Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

scientific article published on June 2009

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.20090378
P932PMC publication ID2715054
P698PubMed publication ID19487424
P5875ResearchGate publication ID26258199

P50authorBarton HaynesQ4865631
Michael SaagQ6834090
Myron S. CohenQ16733099
Bette KorberQ30505218
Alan S. PerelsonQ55719625
Nicholas F ParrishQ56771203
Jesus F Salazar-GonzalezQ57415418
Brandon KeeleQ68690678
George M. ShawQ78514357
John C KappesQ92482518
Cynthia A DerdeynQ94562588
Katharine J BarQ102210398
Joshua BaalwaQ114512825
Katharina S ShawQ114512827
Elena E GiorgiQ122828494
Joseph MulengaQ122828500
Christina Ochsenbauer-JamborQ125314401
M Brad GuffeyQ125314582
Peter T. HraberQ37366689
Gerald H LearnQ54541884
Beatrice H. HahnQ55293537
Tanmoy BhattacharyaQ55414889
P2093author name stringHui Li
Martin Markowitz
Susan Allen
Matthias H Kraus
Eric Hunter
Shuyi Wang
Julie M Decker
Maria G Salazar
Katie L Davis
P2860cites workHIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBECQ21559422
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tractQ22242981
Transmission, acute HIV-1 infection and the quest for strategies to prevent infectionQ22251056
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
Marburgvirus genomics and association with a large hemorrhagic fever outbreak in AngolaQ24548936
Viral Sequence Evolution in Acute Hepatitis C Virus InfectionQ27484985
Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virusQ28302762
Antibody neutralization and escape by HIV-1Q29547345
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionQ29547852
Viral dynamics in human immunodeficiency virus type 1 infectionQ29547908
Rapid evolution of the neutralizing antibody response to HIV type 1 infectionQ29618603
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodiesQ29619015
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infectionQ29619099
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infectionQ29619124
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.Q29619254
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionQ29619510
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptaseQ29619994
Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1Q33402461
Clinical picture of primary HIV infection presenting as a glandular-fever-like illnessQ33447605
Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresisQ33881912
Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccinesQ33911935
Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infectionQ34228730
Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis.Q34717126
Diagnosis of primary HIV-1 infection and duration of follow-up after HIV exposure. Karolinska Institute Primary HIV Infection Study GroupQ64130059
Clinical and epidemiologic features of primary HIV infectionQ71182378
A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivoQ34858885
The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.Q35062297
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern AfricaQ35140032
Inhibiting sexual transmission of HIV-1 infectionQ35709090
Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.Q35830147
Rabies virus quasispecies: implications for pathogenesisQ35980649
Perils at mucosal front lines for HIV and SIV and their hostsQ36274922
Viral dynamics of acute HIV-1 infectionQ36375339
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte responseQ36399559
Antigenic conservation and immunogenicity of the HIV coreceptor binding siteQ36403587
Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved?Q36422860
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencingQ36540055
Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infectionQ36647820
Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasmaQ37051645
Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals.Q37110723
Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variantsQ37145228
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.Q37273086
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infectionQ37273195
High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccinationQ37471315
Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopesQ38979142
Identifying the target cell in primary simian immunodeficiency virus (SIV) infection: highly activated memory CD4(+) T cells are rapidly eliminated in early SIV infection in vivoQ39588498
Blood monocytes harbor HIV type 1 strains with diversified phenotypes including macrophage-specific CCR5 virusQ39609207
Contribution of Taq polymerase-induced errors to the estimation of RNA virus diversityQ40982856
Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infectionQ45738778
Modeling plasma virus concentration during primary HIV infectionQ45743854
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infectionQ45854355
Viral dynamics in primary HIV-1 infection. Karolinska Institutet Primary HIV Infection Study Group.Q52070829
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
phenotypeQ104053
HIV transmissionQ49029021
P304page(s)1273-1289
P577publication date2009-06-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleGenetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
P478volume206

Reverse relations

cites work (P2860)
Q55383445A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge.
Q46297514A Variance-Components Model for Distance-Matrix PhylogeneticReconstruction.
