encephalitis virus in health and disease
Q33245126Human antibody responses of patients living in endemic areas for schistosomiasis to the tegumental protein Sm29 identified through genomic studies.
Q44315577Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients.
Q39742082Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice
Q57445880Human population-based identification of CD4+ T-cell peptide epitope determinants
Q41839973Human self-protein CD8+ T-cell epitopes are both positively and negatively selected
Q51820107Humanization of Predicted T-Cell Epitopes Reduces the Immunogenicity of Chimeric Antibodies: New Evidence Supporting a Simple Method
Q42847212IDR knowledge base for primary immunodeficiencies
Q38963058Identification and characterisation of peptide binding motifs of six autoimmune disease-associated human leukocyte antigen-class I molecules including HLA-B*39:06.
Q34509541Identification and characterization of H-2d restricted CD4+ T cell epitopes on Lpp20 of Helicobacter pylori
Q35857723Identification and characterization of dominant helper T-cell epitopes in the nucleocapsid protein of severe acute respiratory syndrome coronavirus
Q28710385Identification and characterization of human leukocyte antigen class I ligands in renal cell carcinoma cells
Q39865703Identification and characterization of survivin-derived H-2Kb-restricted CTL epitopes
Q30418879Identification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.
Q38462400Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients
Q90628298Identification of Antigenic Targets
Q45362381Identification of B- and T-cell epitopes from glycoprotein B of herpes simplex virus 2 and evaluation of their immunogenicity and protection efficacy
Q40403892Identification of B- and T-cell epitopes within the fibronectin-binding domain of the SfbI protein of Streptococcus pyogenes
Q64054729Identification of CD4 and H-2K-restricted cytotoxic T lymphocyte epitopes on the human herpesvirus 6B glycoprotein Q1 protein
Q35078281Identification of CD8+ cytotoxic T lymphocyte epitopes from porcine reproductive and respiratory syndrome virus matrix protein in BALB/c mice
Q34125106Identification of Chlamydia pneumoniae-derived mouse CD8 epitopes
Q36367674Identification of Conserved Peptides Comprising Multiple T Cell Epitopes of Matrix 1 Protein in H1N1 Influenza Virus
Q35832185Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma
Q92206244Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models
Q37336046Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+ HCMV-specific cytotoxic T lymphocytes
Q51066151Identification of HLA-A2-restricted immunogenic peptides derived from a xenogenic porcine major histocompatibility complex.
Q35210224Identification of HLA-B27-restricted peptides in reactive arthritis and other spondyloarthropathies: computer algorithms and fluorescent activated cell sorting analysis as tools for hunting of HLA-B27-restricted chlamydial and autologous crossreacti
Q37707523Identification of HLA‑A*1101‑restricted cytotoxic T lymphocyte epitopes derived from epidermal growth factor pathway substrate number 8.
Q35867348Identification of Immunodominant Responses to the Plasmodium falciparum Antigens PfUIS3, PfLSA1 and PfLSAP2 in Multiple Strains of Mice
Q28550337Identification of Immunoreactive Leishmania infantum Protein Antigens to Asymptomatic Dog Sera through Combined Immunoproteomics and Bioinformatics Analysis
Q38909633Identification of Mycobacterium tuberculosis PPE68-specific HLA-A*0201-restricted epitopes for tuberculosis diagnosis
Q35411077Identification of NY-BR-1-specific CD4(+) T cell epitopes using HLA-transgenic mice
Q35549821Identification of Novel Potential Vaccine Candidates against Tuberculosis Based on Reverse Vaccinology
Q36610286Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy
Q30717088Identification of T helper cell-recognized epitopes in the chitinase of the filarial nematode Onchocerca volvulus
Q36870592Identification of T-cell epitopes for cancer immunotherapy
Q59806946Identification of a First Human Norovirus CD8 T Cell Epitope Restricted to HLA-A0201 Allele
Q50054503Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen.
Q57285391Identification of a Shared Cytochrome p4502E1 Epitope Found in Anesthetic Drug-Induced and Viral Hepatitis
Q24649346Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes
Q34508082Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors
Q40585877Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein
Q40439479Identification of a new HLA-A*0201-restricted CD8+ T cell epitope from hepatocellular carcinoma-associated antigen HCA587.
Q30951751Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV.
Q45728526Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein
Q42153821Identification of a novel p190-derived breakpoint Peptide suitable for Peptide vaccine therapeutic approach in ph+ acute lymphoblastic leukemia patients.
Q39727327Identification of a novel peptide derived from the M-phase phosphoprotein 11 (MPP11) leukemic antigen recognized by human CD8+ cytotoxic T lymphocytes.
Q24673417Identification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigens
Q40417298Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus
Q24645122Identification of an HLA-A*0201-restricted T-cell epitope derived from the prostate cancer-associated protein prostein
Q33315752Identification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening
Q52349546Identification of an HLA-A2-restricted CD147 epitope that can induce specific CTL cytotoxicity against drug resistant MCF-7/Adr cells.
Q39990744Identification of an epitope derived from CML66, a novel tumor-associated antigen expressed broadly in human leukemia, recognized by human leukocyte antigen-A*2402-restricted cytotoxic T lymphocytes
Q33219527Identification of an immunogenic EWS-FLI1-derived HLA-DR-restricted T helper cell epitope
Q36399462Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames
Q34520629Identification of early secretory antigen target-6 epitopes for the immunodiagnosis of active tuberculosis.
Q37545011Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children
Q52043734Identification of known and novel immunogenic T-cell epitopes from tumor antigens recognized by peripheral blood T cells from patients responding to IL-2-based treatment.
Q40436586Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein
Q31080718Identification of murine H2-Dd- and H2-Ab-restricted T-cell epitopes on a novel protective antigen, MPT51, of Mycobacterium tuberculosis
Q40540049Identification of murine T-cell epitopes in Ebola virus nucleoprotein
Q44486249Identification of murine T-cell epitopes on low-molecular-mass secretory proteins (CFP11, CFP17, and TB18.5) of Mycobacterium tuberculosis
Q43461527Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction.
Q40884483Identification of novel CD8+ T cell epitopes in human herpesvirus 6B U11 and U90.
