scholarly article | Q13442814 |
P50 | author | Julio Montaner | Q1712378 |
Bruce D. Walker | Q23770361 | ||
Chanson J Brumme | Q30389061 | ||
Bette Korber | Q30505218 | ||
Nicole Frahm | Q85203972 | ||
David Heckerman | Q89548037 | ||
Richard Harrigan | Q92586267 | ||
James J Szinger | Q117221641 | ||
Celia Chui | Q117221668 | ||
Robert S Hogg | Q37837778 | ||
Christian Brander | Q42392436 | ||
Zabrina L Brumme | Q55135335 | ||
Tanmoy Bhattacharya | Q55414889 | ||
P2093 | author name string | Marcus Daniels | |
Theresa Mo | |||
Carl Kadie | |||
Jonathan Carlson | |||
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Impaired processing and presentation of cytotoxic-T-lymphocyte (CTL) epitopes are major escape mechanisms from CTL immune pressure in human immunodeficiency virus type 1 infection | Q35542741 | ||
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Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child | Q36684112 | ||
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HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity | Q43438499 | ||
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The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage | Q56879701 | ||
Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations | Q56880587 | ||
Evolution and transmission of stable CTL escape mutations in HIV infection | Q56880602 | ||
Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression | Q71803154 | ||
Definition of specific peptide motifs for four major HLA-A alleles | Q72332860 | ||
Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS | Q73034306 | ||
Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level | Q74171545 | ||
Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy | Q77230682 | ||
CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides | Q81415844 | ||
P275 | copyright license | Creative Commons CC0 License | Q6938433 |
P6216 | copyright status | copyrighted, dedicated to the public domain by copyright holder | Q88088423 |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e94 | |
P577 | publication date | 2007-07-01 | |
P1433 | published in | PLOS Pathogens | Q283209 |
P1476 | title | Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1 | |
P478 | volume | 3 |
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Q34302276 | Adaptive evolution of HIV at HLA epitopes is associated with ethnicity in Canada |
Q30386701 | Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs. |
Q33687232 | Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics |
Q42187290 | Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals |
Q27655357 | Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance |
Q40851822 | Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection |
Q36540029 | CD4+ target cell availability determines the dynamics of immune escape and reversion in vivo |
Q26781511 | Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs |
Q92701175 | Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure |
Q34456570 | Co-operative additive effects between HLA alleles in control of HIV-1 |
Q33680623 | CodonTest: modeling amino acid substitution preferences in coding sequences |
Q36414604 | Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1. |
Q33966673 | Counteraction of HLA-C-mediated immune control of HIV-1 by Nef. |
Q42211756 | Cytotoxic T-lymphocyte escape mutations identified by HLA association favor those which escape and revert rapidly |
Q28610686 | Declines in highly active antiretroviral therapy initiation at CD4 cell counts ≤ 200 cells/μL and the contribution of diagnosis of HIV at CD4 cell counts ≤ 200 cells/μL in British Columbia, Canada |
Q27675464 | Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity |
Q34308788 | Early immune adaptation in HIV-1 revealed by population-level approaches |
Q34295972 | Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection |
Q42115872 | Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages. |
Q46972940 | Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort |
Q35535663 | Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection |
Q34172358 | Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses |
Q37095345 | Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China |
Q58767928 | Extensive host immune adaptation in a concentrated North American HIV epidemic |
Q34295981 | Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression |
Q33394563 | Frequent toggling between alternative amino acids is driven by selection in HIV-1 |
Q36845893 | Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes |
Q57285044 | Genotypic and Mechanistic Characterization of Subtype-specific HIV Adaptation to Host Cellular Immunity |
Q34594538 | HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes |
Q36531107 | HIV-1 Nef in macrophage-mediated disease pathogenesis. |
Q36926697 | HIV-1 Nef: at the crossroads |
Q34808574 | HIV-1 clade B pol evolution following primary infection |
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Q36748059 | HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load |
Q35184356 | HLA-B57 and gender influence the occurrence of tuberculosis in HIV infected people of south India |
Q37051649 | HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection |
Q33494829 | HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins |
Q33612214 | HLA-associated immune pressure on Gag protein in CRF01_AE-infected individuals and its association with plasma viral load |
Q37127920 | HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers |
Q37051248 | HLA/KIR restraint of HIV: surviving the fittest |
Q35214354 | High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection |
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Q30424366 | Human immunodeficiency virus vaccine trials |
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Q36943363 | Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples |
Q28394085 | Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships |
Q34657787 | Immune activation promotes evolutionary conservation of T-cell epitopes in HIV-1. |
Q35798108 | Immune-mediated attenuation of HIV-1 |
Q36984267 | Impact of pre-adapted HIV transmission. |
Q101564241 | Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals |
Q33963989 | Impaired replication capacity of acute/early viruses in persons who become HIV controllers |
Q34070640 | Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection |
Q37200459 | Influence of HLA-C expression level on HIV control |
Q30710200 | Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways |
Q35567805 | Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications |
Q92523449 | Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study |
Q33879572 | Maintenance or emergence of chronic phase secondary cytotoxic T lymphocyte responses after loss of acute phase immunodominant responses does not protect SIV-infected rhesus macaques from disease progression |
Q36315090 | Mapping protease inhibitor resistance to human immunodeficiency virus type 1 sequence polymorphisms within patients. |
Q36898637 | Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection |
Q37808509 | Models of RNA virus evolution and their roles in vaccine design |
Q104486611 | Mucosal IL-4R antagonist HIV vaccination with SOSIP-gp140 booster can induce high-quality cytotoxic CD4+/CD8+ T cells and humoral responses in macaques |
Q34016464 | Nef-specific CD45RA+ CD8+ T cells secreting MIP-1beta but not IFN-gamma are associated with nonprogressive HIV-1 infection. |
Q35616586 | Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences |
Q54233740 | Novel HLA class I associations with HIV-1 control in a unique genetically admixed population. |
Q33517082 | Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1. |
Q33385995 | Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag. |
Q37785949 | Prime-boost immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1. |
Q34841789 | Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations |
Q34034422 | Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure |
Q37099792 | Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. |
Q33747537 | Quantifying the impact of human immunodeficiency virus-1 escape from cytotoxic T-lymphocytes |
Q35949014 | Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population |
Q34042642 | Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections |
Q46281150 | Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals |
Q54599332 | Reverse transcriptase mutation K65N confers a decreased replication capacity to HIV-1 in comparison to K65R due to a decreased RT processivity. |
Q42209395 | Role of individual's T-cell immunome in controlling HIV-1 progression |
Q27313564 | SIV genome-wide pyrosequencing provides a comprehensive and unbiased view of variation within and outside CD8 T lymphocyte epitopes |
Q41390297 | Selection pressure in CD8⁺ T-cell epitopes in the pol gene of HIV-1 infected individuals in Colombia. A bioinformatic approach |
Q36433533 | Short Communication: Nucleotide Variation and Positively Selected Sites in HIV Type 1 Reverse Transcriptase Among Heterosexual Transmission Pairs |
Q36791067 | Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiency. |
Q31151639 | Statistical resolution of ambiguous HLA typing data |
Q27680531 | Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection |
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Q30486286 | T-cell epitope prediction: rescaling can mask biological variation between MHC molecules |
Q37333743 | T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces |
Q33490243 | The distribution of CTL epitopes in HIV-1 appears to be random, and similar to that of other proteomes |
Q37927233 | The emerging role of HLA-C in HIV-1 infection |
Q33378477 | The evolutionary selective advantage of HIV-1 escape variants and the contribution of escape to the HLA-associated risk of AIDS progression |
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