Q33825756A comparative proteomic analysis of the soluble immune factor environment of rectal and oral mucosa
Q35783015A critical question for HIV vaccine development: which antibodies to induce?
Q27024614A global approach to HIV-1 vaccine development
Q33966648A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251.
Q90066250A new cell line for assessing HIV-1 antibody dependent cellular cytotoxicity against a broad range of variants
Q36363866A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays
Q37410812A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains
Q33653774A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays
Q94947217A universal anti-HIV-1 Tat epitope vaccine that is fully synthetic and self-adjuvanting
Q36337888Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model.
Q30359547Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release
Q34185814Acute HIV-1 Infection
Q58038022Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level
Q36667979Adaptation to the interferon-induced antiviral state by human and simian immunodeficiency viruses
Q33961448Adoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques
Q47548907Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations.
Q35077677An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum
Q42038291An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.
Q30781299An evaluation of phylogenetic methods for reconstructing transmitted HIV variants using longitudinal clonal HIV sequence data
Q55516259An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development.
Q33627673Anti-HIV activity in cervical-vaginal secretions from HIV-positive and -negative women correlate with innate antimicrobial levels and IgG antibodies
Q55562325Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.
Q28081831Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis
Q35689392Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors
Q36164165Application of a case-control study design to investigate genotypic signatures of HIV-1 transmission
Q47146547Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?
Q92226023Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection
Q34728767BAsE-Seq: a method for obtaining long viral haplotypes from short sequence reads
Q37254470BLT humanized mice as model to study HIV vaginal transmission
Q35140968Barriers to mucosal transmission of immunodeficiency viruses
Q28082862Bottlenecks in HIV-1 transmission: insights from the study of founder viruses
Q39451862Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection
Q37397841Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission
Q36742476CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo.
Q92524713CD8 T cells targeting adapted epitopes in chronic HIV infection promote dendritic cell maturation and CD4 T cell trans-infection
Q30432007CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis
Q89686737CD8+ T cells in HIV control, cure and prevention
Q34291056Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells
Q38154038Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies
Q34539781Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children
Q36376213Central nervous system viral invasion and inflammation during acute HIV infection
Q34720281Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient
Q40393973Characterization of founder viruses in very early SIV rectal transmission
Q35140429Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry
Q34053295Characterization of neutralizing profiles in HIV-1 infected patients from whom the HJ16, HGN194 and HK20 mAbs were obtained
Q38721805Characterizing HIV-1 Splicing by Using Next-Generation Sequencing
Q37841429Chemokine-mediated immune responses in the female genital tract mucosa
Q90134557Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies
Q27691426Clinical significance of HIV-1 coreceptor usage
Q37152155Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis
Q54251489Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium.
Q36978861Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design
Q35219829Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection
Q41610618Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains
Q57796335Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth
Q35488153Conserved molecular signatures in gp120 are associated with the genetic bottleneck during simian immunodeficiency virus (SIV), SIV-human immunodeficiency virus (SHIV), and HIV type 1 (HIV-1) transmission
Q36288959Conserved signatures indicate HIV-1 transmission is under strong selection and thus is not a "stochastic" process
Q33857491Constrained use of CCR5 on CD4+ lymphocytes by R5X4 HIV-1: efficiency of Env-CCR5 interactions and low CCR5 expression determine a range of restricted CCR5-mediated entry
Q35826200Contribution of intra- and interhost dynamics to norovirus evolution
Q59358243Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses
Q35330357Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms
Q57468964Current and Future Therapeutic Strategies for Lentiviral Eradication from Macrophage Reservoirs
Q90859869Cyclophilin A protects HIV-1 from restriction by human TRIM5α
Q34413887De novo assembly of highly diverse viral populations
Q35140263Demographic processes affect HIV-1 evolution in primary infection before the onset of selective processes
Q37252894Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection
Q36885187Derivation of non-infectious envelope proteins from virions isolated from plasma negative for HIV antibodies
Q33951977Detection of inferred CCR5- and CXCR4-using HIV-1 variants and evolutionary intermediates using ultra-deep pyrosequencing
Q36736392Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIVSF162P3N-Infected Macaques
Q33922689Development of a contemporary globally diverse HIV viral panel by the EQAPOL program
Q34535266Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses
Q28551914Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus
Q36343848Differential evolution of a CXCR4-using HIV-1 strain in CCR5wt/wt and CCR5∆32/∆32 hosts revealed by longitudinal deep sequencing and phylogenetic reconstruction.