Q39224992Identification of novel HLA-A 0201-restricted cytotoxic T lymphocyte epitopes from Zinc Transporter 8.
Q36725757Identification of novel IGRP epitopes targeted in type 1 diabetes patients.
Q39539865Identification of promiscuous HLA-DR-restricted CD4⁺ T-cell epitopes on the cancer-testis antigen HCA587.
Q42218961Identification of promiscuous HPV16-derived T helper cell epitopes for therapeutic HPV vaccine design
Q34243390Identification of prostatic acid phosphatase (PAP) specific HLA-DR1-restricted T-cell epitopes
Q62555865Identification of synthetic vaccine candidates against SARS CoV infection
Q24679680Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.
Q39607014Identification of the immunodominant H-2K(k)-restricted cytotoxic T-cell epitope in the Borna disease virus nucleoprotein
Q45887812Identification of the immunodominant cytotoxic T-cell epitope of human alpha-1 antitrypsin.
Q45882310Identification of the murine firefly luciferase-specific CD8 T-cell epitopes.
Q35604748Identification of three novel CTL epitopes within nucleocapsid protein of Hantaan virus
Q34718188Identification of tumour-associated T-cell epitopes for vaccine development
Q92611787Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy
Q34467405Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.
Q43102522Identification of varicella-zoster virus-specific CD8 T cells in patients after T-cell-depleted allogeneic stem cell transplantation
Q50057949Immune monitoring and TCR sequencing of CD4 T cells in a long term responsive patient with metastasized pancreatic ductal carcinoma treated with individualized, neoepitope-derived multipeptide vaccines: a case report.
Q40599136Immune recognition of a human renal cancer antigen through post-translational protein splicing.
Q36296166Immune surveillance of intracellular pathogens via autophagy
Q81538924Immunization with hybrid recombinant Mycobacterium tuberculosis H37Rv proteins increases the TH1 cytokine response in mice following a pulmonary instillation of irradiated mycobacteria
Q30250980ImmunoNodes - graphical development of complex immunoinformatics workflows
Q52365761Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1.
Q37158031Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.
Q91636268Immunogenicity and Immune Silence in Human Cancer
Q37046880Immunogenicity of HLA-DR1 Restricted Peptides Derived from Leishmania major gp63 Using FVB/N-DR1 Transgenic Mouse Model
Q36509894Immunogenicity of MHC Class I Peptides Derived from Leishmania mexicana Gp63 in HLA-A2.1 Transgenic (HHDII) and BALB/C Mouse Models
Q34546149Immunogenicity of Multi-Epitope DNA and Peptide Vaccine Candidates Based on Core, E2, NS3 and NS5B HCV Epitopes in BALB/c Mice
Q44842813Immunogenicity of eight Mycobacterium avium subsp. paratuberculosis specific antigens in DNA vaccinated and Map infected mice
Q42217677Immunogenicity of recombinant human bocavirus-1,2 VP2 gene virus-like particles in mice
Q49168236Immunogenicity screening in protein drug development.
Q57556550Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies
Q51534488Immunoglobulin light chain, Blimp-1 and cytochrome P4501B1 peptides as potential vaccines for AL amyloidosis.
Q36304147Immunoinformatics and epitope prediction in the age of genomic medicine
Q21145682Immunoinformatics comes of age
Q37781086Immunoinformatics: an integrated scenario
Q28241898Immunoinformatics: current trends and future directions
Q37545001Immunological characterization of a modified vaccinia virus Ankara vector expressing the human papillomavirus 16 E1 protein
Q40369476Immunological cross-reactivity against a drug mutated HIV-1 protease epitope after DNA multi-CTL epitope construct immunization.
Q50979402Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes.
Q38728603Immunomics: a 21st century approach to vaccine development for complex pathogens
Q66679236Immunoproteomic analysis of a Chikungunya poxvirus-based vaccine reveals high HLA class II immunoprevalence
Q28238379Immunoproteomics: Mass spectrometry-based methods to study the targets of the immune response
Q36133140Immunotherapy for pancreatic cancer - science driving clinical progress
Q56927415Impact of Leishmania donovani infection on the HLA I self peptide repertoire of human macrophages
Q37586592Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment
Q45398545Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus
Q33370669Improving peptide-MHC class I binding prediction for unbalanced datasets
Q42910320In Silico Design and Analysis of TGFαL3-SEB Fusion Protein as "a New Antitumor Agent" Candidate by Ligand-Targeted Superantigens Technique
Q36985387In Silico Design of a Chimeric Protein Containing Antigenic Fragments of Helicobacter pylori; A Bioinformatic Approach.
Q42934914In silico CD4+ T-cell epitope prediction and HLA distribution analysis for the potential proteins of Neisseria meningitidis Serogroup B--a clue for vaccine development
Q100415799In silico analysis and in vivo assessment of a novel epitope-based vaccine candidate against uropathogenic Escherichia coli
Q35198753In silico analysis of six known Leishmania major antigens and in vitro evaluation of specific epitopes eliciting HLA-A2 restricted CD8 T cell response.
Q55490730In silico and ex vivo approaches indicate immune pressure on capsid and non-capsid regions of coxsackie B viruses in the human system.
Q36088477In silico characterization of immunogenic epitopes presented by HLA-Cw*0401
Q90592477In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection
Q37858087In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB.
Q37610312In silico methods for predicting T-cell epitopes: Dr Jekyll or Mr Hyde?
Q48008312In silico prediction of Leishmania major-specific CD8+ epitopes
Q90911275In silico/In vivo analysis of high-risk papillomavirus L1 and L2 conserved sequences for development of cross-subtype prophylactic vaccine
Q84002630In vitro and in vivo identification of a novel cytotoxic T lymphocyte epitope from Rv3425 of Mycobacterium tuberculosis
Q28541967In vitro and in vivo studies for assessing the immune response and protection-inducing ability conferred by Fasciola hepatica-derived synthetic peptides containing B- and T-cell epitopes
Q59356991In vivo and in vitro immunogenicity of novel MHC class I presented epitopes to confer protective immunity against chronic HTLV-1 infection
Q47550608In-depth phylodynamics, evolutionary analysis and in silico predictions of universal epitopes of Influenza A subtypes and Influenza B viruses
Q77475273Individuation of monoclonal anti-HPV16 E7 antibody linear peptide epitope by computational biology
Q36509692Induction of CD4+ Th1 lymphocytes that recognize known and novel class II MHC restricted epitopes from the melanoma antigen gp100 by stimulation with recombinant protein
Q40730694Induction of Specific CD8 T Cells against Intracellular Bacteria by CD8 T-Cell-Oriented Immunization Approaches
Q31076623Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.
