Using nonhuman primates to model HIV transmission

scientific article

Using nonhuman primates to model HIV transmission is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/COH.0B013E328361CFFF
P932PMC publication ID3999893
P698PubMed publication ID23666391

P50authorBrandon KeeleQ68690678
P2093author name stringChristine M. Fennessey
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Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and disseminationQ33582077
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Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposureQ36667917
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Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.Q37273086
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Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeysQ34120840
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The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeysQ35382944
TRIM5α does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposureQ35531415
SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasmaQ35581949
Durable protection from vaginal simian-human immunodeficiency virus infection in macaques by tenofovir gel and its relationship to drug levels in tissueQ35665851
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeysQ35729899
The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling studyQ35742086
SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responsesQ35754196
HIV prevention by oral preexposure prophylaxisQ35765743
Expression of structural proteins in human female and male genital epithelia and implications for sexually transmitted infectionsQ35790984
Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophagesQ35826158
Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaQ35826525
Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac2Q35867976
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escapeQ36000736
A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challengeQ36024470
Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeysQ36155555
Limited SHIV env diversification in macaques failing oral antiretroviral pre-exposure prophylaxisQ36299730
Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genomeQ36394656
Functional perturbation of classical natural killer and innate lymphoid cells in the oral mucosa during SIV infectionQ36516875
HIV transmissionQ36526615
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencingQ36540055
Impact of mucosal inflammation on oral simian immunodeficiency virus transmissionQ36559896
Effect of early anti-retroviral therapy on the pathogenic changes in mucosal tissues of SIV infected rhesus macaques.Q36604359
Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaquesQ36628606
DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challengeQ36637349
Antibodies to gp120 and PD-1 expression on virus-specific CD8+ T cells in protection from simian AIDSQ36667821
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectHIV transmissionQ49029021
P304page(s)280-7
P577publication date2013-07-01
P1433published inCurrent Opinion in HIV and AIDSQ15724409
P1476titleUsing nonhuman primates to model HIV transmission
P478volume8

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cites work (P2860)
Q39481098B Cell Responses Associated with Vaccine-Induced Delayed SIVmac251 Acquisition in Female Rhesus Macaques
Q98735530Characterization of Rhesus Macaque Liver-Resident CD49a+ NK Cells During Retrovirus Infections
Q37716218Expression, regulation, and function of drug transporters in cervicovaginal tissues of a mouse model used for microbicide testing
Q33602718Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild
Q59357086Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
Q35748138Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides
Q35794988HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model
Q36269097HIV transmission biology: translation for HIV prevention
Q38918138Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence
Q90616717In Vivo Validation of the Viral Barcoding of Simian Immunodeficiency Virus SIVmac239 and the Development of New Barcoded SIV and Subtype B and C Simian-Human Immunodeficiency Viruses
Q37208031Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques
Q35776556Macaque models of enhanced susceptibility to HIV.
Q59358396Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques
Q33900353Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events
Q59350268Nonhuman primate models of human viral infections
Q38849453Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection
Q92736069T Cells in the Female Reproductive Tract Can Both Block and Facilitate HIV Transmission
Q60307880Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge

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