Q33827798Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production
Q30360141Differential sensitivities of tetherin isoforms to counteraction by primate lentiviruses.
Q36277153Differentiating founder and chronic HIV envelope sequences.
Q42276242Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells.
Q60952499Disparate impact on CD4 T cell count by two distinct HIV-1 phylogenetic clusters from the same clade
Q34503200Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies
Q36414547Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages
Q34315382Diversity of envelope genes from an uncloned stock of SIVmac251.
Q40040133Donor-Recipient Identification in Para- and Poly-phyletic Trees Under Alternative HIV-1 Transmission Hypotheses Using Approximate Bayesian Computation.
Q35168379Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR.
Q42251857Dynamics of in vitro fitness recovery of HIV-1.
Q36000736Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape
Q46046314Early sites of virus replication after oral SIVmac251 infection of infant macaques: implications for pathogenesis
Q37252793Effects of cellular activation on anti-HIV-1 restriction factor expression profile in primary cells
Q92772993Effects of the levonorgestrel-containing intrauterine device, copper intrauterine device, and levonorgestrel-containing oral contraceptive on susceptibility of immune cells from cervix, endometrium and blood to HIV-1 fusion measured ex vivo
Q35799147Efficiency of CCR5 coreceptor utilization by the HIV quasispecies increases over time, but is not associated with disease progression
Q39314021Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism
Q63246643Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA
Q36754296Efficient mucosal transmissibility but limited pathogenicity of R5 SHIV SF162P3N in Chinese-origin rhesus macaques
Q27329126Elimination of HIV-1-infected cells by broadly neutralizing antibodies
Q28482493Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing
Q38979760Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12.
Q37312719Enhancement of viral escape in HIV-1 Nef by STEP vaccination
Q40448856Enhancing Virion Tethering by BST2 Sensitizes Productively and Latently HIV-infected T cells to ADCC Mediated by Broadly Neutralizing Antibodies.
Q91802349Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection
Q37021717Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
Q34804767Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection
Q33727328Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
Q36095984Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality
Q34193198Evaluation of cervical mucosa in transmission bottleneck during acute HIV-1 infection using a cervical tissue-based organ culture
Q34819651Evidence for a continuous drift of the HIV-1 species towards higher resistance to neutralizing antibodies over the course of the epidemic
Q33676640Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model
Q58794804Evolutionary view of the AIDS process
Q33916640Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants.
Q36111516Factors Important to the Prioritization and Development of Successful Topical Microbicides for HIV-1
Q33602718Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild
Q42239239Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor.
Q36945699Future of phylogeny in HIV prevention
Q35629509GSK1265744 demonstrates robust in vitro activity against various clades of HIV-1.
Q59358201Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques
Q35748138Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides
Q35115599Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks
Q35826158Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages
Q45325228Genetic bottlenecks in intraspecies virus transmission
Q34290999Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeys
Q33838382Genital tract sequestration of SIV following acute infection
Q36909871Genome Sequences of a Novel HIV-1 Circulating Recombinant Form (CRF59_01B) Identified among Men Who Have Sex with Men in Northeastern China
Q36601113Genome Sequences of a Novel HIV-1 Circulating Recombinant Form, CRF55_01B, Identified in China
Q35289861Genotypic and functional properties of early infant HIV-1 envelopes
Q37460075Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C.
Q35110503Giant cell encephalitis and microglial infection with mucosally transmitted simian-human immunodeficiency virus SHIVSF162P3N in rhesus macaques
Q28265115Glycans, galectins, and HIV-1 infection
Q47555792Glycosyl-phosphatidylinositol-Anchored Anti-HIV Env Single Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity
Q40174150Glycosylation and oligomeric state of envelope protein might influence HIV-1 virion capture by α4β7 integrin.