Q33307523Induction of human immunodeficiency virus (HIV-1) envelope specific cell-mediated immunity by a non-homologous synthetic peptide
Q36896712Innate and adaptive immunity through autophagy
Q34056087Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.
Q37748492Innovative bioinformatic approaches for developing peptide-based vaccines against hypervariable viruses
Q37851048Insights into MHC class I antigen processing gained from large-scale analysis of class I ligands
Q42689269Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.
Q34429970Integrated modeling of the major events in the MHC class I antigen processing pathway
Q31111568Integrating epitope data into the emerging web of biomedical knowledge resources
Q34788108Integrating peptides' sequence and energy of contact residues information improves prediction of peptide and HLA-I binding with unknown alleles
Q37859218Interaction of allergens, major histocompatibility complex molecules, and T cell receptors: a 'ménage à trois' that opens new avenues for therapeutic intervention in type I allergy
Q34189720Interaction pattern of Arg 62 in the A-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes
Q30251957Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review.
Q34214158Interferon-gamma inducible exchanges of 20S proteasome active site subunits: why?
Q95491344Introduction
Q44142652Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells
Q44220785Is fungal foot infection the initiating and maintaining cause of knee osteoarthritis?
Q37404522Is the risk of multiple sclerosis related to the 'biography' of the immune system?
Q91971816Key Features Relevant to Select Antigens and TCR From the MHC-Mismatched Repertoire to Treat Cancer
Q37434480LAPTM4B-35 protein is a weak tumor-associated antigen candidate
Q40429655Lack of effective T-lymphocyte response to the PAX3/FKHR translocation area in alveolar rhabdomyosarcoma
Q45383350Lack of immune responses against multiple sclerosis-associated retrovirus/human endogenous retrovirus W in patients with multiple sclerosis
Q24288783Large scale characterization of the LC13 TCR and HLA-B8 structural landscape in reaction to 172 altered peptide ligands: a molecular dynamics simulation study
Q73401896Large-scale analysis of HLA peptides presented by HLA-Cw4
Q59134452Large-scale computational identification of HIV T-cell epitopes
Q40603434Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.
Q33304572Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction
Q27472584Lassa fever virus peptides predicted by computational analysis induce epitope-specific cytotoxic-T-lymphocyte responses in HLA-A2.1 transgenic mice
Q44252110Lentiviral vector followed by protein immunisation breaks tolerance against the self-antigen Her1 and results in lung cancer immunotherapy
Q40156180Lentiviral vectors encoding HIV-1 polyepitopes induce broad CTL responses in vivo.
Q33931811Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells
Q50447093Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens.
Q90101976Ligandomes obtained from different HLA-class II-molecules are homologous for N- and C-terminal residues outside the peptide-binding cleft
Q51075893Liposomes containing NY‑ESO‑1/tetanus toxoid and adjuvant peptides targeted to human dendritic cells via the Fc receptor for cancer vaccines.
Q36307488Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice
Q34789311Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.
Q57325915Long-peptide vaccination with driver gene mutations in p53 and Kras induces cancer mutation-specific effector as well as regulatory T cell responses
Q42619783Long-term T cell memory to human leucocyte antigen-A2 supertype epitopes in humans vaccinated against smallpox
Q48091147Longevity of antibody and T-cell responses against outer membrane antigens of Orientia tsutsugamushi in scrub typhus patients.
Q37738467Low level of HIV-1 evolution after transmission from mother to child
Q37636670Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed against tumor-associated antigens
Q33757923MHC Class I Presented T Cell Epitopes as Potential Antigens for Therapeutic Vaccine against HBV Chronic Infection
Q36088285MHC Class II Binding Prediction by Molecular Docking
Q46459379MHC Class II Risk Alleles and Amino Acid Residues in Idiopathic Membranous Nephropathy
Q40746040MHC I stabilizing potential of computer-designed octapeptides.
Q36266437MHC class I alleles and their exploration of the antigen-processing machinery
Q52838605MHC class I molecules exploit the low G+C content of pathogen genomes for enhanced presentation.
Q37452154MHC class I-associated peptides derive from selective regions of the human genome
Q36381178MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response
Q30388353MHC class II epitope predictive algorithms.
Q41944422MHC motif viewer
Q37790648MHC presentation via autophagy and how viruses escape from it.
Q51938042MHC-BPS: MHC-binder prediction server for identifying peptides of flexible lengths from sequence-derived physicochemical properties.
Q42629047MHC-I prediction using a combination of T cell epitopes and MHC-I binding peptides
Q37696988MHC-based detection of antigen-specific CD8+ T cell responses.
Q35911151MHC-bound antigens and proteomics for novel target discovery.
Q33432313MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes
Q39804098MHCPred: A server for quantitative prediction of peptide-MHC binding.
Q90552077MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics
Q35914254MODPROPEP: a program for knowledge-based modeling of protein-peptide complexes
Q24813031MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides
Q91671018Machine Learning for Cancer Immunotherapies Based on Epitope Recognition by T Cell Receptors
Q26767472Major Histocompatibility Complex and Malaria: Focus on Plasmodium vivax Infection
Q37762296Major histocompatibility complex class I binding predictions as a tool in epitope discovery.
Q36194241Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1(+) leukemias
Q34645213Mapping sites of positive selection and amino acid diversification in the HIV genome: an alternative approach to vaccine design?
Q64910188Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation.
Q57178228Mapping the tumour human leukocyte antigen (HLA) ligandome by mass spectrometry
Q30002365Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation
Q39474621Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells
Q36986531Mass spectrometry and peptide-based vaccine development
Q92052807Mass spectrometry-based identification of MHC-bound peptides for immunopeptidomics
Q24555754Mate choice decisions of stickleback females predictably modified by MHC peptide ligands
Q39849181Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture
Q35050403Mechanisms of MHC class I-restricted antigen presentation
Q47191093Membranal and blood-soluble HLA class II peptidome analyses using data-dependent and independent acquisition
Q36399737Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients
Q33957612MetaMHC: a meta approach to predict peptides binding to MHC molecules.
