| scholarly article | Q13442814 |
| P50 | author | Philip J. R. Goulder | Q72618990 |
| Andrew Prendergast | Q77768844 | ||
| Jianming Tang | Q45997233 | ||
| Philippa C Matthews | Q50981209 | ||
| Jonathan Carlson | Q57415421 | ||
| P2093 | author name string | Richard A Kaslow | |
| Karina Yusim | |||
| Susan Allen | |||
| Eric Hunter | |||
| Anju Bansal | |||
| Cynthia A Derdeyn | |||
| Joseph Mulenga | |||
| Paul A Goepfert | |||
| Paul Farmer | |||
| David Heckerman | |||
| Wendy Lumm | |||
| P2860 | cites work | Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS | Q73034306 |
| HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors | Q78342521 | ||
| CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides | Q81415844 | ||
| CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract | Q22242965 | ||
| Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1 | Q24673636 | ||
| Viral Sequence Evolution in Acute Hepatitis C Virus Infection | Q27484985 | ||
| HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. | Q33262230 | ||
| Leveraging hierarchical population structure in discrete association studies | Q33289961 | ||
| Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1 | Q33290217 | ||
| HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24. | Q33299493 | ||
| Molecular epidemiology of human immunodeficiency virus type 1 transmission in a heterosexual cohort of discordant couples in Zambia | Q34327190 | ||
| Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma | Q34332166 | ||
| Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover | Q34692601 | ||
| HIV and SIV CTL escape: implications for vaccine design | Q35852284 | ||
| Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression | Q35857259 | ||
| Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection | Q35947590 | ||
| Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes | Q36229197 | ||
| Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations | Q36238124 | ||
| Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication | Q36315510 | ||
| Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. | Q36315572 | ||
| Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection | Q36399423 | ||
| Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. | Q36403330 | ||
| Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo | Q36650992 | ||
| Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa. | Q37357668 | ||
| Differential expression of human major histocompatibility class I loci: HLA-A, -B, and -C. | Q40894117 | ||
| Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection | Q43542210 | ||
| Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. | Q44291572 | ||
| Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study | Q45743784 | ||
| HIV evolution: CTL escape mutation and reversion after transmission | Q47211742 | ||
| Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange. | Q47314618 | ||
| Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. | Q53588591 | ||
| Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations | Q56880587 | ||
| CD8+ T-cell responses to different HIV proteins have discordant associations with viral load | Q57259602 | ||
| Differential Immunogenicity of HIV‐1 Clade C Proteins in Eliciting CD8+and CD4+Cell Responses | Q57259616 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | evasion of host immune response | Q1660157 |
| viral load | Q2528140 | ||
| HIV transmission | Q49029021 | ||
| P304 | page(s) | 1009-1017 | |
| P577 | publication date | 2008-04-21 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients | |
| P478 | volume | 205 |
| Q36419536 | A gp41-based heteroduplex mobility assay provides rapid and accurate assessment of intrasubtype epidemiological linkage in HIV type 1 heterosexual transmission Pairs |
| Q34998830 | A randomised, placebo-controlled, first-in-human study of a novel clade C therapeutic peptide vaccine administered ex vivo to autologous white blood cells in HIV infected individuals |
| Q35190453 | A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses |
| Q38615326 | A strong case for viral genetic factors in HIV virulence |
| Q41919990 | A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies. |
| Q37423475 | A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda |
| Q34604811 | Adaptation of HIV-1 to human leukocyte antigen class I |
| Q33606936 | Adaptive changes in HIV-1 subtype C proteins during early infection are driven by changes in HLA-associated immune pressure. |
| Q34057338 | Antenatal HIV-1 RNA load and timing of mother to child transmission; a nested case-control study in a resource poor setting |
| Q42159772 | Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development |
| Q47108789 | Antigenic Variation and Immune Escape in the MTBC. |
| Q59356540 | Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection |
| Q37272098 | Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression. |
| Q37333757 | Balancing reversion of cytotoxic T-lymphocyte and neutralizing antibody escape mutations within human immunodeficiency virus type 1 Env upon transmission |
| Q35592229 | Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection |
| Q35894094 | Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort |
| Q33615194 | CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription |
| Q30432007 | CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis |
| Q36845904 | Central role of reverting mutations in HLA associations with human immunodeficiency virus set point |
| Q34142433 | Changes in function of HIV-specific T-cell responses with increasing time from infection |