Q36155024Glycosylation of simian immunodeficiency virus influences immune-tissue targeting during primary infection, leading to immunodeficiency or viral control
Q33967039Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.
Q37771138HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals
Q39520219HIV pre-exposure prophylaxis for women and infants prevents vaginal and oral HIV transmission in a preclinical model of HIV infection
Q28475647HIV promoter integration site primarily modulates transcriptional burst size rather than frequency
Q42212831HIV reverse-transcriptase drug resistance mutations during early infection reveal greater transmission diversity than in envelope sequences
Q37853935HIV sexual transmission and microbicides
Q36526615HIV transmission
Q36269097HIV transmission biology: translation for HIV prevention
Q34906292HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck
Q34342558HIV vaccines: lessons learned and the way forward
Q45378201HIV vaccines: mosaic approach to virus diversity
Q37851950HIV vaccines: progress to date.
Q36022372HIV-1 Genetic Variation Resulting in the Development of New Quasispecies Continues to Be Encountered in the Peripheral Blood of Well-Suppressed Patients
Q35995791HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity
Q35260218HIV-1 Subtype C Phylodynamics in the Global Epidemic
Q37287774HIV-1 Trans Infection of CD4(+) T Cells by Professional Antigen Presenting Cells
Q35067233HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo
Q38718438HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK Cells
Q36997294HIV-1 Vpu Mediates HLA-C Downregulation
Q35895988HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins
Q45323939HIV-1 and Hepatitis C virus selection bottleneck in Chinese people who inject drugs
Q55967625HIV-1 and the macrophage
Q27497560HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV
Q26825087HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies
Q34510531HIV-1 expressing the envelopes of transmitted/founder or control/reference viruses have similar infection patterns of CD4 T-cells in human cervical tissue ex vivo
Q91887203HIV-1 is more dependent on the K182 capsid residue than HIV-2 for interactions with CPSF6
Q35216488HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages
Q36526530HIV-1 pathogenesis: the virus
Q34050421HIV-1 replication in the central nervous system occurs in two distinct cell types.
Q35215387HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.
Q35196509HIV-1 target cells in the CNS.
Q35897398HIV-1 vaginal transmission: cell-free or cell-associated virus?
Q36767899HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
Q33753950HIV-Enhancing and HIV-Inhibiting Properties of Cationic Peptides and Proteins
Q37962420HIV/AIDS: 30 years of progress and future challenges.
Q35753766HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses.
Q33877425Hepatitis C virus transmission bottlenecks analyzed by deep sequencing.
Q60947056Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4 T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4
Q36827377Heterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock
Q35778333Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-α Resistance
Q33582135High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.
Q35188022High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection
Q28533522High prevalence of HIV-1 intersubtype B'/C recombinants among injecting drug users in Dehong, China
Q34115280High viral fitness during acute HIV-1 infection
Q30570557High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.
Q47551736Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.
Q59357225Host and Viral Factors Influencing Interplay between the Macrophage and HIV-1
Q21131400Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice
Q34486236Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission
Q30404393Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: a review
Q34407843Human immunodeficiency virus type-1 (HIV-1) continues to evolve in presence of broadly neutralizing antibodies more than ten years after infection
Q30424366Human immunodeficiency virus vaccine trials
Q36702615Human immunodeficiency viruses appear compartmentalized to the female genital tract in cross-sectional analyses but genital lineages do not persist over time
Q35192955Human leukocyte antigen variants B*44 and B*57 are consistently favorable during two distinct phases of primary HIV-1 infection in sub-Saharan Africans with several viral subtypes
Q33624872Humoral immune responses to HIV in the mucosal secretions and sera of HIV-infected women
Q97523157Hypoxic microenvironment shapes HIV-1 replication and latency
Q36023199Identical consensus sequence and conserved genomic polymorphism of hepatitis E virus during controlled interspecies transmission
Q39615794Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques.