Q51554310Metadherin peptides containing CD4(+) and CD8(+) T cell epitopes as a therapeutic vaccine candidate against cancer.
Q33271867Mimotope vaccines for cancer immunotherapy
Q30621114Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Q48372980Modeling the adaptive immune system: predictions and simulations.
Q43102307Modeling the repertoire of true tumor-specific MHC I epitopes in a human tumor
Q36519420Modeling the structure of bound peptide ligands to major histocompatibility complex
Q33635226Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition
Q36690145Molecular characterization of HTLV-1 gp46 glycoprotein from health carriers and HAM/TSP infected individuals
Q27469459Molecular epidemiology of hepatitis C virus genotype 4 isolates in Egypt and analysis of the variability of envelope proteins E1 and E2 in patients with chronic hepatitis
Q30589557Molecular immunology databases and data repositories.
Q40953830Molecular mimicry of MAGE-A6 and Mycoplasma penetrans HF-2 epitopes in the induction of antitumor CD8(+) T-cell responses
Q43909373Molecular modeling of class I and II alleles of the major histocompatibility complex in Salmo salar
Q34737266Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells
Q39886235Monitoring macroautophagy by major histocompatibility complex class II presentation of targeted antigens
Q42673280Monoclonal and polyclonal humoral immune response to EC HER-2/NEU peptides with low similarity to the host's proteome
Q36808693More than one reason to rethink the use of peptides in vaccine design
Q34416487Mosaic organization and heterogeneity in frequency of allelic recombination of the Plasmodium vivax merozoite surface protein-1 locus
Q33712291Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys
Q64079285Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma
Q33702755MultiRTA: a simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Q31022597Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma
Q64097789Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes
Q37547268Multipeptide vaccination in cancer patients.
Q34801834Multiple proteases process viral antigens for presentation by MHC class I molecules to CD8(+) T lymphocytes
Q36032150Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor
Q24294775Multiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cells
Q42983683Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51.
Q34122073Multiple, non-conserved, internal viral ligands naturally presented by HLA-B27 in human respiratory syncytial virus-infected cells
Q43560379Mutation of Cys-67 alters the thermodynamic stability of the human leukocyte antigen HLA0-B*2705.
Q34734850Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model
Q64074701Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8 T Cells and Evolve at the Population Level
Q35097333Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination
Q33504888NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction
Q28743225NNAlign: a web-based prediction method allowing non-expert end-user discovery of sequence motifs in quantitative peptide data
Q36406293NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination
Q36637651NY-ESO-1 immunotherapy for multiple myeloma
Q34388367NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses
Q36760435Natural HLA-B*2705 protein ligands with glutamine as anchor motif: implications for HLA-B27 association with spondyloarthropathy.
Q35575931Natural selection for rash-forming genotypes of the varicella-zoster vaccine virus detected within immunized human hosts
Q64087357Naturally presented HLA class I-restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes
Q57209274Naturally processed and HLA-B8-presented HPV16 E7 epitope recognized by T cells from patients with cervical cancer
Q88716389Nature of tumour rejection antigens in ovarian cancer
Q40211477Need for tripeptidyl-peptidase II in major histocompatibility complex class I viral antigen processing when proteasomes are detrimental
Q92137757Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors
Q34194564Neonatal and maternal immunological responses to conserved epitopes within the DBL-gamma3 chondroitin sulfate A-binding domain of Plasmodium falciparum erythrocyte membrane protein 1.
Q33873269NetCTLpan: pan-specific MHC class I pathway epitope predictions
Q36749382NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11
Q34366463NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure.
Q35869130NetMHCpan, a method for MHC class I binding prediction beyond humans
Q28469279NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence
Q36742441NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets
Q47827615NetMHCstab - predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery.
Q51083423NetTepi: an integrated method for the prediction of T cell epitopes.
Q47693913Neural models for predicting viral vaccine targets
Q48519025Nomenclature and Serology of HLA Class I and Class II Alleles.
Q37611838Noncanonical expression of a murine cytomegalovirus early protein CD8 T-cell epitope as an immediate early epitope based on transcription from an upstream gene.
Q35728590Noncanonical peptides in complex with MHC class I.
Q40702974Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells
Q47556915Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/Kb Transgenic Mice May Associate with the Severity of Hemorrhagic Fever with Renal Syndrome
Q27664523Novel Immunodominant Peptide Presentation Strategy: a Featured HLA-A*2402-Restricted Cytotoxic T-Lymphocyte Epitope Stabilized by Intrachain Hydrogen Bonds from Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein
Q57011833Novel Machine Learning Methods for MHC Class I Binding Prediction
Q38168900Novel approaches in polyepitope T-cell vaccine development against HIV-1.
Q34401747Novel biochemistry: post-translational protein splicing and other lessons from the school of antigen processing
Q41963641Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response.
Q36962838Novel immunogenic HLA-A*0201-restricted epidermal growth factor receptor-specific T-cell epitope in head and neck cancer patients
Q38789472Novel in silico tools for designing peptide-based subunit vaccines and immunotherapeutics
Q33195013Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin
Q42326379Nuclear export signal and immunodominant CD8+ T cell epitope in influenza A virus matrix protein 1
Q33965222Nucleophosmin is recognized by a cytotoxic T cell line derived from a rectal carcinoma patient.
Q51543580OETMAP: a new feature encoding scheme for MHC class I binding prediction.
Q27005991Ontology-supported research on vaccine efficacy, safety and integrative biological networks
Q41981083OptiTope--a web server for the selection of an optimal set of peptides for epitope-based vaccines.
Q34558230Optimal epitope composition after antigen screening using a live bacterial delivery vector: application to TRP-2.
Q33551448Optimization algorithms for functional deimmunization of therapeutic proteins
Q89097115Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models
Q37239554Optimizing Immunization Strategies for the Induction of Antigen-Specific CD4 and CD8 T Cell Responses for Protection against Intracellular Parasites.