| Q37452002 | Clade-specific evolution mediated by HLA-B*57/5801 in human immunodeficiency virus type 1 clade A1 p24. |
| Q92701175 | Clinical and evolutionary consequences of HIV adaptation to HLA: implications for vaccine and cure |
| Q34456570 | Co-operative additive effects between HLA alleles in control of HIV-1 |
| Q33429036 | Complexity of the inoculum determines the rate of reversion of SIV Gag CD8 T cell mutant virus and outcome of infection |
| Q95809269 | Crippling HIV one mutation at a time |
| Q36559632 | Cumulative impact of host and viral factors on HIV-1 viral-load control during early infection |
| Q91843704 | Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV |
| Q30410411 | Defining epitope coverage requirements for T cell-based HIV vaccines: theoretical considerations and practical applications |
| Q37346420 | Design and evaluation of multi-gene, multi-clade HIV-1 MVA vaccines |
| Q35664125 | Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection |
| Q37409268 | Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection |
| Q33907924 | Dynamics and timing of in vivo mutations at Gag residue 242 during primary HIV-1 subtype C infection |
| Q36276472 | Early HLA-B*57-restricted CD8+ T lymphocyte responses predict HIV-1 disease progression |
| Q34295972 | Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection |
| Q36015624 | Enhanced Recognition of HIV-1 Cryptic Epitopes Restricted by HLA Class I Alleles Associated With a Favorable Clinical Outcome |
| Q35665865 | Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope. |
| Q37273283 | Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients |
| Q35535663 | Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection |
| Q37615584 | Factors Associated with the Size of HIV DNA Reservoir |
| Q34743309 | Factors associated with viral rebound in HIV-1-infected individuals enrolled in a therapeutic HIV-1 gag vaccine trial |
| Q36086336 | Fitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection. |
| Q35219461 | Frequencies of Gag-restricted T-cell escape "footprints" differ across HIV-1 clades A1 and D chronically infected Ugandans irrespective of host HLA B alleles |
| Q36759719 | Frequent and variable cytotoxic-T-lymphocyte escape-associated fitness costs in the human immunodeficiency virus type 1 subtype B Gag proteins |
| Q37033282 | Functional consequences of human immunodeficiency virus escape from an HLA-B*13-restricted CD8+ T-cell epitope in p1 Gag protein. |
| Q38959897 | Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity |
| Q34178349 | Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters |
| Q41681556 | Genetic factors associated with slow progression of HIV among perinatally-infected Indian children |
| Q33921382 | HIV RNA level in early infection is predicted by viral load in the transmission source |
| Q37921949 | HIV controllers: a multifactorial phenotype of spontaneous viral suppression |
| Q35955635 | HIV molecular epidemiology: transmission and adaptation to human populations |
| Q34906292 | HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck |
| Q41811743 | HIV-1 Gag evolution in recently infected human leukocyte antigen-B*57 patients with low-level viremia. |
| Q33758570 | HIV-1 Transmission, Replication Fitness and Disease Progression |
| Q35229572 | HIV-1 replication capacity: Setting the pace of disease |
| Q35067451 | HIV-1 replication fitness of HLA-B*57/58:01 CTL escape variants is restored by the accumulation of compensatory mutations in gag |
| Q37856676 | HIV-1 replicative fitness in elite controllers |
| Q33642318 | HIV-1 vaccine development after STEP. |
| Q30355260 | HIV-1 variable loop 2 and its importance in HIV-1 infection and vaccine development |
| Q35753766 | HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. |
| Q40049698 | HLA based selection of epitopes offers a potential window of opportunity for vaccine design against HIV. |
| Q37081581 | HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703 |
| Q37643772 | HLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice |
| Q34341384 | HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function |
| Q37033250 | HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1. |
| Q33612214 | HLA-associated immune pressure on Gag protein in CRF01_AE-infected individuals and its association with plasma viral load |
| Q51767138 | HLA-mediated control of HIV and HIV adaptation to HLA. |
| Q34984762 | Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses |
| Q35188022 | High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection |
| Q37713976 | Host-specific adaptation of HIV-1 subtype B in the Japanese population |
| Q37033201 | Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point |
| Q35192955 | Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes |
| Q28394085 | Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationships |
| Q93000948 | Immune Control of HIV |
| Q37199493 | Immune activation and collateral damage in AIDS pathogenesis. |
| Q28086888 | Immune activation and paediatric HIV-1 disease outcome |
| Q34937296 | Immune escape from HIV-specific antibody-dependent cellular cytotoxicity (ADCC) pressure |
| Q35798108 | Immune-mediated attenuation of HIV-1 |
| Q34033051 | Immunity to HIV in Early Life |
| Q92376487 | Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia |
| Q35529735 | Immuno-epidemiological modeling of HIV-1 predicts high heritability of the set-point virus load, while selection for CTL escape dominates virulence evolution |
| Q59098671 | Immunology and the elusive AIDS vaccine |
| Q37356088 | Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection |
| Q34262204 | Impact of HLA selection pressure on HIV fitness at a population level in Mexico and Barbados |
| Q34753286 | Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence |
| Q34235198 | Impact of MHC class I diversity on immune control of immunodeficiency virus replication |
| Q34922094 | Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression |
| Q36394656 | Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome |
| Q36984267 | Impact of pre-adapted HIV transmission. |
| Q42208915 | Impaired Nef function is associated with early control of HIV-1 viremia |
| Q33963989 | Impaired replication capacity of acute/early viruses in persons who become HIV controllers |
| Q37547472 | Increased sequence coverage through combined targeting of variant and conserved epitopes correlates with control of HIV replication |
| Q35076519 | Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C. |
| Q28480902 | Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection |
| Q24629567 | Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers |
| Q36301732 | Lack of a significant impact of Gag-Protease-mediated HIV-1 replication capacity on clinical parameters in treatment-naive Japanese individuals |
| Q40449556 | Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants. |
| Q37738467 | Low level of HIV-1 evolution after transmission from mother to child |
| Q47296340 | Maintenance of AP-2 Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses |
| Q36898637 | Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection |
| Q37333818 | Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant |
| Q26866505 | Mechanisms of HIV protein degradation into epitopes: implications for vaccine design |
| Q37317714 | Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response |
| Q30992754 | Modelling the evolution and spread of HIV immune escape mutants |
| Q28086907 | Mutational escape of CD8+ T cell epitopes: implications for prevention and therapy of persistent hepatitis virus infections |
| Q56880081 | New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels |
| Q37243687 | Paediatric non-progression following grandmother-to-child HIV transmission |
| Q34686014 | Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation |
| Q36660299 | Prevalence of seroconversion symptoms and relationship to set-point viral load: findings from a subtype C epidemic, 1995-2009 |
| Q34841789 | Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations |
| Q33747537 | Quantifying the impact of human immunodeficiency virus-1 escape from cytotoxic T-lymphocytes |
| Q47552968 | Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient |
| Q37219577 | Rare HLA drive additional HIV evolution compared to more frequent alleles |
| Q42718488 | Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers |
| Q34243486 | Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation. |
| Q40349815 | Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression |
| Q35192975 | Replication-competent simian immunodeficiency virus (SIV) Gag escape mutations archived in latent reservoirs during antiretroviral treatment of SIV-infected macaques |
| Q33558599 | Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate |
| Q35229333 | Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression |
| Q33910862 | Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus |
| Q41923263 | Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape. |
| Q26772713 | Role of HLA Adaptation in HIV Evolution |
| Q34499377 | Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis |
| Q28607344 | Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa |
| Q43454270 | Specific antibody-dependent cellular cytotoxicity responses associated with slow progression of HIV infection |
| Q36639948 | Susan Allen: confronting HIV in Africa. Interview by Hema Bashyam |
| Q37789345 | T cell immunity in acute HIV-1 infection. |
| Q36363854 | Temporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression. |
| Q35105393 | The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection |
| Q42710662 | The STEP study provides a hint that vaccine induction of the right CD8+ T cell responses can facilitate immune control of HIV. |
| Q34642996 | The T-cell response to HIV. |
| Q33904028 | The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate |
| Q34015177 | The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing |
| Q34614862 | The immune response during acute HIV-1 infection: clues for vaccine development |
| Q43576040 | The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors |
| Q33515034 | Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection |
| Q33700493 | Timing of immune escape linked to success or failure of vaccination |
| Q37145270 | Transmission and long-term stability of compensated CD8 escape mutations |
| Q34780395 | Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor |
| Q34874985 | Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients |
| Q36086711 | Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity |
| Q36497283 | Vertical T cell immunodominance and epitope entropy determine HIV-1 escape |
| Q24600713 | Viral evolution and escape during acute HIV-1 infection |
| Q35077768 | Virological and immunological factors associated with HIV-1 differential disease progression in HLA-B 58:01-positive individuals |
| Q34040248 | Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective |
| Q39400038 | Virus-Host Gene Interactions Define HIV-1 Disease Progression. |
| Q30469621 | Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection |
| Q41814777 | Widespread impact of HLA restriction on immune control and escape pathways of HIV-1 |
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