Q36484034Identification of interdependent variables that influence coreceptor switch in R5 SHIV(SF162P3N)-infected macaques
Q35172385Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4
Q34038460Identifying and characterizing recently transmitted viruses
Q37644009Identifying recombination hot spots in the HIV-1 genome
Q57007956Immune Dysfunction and Coinfection with Human Immunodeficiency Virus and in Yi People
Q35855904Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection.
Q37789347Immune responses to HIV vaccines and potential impact on control of acute HIV-1 infection
Q35798108Immune-mediated attenuation of HIV-1
Q59098671Immunology and the elusive AIDS vaccine
Q36394656Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome
Q28481938Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
Q36495198Impact of mutation type and amplicon characteristics on genetic diversity measures generated using a high-resolution melting diversity assay
Q36984267Impact of pre-adapted HIV transmission.
Q28477088Implications of CTL-mediated killing of HIV-infected cells during the non-productive stage of infection
Q36978467Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy
Q98906744Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide
Q38009870Improved outlook on HIV-1 prevention and vaccine development
Q35996364Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.
Q47601205Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime-boost immunization
Q35694015Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.
Q34985572Inferring HIV Escape Rates from Multi-Locus Genotype Data
Q35861276Inhibitory Effect of Individual or Combinations of Broadly Neutralizing Antibodies and Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission
Q36086631Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication
Q36637034Innate and adaptive anti-HIV immune responses in the female reproductive tract
Q38170229Innate antiviral immune signaling, viral evasion and modulation by HIV-1.
Q38139934Innate immune evasion strategies by human immunodeficiency virus type 1.
Q33997880Innate immune recognition and activation during HIV infection
Q59357124Interaction Between Macrophage Migration Inhibitory Factor and CD74 in Human Immunodeficiency Virus Type I Infected Primary Monocyte-Derived Macrophages Triggers the Production of Proinflammatory Mediators and Enhances Infection of Unactivated CD4 T
Q33895123Interactions between HIV-1 and the cell-autonomous innate immune system.
Q89527088Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition
Q60045088Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines
Q35909939Investigating the Consequences of Interference between Multiple CD8+ T Cell Escape Mutations in Early HIV Infection
Q34280115Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum
Q37971871Key Concepts in the Early Immunology of HIV-1 Infection
Q38998925Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies
Q30414086Limited nucleotide changes in the Rev response element (RRE) during HIV-1 infection alter overall Rev-RRE activity and Rev multimerization
Q37362368Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection
Q34514374Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV
Q40118193Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens.
Q34792976Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.
Q36246646Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
Q92523449Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study
Q34802271Low Multiplicity of HIV-1 Infection and No Vaccine Enhancement in VAX003 Injection Drug Users
Q34120840Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys
Q37273086Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.
Q37618276M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures
Q35746218MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model
Q34681455MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1.
Q34742795Macrophage infection via selective capture of HIV-1-infected CD4+ T cells
Q34931267Macrophages and Cell-Cell Spread of HIV-1.
Q36737917Macrophages sustain HIV replication in vivo independently of T cells
Q35589028Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints.
Q42638889Maternal but Not Infant Anti-HIV-1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity
Q33545560Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences
Q28257799Mechanisms and modifications of naturally occurring host defense peptides for anti-HIV microbicide development
Q33753929Microbial Natural Product Alternariol 5-O-Methyl Ether Inhibits HIV-1 Integration by Blocking Nuclear Import of the Pre-Integration Complex.
Q36215001Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication
Q26999403Microbicides: topical prevention against HIV
Q34047780Minority variants of drug-resistant HIV.
Q30992754Modelling the evolution and spread of HIV immune escape mutants
Q35102285Models for predicting effective HIV chemoprevention in women
Q42744934Modulation of HIV-1 macrophage-tropism among R5 envelopes occurs before detection of neutralizing antibodies
Q92340123Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of In Vitro versus In Vivo Models
Q40238313Molecular Features of the V1-V4 Coding Region of Sexually Transmitted Human Immunodeficiency Virus Type 1.
Q28601925Molecular clock of HIV-1 envelope genes under early immune selection
Q89575126Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand
Q38749319Molecular evolution analysis of the human immunodeficiency virus type 1 envelope in simian/human immunodeficiency virus-infected macaques: implications for challenge dose selection.