Q37716789Ovine and murine T cell epitopes from the non-structural protein 1 (NS1) of bluetongue virus serotype 8 (BTV-8) are shared among viral serotypes
Q43267507Oxidative stress can alter the antigenicity of immunodominant peptides
Q64882611PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.
Q34074865POPISK: T-cell reactivity prediction using support vector machines and string kernels
Q24813312PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse.
Q31111090PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity
Q51926468PREDNOD, a prediction server for peptide binding to the H-2g7 haplotype of the non-obese diabetic mouse.
Q37090212Pan-specific MHC class I predictors: a benchmark of HLA class I pan-specific prediction methods
Q36633085Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes
Q37719552Patented cancer vaccines: the promising leads
Q30444431PepBank--a database of peptides based on sequence text mining and public peptide data sources
Q33934654PeptX: using genetic algorithms to optimize peptides for MHC binding
Q33751936Peptide binding predictions for HLA DR, DP and DQ molecules
Q37171413Peptide epitope identification for tumor-reactive CD4 T cells
Q31097631Peptide libraries for T cell epitope screening and characterization
Q36007167Peptide vaccine given with a Toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors
Q30992372Peptide vaccines and peptide libraries
Q38293525Peptide-based vaccination and induction of CD8+ T-cell responses against tumor antigens in breast cancer
Q38123488Peptide-based vaccinology: experimental and computational approaches to target hypervariable viruses through the fine characterization of protective epitopes recognized by monoclonal antibodies and the identification of T-cell-activating peptides
Q30252926Peptide-binding motifs of two common equine class I MHC molecules in Thoroughbred horses
Q42545343Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex.
Q39967522Peptides derived from the Mycobacterium tuberculosis Rv1490 surface protein implicated in inhibition of epithelial cell entry: potential vaccine candidates?
Q37360659Peptides presented in vivo by HLA-DR in thyroid autoimmunity.
Q37844539Peptidomimetics: modifying peptides in the pursuit of better vaccines
Q49798727Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes.
Q59136533Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment
Q64236704Perspective: The promises of a holistic view of proteins-impact on antibody engineering and drug discovery
Q42098721Phase-dependent immune evasion of herpesviruses
Q35865440Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations
Q34982611Pivotal role of antibody and subsidiary contribution of CD8+ T cells to recovery from infection in a murine model of Japanese encephalitis
Q34023384Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1
Q58756533Plasmodium vivax Pv12 B-cell epitopes and HLA-DRβ1*-dependent T-cell epitopes in vitro antigenicity
Q99551753Point mutation screening of tumor neoantigens and peptide-induced specific cytotoxic T lymphocytes using The Cancer Genome Atlas database
Q51706853Polyomavirus BK-specific CD8+ T cell responses in patients after allogeneic stem cell transplant.
Q34235351PolysacDB: a database of microbial polysaccharide antigens and their antibodies
Q26752532Post-Genomics and Vaccine Improvement for Leishmania
Q59599346Postgenomic Approaches and Bioinformatics Tools to Advance the Development of Vaccines against Bacteria of the Complex
Q45868986Pre-clinical evaluation of a CEA DNA prime/protein boost vaccination strategy against colorectal cancer
Q49668436Preclinical and clinical development of neoantigen vaccines.
Q40259551Predicted peptides from non-structural proteins of porcine reproductive and respiratory syndrome virus are able to induce IFN-γ and IL-10.
Q33263601Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Q34384277Predicting HLA class I non-permissive amino acid residues substitutions
Q33531925Predicting MHC class I epitopes in large datasets
Q33608371Predicting alloreactivity in transplantation
Q33306761Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms
Q43783758Prediction and characterization of helper T-cell epitopes from pneumococcal surface adhesin A.
Q34321340Prediction and identification of T cell epitopes in the H5N1 influenza virus nucleoprotein in chicken
Q36138983Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins
Q40704435Prediction and preliminary screening of HLA-A*0201-restricted epitope peptides of human GPC3.
Q58707987Prediction of Antimicrobial Potential of a Chemically Modified Peptide From Its Tertiary Structure
Q35532615Prediction of CD8+ Epitopes in Leishmania braziliensis Proteins Using EPIBOT: In Silico Search and In Vivo Validation
Q51442203Prediction of HLA class I-restricted T-cell epitopes of islet autoantigen combined with binding and dissociation assays.
Q42954755Prediction of HLA-A2-restricted CTL epitope specific to HCC by SYFPEITHI combined with polynomial method
Q41807238Prediction of MHC binding peptide using Gibbs motif sampler, weight matrix and artificial neural network
Q36274623Prediction of MHC class I binding peptides by a query learning algorithm based on hidden markov models
Q42066174Prediction of MHC class I binding peptides using probability distribution functions.
Q52034713Prediction of MHC class I binding peptides using profile motifs.
Q24806545Prediction of MHC class I binding peptides, using SVMHC
Q33289831Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method
Q25257552Prediction of MHC class II binding peptides based on an iterative learning model
Q42738481Prediction of cellular immune responses against CFTR in patients with cystic fibrosis after gene therapy.
Q37806810Prediction of epitopes using neural network based methods
Q37462980Prediction of functional class of proteins and peptides irrespective of sequence homology by support vector machines
Q39605619Prediction of promiscuous peptides that bind HLA class I molecules
Q43976304Prediction of proteasome cleavage motifs by neural networks
Q33525382Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Q35813585Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy?
Q40467039Predictor for the effect of amino acid composition on CD4+ T cell epitopes preprocessing.
Q42220503Preliminary exploration of HLA-A 1101-restricted human cytomegalovirus glycoprotein B-specific CD8⁺ T cells in allogeneic stem-cell transplant recipients
Q38951047Present Yourself! By MHC Class I and MHC Class II Molecules
Q34743762Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion
Q36978876Prime/boost immunization with DNA and adenoviral vectors protects from hepatitis D virus (HDV) infection after simultaneous infection with HDV and woodchuck hepatitis virus.
Q64226743Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression
Q38306558Processing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes
Q98771735Progress in Neoantigen Targeted Cancer Immunotherapies
Q27685375Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides
Q35034097Properties of MHC class I presented peptides that enhance immunogenicity
Q78434026Prostate stem cell antigen: Identification of immunogenic peptides and assessment of reactive CD8+ T cells in prostate cancer patients
Q36867296Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model
Q53354360Proteasomes in immune cells: more than peptide producers?
