Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

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Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1031512000
P356DOI10.1186/1742-4690-9-89
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/1742-4690-9-89
P8608Fatcat IDrelease_z6g2hsscdzfsvbcnpcjewua56m
P932PMC publication ID3496648
P698PubMed publication ID23110705
P5875ResearchGate publication ID232740526

P50authorBarton HaynesQ4865631
Andrew James McMichaelQ21165187
Alan S. PerelsonQ55719625
Guido FerrariQ56481169
M Anthony MoodyQ73297881
George M. ShawQ78514357
Josh A EudaileyQ88147253
Nilu GoonetillekeQ100456048
Bhavna HoraQ114512865
Fangping CaiQ114512866
Hongshuo SongQ114722126
Mark S DrinkerQ117248643
Joy PickeralQ125314693
Jeffrey W PavlicekQ125314735
Beatrice H. HahnQ55293537
Tanmoy BhattacharyaQ55414889
P2093author name stringHui Li
Feng Gao
Shilpa S Iyer
Michael K P Liu
Julie M Decker
Katharine J Bar
Anna Berg
P2860cites workVariable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) responseQ21131580
Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitorsQ28379411
Recombination rate and selection strength in HIV intra-patient evolutionQ28472689
HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapyQ29616404
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseQ29619994
Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time.Q30351457
Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleteriousQ31047702
Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantageQ33325923
A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progressionQ33604871
Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assayQ33814927
Dynamics and timing of in vivo mutations at Gag residue 242 during primary HIV-1 subtype C infectionQ33907924
Recombination in HIV-1Q57998149
High replication fitness and transmission efficiency of HIV-1 subtype C from India: Implications for subtype C predominanceQ83212088
Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assayQ34434646
Human immunodeficiency virus type 1 protease inhibitor drug-resistant mutants give discordant results when compared in single-cycle and multiple-cycle fitness assaysQ34489422
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1Q34545760
Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1.Q34717892
Analysis of low-frequency mutations associated with drug resistance to raltegravir before antiretroviral treatmentQ34737411
Estimate of effective recombination rate and average selection coefficient for HIV in chronic infectionQ34804767
Replicative fitness costs of nonnucleoside reverse transcriptase inhibitor drug resistance mutations on HIV subtype C.Q34933329
Fitness of drug resistant HIV-1: methodology and clinical implicationsQ35046895
Evolution of drug-resistant viral populations during interruption of antiretroviral therapyQ35077423
Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infectionQ35274776
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infectionQ35947590
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escapeQ36000736
Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.Q36315572
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.Q36376216
Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipientsQ36639954
Quantitation of human immunodeficiency virus type 1 infection kineticsQ36686530
CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemicQ37191866
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infectionQ37273158
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infectionQ37273195
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipientsQ37273283
Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infantQ37333818
Dynamics of HIV-1 recombination in its natural target cellsQ37356815
Primary infection by a human immunodeficiency virus with atypical coreceptor tropismQ38631923
Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progressionQ39534825
Estimating relative fitness in viral competition experiments.Q39597718
Fitness disadvantage of transitional intermediates contributes to dynamic change in the infecting-virus population during coreceptor switch in R5 simian/human immunodeficiency virus-infected macaquesQ41230660
High rate of genetic recombination in murine leukemia virus: implications for influencing proviral ploidyQ41496579
Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virusQ41611077
HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognitionQ41966337
Fitness of human immunodeficiency virus type 1 protease inhibitor-selected single mutantsQ45740545
HIV evolution: CTL escape mutation and reversion after transmissionQ47211742
Detection of minor drug-resistant populations by parallel allele-specific sequencing.Q54563995
P921main subjectHIVQ15787
evasion of host immune responseQ1660157
HIV transmissionQ49029021
P304page(s)89
P577publication date2012-10-30
P1433published inRetrovirologyQ15793508
P1476titleImpact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome
P478volume9

Reverse relations

cites work (P2860)
Q41919990A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.
Q34057942Analysis of HLA A*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial
Q37272098Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression.
Q34114798Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
Q34308788Early immune adaptation in HIV-1 revealed by population-level approaches
Q35247825Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR
Q37303016Factors affecting relative fitness measurements in pairwise competition assays of human immunodeficiency viruses
Q36086336Fitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection.
Q28487168HIV-1 Env C2-V4 diversification in a slow-progressor infant reveals a flat but rugged fitness landscape
Q36827382HIV-1 conserved-element vaccines: relationship between sequence conservation and replicative capacity
Q39080439Immune camouflage: relevance to vaccines and human immunology
Q61811049Interaction of the Host and Viral Genome and Their Influence on HIV Disease
Q50300594Kinetics of HIV-Specific CTL Responses Plays a Minimal Role in Determining HIV Escape Dynamics.
Q92486763Modelling and in vitro testing of the HIV-1 Nef fitness landscape
Q41213664Pairwise growth competition assay for determining the replication fitness of human immunodeficiency viruses
Q34686014Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation
Q35875253Recombination Enhances HIV-1 Envelope Diversity by Facilitating the Survival of Latent Genomic Fragments in the Plasma Virus Population.
Q37532983Relative resistance of HIV-1 founder viruses to control by interferon-alpha
Q42208022Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants.
Q37612507Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness
Q33910862Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus
Q36656789Short Communication: A Recombinant Variant with Increased Envelope Entry Efficiency Emerged During Early Infection of an HIV-1 Subtype C Dual Infected Rapid Progressor
Q38640293T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity
Q100456050The HIV-1 latent reservoir is largely sensitive to circulating T cells
Q41493589The host HLA-A*02 allele is associated with the response to pegylated interferon and ribavirin in patients with chronic hepatitis C virus infection
Q35377813The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations
Q37547702The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques.
Q37464540Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences
Q26861425Using nonhuman primates to model HIV transmission
Q26798040What do mathematical models tell us about killing rates during HIV-1 infection?

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