Q36532973Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones
Q37442115Molecular linkage tracing of HIV-1 transmission events in seroconcordant couples in Guangxi Province, Southeastern China
Q33900353Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events
Q37555926Mucosal co-infections and HIV-1 transmission and pathogenesis
Q34275424Mucosal immunity in the female genital tract, HIV/AIDS
Q36957775Mucosal immunology of HIV infection
Q36559660Mucosal tissue tropism and dissemination of HIV-1 subtype B acute envelope-expressing chimeric virus
Q36492916Multiple NF-κB sites in HIV-1 subtype C long terminal repeat confer superior magnitude of transcription and thereby the enhanced viral predominance
Q36676496Multiplexed highly-accurate DNA sequencing of closely-related HIV-1 variants using continuous long reads from single molecule, real-time sequencing
Q96585128MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface
Q47141408Myeloid Cell Interaction with HIV: A Complex Relationship.
Q92325733N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation
Q27318354Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission
Q100946003Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses
Q36144358Near full-length HIV type 1M genomic sequences from Cameroon : Evidence of early diverging under-sampled lineages in the country
Q92239576Negative and Positive Selection Pressure During Sexual Transmission of Transmitted Founder HIV-1
Q34304203Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.
Q52660832Neutralization Sensitivity of a Novel HIV-1 CRF01_AE Panel of Infectious Molecular Clones.
Q37252676Neutralizing IgG at the portal of infection mediates protection against vaginal simian/human immunodeficiency virus challenge
Q34274849New approaches to design HIV-1 T-cell vaccines
Q33767191New directions for HIV vaccine development from animal models
Q56880081New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels
Q54250864Next-generation sequencing analysis of a cluster of hepatitis C virus infections in a haematology and oncology center.
Q64106336Next-generation sequencing of HIV-1 single genome amplicons
Q47547864On the Demographic and Selective Forces Shaping Patterns of Human Cytomegalovirus Variation within Hosts
Q41144784Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and Function
Q59360836PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C
Q30376824Pandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin.
Q92327047Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1
Q34614272Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased cloning
Q37528015Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose
Q36154787Pathogenic consequences of vaginal infection with CCR5-tropic simian-human immunodeficiency virus SHIVSF162P3N.
Q39305961Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections
Q42680526Patterns and rates of viral evolution in HIV-1 subtype B infected females and males
Q36166932Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: A Double-Blind Randomized Trial
Q40464768Phase 2 Study of the Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Men Who Have Sex With Men (HPTN 069/ACTG A5305).
Q58572549Phenotype, Polyfunctionality, and Antiviral Activity of Stimulated CD8 T-Cells From HIV Subjects Who Initiated cART at Different Time-Points After Acute Infection
Q36281817Phenotypic Correlates of HIV-1 Macrophage Tropism
Q35192915Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins
Q34336058Phenotypic properties of transmitted founder HIV-1
Q30404569Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants
Q58762598Phylogenetic approach to recover integration dates of latent HIV sequences within-host
Q37206422Phylogenetic inferences on HIV-1 transmission: implications for the design of prevention and treatment interventions
Q59355665Phylogenetic patterns recover known HIV epidemiological relationships and reveal common transmission of multiple variants
Q36684805Phylogenetically resolving epidemiologic linkage.
Q34062554Picomolar dichotomous activity of gnidimacrin against HIV-1.
Q30514155Pilot studies for development of an HIV subtype panel for surveillance of global diversity
Q37062259Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral Attachment
Q45373420Pooled peripheral blood mononuclear cells provide an optimized cellular substrate for human immunodeficiency virus Type 1 isolation during acute infection.