Q33727055Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.
Q43962544Proteome-based epitopic peptide scanning along PSA.
Q24798732Proteomics in Vaccinology and Immunobiology: An Informatics Perspective of the Immunone
Q35056736Proximity ligation assay evaluates IDH1R132H presentation in gliomas
Q35077155Quantitative constraints on the scope of negative selection
Q40548223Quantitative online prediction of peptide binding to the major histocompatibility complex
Q33316579Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries
Q30477638Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models
Q33349439Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan
Q58698657RNA editing derived epitopes function as cancer antigens to elicit immune responses
Q39627674RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potency.
Q92063506Radiation-induced small extracellular vesicles as "carriages" promote tumor antigen release and trigger antitumor immunity
Q27487800Rapid Determination of HLA B*07 Ligands from the West Nile Virus NY99 Genome
Q33882818Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation
Q33222048Rapid and sensitive identification of major histocompatibility complex class I-associated tumor peptides by Nano-LC MALDI MS/MS.
Q52051973Rapid epitope identification from complex class-II-restricted T-cell antigens.
Q30217177Rapid generation of a mouse model for Middle East respiratory syndrome
Q37862710Rapid molecular dissection of viral and bacterial immunomes
Q30844919Rare, structurally homologous self-peptides promote thymocyte positive selection
Q48725100Rational design of diagnostic and vaccination strategies for tuberculosis.
Q34548080Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability.
Q28080312Recent advances in T-cell engineering for use in immunotherapy
Q42148984Recognition of class I MHC by a rat Ly49 NK cell receptor is dependent on the identity of the P2 anchor amino acid of bound peptide
Q24672952Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes
Q78429536Recovery of known T-cell epitopes by computational scanning of a viral genome
Q24307979Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing
Q42996980Relation of pretreatment sequence diversity in NS5A region of HCV genotype 1 with immune response between pegylated-INF/ribavirin therapy outcomes.
Q27485882Reliable prediction of T-cell epitopes using neural networks with novel sequence representations
Q98951948Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction
Q35784865Replication-Competent Foamy Virus Vaccine Vectors as Novel Epitope Scaffolds for Immunotherapy
Q40185976Rescue of the immunotherapeutic potential of a novel T cell epitope in the Epstein-Barr virus latent membrane protein 2.
Q35149956Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains
Q30840526Response to M. tuberculosis selected RD1 peptides in Ugandan HIV-infected patients with smear positive pulmonary tuberculosis: a pilot study
Q33444815Retracted: Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection
Q34495529Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion
Q36471831Reverse immunology approach for the identification of CD8 T-cell-defined antigens: advantages and hurdles
Q37844333Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development
Q42582499Rhesus macaque KIR bind human MHC class I with broad specificity and recognize HLA-C more effectively than HLA-A and HLA-B
Q37099986Robust quantitative modeling of peptide binding affinities for MHC molecules using physical-chemical descriptors
Q40659815Role of MHC II affinity and molecular mimicry in defining anti-HER-2/neu MAb-3 linear peptide epitope.
Q37107843Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies
Q41726495Role of peptide processing predictions in T cell epitope identification: contribution of different prediction programs.
Q34576423Roles of heat-shock proteins in innate and adaptive immunity
Q100395455SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition
Q51958531SNEP: SNP-derived epitope prediction program for minor H antigens.
Q34547980SVMHC: a server for prediction of MHC-binding peptides
Q33261251SVRMHC prediction server for MHC-binding peptides
Q24651238Sampling of major histocompatibility complex class I-associated peptidome suggests relatively looser global association of HLA-B*5101 with peptides
Q38704265Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen
Q47148622Scientific Opinion on the assessment of allergenicity of GM plants and microorganisms and derived food and feed
Q33770310Screening of human tumor antigens for CD4 T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries
Q34765261Scrutinizing MHC-I binding peptides and their limits of variation
Q30884495Selecting informative data for developing peptide-MHC binding predictors using a query by committee approach.
Q42248450Selection of conserved epitopes from hepatitis C virus for pan-populational stimulation of T-cell responses.
Q36825059Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities
Q36088409Seq2Logo: a method for construction and visualization of amino acid binding motifs and sequence profiles including sequence weighting, pseudo counts and two-sided representation of amino acid enrichment and depletion
Q38156565Sequence analysis of T-cell repertoires in health and disease.
Q35818040Sequence conservation analysis and in silico human leukocyte antigen-peptide binding predictions for the Mtb72F and M72 tuberculosis candidate vaccine antigens
Q42118490Sequence evolution of putative cytotoxic T cell epitopes in NS3 region of hepatitis C virus
Q28972497Sequence-based approach for rapid identification of cross-clade CD8+ T-cell vaccine candidates from all high-risk HPV strains
Q30532816Sequence-based in silico analysis of well studied hepatitis C virus epitopes and their variants in other genotypes (particularly genotype 5a) against South African human leukocyte antigen backgrounds
Q40104793Sharpening the Edge for Precision Cancer Immunotherapy: Targeting Tumor Antigens through Oncolytic Vaccines
Q42247561Short peptide sequence identity between human viruses and HLA-B27-binding human 'self' peptides
Q34695369Short-term in-vitro expansion improves monitoring and allows affordable generation of virus-specific T-cells against several viruses for a broad clinical application
Q51935955SiPep: a system for the prediction of tissue-specific minor histocompatibility antigens.
Q27312114Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz
Q30009990Simultaneous alignment and clustering of peptide data using a Gibbs sampling approach
Q51551323Social discrimination by quantitative assessment of immunogenetic similarity.
Q39123538Soluble HLA technology as a strategy to evaluate the impact of HLA mismatches
Q41325257Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency
Q34279102Soluble plasma HLA peptidome as a potential source for cancer biomarkers
Q47840879SopB of Salmonella enterica serovar Typhimurium is a potential DNA vaccine candidate in conjugation with live attenuated bacteria
Q54296983Specific CD8⁺ T cells recognize human herpesvirus 6B.
Q50654687Specific cytotoxic T-cell immune responses against autoantigens recognized by chronic lymphocytic leukaemia cells.