Q36479690Population genomics of intrapatient HIV-1 evolution
Q37272324Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells
Q34548621Preventing mucosal HIV transmission with topical microbicides: challenges and opportunities
Q36305433Previously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions
Q38631923Primary infection by a human immunodeficiency virus with atypical coreceptor tropism
Q34535698Prospective cohort study of HIV incidence and molecular characteristics of HIV among men who have sex with men(MSM) in Yunnan Province, China
Q36318184Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir
Q37547061Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities
Q37123237Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners
Q33869259R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes
Q37039116Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression
Q38849453Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection
Q30235024Recent Insights into the HIV/AIDS Pandemic
Q36286175Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission
Q35274968Recombination-mediated changes in coreceptor usage confer an augmented pathogenic phenotype in a nonhuman primate model of HIV-1-induced AIDS.
Q34269570Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.
Q34858876Recommendations for the follow-up of study participants with breakthrough HIV infections during HIV/AIDS biomedical prevention studies
Q28488527Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice
Q34042642Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections
Q33828583Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection
Q34243486Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation.
Q37532983Relative resistance of HIV-1 founder viruses to control by interferon-alpha
Q42208022Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants.
Q26767362Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence
Q34357068Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC.
Q37359047Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction.
Q33961704Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use.
Q37612507Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness
Q33910862Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus
Q84366798Roadblocks in HIV research: five questions
Q38213061Role of Fc-mediated antibody function in protective immunity against HIV-1.
Q36290832Role of Semen on Vaginal HIV-1 Transmission and Maraviroc Protection
Q27321665SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells
Q36146917SCOTTI: Efficient Reconstruction of Transmission within Outbreaks with the Structured Coalescent
Q35754196SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses
Q35581949SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasma
Q40084752Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women: A Phase 2 Randomized Trial
Q36184440Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations
Q35763313Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study
Q55261162Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions.
Q34721189Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins
Q30354832Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses
Q34295695Selective impact of HIV disease progression on the innate immune system in the human female reproductive tract
Q35018140Selective transmission of R5 HIV-1 variants: where is the gatekeeper?
Q92914545Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10
Q27331721Semen CD4+ T cells and macrophages are productively infected at all stages of SIV infection in macaques
Q33390855Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants
Q37336742Sequence and functional analysis of the envelope glycoproteins of hepatitis C virus variants selectively transmitted to a new host
Q34291084Sequence evolution of HIV-1 following mother-to-child transmission
Q30407004Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
Q37619686Serial cervicovaginal exposures with replication-deficient SIVsm induce higher dendritic cell (pDC) and CD4+ T-cell infiltrates not associated with prevention but a more severe SIVmac251 infection of rhesus macaques
Q92124025Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction
Q36756170Short Communication: Limited Anti-HIV-1 Activity of Maraviroc in Mucosal Tissues
Q42213317Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing
Q28478624Significantly longer envelope V2 loops are characteristic of heterosexually transmitted subtype B HIV-1 in Trinidad
Q35232811Simple mathematical models do not accurately predict early SIV dynamics
Q41867747Single genome amplification and direct amplicon sequencing of Plasmodium spp. DNA from ape fecal specimens
Q33625191Single genome amplification of proviral HIV-1 DNA from dried blood spot specimens collected during early infant screening programs in Lusaka, Zambia
Q36433960Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
Q35672336South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication
Q35925331Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection
Q37932048Specific microbicides in the prevention of HIV infection
Q40290521Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Q36053810Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses
Q33921277Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophages
Q28749596Structure activity relationship of dendrimer microbicides with dual action antiviral activity
Q35099081Structured observations reveal slow HIV-1 CTL escape
Q37704735Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection
Q30238730Survivors Remorse: antibody-mediated protection against HIV-1.
Q59352769Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs
Q34762224Synergy in monoclonal antibody neutralization of HIV-1 pseudoviruses and infectious molecular clones
Q88972036T cells establish and maintain CNS viral infection in HIV-infected humanized mice
Q33797892Taking multiple infections of cells and recombination into account leads to small within-host effective-population-size estimates of HIV-1
Q35985519Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability
Q34451254Targeted deep sequencing of HIV-1 using the IonTorrentPGM platform
Q30386549Targeting early infection to prevent HIV-1 mucosal transmission.
Q30382590Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.
Q37707466The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block.