Q39575598Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
Q40794811Stability and CTL activity of N-terminal glutamic acid containing peptides
Q34312500State of the art and challenges in sequence based T-cell epitope prediction
Q45371304Stepwise identification of HLA-A*0201-restricted CD8+ T-cell epitope peptides from herpes simplex virus type 1 genome boosted by a StepRank scheme
Q82702663Steric recognition of T-cell receptor contact residues is required to map mutant epitopes by immunoinformatical programmes
Q34165879Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes
Q40649080Stimulation of tumor-reactive T lymphocytes using mixtures of synthetic peptides derived from tumor-associated antigens with diverse MHC binding affinities
Q42861769Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools
Q35077813Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection
Q30388011Structural and Biochemical Analyses of Swine Major Histocompatibility Complex Class I Complexes and Prediction of the Epitope Map of Important Influenza A Virus Strains.
Q34823910Structural basis of immunogenicity
Q27625365Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice
Q46941039Structural definition of the H-2Kd peptide-binding motif
Q33786803Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes
Q35875761Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease
Q90290722Structure Based Prediction of Neoantigen Immunogenicity
Q37012868Structure and function of major histocompatibility complex class I antigens
Q40284359Structure of the transporter associated with antigen processing trapped by herpes simplex virus
Q90735752Structure-based Methods for Binding Mode and Binding Affinity Prediction for Peptide-MHC Complexes
Q28251858Survivin-derived peptide epitopes and their role for induction of antitumor immunity in hematological malignancies
Q39843759Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice
Q47133530Synthetic peptides mimicking lipopolysaccharide as a potential vaccine candidates against Vibrio cholerae serogroup O1.
Q33510342Systematic characterisation of cellular localisation and expression profiles of proteins containing MHC ligands
Q58587953Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes
Q26782580Systems Biology Approach for Cancer Vaccine Development and Evaluation
Q38207141Systems vaccinology for cancer vaccine development
Q42648564T cell epitope "hotspots" on the HIV Type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry
Q35143307T cell epitope identification for bovine vaccines: an epitope mapping method for BoLA A-11.
Q33965405T cell epitope specificity and pathogenesis of mouse hepatitis virus-1-induced disease in susceptible and resistant hosts.
Q26787014T cell epitopes and post-translationally modified epitopes in type 1 diabetes
Q47582356T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer
Q34120055T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice
Q45364496T cell responses to bluetongue virus are directed against multiple and identical CD4+ and CD8+ T cell epitopes from the VP7 core protein in mouse and sheep.
Q21559508T cell responses to human endogenous retroviruses in HIV-1 infection
Q36210864T cell-mediated immunotherapy of metastases: state of the art in 2005.
Q39628181T cells reactive with HLA-A*0201 peptides from the histone demethylase JARID1B are found in the circulation of breast cancer patients
Q73006409T- and B-cell epitopes in the secreted Mycobacterium bovis antigen MPB70 in mice
Q37575359T-cell epitope mapping
Q35918501T-cell epitope peptide vaccines.
Q30486286T-cell epitope prediction: rescaling can mask biological variation between MHC molecules
Q36702419T-cell epitope vaccine design by immunoinformatics
Q34151667T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS.
Q38871209T-cell responses to oncogenic merkel cell polyomavirus proteins distinguish patients with merkel cell carcinoma from healthy donors
Q38372371TANTIGEN: a comprehensive database of tumor T cell antigens
Q35377746TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes.
Q28481206TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules
Q35063474Tapasin discriminates peptide-human leukocyte antigen-A*02:01 complexes formed with natural ligands
Q39595809Target structures of the CD8(+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited.
Q39026731Targeting high-grade B cell lymphoma with CD19-specific T cells
Q39149196Targeting neoantigens to augment antitumour immunity
Q38863894Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice.
Q37363754Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation
Q90232644Targeting self and neo-epitopes with a modular self-adjuvanting cancer vaccine
Q56897975Tat protein vaccination of cynomolgus macaques influences SHIV-89.6P cy243 epitope variability
Q36745749Telomerase immunity from bench to bedside: round one.
Q41827687TepiTool: A Pipeline for Computational Prediction of T Cell Epitope Candidates
Q40454951Testing the role of gp96 as peptide chaperone in antigen processing.
Q35948350Textmining in support of knowledge discovery for vaccine development
Q39145269The 'peptidome' of tumour-derived chaperone-rich cell lysate anti-cancer vaccines reveals potential tumour antigens that stimulate tumour immunity
Q61910266The CD68 protein as a potential target for leukaemia-reactive CTL
Q35745162The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study
Q35105393The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection
Q38301380The HLA-A*0201-restricted minor histocompatibility antigen HA-1H peptide can also be presented by another HLA-A2 subtype, A*0206.
Q30400430The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
Q42317060The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA.
Q36509857The MHC class I peptide repertoire is molded by the transcriptome.
Q38663365The Role of Multiscale Protein Dynamics in Antigen Presentation and T Lymphocyte Recognition
Q38753386The Role of Neoantigens in Naturally Occurring and Therapeutically Induced Immune Responses to Cancer
Q34146229The SSX family of cancer-testis antigens as target proteins for tumor therapy
Q34324298The Trypanosoma cruzi flagellum is discarded via asymmetric cell division following invasion and provides early targets for protective CD8⁺ T cells
Q30444065The contributions of mass spectrometry to understanding of immune recognition by T lymphocytes
Q42994117The core-specific precursor T cell response is directed to the N-terminal and central parts of the protein and positively correlates to the viral load in chronically HCV-infected patients
Q39814591The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.
Q39422790The development of Chinese specific human cytomegalovirus polyepitope recombinant vaccine
Q38818906The diagnostic potential of MPT63-derived HLA-A*0201-restricted CD8+ T-cell epitopes for active pulmonary tuberculosis
Q39084138The elucidation of non-classical MHC class II antigen processing through the study of viral antigens
Q38062377The epitopes in wheat proteins for defining toxic units relevant to human health
Q47569740The generation of a simian adenoviral vectored HCV vaccine encoding genetically conserved gene segments to target multiple HCV genotypes
Q51987808The heat shock protein Hsp70 enhances antigen-specific proliferation of human CD4+ memory T cells.