Q40091554The HIV Genomic Incidence Assay Meets False Recency Rate and Mean Duration of Recency Infection Performance Standards
Q42314454The HIV-1 transmission bottleneck
Q92881205The Impact of Cellular Proliferation on the HIV-1 Reservoir
Q64885907The Pre-clinical Toolbox of Pharmacokinetics and Pharmacodynamics: in vitro and ex vivo Models.
Q59349051The Puzzle of HIV Neutral and Selective Evolution
Q27000032The Role of Cationic Polypeptides in Modulating HIV-1 Infection of the Cervicovaginal Mucosa
Q34642996The T-cell response to HIV.
Q40697873The V1 region of gp120 is preferentially selected during SIV/HIV transmission and is indispensable for envelope function and virus infection
Q34427503The chemokine receptor CCR5, a therapeutic target for HIV/AIDS antagonists, is critical for recovery in a mouse model of Japanese encephalitis
Q34217360The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid
Q30408103The development of an AIDS mucosal vaccine.
Q42593675The dynamics of HIV-1 adaptation in early infection.
Q37273195The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
Q28541827The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates
Q41555215The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB.
Q34614862The immune response during acute HIV-1 infection: clues for vaccine development
Q37481983The intra-host evolutionary and population dynamics of human immunodeficiency virus type 1: a phylogenetic perspective
Q40144203The mutable vaccine for mutable viruses
Q37683788The number and genetic relatedness of transmitted/founder virus impact clinical outcome in vaginal R5 SHIVSF162P3N infection
Q38021263The origin of genetic diversity in HIV-1.
Q35009308The presence of CXCR4-using HIV-1 prior to start of antiretroviral therapy is an independent predictor of delayed viral suppression
Q43576040The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors
Q37547702The selection of low envelope glycoprotein reactivity to soluble CD4 and cold during simian-human immunodeficiency virus infection of rhesus macaques.
Q36291699The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria
Q36846254Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire
Q34064859Timing and order of transmission events is not directly reflected in a pathogen phylogeny
Q33515034Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection
Q37089202Tissue-specific HIV-1 infection: why it matters
Q37233074Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs
Q54210802Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection.
Q42549345Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
Q35973063Transfer of Viral Communities between Human Individuals during Fecal Microbiota Transplantation
Q37464540Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences
Q33680395Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing
Q34874985Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients
Q40634933Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection
Q36607127Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
Q36000722Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7
Q34433975Transmitted/founder simian immunodeficiency virus envelope sequences in vesicular stomatitis and Semliki forest virus vector immunized rhesus macaques
Q57295387Ultra-long-acting removable drug delivery system for HIV treatment and prevention
Q90196947Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery
Q36068841Understanding Factors That Modulate the Establishment of HIV Latency in Resting CD4+ T-Cells In Vitro
Q30421453Universal amplification, next-generation sequencing, and assembly of HIV-1 genomes
Q92859937Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses
Q37395749Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes
Q26861425Using nonhuman primates to model HIV transmission
Q33778508Uterine epithelial cell regulation of DC-SIGN expression inhibits transmitted/founder HIV-1 trans infection by immature dendritic cells
Q37095477Vaginal concentrations of lactic acid potently inactivate HIV
Q58591002Variable infectivity and conserved engagement in cell-to-cell viral transfer by HIV-1 Env from Clade B transmitted founder clones
Q34170655Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis
Q34203163Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection
Q38739273Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication
Q36497283Vertical T cell immunodominance and epitope entropy determine HIV-1 escape
Q35593158Viral determinants of HIV-1 macrophage tropism
Q34270602Viral diversity and diversification of major non-structural genes vif, vpr, vpu, tat exon 1 and rev exon 1 during primary HIV-1 subtype C infection
Q33844706Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial
Q27013917Viral quasispecies evolution
Q39400038Virus-Host Gene Interactions Define HIV-1 Disease Progression.
Q35690771Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells
Q38936957Vpx complementation of 'non-macrophage tropic' R5 viruses reveals robust entry of infectious HIV-1 cores into macrophages.
Q33877419Wide variation in the multiplicity of HIV-1 infection among injection drug users
Q33619649Within-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV Infection

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