Q37848454The host selects mucosal and luminal associations of coevolved gut microorganisms: a novel concept
Q24296246The human cathepsin H gene encodes two novel minor histocompatibility antigen epitopes restricted by HLA-A*3101 and -A*3303
Q39182194The human leukocyte antigen-presented ligandome of B lymphocytes
Q34288498The identification of HLA class II-restricted T cell epitopes to vaccinia virus membrane proteins
Q39090059The immunogenicity of a novel cytotoxic T lymphocyte epitope from tumor antigen PL2L60 could be enhanced by 4-chlorophenylalanine substitution at position 1.
Q36927645The immunoinformatics of cancer immunotherapy
Q36457849The impact of HLA class I and EBV latency-II antigen-specific CD8(+) T cells on the pathogenesis of EBV(+) Hodgkin lymphoma
Q27664962The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Q50113126The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in Rheumatoid Arthritis.
Q36291919The role of computational models of the immune system in designing vaccination strategies
Q47190955The role of mass spectrometry and proteogenomics in the advancement of HLA epitope prediction
Q40895891The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules
Q56879701The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage
Q33221191The sentinel within: exploiting the immune system for cancer biomarkers
Q33264233The separate and combined effects of MHC genotype, parasite clone, and host gender on the course of malaria in mice
Q46396844The susceptible HLA class II alleles and their presenting epitope(s) in Goodpasture's disease.
Q38915023The viral transcription group determines the HLA class I cellular immune response against human respiratory syncytial virus
Q36031220The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response
Q35826752Therapeutic Vaccine Strategies against Human Papillomavirus
Q35193892Therapeutic cancer vaccines and translating vaccinomics science to the global health clinic: emerging applications toward proof of concept
Q36948849Therapeutic effect of a T helper cell supported CTL response induced by a survivin peptide vaccine against murine cerebral glioma
Q35604228Therapeutic vaccination for chronic diseases: a new class of drugs in sight
Q37208000Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal
Q35784696Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection
Q38161480Tools and methods for identification and analysis of rare antigen-specific T lymphocytes.
Q38650013Tools to define the melanoma-associated immunopeptidome.
Q36762526Toward a multiscale model of antigen presentation in immunity
Q37939072Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools.
Q38088325Towards in silico design of epitope-based vaccines
Q96641056Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire
Q35005960Towards patient-specific tumor antigen selection for vaccination
Q55640745Translating Immunopeptidomics to Immunotherapy-Decision-Making for Patient and Personalized Target Selection.
Q41828121Translation from the 5' untranslated region shapes the integrated stress response
Q36685319Transport of misfolded endoplasmic reticulum proteins to the cell surface by MHC class II molecules
Q52619024Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine.
Q28483146Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine
Q35160569Tumor antigens and proteomics from the point of view of the major histocompatibility complex peptides
Q28082704Tumor neoantigens: building a framework for personalized cancer immunotherapy
Q35671699Tumor vaccines.
Q89965816Tumor-Specific T Cell Activation in Malignant Brain Tumors
Q33459720Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity
Q34224580Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides
Q36134088Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis
Q38787035Unmasking targets of antitumor immunity via high-throughput antigen profiling
Q30391717Unsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide-HLA Interactions
Q39639898Unusual viral ligand with alternative interactions is presented by HLA-Cw4 in human respiratory syncytial virus-infected cells
Q40048119Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices
Q34973081Uroplakin peptide-specific autoimmunity initiates interstitial cystitis/painful bladder syndrome in mice
Q57537584Use of Bioinformatics to Predict MHC Ligands and T-Cell Epitopes
Q57537680Use of bioinformatics to predict MHC ligands and T-cell epitopes: Application to epitope-driven vaccine design
Q34815630Use of class II tetramers for identification of CD4+ T cells
Q34782568Use of transgenic HLA A*0201/Kb and HHD II mice to evaluate frequency of cytomegalovirus IE1-derived peptide usage in eliciting human CD8 cytokine response
Q30599291Using databases and data mining in vaccinology
Q35031973Using the World Wide Web for predicting CTL epitopes
Q36605186Vaccination against type 1 angiotensin receptor prevents streptozotocin-induced diabetic nephropathy
Q36565705Vaccination using peptides spanning the SYT-SSX tumor-specific translocation
Q45324559Vaccination with recombinant adenovirus expressing peste des petits ruminants virus-F or -H proteins elicits T cell responses to epitopes that arises during PPRV infection
Q34194709Vaccination with the recombinant Brucella outer membrane protein 31 or a derived 27-amino-acid synthetic peptide elicits a CD4+ T helper 1 response that protects against Brucella melitensis infection
Q35218994Vaccines targeting the cancer-testis antigen SSX-2 elicit HLA-A2 epitope-specific cytolytic T cells.
Q21089599Vaccines: from empirical development to rational design
Q37089515Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humans
Q42730634Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA
Q36553635Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans
Q21328677Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development
Q39791206Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.
Q35665799Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease.
Q57063675Viral bioinformatics
Q39860756Viral fitness implications of variation within an immunodominant CD8+ T-cell epitope of HIV-1.
Q42989673Virological and epitope evolution of HCV infection from acute hepatitis C to subsequent episodes of HCV-related acute liver cell necrosis
Q37206378Viruses selectively mutate their CD8+ T-cell epitopes--a large-scale immunomic analysis
Q34137664Whole genomes of Chandipura virus isolates and comparative analysis with other rhabdoviruses
Q33916280Whole-genome immunoinformatic analysis of F. tularensis: predicted CTL epitopes clustered in hotspots are prone to elicit a T-cell response
Q36047531ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes
Q35837827Zooming into the binding groove of HLA molecules: which positions and which substitutions change peptide binding most?
Q85076205[Prostate carcinoma: vaccination as a new option for treatment]
Q89850600dbPepNeo: a manually curated database for human tumor neoantigen peptides
Q30157638iSPOT: a web tool for the analysis and recognition of protein domain specificity
Q37202382sNebula, a network-based algorithm to predict binding between human leukocyte antigens and peptides
Q45875096ΔE1 and high-capacity adenoviral vectors expressing full-length codon-optimized merozoite surface protein 1 for vaccination against Plasmodium falciparum

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